Download or read book Sleep Wake Neurobiology and Pharmacology written by Hans-Peter Landolt and published by Springer Nature. This book was released on 2019-09-03 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume connects current ideas and concepts about sleep functions and circadian rhythms with the search for novel target-selective sleep-wake therapeutics. To do so, it provides a timely, state-of-the-art overview of sleep-wake mechanisms in health and disease, ongoing developments in drug discovery, and their prospects for the clinical treatment of sleep-disordered patients. It particularly focuses on the concept that sleep and wakefulness mutually affect each other, and the future therapeutic interventions with either sleep- or wake-promoting agents that are expected to not only improve the quality of sleep but also the waking behavior, cognition, mood and other sleep-associated physiological functions. The chapter 'Sleep Physiology, Circadian Rhythms, Waking Performance and the Development of Sleep-Wake Therapeutics' available open access under a CC BY 4.0 license at link.springer.com

Download or read book The Pharmacology of Sleep written by Anthony Kales and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of the current state of the clinical and basic science of the pharmacology of sleep. The information provided ranges from a historical perspective to current concepts of sleep mechanisms, including the interaction between pharmacology and sleep-wake regulation and between chronopahrmacology and sleep-wake rhythms. For the first time in one single volume, both the basic mechanisms of sleep, and the basic and clinical aspects of the pharmacology of sleep are dealt with in a thorough, comprehensive and authoritative manner. The chapters, written by the foremost scientific authorities in this field, integrate the latest information on the basic mechanisms of drugs as they relate to their effects on sleep.

Download or read book Sleep and Sleep Disorders written by Malcolm Lader and published by Springer Science & Business Media. This book was released on 2009-11-06 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many recent discoveries in both laboratory and clinical settings have greatly increased our understanding of sleep medicine and the relevant psychopharmacology. This timely book serves to present updated information about the neuropsychopharmacology of sleep as this field enters mainstream psychiatry, neurology and medicine This volume has assembled articles that summarize and review carefully, a chosen selection of the latest discoveries concerning sleep medicine, sleep physiology and sleep pharmacology. Outstanding contributions have been sought from acknowledged experts in their respective fields. The goal of the volume is to present the more recent developments and advances in the fields of sleep and neuropsychopharmacology, as well as to provide a context for considering them both in depth and from multidisciplinary perspectives. This volume brings together the collective expertise of clinicians and basic researchers who represent a range of interests in neuroscience, neuropharmacology, sleep physiology, and biological rhythms. Presenting a thoughtful balance of basic experimental and clinical facts and viewpoints, this book will serve as a foundation for understanding, and ultimately treating, sleep disorders.

Download or read book The Pharmacology of Sleep written by Anthony Kales and published by Springer. This book was released on 2011-09-27 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of the current state of the clinical and basic science of the pharmacology of sleep. The information provided ranges from a historical perspective to current concepts of sleep mechanisms, including the interaction between pharmacology and sleep-wake regulation and between chronopahrmacology and sleep-wake rhythms. For the first time in one single volume, both the basic mechanisms of sleep, and the basic and clinical aspects of the pharmacology of sleep are dealt with in a thorough, comprehensive and authoritative manner. The chapters, written by the foremost scientific authorities in this field, integrate the latest information on the basic mechanisms of drugs as they relate to their effects on sleep.

Download or read book The Gating and Maintenance of sleep and Wake New Circuits and Insights written by Michael Lazarus and published by Frontiers Media SA. This book was released on 2020-10-09 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Download or read book The Behavioral Molecular Pharmacological and Clinical Basis of the Sleep Wake Cycle written by Eric Murillo-Rodriguez and published by Academic Press. This book was released on 2019-03-26 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle provides the first comprehensive overview on the molecular methodologies used to evaluate sleep while also examining the cellular, biochemical, genetic, and therapeutic aspects of the sleep-wake cycle. There have been profound changes in the landscape of approaches to the study of sleep – mainly in the areas of molecular biology and molecular techniques. With this great focus on using multidisciplinary molecular methods, chapters address significant advances in the molecular mechanisms underlying sleep and the techniques researchers use to study this phenomenon. Written by world-leading experts in the area, this book is of great interest to researchers working in the sleep field and to anyone interested in one of the most mysterious phenomena in science – why we sleep and why we cannot survive without it. - Reviews the neurobiological and cellular mechanisms of the sleep-wake cycle - Provides the implications of sleep in health and disease - Contrasts different techniques to study molecular mechanisms - Contains case studies to better illustrate points - Covers sleep disturbance and health problems involved in sleep - Includes chapters on the ontogeny of sleep, along with multiple mechanisms for sleep generation

Download or read book Neurobiology of Sleep and Memory written by James McGaugh and published by Elsevier. This book was released on 2012-12-02 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of Sleep and Memory is the textual result of a symposium regarding the basic neurological processes in the storage of different kinds of memories (short-term and long-term). This book gives much focus on the relationship of sleep and memory and how they preserve personality and all its characteristics. The study of the interrelation of the two bodily processes also aims to help clarify neurological bases of disorders of sleep and memory and other forms of mental illness. This text consists of 23 chapters that encompass a wide span of topics regarding sleep and memory. Some of these topics include blood-brain barrier; protein synthesis in RNA and central nervous system; neuronal activity patterns during REM sleep; post-trial reticular stimulation; and sleep-related hormones. This book also discusses the phylogenetic correlations of sleep and memory not just in mammals but also in reptiles, amphibians, fishes, and birds. This reference material is a valuable source of information to both students and professionals studying biology, psychology, pharmacology, and neuroscience.

