Download or read book Skin Cancer Detection by Oblique incidence Diffuse Reflectance Spectroscopy written by Elizabeth Brooks Smith and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Skin cancer is the most common form of cancer and it is on the rise. If skin cancer is diagnosed early enough, the survival rate is close to 90%. Oblique-incidence diffuse reflectance (OIR) spectroscopy offers a technology that may be used in the clinic to aid physicians in diagnosing both melanoma and non-melanoma skin cancers. The system includes a halogen light source, a fiber optic probe, an imaging spectrograph, a charge coupled device (CCD) camera, and a computer. Light is delivered to the skin surface via optical fibers in the probe. After interacting with the skin, the light is collected and sent to the spectrograph that generates optical spectra. Images and histopathological diagnoses were obtained from 250 lesions at the University of Texas M.D. Anderson Cancer Center (Melanoma and Skin Center). To classify OIR data, an image processing algorithm was developed and evaluated for both pigmented and non-pigmented lesions. The continuous wavelet transform and the genetic algorithm were employed to extract optimal classification features. Bayes decision rule was used to categorize spatiospectral images based on the selected classification features. The overall classification accuracy for pigmented melanomas and severely dysplastic nevi is 100%. The overall classification accuracy for non-pigmented skin cancers and severely dysplastic nevi is 93.33%. Oblique-incidence diffuse reflectance spectroscopy and the developed algorithms have high classification rates and may prove useful in the clinic as the process is fast, noninvasive and accurate.

Download or read book Non invasive Optical Detection of Epithelial Cancer Using Oblique Incidence Diffuse Reflectance Spectroscopy written by Alejandro Garcia-Uribe and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation describes the design, fabrication and testing of an oblique incidence diffuse reflectance spectrometry (OIDRS) system for in-vivo and noninvasive detection of epithelial cancer. Two probes were fabricated using micromachining technology, which plays a significant role in the probe development by enabling device miniaturization, low-cost fabrication and precise assembly. The fist probe was developed and clinically tested for skin cancer detection. This probe consists of three source fibers, two linear array of collection fibers and four micromachined positioning devices for accurate alignment of the fibers. The spatially resolved diffuse reflectance spectra from 167 pigmented and 78 non-pigmented skin abnormalities were measured and used to design a set of classifiers to separate them into benign or malignant ones. These classifiers perform with an overall classification rate of 91%. The absorption and reduced scattering coefficient spectra were estimated to link the anatomic and physiologic properties of the lesions with the optical diagnosis. The melanoma cases presented larger average absorption and reduced scattering spectra than the dysplastic and benign ones. A second probe was designed to demonstrate the feasibility of a miniaturized?side viewing? optical sensor probe for OIDRS. The sensor probe consists of a lithographically patterned polymer waveguides chip and two micromachined positioning substrates. This miniaturize probe was used to measure twenty ex-vivo esophageal samples. Two statistical classifiers were designed to separate the esophageal cases. The first one distinguishes benign and low dysplastic from high dysplastic and cancerous lesions. The second classifier separates benign lesions from low dysplastic ones. Both classifiers generated a classification rate of 100%.

Download or read book Diffuse Reflectance Spectroscopy for Noninvasive Diagnosis of Skin Cancer written by Kirrily D. Wong and published by . This book was released on 2001 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Melanomas New Insights for the Healthcare Professional 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-07-22 with total page 789 pages. Available in PDF, EPUB and Kindle. Book excerpt: Melanomas: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Melanomas: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Melanomas: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Imaging in Dermatology written by Michael R. Hamblin and published by Academic Press. This book was released on 2016-07-29 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging in Dermatology covers a large number of topics in dermatological imaging, the use of lasers in dermatology studies, and the implications of using these technologies in research. Written by the experts working in these exciting fields, the book explicitly addresses not only current applications of nanotechnology, but also discusses future trends of these ever-growing and rapidly changing fields, providing clinicians and researchers with a clear understanding of the advantages and challenges of laser and imaging technologies in skin medicine today, along with the cellular and molecular effects of these technologies. Outlines the fundamentals of imaging and lasers for dermatology in clinical and research settings Provides knowledge of current and future applications of dermatological imaging and lasers Coherently structured book written by the experts working in the fields covered

