Download or read book Skeletal Impact of Disease written by Bruce M. Rothschild and published by New Mexico Museum of Natural History and Science. This book was released on 2006 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ortner s Identification of Pathological Conditions in Human Skeletal Remains written by Jane Buikstra and published by Academic Press. This book was released on 2019-01-29 with total page 859 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ortner's Identification of Pathological Conditions in Human Skeletal Remains, Third Edition, provides an integrated and comprehensive treatment of the pathological conditions that affect the human skeleton. As ancient skeletal remains can reveal a treasure trove of information to the modern orthopedist, pathologist, forensic anthropologist, and radiologist, this book presents a timely resource. Beautifully illustrated with over 1,100 photographs and drawings, it provides an essential text and material on bone pathology, thus helping improve the diagnostic ability of those interested in human dry bone pathology. Presents a comprehensive review of the skeletal diseases encountered in archaeological human remains Includes more than 1100 photographs and line drawings illustrating skeletal diseases, including both microscopic and gross features Based on extensive research on skeletal paleopathology in many countries Reviews important theoretical issues on how to interpret evidence of skeletal disease in archaeological human populations
Download or read book Genetics of Bone Biology and Skeletal Disease written by Rajesh V. Thakker and published by Academic Press. This book was released on 2017-10-31 with total page 878 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics of Bone Biology and Skeletal Disease, Second Edition, is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid and related disorders, and vitamin D and renal disorders. The first section is specifically devoted to providing an overview of bone biology and structure, joint and cartilage biology, principles of endocrine regulation of bone, and the role of neuronal regulation and energy homeostasis. The second section reviews the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, copy number variation, prospects of gene therapy, pharmacogenomics, genetic testing and counseling, as well as the generation and utilizing of mouse models. The third section details advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasias, and rarer bone disorders. The fourth section highlights the central role of the parathyroids in calcium and skeletal homeostasis by reviewing the molecular genetics of: hyperparathyroidism, hypoparathyrodism, endocrine neoplasias, and disorders of the PTH and calcium-sensing receptors. The fifth section details molecular and cellular advances across associated renal disorders such as vitamin D and rickets. Identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluation of treatments Demonstrates how the interactions between bone and joint biology, physiology, and genetics have greatly enhanced the understanding of normal bone function as well as the molecular pathogenesis of metabolic bone disorders Summarizes the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder
Download or read book Identification of Pathological Conditions in Human Skeletal Remains written by Donald J. Ortner and published by Academic Press. This book was released on 2003-01-06 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: Identicication of Pathological Conditions in Human Skeletal Remains provides an integrated and comprehensive overview of pathological conditions that affect the human skeleton. The primary objective is to assist those who conduct research on archeological skeletal remains in interpreting abnormal conditions that they might encounter in the course of their research. However, there is much that ancient skeletal remains can reveal to the modern orthopedist, pathologist, forensic anthropologist, and radiologist about the skeletal manifestations of diseases that are rarely encountered in modern medical practice. The medical historian will find information on the antiquity and early geographical distribution of many diseases. All of the major categories of disease that affect bone are reviewed on the basis of the literature on the radiology and pathology of these diseases. This review is followed by a discussion of the literature on the paleopathological cases thought to represent each of the morbid categories affecting bone. This book is based on extensive individual and collaborative research by the author and contributing authors on the known parameters of basic calcified tissue biology and modern skeletal diseases and their expression in antiquity. The monograph provides essential text and illustrative materials on bone pathology, which will improve the diagnostic ability of those interested in human dry bone pathology. It also provides time depth to our understanding of the effect of disease on past human populations. Key Features * Comprehensive review of skeletal diseases encountered in archeological human remains * More than 1100 photographs and line drawings illustrating skeletal diseases including both microscopic and gross features * Based on extensive research on skeletal paleopathology in many countries for over 35 years * Review of important theoretical issues in interpreting evidence of skeletal disease in archeological human populations
