Download or read book Skin Diseases After Organ Transplantation written by Sylvie Euvrard and published by John Libbey Eurotext. This book was released on 1998 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organ transplantation has been successfully performed over the last 35 years and the number of organ allograft recipients is steadily increasing. Long-term immunosuppression, necessary for good graft function, inevitably induces undesired effects (particularly infectious and neoplastic ones) among which cutaneous ones are very frequent and potentially life-threatening. This book deals with all aspects of cutaneous disorders that may be encountered in the setting of organ transplantation. It reflects the pioneering work performed since long by Dermatologists in Lyon, in collaboration with teams specialised in kidney, heart, lung, liver and pancreas transplantation.
Download or read book Skin Disease in Organ Transplantation written by Clark C. Otley and published by Cambridge University Press. This book was released on 2008-01-21 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Skin disease is a serious long-term problem for the recipients of solid organ transplants. The potent systemic immunosuppression therapy necessary to sustain a life-saving solid organ transplant is associated with many adverse cutaneous effects, including significantly increased rates of cutaneous malignancies, difficult-to-treat cutaneous infections, and cutaneous adverse manifestations of multiple medications. This book is the first scholarly compilation of the knowledge base surrounding the care of solid organ transplant recipients with dermatologic diseases. Supplemented with dozens of full-color photographs, this work brings together decades of knowledge into a cohesive format and establishes transplant dermatology as an important subspecialty within the field of dermatology and transplant medicine. Skin Disease in Organ Transplantation is an outstanding resource for transplant providers and dermatologists to determine the optimal diagnostic and therapeutic approach to the difficult problems of cutaneous disease in organ transplant recipients.
Download or read book Skin Cancer after Organ Transplantation written by Eggert Stockfleth and published by Springer Science & Business Media. This book was released on 2009-05-05 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organ transplantation has been performed for almost 40 years with steadily increasing success regarding long-time survival of the graft, as well as quality of life for the patient. However, graft tolerance only can be achieved via induction and maintenance of an impaired immunological surveillance. An increase of skin cancers as a consequence of the lowered cellular immunoresponse seems to parallel the overall increased long-time survival rate of organ transplant recipients. Against the background of chronic immunosuppression known risk factors like the amount of sun exposure prior and post transplantation, oncogenic viruses as well as the genetic background, and place of residence (latitude) are strongly related with the increased skin cancer incidence. The increasing incidence of non-melanoma skin cancer, paralleling a prolonged survival of patients after organ transplantation, represents a significant reason for morbidity and long-term morbidity in organ transplant recipients worldwide. The incidence of non-melanoma skin cancer in liver-, kidney- and heart transplant recipients varies from 1.5 to 22 %, 2 to 24 % and 6 to 34 % after 5 years post transplant. Ultraviolet radiation as well as immunosuppressive therapy are crucial risk-factors regarding the induction and progression of skin cancer. Ultraviolet radiation is related to the induction of DNA damage, as well as interference with Langerhans cell antigen presentation and a Th1 – Th2 shift induced via a release of IL-10. Whereas the overall duration of immunosuppression and the cumulative dosage applied are relevant parameters in the evaluation of an increased tumor risk, individual differences between specific immunosuppressive agents remain unclear. The workup of genetic as well as other unclear phenomenon like the reverse BCC/SCC ratio might shed some further light into the genesis and immunology of the non-melanoma skin cancer in general.
Download or read book Dermatology and Solid Organ Transplantation written by Nathalie C. Zeitouni and published by CRC Press. This book was released on 2021-08-15 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook brings together experts in the field of transplant dermatology to review both state of the art and practical knowledge regarding the clinical presentation and management of the various cutaneous diseases seen in patients with solid organ transplant. Practicing dermatologists, trainees, and other health care providers involved in the care of transplant patients can learn the current diagnostic and management options, and how to apply these guidelines and principles in their everyday practice.
Download or read book Transplantation Dermatology written by Peter Häusermann and published by Karger Medical and Scientific Publishers. This book was released on 2012 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential update and comprehensive review Patients undergoing solid organ and hematopoietic stem cell transplantation frequently develop skin diseases that can be challenging to themselves and their doctors. In the first part of this volume, prevalent epidemiological, clinical and histological skin problems of solid organ recipients are discussed. Pre- and posttransplant management as well as follow-up programs are presented focusing on European and Swiss guidelines. A special chapter is dedicated to immunosuppressive drugs considering current standards, and new and upcoming medication. The second part starts with a summary of historical aspects of hematopoietic stem cell transplantation, and proceeds with a description of skin manifestations of graft-versus-host disease and their therapy. Covered are early, late and very late periods after transplantation with a focus on recent consensus classification and treatment aspects of chronic graft-versus-host disease. The publication ends with a comprehensive review and practical guidance on photoprotection in transplant recipients. This book covers all the important dermatological aspects that should be considered in diagnosis and treatment of recipients of solid organ and hematopoietic stem cell transplants. It is intended as a guide for dermatologists, nephrologists, hemato-oncologists and all specialists involved in the field of transplantation.