Download or read book Melanoma written by Howard L. Kaufman and published by Springer. This book was released on 2015-11-24 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Melanoma is one of the most types of cancer. When melanoma is detected at an early stage, treatment is highly successful, but outcomes can be poor when the disease is advanced. There has been significant progress in our understanding of the molecular biology, genetics, and immunology of melanoma over the past decade. This has been accompanied by rapid advances in therapeutic strategies for patients with melanoma. This book provides the clinician and the researcher with a broad understanding of the molecular and cellular pathogenesis of melanoma, explores the clinical characteristics and criteria for clinical and pathological staging of the disease, and provides an overview of current and evolving treatment strategies in the adjuvant, metastatic, and preventive settings. The treatment of special populations and rare variants of melanoma that often present particular clinical challenges is also covered. Authored by international experts in melanoma biology and clinical management, this volume concisely explains how to diagnose, treat, and prevent melanoma while reviewing advances in basic science and providing an overview of innovative approaches still under development.

Download or read book Multimodal Optical Diagnostics of Cancer written by Valery V. Tuchin and published by Springer Nature. This book was released on 2020-10-23 with total page 605 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an in-depth description and discussion of different multi-modal diagnostic techniques for cancer detection and treatment using exact optical methods, their comparison, and combination. Coverage includes detailed descriptions of modern state of design for novel methods of optical non-invasive cancer diagnostics; multi-modal methods for earlier cancer diagnostic enhancing the probability of effective cancer treatment; modern clinical trials with novel methods of clinical cancer diagnostics; medical and technical aspects of clinical cancer diagnostics, and long-term monitoring. Biomedical engineers, cancer researchers, and scientists will find the book to be an invaluable resource. Introduces optical imaging strategies; Focuses on multimodal optical diagnostics as a fundamental approach; Discusses novel methods of optical non-invasive cancer diagnostics.

Download or read book Endoscopic Diagnostics in Biomedicine written by N. Sujatha and published by Momentum Press. This book was released on 2019-03-04 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concise, yet comprehensive, coverage of various endoscopic forms as provided in this book will help the reader generate new knowledge in this field. Endoscopy has been in practice for many years in diagnostic medicine. From a simple image collection device, the endoscope has grown into an instrument that incorporates multiple imaging modalities to extract structural and functional information from different parts of the human body. Multimodality endoscopes are discussed in detail in this book, along with their clinical applications. The book is intended for graduate-level students as a quick reference to understand the evolving trends in endoscopic design research. The challenges that remain unaddressed could potentially be explored by biomedical researchers to advance this technology to realize the concept of optical biopsy during routine endoscopic examinations. The book portrays the endoscope as a purely optical instrument, and hence hybrid modes of endoscopic imaging are not covered.

Download or read book Intelligent Decision Technologies written by Ireneusz Czarnowski and published by Springer Nature. This book was released on 2022-07-26 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers selected papers from the KES-IDT 2022 Conference, held in Rhodes, Greece on June 20–22, 2022. The book presents and discusses the latest research results and generates new ideas in the field of intelligent decision-making. The range of topics discussed are classification, prediction, data analysis, big data, data science, decision support, knowledge engineering, and modeling in diverse areas such as finance, cybersecurity, economics, health, management, and transportation. The problems in Industry 4.0 and IoT are also addressed. The book contains several sections devoted to specific topics, such as intelligent data processing and its applications, high-dimensional data analysis and its applications, multi-criteria decision analysis—theory and applications, large-scale systems for intelligent decision-making and knowledge engineering, decision technologies and related topics in big data analysis of social and financial issues, and decision-making theory for economics.