Download or read book Drug Treatment of Sleep Disorders written by Antonio Guglietta and published by Springer. This book was released on 2014-11-28 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following reviews on sleep physiology, regulation, pharmacology, and the neuronal networks regulating sleep and awakening, as well as a classification of sleep disorders, this book presents a number of major breakthroughs in the treatment of those disorders. These include recently approved drugs for treating insomnia, such as Doxepin; variations on previously approved molecules, e.g. Zolpidem sublingual preparation; or new chemical entities in advanced stages of clinical development, e.g. Orexin antagonists. Further topics discussed include drugs acting on the GABA receptor, such as Lorediplon and Eszopiclone; the treatment of excessive daytime drowsiness with cell therapy and drugs such as Modafinil, Armodafinil and Sodium oxybate; and the use of Tasimelteon in the treatment of circadian sleep disorders.

Download or read book Foundations of Psychiatric Sleep Medicine written by John W. Winkelman and published by Cambridge University Press. This book was released on 2010-12-23 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sleep-related complaints are extremely common across the spectrum of psychiatric illness. Accurate diagnosis and management of sleep disturbances requires an understanding of the neurobiological mechanisms underlying sleep and wakefulness, the characteristics of sleep disturbance inherent to psychiatric illness and primary sleep disorders, as well as the psychopharmacologic and behavioral treatments available. Foundations of Psychiatric Sleep Medicine provides a uniquely accessible, practical, and expert summary of current clinical concepts at the sleep-psychiatry interface. Topics covered include: basic principles in sleep science, clinical sleep history taking, primary sleep disorders in psychiatric contexts, and sleep disturbance across a range of mood, anxiety, psychotic, substance use, cognitive and developmental disorders. Written by outstanding experts in the field of sleep medicine and psychiatry, this academically rigorous and clinically useful text is an essential resource for psychiatrists, psychologists and other health professionals interested in the relationship between sleep and mental illness.

Download or read book Serotonin and Sleep Molecular Functional and Clinical Aspects written by Jaime M. Monti and published by Springer Science & Business Media. This book was released on 2008-03-04 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the neuropsychopharmacology of serotonin and its role in sleep and wakefulness, presenting neurochemical, electrophysiological, and neuropharmacological approaches to understand the mechanisms of serotonin and related substances. Covering core and contemporary topics in the area, this volume is valuable for all researchers interested in interdisciplinary studies concerning drugs affecting the central nervous system.

Download or read book Dopamine and Sleep written by Jaime M. Monti and published by Springer. This book was released on 2016-10-24 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive but highly readable compilation of papers on the role of dopamine in sleep and sleep disorders. Leading experts in sleep medicine, psychiatry and neuroendocrinology provide a broad perspective on the field, from established theories to the latest research advances. Accordingly, it represents an interdisciplinary, cutting-edge guide for sleep disorder specialists, sleep researchers, psychiatrists, neurologists, pulmonologists, psychologists, and behavioral sleep medicine specialists.

Download or read book Neuroendocrine Correlates of Sleep Wakefulness written by Daniel P. Cardinali and published by Springer Science & Business Media. This book was released on 2010-03-14 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the title suggests, and unlike other existing books on sleep medicine, Neuroendocrine Correlates of Sleep/Wakefulness will be devoted primarily to endocrine regulation of the behavioral state control. It will address a wide spectrum of sleep./wakefulness phenomena (both animals and humans), including pathogenesis, diagnosis, and management. From molecular biology to applied clinical therapy, sleep research has been transformed in the last few years from a research backwater to an important interdisciplinary field. Anyone who regularly reads the literature on sleep, biological rhythms, or neuroendocrinology is aware that one of the subspecialties within sleep medicine, the neuroendocrine correlates of sleep/wakefulness, has in particular experienced a growth rate that is even faster than that of the field as a whole. To a significant extent this has been due to the introduction of new research technologies. The widespread adoption of a range of new methods in sleep research has opened a window into activities at the cellular and molecular level, which previously had been tightly closed. Consequently these activities are being characterized with a degree of precision and sensitivity that is without precedent. This volume invites the reader to explore the new vistas that have been opened onto the neuroendocrine frontier of sleep medicine. The editors have selectively identified a number of key articles having a citation frequency, which is considerably above the norm or which otherwise have contributed importantly to defining the neuroendocrine perspective. This new volume on Neuroendocrine Correlates of Sleep/Wakefulness is an up-to-date resource of research summaries and reviews written by major contributors to the fields of sleep, biological rhythms and neuroendocrinology. Its coverage is broad and its basic and clinical science reviews are detailed. In this volume, an international team of experts discuss their latest ideas, concepts, methods, and interpretations with supporting examples. This volume is intended for advanced students and specialists in psychobiology, neuroscience, neuroendocrinology, and psychiatry but might also be interest to anyone concerned with understanding the Neuroendocrine correlates of sleep/wakefulness. The contributions are directed more towards providing an integrated view of the field from the perspective of the authors, rather than being a compendium of recent results. The intent is to provide a reference book for recent and future workers in this and related areas of medicine and biology. Each topic in this volume has received the attention of a panel of authors who have responded to our request to review and place into perspective the major issues, which will undoubtedly confront newcomers to the field. The topics dealt with in Neuroendocrine correlates of Sleep/wakefulness are both diverse and complex. The editors hope that this volume will provide an authoritative summary of important issues in the neuroendocrine correlates of sleep/wakefulness. We also hope that it will motivate new researchers to join the quest for solutions to the problems that have been identified by our contributing authors.