Download or read book Atlas of Dermatologic Diseases in Solid Organ Transplant Recipients written by Jane Tomimori and published by Springer Nature. This book was released on 2022-11-14 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The number of solid organ transplant recipients is increasing worldwide every year, which has meant a significant improvement of recipient’s survival and quality of life. To prevent graft rejection, patients require long-term immunosuppression, which is responsible for their increased risk of neoplastic and infectious diseases. This practical and concise atlas presents the most important dermatoses in solid organ transplant recipients. Providing a guide to diagnosis and appropriate therapy, it helps dermatologists, general practitioners and physicians manage the dermatoses found in organ transplant recipients. The first three chapters discuss immunosuppressive regimens and the prevalence of dermatoses, while the other chapters approach the main diseases didactically, providing a large number of illustrations.
Download or read book Infectious Diseases in Solid Organ Transplant Recipients written by Oriol Manuel and published by Springer. This book was released on 2019-06-03 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes a practical approach to the diagnosis, management, and prevention of infectious complications in solid-organ transplant (SOT) candidates and recipients, based on both up-to-date clinical evidence and state of the art expert opinion from world-renowned experts in the field. The book is divided into three parts, the first of which explains risk assessment and the general approach to infectious diseases in the pre-, peri-, and early and late post-transplant periods. The remaining two sections address the prevention and treatment of infection with particular pathogens and the management of specific syndromes, such as pneumonia, CNS infections, UTIs, and skin infections. Infections in SOT recipients – often due to multidrug-resistant organisms – represent a major challenge. Preventive strategies need to be adapted according to the type of allograft and period after transplantation. Moreover, toxicity and drug interaction with immunosuppressive drugs must be taken into consideration when treating infectious complications. In explaining in depth how best to ensure allograft and patient survival, this book will be of value to infectious disease specialists and transplant physicians at all levels of experience.
Download or read book The European Blood and Marrow Transplantation Textbook for Nurses written by Michelle Kenyon and published by Springer. This book was released on 2018-03-14 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.
Download or read book Skin Cancer after Organ Transplantation written by Eggert Stockfleth and published by Springer. This book was released on 2010-11-16 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organ transplantation has been performed for almost 40 years with steadily increasing success regarding long-time survival of the graft, as well as quality of life for the patient. However, graft tolerance only can be achieved via induction and maintenance of an impaired immunological surveillance. An increase of skin cancers as a consequence of the lowered cellular immunoresponse seems to parallel the overall increased long-time survival rate of organ transplant recipients. Against the background of chronic immunosuppression known risk factors like the amount of sun exposure prior and post transplantation, oncogenic viruses as well as the genetic background, and place of residence (latitude) are strongly related with the increased skin cancer incidence. The increasing incidence of non-melanoma skin cancer, paralleling a prolonged survival of patients after organ transplantation, represents a significant reason for morbidity and long-term morbidity in organ transplant recipients worldwide. The incidence of non-melanoma skin cancer in liver-, kidney- and heart transplant recipients varies from 1.5 to 22 %, 2 to 24 % and 6 to 34 % after 5 years post transplant. Ultraviolet radiation as well as immunosuppressive therapy are crucial risk-factors regarding the induction and progression of skin cancer. Ultraviolet radiation is related to the induction of DNA damage, as well as interference with Langerhans cell antigen presentation and a Th1 – Th2 shift induced via a release of IL-10. Whereas the overall duration of immunosuppression and the cumulative dosage applied are relevant parameters in the evaluation of an increased tumor risk, individual differences between specific immunosuppressive agents remain unclear. The workup of genetic as well as other unclear phenomenon like the reverse BCC/SCC ratio might shed some further light into the genesis and immunology of the non-melanoma skin cancer in general.
Download or read book Principles and Practice of Transplant Infectious Diseases written by Amar Safdar and published by Springer. This book was released on 2019-06-13 with total page 1173 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive volume provides a platform from which both major and minor infectious diseases related issues are addressed in-depth among this highly susceptible population. The book begins with an overview of infections in various modalities. This is followed by chapters on clinical disorders, etiologic agents, therapeutics, and infection prevention. Chapters include easy-to-follow figures and tables, radiologic images, and pictorial demonstrations of various disease states to familiarize and reacquaint the transplant clinicians and surgeons in practice and training, and those belonging to subspecialties providing supportive care for these patients. Discussions to enumerate the noninfectious causes that mimic infectious diseases; clinical relevance and effective utility of existing and emerging diagnostic tools are presented throughout the book. Authored by leaders in their fields, this book is the go-to reference for management of patients undergoing hematopoietic and solid organ transplantation.
Download or read book Advances in Transplant Dermatology written by Fiona Zwald and published by Springer. This book was released on 2015-01-12 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an informative update on scientific advances relating to transplant dermatology that may be applicable to clinical practice. Commentary is provided on the emerging role of viruses in transplant dermatology, the management of skin disease secondary to transplant medication, sunscreen use in transplant recipients, the role of revision of immunosuppression, and advances in photodynamic therapy. The latest staging and management criteria for high-risk squamous cell carcinoma and the implications for clinical practice are then analyzed. Finally, the management of other cutaneous malignancies is discussed, covering malignant melanoma, Merkel cell carcinoma, and rarer tumors that also behave aggressively and require special consideration in solid organ transplant patients. Each particular advance is addressed in an individual chapter by leaders in the field. The book both expands current knowledge and complements previous textbooks on the subject.
