Download or read book Solid State Nuclear Magnetic Resonance Studies of the Influenza Fusion Peptide Associated with Membrane Bilayers written by Paul Parkanzky and published by . This book was released on 2006 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Secondary Structure and Membrane Insertion of the Membrane associated Influenza Fusion Peptide Probed by Solid state Nuclear Magnetic Resonance written by Yan Sun and published by . This book was released on 2009 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Solid State Nuclear Magnetic Resonance of the HIV 1 and Influenza Fusion Peptides Associated with Membranes written by Michele L. Bodner and published by . This book was released on 2006 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Solid State NMR Studies of Structure and Dynamics of Membrane Associated Influenza Fusion Peptide written by Ujjayini Ghosh and published by . This book was released on 2016 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Solid state Nuclear Magnetic Resonance Studies of the Structure and Membrane Insertion of HIV Fusion Peptides written by Wei Qiang and published by . This book was released on 2009 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Solid state Nuclear Magnetic Resonance Structural Studies of the HIV 1 Fusion Peptide in the Membrane Environment written by Jun Yang and published by . This book was released on 2003 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Solid State Nuclear Magnetic Resonance Studies of the Structures Membrane Locations Cholesterol Contact and Membrane Motions of Membrane Associated HIV Fusion Peptide HFP written by Lihui Jia and published by . This book was released on 2017 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Solid State Nuclear Magnetic Resonance Studies of Model Biological Membranes written by Jose Silva Santos and published by . This book was released on 2001 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Investigation of the Structure and Dynamics of the M2 Transmembrane Peptide of the Influenza A Virus by Solid state Nuclear Magnetic Resonance written by Sarah Diane Cady and published by . This book was released on 2009 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Solid State Nuclear Magnetic Resonance Studies of Structures and Membrane Locations of Peptides written by Li Xie and published by . This book was released on 2014 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Solid state Nuclear Magnetic Resonance Investigations of the Influenza M2 Protein written by Jonathan Kyle Williams and published by . This book was released on 2017 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solid-state nuclear magnetic resonance (ssNMR) spectroscopy is a powerful technique that can be used to probe the structure and dynamics of biomolecules that are intractable to study by other structural biology methods. In this thesis, the mechanisms of conduction and gating are investigated in the influenza AM2 and BM2 proton channels bound to native-like lipid bilayers. Using pH-dependent 15N chemical shifts of the conserved Histidine residue, we have found that the proton conduction mechanism is the same in all of the M2 channels (WT AM2, S3 IN AM2, BM2) studied, and that the conduction cycle involves proton shuttling via hydrogen-bonding with water. For the first time, unambiguous structural restraints and sidechain dynamics were measured for the gating residue Trp4l in the AM2 channel. Trp4l was found to come into close contact with His37, close enough to undergo periodic cation-[pi] interactions that ensure unidirectional proton flow. Water-edited 1H-13C correlation experiments were used to investigate the channel hydration of AM2 and BM2 tetramers, and S12 in the C-terminal BM2 channel was found to have the largest pH-dependent spin-diffusion buildup of all residues studied, indicating that the BM2 serine triplet plays an important role in conduction. New ssNMR methods were developed to probe long-range 13C-13C distances, and to edit and clean-up crowded spectra of peptides and proteins containing aromatic residues. The ASSET technique removes the aliphatic cross peaks of all residues except for Phe, Trp, Tyr, and His in a two-dimensional 13C-13C correlation experiment, while a two-dimensional 13C-13C correlation experiment with gated-decoupling retains only non-protonated 3C resonances. The studies in this thesis have provided insight into the functionally important His and Trp residues in the M2 proton channel of the influenza virus, and provide new avenues for studying other peptides and proteins containing aromatic residues.