Download or read book Translational Research in Biomedical Sciences Recent Progress and Future Prospects written by Krupakar Parthasarathy and published by Springer Nature. This book was released on with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Diagn stico Por Imagen En Dermatolog a written by Michael R. Hamblin and published by Elsevier. This book was released on 2017-06-24 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnóstico por imagen en dermatología cubre las más importantes técnicas de imagen diagnóstica empleadas en la especialidad, tanto desde un punto de vista clínico como por lo que respecta a las implicaciones de su uso en investigación. Se abordan no solo las aplicaciones actuales sino también las tendencias futuras de este campo en constante y rápida evolución, proporcionando a clínicos e investigadores una comprensión clara y precisa de las ventajas y retos del empleo actual de las diversas técnicas de imagen en dermatología, incluyendo sus efectos a nivel celular y molecular. Proporciona información sobre un extenso repertorio de técnicas, desde las más convencionales hasta las más novedosas, desde un punto de vista clínico y de investigación. Aborda el diagnóstico por imagen de enfermedades como la queratosis actínica, el melanoma cutáneo, el carcinoma de células de Merkel, la hidradenitis supurativa, etc. Es de fácil consulta gracias a la estructura clara y sistemática de la información, ilustrada con numerosas fotografías e imágenes en color. Se dirige a dermatólogos clínicos y a investigadores en las áreas de dermatología, radiología, farmacéutica, biología molecular, diagnóstico y tratamiento del cáncer, y biotecnología. Obra que contiene toda la información esencial para el empleo de las técnicas de imagen en el diagnósticos, tratamiento, monitorización y an ́ ́alisis de las enfermedades cutáneas, de la mano de un prestigiosos equipo de expertos. Cubre las más importantes técnicas de imagen diagnóstica empleadas en la especialidad, tanto des un punto de vista clínico como por lo que respecta a las implicaciones de su uso en investigación. Obra de fácil consulta gracias a la estructura clara y sistemática de la información, profusamente ilustrada. Aborda el diagnóstico por imagen de enfermedades como la queratosis actínica, el melanoma cutáneo, el carcinoma de células de Merkel, la hisdradenitis supurativa, etc. Se dirige a dermatólogos clínicos y a investigadores en las áreas de dermatología, radiología, farmacéutica, biología molecular, diagnóstico y tratamiento del cáncer y biotecnología.

Download or read book Optical Imaging for Biomedical and Clinical Applications written by Ahmad Fadzil Mohamad Hani and published by CRC Press. This book was released on 2017-10-30 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical imaging is a rapidly emerging imaging technique that has been successfjully translated into biomedical applications ranging from clinical diagnosis to molecular biology. This book includes an introductory section to explore various optical imaging devices and their functionality and roles for biomedical applications such as dermatology and ophthalmology. Recent developments as exemplified with the authors research are explored in detail. In depth discussion of other disease conditions and their diagnosis with optical imaging techniques are also covered.

Download or read book Biomedical Optics written by Lihong V. Wang and published by John Wiley & Sons. This book was released on 2012-09-26 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This entry-level textbook, covering the area of tissue optics, is based on the lecture notes for a graduate course (Bio-optical Imaging) that has been taught six times by the authors at Texas A&M University. After the fundamentals of photon transport in biological tissues are established, various optical imaging techniques for biological tissues are covered. The imaging modalities include ballistic imaging, quasi-ballistic imaging (optical coherence tomography), diffusion imaging, and ultrasound-aided hybrid imaging. The basic physics and engineering of each imaging technique are emphasized. A solutions manual is available for instructors; to obtain a copy please email the editorial department at [email protected].