Download or read book Janeway s Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Download or read book Chalk Talks in Internal Medicine written by Somnath Mookherjee and published by Springer Nature. This book was released on 2020-09-30 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides teaching scripts for medical educators in internal medicine and coaches them in creating their own teaching scripts. Every year, thousands of attending internists are asked to train the next generation of physicians to master a growing body of knowledge. Formal teaching time has become increasingly limited due to rising clinical workload, medical documentation requirements, duty hour restrictions, and other time pressures. In addition, today’s physicians-in-training expect teaching sessions that deliver focused, evidence-based content that is integrated into clinical workflow. In keeping with both time pressures and trainee expectations, academic internists must be prepared to effectively and efficiently teach important diagnostic and management concepts. A teaching script is a methodical and structured plan that aids in effective teaching. The teaching scripts in this book anticipate learners’ misconceptions, highlight a limited number of teaching points, provide evidence to support the teaching points, use strategies to engage the learners, and provide a cognitive scaffold for teaching the topic that the teacher can refine over time. All divisions of internal medicine (e.g. cardiology, rheumatology, and gastroenterology) are covered and a section on undifferentiated symptom-based presentations (e.g. fatigue, fever, and unintentional weight loss) is included. This book provides well-constructed teaching scripts for commonly encountered clinical scenarios, is authored by experienced academic internists and allows the reader to either implement them directly or modify them for their own use. Each teaching script is designed to be taught in 10-15 minutes, but can be easily adjusted by the reader for longer or shorter talks. Teaching Scripts in Internal Medicine is an ideal tool for internal medicine attending physicians and trainees, as well as physician’s assistants, nurse practitioners, and all others who teach and learn internal medicine.
Download or read book Skin Diseases in the Immunocompromised written by John C. Hall and published by Springer. This book was released on 2014-09-09 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the number of surviving immune suppressed patients continues its rapid increase, the skin manifestations have become increasingly important. AIDS patients and renal, heart, liver, bone marrow and lung transplant patients are surviving longer and are often experiencing skin side effects of immunity suppression. Diabetes is exploding in the USA and offers its own unique brand of immune suppressed skin diseases. Immunosuppressive drugs are being used more frequently and newer biologics and tyrosine kinase drugs have added to new categories of immune suppressed patients. This book aims to clearly elucidate the signs of immune suppressed skin disease to afford early diagnosis and management of this ever-increasing, diverse group of illnesses.
Download or read book Clinical Approach to Infection in the Compromised Host written by R. Rubin and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 703 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Infection in the Compromised Host" has become a classic chapter in textbooks devoted to infectious diseases and internal medicine. The numbers of compromised hosts are increasing in the era of modem medicine because of our expanded capabilities to deal with difficult diseases, especially neoplasms. As a consequence, microbiologic complications related to the intensive care administered to these patients are increasing as well. Under these circum stances, not only does the underlying illness create conditions favorable for the development of unusual infections, but often the therapy contributes to the acquisition of potential pathogens that turn into agents responsible for severe and frequently fatal disease. Granulocytopenia and immunosuppression have been the two key fac tors in predisposing patients with cancer and other serious diseases to severe bacterial infections. Colonization by hospital-acquired pathogens and breaks in the anatomic barriers-as a result of disease or medical intervention-have contributed to the high incidence of infectious diseases in these patients. Although there is some overlap between the types of infection in granulocytopenic and immunosuppressed hosts, each ofthese clinical entities has distinctive features thatjustify considering them separately, reserving the term immunocompromised hosts only when refer ring to patients who are predisposed to opportunistic infections. For about two decades, infections in granulocytopenic patients have attracted the atten tion of clinicians because they represent a model for the study of antimicrobial drugs in hosts deprived of an essential element of defense against bacterial infection, that is, an adequate number of normally functioning granulocytes.
Download or read book Therapeutic Immunosuppression written by Angus W. Thomson and published by Springer Science & Business Media. This book was released on 2001 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work has broad applications in clinical medicine, ranging from prevention and treatment of organ and bone marrow transplant rejection, management of various autoimmune disorders (for example, rheumatoid arthritis), skin disease and asthma. Whereas traditionally only a small repertoire of immunosuppressive agents was available for clinical use, recent discoveries have significantly increased the number of approved agents, resulting in numerous trials to further evaluate their potential. There is also considerable interest in the potential of cell-based therapies (particularly hematopoietic stem and dendritic cell therapy) of allo- and autoimmunity. Important recent advances in the immunotherapy of allergic diseases are also covered in this book. This volume is intended both for practising physicians and surgeons and for biomedical scientists at the graduate/postdoctoral levels, and is designed to provide the theory behind these various approaches to immunosuppression, and to provide state-of-the-art reviews of current developments in each area.
Download or read book Contemporary Liver Transplantation written by Cataldo Doria and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