Download or read book Lipid Domains written by and published by Academic Press. This book was released on 2015-06-08 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Membranes is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. This volume offers an up to date presentation of current knowledge in the field of Lipid Domains. Written by leading experts Contains original material, both textual and illustrative, that should become a very relevant reference material The material is presented in a very comprehensive manner Both researchers in the field and general readers should find relevant and up-to-date information
Download or read book Peptide Lipid Interactions written by Sidney A. Simon and published by Academic Press. This book was released on 2002-11-13 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains a comprehensive overview of peptide-lipid interactions by leading researchers. The first part covers theoretical concepts, experimental considerations, and thermodynamics. The second part presents new results obtained through site-directed EPR, electron microscopy, NMR, isothermal calorimetry, and fluorescence quenching. The final part covers problems of biological interest, including signal transduction, membrane transport, fusion, and adhesion. Key Features * world-renowned experts * state-of-the-art experimental methods * monolayers, bilayers, biological membranes * theoretical aspects and computer simulations * rafts * synaptic transmission * membrane fusion * signal transduction
Download or read book Membrane Protein Structure Determination written by Jean-Jacques Lacapère and published by Methods in Molecular Biology. This book was released on 2010-08-06 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Membrane proteins, representing nearly 40% of all proteins, are key components of cells involved in many cellular processes, yet only a small number of their structures have been determined. Membrane Protein Structure Determination: Methods and Protocols presents many detailed techniques for membrane protein structure determination used today by bringing together contributions from top experts in the field. Divided into five convenient sections, the book covers various strategies to purify membrane proteins, approaches to get three dimensional crystals and solve the structure by x-ray diffraction, possibilities to gain structural information for a membrane protein using electron microscopy observations, recent advances in nuclear magnetic resonance (NMR), and molecular modelling strategies that can be used either to get membrane protein structures or to move from atomic structure to a dynamic understanding of a molecular functioning mechanism. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and easy to use, Membrane Protein Structure Determination: Methods and Protocols serves as an ideal reference for scientists seeking to further our knowledge of these vital and versatile proteins as well as our overall understanding of the complicated world of cell biology.
Download or read book Nuclear Magnetic Resonance written by G A Webb and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a spectroscopic method, nuclear magnetic resonance (NMR) has seen spectacular growth over the past two decades, both as a technique and in its applications. Today the applications of NMR span a wide range of scientific disciplines, from physics to biology to medicine. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive coverage of the literature on this topic. This Specialist Periodical Report reflects the growing volume of published work involving NMR techniques and applications, in particular NMR of natural macromolecules which is covered in two reports: "NMR of Proteins and Nucleic Acids" and "NMR of Carbohydrates, Lipids and Membranes". For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage. Seasoned practitioners of NMR will find this an invaluable source of current methods and applications. Volume 33 covers literature published from June 2002 to May 2003. Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.
Download or read book Phospholipids Handbook written by Gregor Cevc and published by CRC Press. This book was released on 1993-08-02 with total page 1162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Employing a multidisciplinary approach to phospholipid research, this work catalogues the current knowledge of this class of molecules and details the general, chemical, physical and structural properties of phospholipid monolayers and bilayers. Phospholipid applications are also covered.
Download or read book Nuclear Magnetic Resonance written by Krystyna Kamienska-Trela and published by Royal Society of Chemistry. This book was released on 2012 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a spectroscopic method, nuclear magnetic resonance (NMR) has seen spectacular growth, both as a technique and in its applications. Today's applications of NMR span a wide range of scientific disciplines, from physics to biology to medicine. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive coverage of the literature on this topic. This Specialist Periodical Report reflects the growing volume of published work involving NMR techniques and applications, in particular NMR of natural macromolecules, which is covered in two reports: NMR of Proteins and Nucleic Acids and NMR of Carbohydrates, Lipids and Membranes. In his foreword to the first volume, the then editor, Professor Robin Harris announced that the series would be a discussion on the phenomena of NMR and that articles will be critical surveys of the literature. This has certainly remained the case throughout the series, and in line with its predecessors, Volume 40 aims to provide a comprehensive coverage of the relevant NMR literature. For the current volume this relates to publications appearing between June 2009 and May 2010 (the nominal period of coverage in volume 1 was July 1970 to June 1971). Compared to the previous volume there are some new members of the reporting team. Theoretical Aspects of Spin-Spin Couplings are covered by J. Jazwinski, while E. Swiezewska and J.W̤jcik provide an account of NMR of Carbohydrates, Lipids and Membranes.