Download or read book New Insights into Estrogen Estrogen Receptor Effects in the Cardiac and Skeletal Muscle written by Georgios Kararigas and published by Frontiers Media SA. This book was released on 2020-05-06 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Companion to Paleopathology written by Anne L. Grauer and published by John Wiley & Sons. This book was released on 2011-12-12 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Companion to Paleopathology offers a comprehensive overview of this rapidly growing sub- field of physical anthropology. Presents a broad overview of the field of paleopathology, integrating theoretical and methodological approaches to understand biological and disease processes throughout human history Demonstrates how paleopathology sheds light on the past through the analysis of human and non-human skeletal materials, mummified remains and preserved tissue Integrates scientific advances in multiple fields that contribute to the understanding of ancient and historic diseases, such as epidemiology, histology, radiology, parasitology, dentistry, and molecular biology, as well as archaeological, archival and historical research. Highlights cultural processes that have an impact on the evolution of illness, death and dying in human populations, including subsistence strategies, human environmental adaptations, the effects of malnutrition, differential access to resources, and interpersonal and intercultural violence
Download or read book Modern Paleopathology The Study of Diagnostic Approach to Ancient Diseases their Pathology and Epidemiology written by Bruce M. Rothschild and published by Springer Nature. This book was released on 2023-09-27 with total page 873 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of paleopathology has two very different constituencies, the medical scientist and the zoologist/paleontologist/anthropologist. Their investigative procedures and professional jargon are different, sometimes to the point of mutual incomprehensibility. Paleontologists/anthropologists/zoologists have a limited data base for the characterization and interpretation of pathology. This must come from the human and veterinary medical experience. What, beyond intellectual satisfaction, can the health care community expect from this relationship? The past history of the appearance and dispersal of infectious disease and cancer is of considerable theoretical importance and leads to new insights on the nature and transmission of diseases that are otherwise ambiguous. The discovery of rheumatoid arthritis in pre-Columbian North America exemplifies insights gained. The current effort delineates osseous impact of disease (as manifest in clinical populations diagnosed in life), representation in the zoologic, paleontologic and anthropologic record, and assessment techniques that can be confidently applied. The chapters form “columns” that provide the foundation for scientific critical thinking. The actual integration of the information is in its application. Our purpose is to provide a data base and atlas of actually documented skeletal impact of diseases (as population phenomenon), an initial data base of reported skeletal pathology, and a methodology for expanding this to new arenas. The first section of the book examines the scientific basis of paleopathology, its transition from speculation-based musings, resolution of misconceptions and the denouement of paleo-epidemiology. The second section provides holistic analysis of the gamut of pathology/diseases with significant skeletal impact, with a validated archeologic/zoological/paleontological record. The third section provides a glossary to resolve the semantic challenges inherent to interdisciplinary efforts. The fourth section provides an atlas of pathology representation in the fossil record. Ultimately, this book intends to present a scientifically-validated approach to recognition of disease in the archeological, zoological and paleontological record, superseding previous speculation-based offerings.
Download or read book Impact of Microbiome on Gut Mucosal Immunity in Health and Disease written by Oscar Gilberto Gomez-Duarte and published by Frontiers Media SA. This book was released on 2022-11-07 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mandell Douglas and Bennett s Principles and Practice of Infectious Diseases written by John E. Bennett, MD, MACP and published by Elsevier Health Sciences. This book was released on 2014-08-28 with total page 5094 pages. Available in PDF, EPUB and Kindle. Book excerpt: After thirty five years, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. John E. Bennett and Raphael Dolin along with new editorial team member Dr. Martin Blaser have meticulously updated this latest edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition helps you identify and treat whatever infectious disease you see. Get the answers to questions you have with more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than you'll find in any other infectious disease resource. Find the latest diagnoses and treatments for currently recognized and newly emerging infectious diseases, such as those caused by avian and swine influenza viruses. Put the latest knowledge to work in your practice with new or completely revised chapters on influenza (new pandemic strains); new Middle East respiratory syndrome (MERS) virus; probiotics; antibiotics for resistant bacteria; antifungal drugs; new antivirals for hepatitis B and C; Clostridium difficile treatment; sepsis; advances in HIV prevention and treatment; viral gastroenteritis; Lyme disease; Helicobacter pylori; malaria; infections in immunocompromised hosts; immunization (new vaccines and new recommendations); and microbiome. Benefit from fresh perspectives and global insights from an expanded team of international contributors. Find and grasp the information you need easily and rapidly with newly added chapter summaries. These bulleted templates include diagnosis, therapy, and prevention and are designed as a quick summary of the chapter and to enhance relevancy in search and retrieval on Expert Consult. Stay current on Expert Consult with a thorough and regularly scheduled update program that ensures access to new developments in the field, advances in therapy, and timely information. Access the information you need easily and rapidly with new succinct chapter summaries that include diagnosis, therapy, and prevention. Experience clinical scenarios with vivid clarity through a richly illustrated, full-color format that includes 1500 photographs for enhanced visual guidance.