Download or read book Cannabinoids and Sleep written by Jaime M. Monti and published by Springer Nature. This book was released on 2021-02-03 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on cannabis and sleep is emerging with promising results. This book offers current and comprehensive knowledge on cannabinoid research results in connection with sleep. The volume covers aspects of the hemp plant Cannabis sativa, the pharmacology of cannabinoids, neurobiology and pharmacology of sleep and wakefulness, and the benefits and side effects of cannabis on the central nervous system. It further discusses the putative therapeutical properties of cannabinoids and endocannabinoids and their potential for the treatment of sleep disorders such as insomnia, obstructive sleep apnea, REM sleep behavior disorder, and restless legs syndrome. The book is written by medical and scientific experts in this field and intended for researchers from a range of disciplines such as biomedicine, biology, neurosciences, clinical medicine, neurology, and pharmacology.

Download or read book Sleep Deprivation written by Clete A. Kushida and published by CRC Press. This book was released on 2004-11-16 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exploring the wide array of structures, substances, and environments that are primary factors in the initiation or inhibition of sleep, this reference highlights key findings from respected professionals around the globe on the social and economic burden of impaired performance, productivity, and safety arising from sleep deprivation-studying pharm

Download or read book Orexin and Sleep written by Takeshi Sakurai and published by Springer. This book was released on 2015-09-22 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is intended for neuropharmacologists, psychopharmacologists, pharmacologists, pharmacists, sleep researchers, translational neuroscience researchers, and other basic researchers and clinical scientists interested in an interdisciplinary approach to sleep medicine. The level of the book is aiming at CNS researchers, drug development scientists, basic and clinical sleep researchers, as well as senior medical students and fellows in psychiatry and neurology. Orexin and Sleep provides a unique resource, giving a comprehensive and highly readable summary of the basic concepts in orexin biology and pharmacology along with clinical applications in sleep medicine in general, and narcolepsy in particular.

Download or read book The Orexin System Basic Science and Role in Sleep Pathology written by M.A. Steiner and published by Karger Medical and Scientific Publishers. This book was released on 2021-05-28 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: The orexin system, discovered in 1998, has emerged as a crucial player in regulating the sleep and wake balance inside our brain. This discovery has sparked a burst of novel and dynamic research on the physiology and pathology of sleep. The Orexin System: Basic Science and Role in Sleep Pathology honors this research and the authors share their ideas and perspectives on the novel developments within the field. The book examines the intricate role of the orexin system in regulating sleep and wake, and its interaction with other wake-regulating systems. The orexin system is dissected at the cellular and molecular level to explore the diversity of the orexin-producing neurons, their projections, and their signaling pathways. Additionally, the book discusses the diseases which are associated with a dysfunctional orexin system, such as narcolepsy, insomnia, substance abuse, and Alzheimer’s disease, and explores the new potential therapeutic applications derived from the burst of research around this fascinating system. This publication is essential reading for neurobiologists, neurologists, psychopharmacologists, sleep researchers, and other researchers and clinical scientists interested in sleep, sleep research, insomnia, and medicine in general.

Download or read book Biology of Sleep Substances written by Shojiro Inoue and published by CRC Press. This book was released on 1989-03-31 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: All aspects of sleep sciences are included in this excellent resource text, with special reference to sleep substances and sleep modulators. The historical development of the theories of sleep are reviewed in conjunction with the technical problems. All candidate substances are overviewed as to their sites of presence, chemical nature, bioassay techniques, physiological and pharmacological effects. On the basis of a standardized methodology developed by the author, sleep-modulatory characteristics of some substances are compared and evaluated in quantitative terms. The sleep regulatory mechanisms, which are composed of complex neurohumoral subsystems, are analyzed from the results of recent neurophysiological and neuroendocrinological experiments. Furthermore, an evolutionary aspect of sleep substances is taken into consideration. Chapters Highlight: Techniques for isolation and evaluation Prostaglandins Paradoxical sleep factors Sleep-promoting substances and nucleosides