Download or read book Hyper spectral Diffuse Reflectance Spectroscopy Imaging Towards the Identification of Non melanoma Skin Cancers written by Sheldon Floyd Bish and published by . This book was released on 2013 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-melanoma skin cancer is the most prevalent malignancy in the world, with over a million annual positive diagnoses in the United States. If left untreated, these cancers cause morbidity and in rare cases, can become life threatening. The key to identifying and characterizing these tumors in the earliest stages, where they are most treatable lie in margin delineation in order to prevent recurrence. The visual obscurity of tumor morphology and physiology can make early detection a difficult task for dermatologists, particularly in the initial stages of cancer development. Tumor resection is a common course of action once they are discovered; however, there is a high recurrence rate due to incomplete removal of the malignant tissue. This dissertation presents an imaging system that can capture the spectral signatures correlating with morphological and physiological changes that accompany skin dysplasia. With this system, we may improve tumor margin delineation, reducing the number of incomplete tumor biopsies and false negative screenings. As an initial step of this process, we begin with a non-contact point sampling diffuse reflectance probe that mitigates the adverse effects of traditional contact probing. Validation of this probe is performed using tissue simulating phantoms spanning a biologically relevant range of optical and physiological properties to ensure that the non-contact format will not hinder performance relative to the contact probe. Cross polarization and auto-focus mechanisms were included in the design to reduce specular reflections and movement artifacts from in vivo measurements. This non-contact design was further developed into a platform for investigating the role of sampling geometry on diffuse reflectance measurements with the addition of a DMD spatial filter. Finally, we developed a hyperspectral DRSi system for the acquisition of wide-field maps of optical and physiological properties that is currently being tested on patients undergoing skin cancer screenings. The spectral output of this system has been validated for scattering and absorption across biologically relevant ranges using tissue simulating phantoms. The DRSi system was optimized for portability, ergonomics and resolution.

Download or read book The Measurement of Diffuse Reflectance of Cloth and Skin Samples written by Leo J. Krolak and published by . This book was released on 1955 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biomedical Engineering Frontier Research and Converging Technologies written by Hanjoong Jo and published by Springer. This book was released on 2015-07-23 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with an integrative overview of the latest research and developments in the broad field of biomedical engineering. Each of the chapters offers a timely review written by leading biomedical engineers and aims at showing how the convergence of scientific and engineering fields with medicine has created a new basis for practically solving problems concerning human health, wellbeing and disease. While some of the latest frontiers of biomedicine, such as neuroscience and regenerative medicine, are becoming increasingly dependent on new ideas and tools from other disciplines, the paradigm shift caused by technological innovations in the fields of information science, nanotechnology, and robotics is opening new opportunities in healthcare, besides dramatically changing the ways we actually practice science. At the same time, a new generation of engineers, fluent in many different scientific “languages,” is creating entirely new fields of research that approach the “old” questions from a new and holistic angle. The book reports on the scientific revolutions in the field of biomedicine by describing the latest technologies and findings developed at the interface between science and engineering. It addresses students, fellows, and faculty and industry investigators searching for new challenges in the broad biomedical engineering fields.

Download or read book Optical Detection of Cancer written by Arlen D. Meyers and published by World Scientific. This book was released on 2012 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ch. 1. The optical detection of cancer: an introduction / Toby Steele and Arlen Meyers -- ch. 2. Optical coherence tomography in oral cancer / Shahareh Sabet and Petra Wilder-Smith -- ch. 3. Optical coherence tomography in laryngeal cancer / Marcel Kraft and Christoph Arens -- ch. 4. Fluorescence imaging of the upper aerodigestive tract / Christian Stephan Betz, Andreas Leunig and Christoph Arens -- ch. 5. Photodynamic diagnosis and photodynamic therapy techniques / Zheng Huang -- ch. 6. OCT detection of lung cancer / S. Murgu and M. Brenner -- ch. 7. Diffuse optical spectroscopy and imaging in breast cancer / Albert E. Cerussi and Bruce J. Tromberg -- ch. 8. OCT for skin cancer / Gordon McKenzie and Adam Meekings