Download or read book Frontiers in Skeletal Muscle Wasting Regeneration and Stem Cells written by Carlos Hermano J. Pinheiro and published by Frontiers Media SA. This book was released on 2016-05-25 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: The search for knowledge on cellular and molecular mechanisms involved in skeletal muscle mass homeostasis and regeneration is an exciting scientific area and extremely important to develop therapeutic strategies for neuromuscular disorders and conditions related to muscle wasting. The mechanisms involved in the regulation of skeletal muscle mass and regeneration consist of molecular signaling pathways modulating protein synthesis and degradation, bioenergetics alterations and preserved function of muscle stem cells. In the last years, different kinds of stem cells has been reported to be localized into skeletal muscle (satellite cells, mesoangioblasts, progenitor interstitial cells and others) or migrate from non-muscle sites, such as bone marrow, to muscle tissue in response to injury. In addition, myogenic progenitor cells are also activated in skeletal muscle wasting disorders. The goal of this research topic is to highlight the available knowledge regarding skeletal muscle and stem cell biology in the context of both physiological and pathological conditions. Our purpose herein is to facilitate better dissemination of research into skeletal muscle physiology field. Frontiers in Physiology is a journal indexed in: PubMed Central, Scopus, Google Scholar, DOAJ, CrossRef.
Download or read book Obesity written by Debasis Bagchi and published by CRC Press. This book was released on 2012-07-06 with total page 993 pages. Available in PDF, EPUB and Kindle. Book excerpt: The World Health Organization (WHO) has declared obesity a global epidemic. Its prevalence has more than doubled since 1980, causing a myriad of health problems for children and adults. Obesity: Epidemiology, Pathophysiology, and Prevention, Second Edition explores the molecular mechanisms and pathophysiology leading to obesity and metabolic disord
Download or read book Perspectives in Avian Skeletal Systems and Skeletal Abnormalities written by Chongxiao (Sean) Chen and published by Frontiers Media SA. This book was released on 2023-10-16 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: The avian skeletal system is drawing increasing attention from researchers because it serves as a unique research model to study bone metabolism and pathologies, as well as the importance of bone health and its relationship with animal productivity and welfare. The avian skeleton is a delicate system providing structural support to the bird and minerals for eggshell formation, meanwhile, functioning as an immune organ. There is a lack of complete understanding of the physiological difference between mammalian and avian bones, the impact of genetic improvements, the interaction between immunity and bone health, the avian bone 3D structural development and turnover, the biological function of avian bone, and its relationship with animal well-being. Additionally, skeletal abnormalities can have a serious effect on poultry farming whereby conditions such as osteomyelitis, rickets and chondrodystrophy, among others, can cause changes in gait patterns, reduced walking ability and other pathophysiologies with subsequent detrimental effects on feed conversion and growth, as well as economic losses.
Download or read book Fossil Record 3 written by Robert M. Sullivan and published by New Mexico Museum of Natural History and Science. This book was released on 2011 with total page 747 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Oxford Textbook of Clinical and Biochemical Disorders of the Skeleton written by Roger Smith and published by Oxford University Press. This book was released on 2016 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated and revised textbook provides comprehensive coverage of common polygenic and rare monogenic disorders, emphasising advances in bone cell biology and human skeletal disease. Accessible and well-illustrated, this concise account of metabolic bone disease is designed for postgraduates and clinicians.
Download or read book Skeletal Development and Remodeling in Health Disease and Aging Volume 1068 written by Mone Zaidi and published by Wiley-Blackwell. This book was released on 2006-06-23 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of how the skeleton is remodeled and repaired has been enormously expanded in the past decade. Using advanced molecular technologies including transgenesis, gene knockout, and gene array, we are gaining a better understanding of both the precise pathways through which osteoblasts lay down new bone and how osteoclasts remove old bone. These studies have not only helped us understand the basic biological properties of the skeleton and how it responds to hormonal, cytokine, and mechanical stimulation, but also, in some instances, clarified the source of pathophysiology. The eventual goal of such discoveries is to lay down a firm scientific foundation for the identification of novel cellular and molecular targets for future drug development. This volume presents the significant headway that scientists have made in this undertaking and the book is organized around four broad themes: skeletal development and repair, molecular endocrinology of bone, bone cell biology, and conservation of skeletal integrity. Also included are papers that focus on current and emerging therapies for osteoporosis. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.
Download or read book Physical activity and fitness for the prevention and management of bone diseases written by Luis Gracia-Marco and published by Frontiers Media SA. This book was released on 2023-05-04 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nutrition in the Prevention and Treatment of Disease written by Ann M. Coulston and published by Academic Press. This book was released on 2008-03-28 with total page 921 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference addresses basic principles and concepts that are central to the major clinical nutrition-related activities, such as nutritional assessment and monitoring, current theoretical base and knowledge of efficacious interventions, interactions between genetic and nutritional factors, and the use and interpretation of population-based or clinical epidemiological evidence.
