Download or read book Bones and Cartilage written by Brian K. Hall and published by Academic Press. This book was released on 2014-12-23 with total page 911 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bones and Cartilage provides the most in-depth review and synthesis assembled on the topic, across all vertebrates. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage develop in embryos and are maintained in adults, how bone is repaired when we break a leg, or regenerates when a newt grows a new limb, or a lizard a new tail. The second edition of Bones and Cartilage includes the most recent knowledge of molecular, cellular, developmental and evolutionary processes, which are integrated to outline a unified discipline of developmental and evolutionary skeletal biology. Additionally, coverage includes how the molecular and cellular aspects of bones and cartilage differ in different skeletal systems and across species, along with the latest studies and hypotheses of relationships between skeletal cells and the most recent information on coupling between osteocytes and osteoclasts All chapters have been revised and updated to include the latest research. Offers complete coverage of every aspect of bone and cartilage, with updated references and extensive illustrations Integrates development and evolution of the skeleton, as well a synthesis of differentiation, growth and patterning Treats all levels from molecular to clinical, embryos to evolution, and covers all vertebrates as well as invertebrate cartilages Includes new chapters on evolutionary skeletal biology that highlight normal variation and variability, and variation outside the norm (neomorphs, atavisms) Updates hypotheses on the origination of cartilage using new phylogenetic, cellular and genetic data Covers stem cells in embryos and adults, including mesenchymal stem cells and their use in genetic engineering of cartilage, and the concept of the stem cell niche

Download or read book The Skeletal System written by Caroline Arnold and published by LernerClassroom. This book was released on 2005-01-01 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains how the different types of bones of the body work harmoniously together.

Download or read book Skeletal Muscle Circulation written by Ronald J. Korthuis and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this treatise is to summarize the current understanding of the mechanisms for blood flow control to skeletal muscle under resting conditions, how perfusion is elevated (exercise hyperemia) to meet the increased demand for oxygen and other substrates during exercise, mechanisms underlying the beneficial effects of regular physical activity on cardiovascular health, the regulation of transcapillary fluid filtration and protein flux across the microvascular exchange vessels, and the role of changes in the skeletal muscle circulation in pathologic states. Skeletal muscle is unique among organs in that its blood flow can change over a remarkably large range. Compared to blood flow at rest, muscle blood flow can increase by more than 20-fold on average during intense exercise, while perfusion of certain individual white muscles or portions of those muscles can increase by as much as 80-fold. This is compared to maximal increases of 4- to 6-fold in the coronary circulation during exercise. These increases in muscle perfusion are required to meet the enormous demands for oxygen and nutrients by the active muscles. Because of its large mass and the fact that skeletal muscles receive 25% of the cardiac output at rest, sympathetically mediated vasoconstriction in vessels supplying this tissue allows central hemodynamic variables (e.g., blood pressure) to be spared during stresses such as hypovolemic shock. Sympathetic vasoconstriction in skeletal muscle in such pathologic conditions also effectively shunts blood flow away from muscles to tissues that are more sensitive to reductions in their blood supply that might otherwise occur. Again, because of its large mass and percentage of cardiac output directed to skeletal muscle, alterations in blood vessel structure and function with chronic disease (e.g., hypertension) contribute significantly to the pathology of such disorders. Alterations in skeletal muscle vascular resistance and/or in the exchange properties of this vascular bed also modify transcapillary fluid filtration and solute movement across the microvascular barrier to influence muscle function and contribute to disease pathology. Finally, it is clear that exercise training induces an adaptive transformation to a protected phenotype in the vasculature supplying skeletal muscle and other tissues to promote overall cardiovascular health. Table of Contents: Introduction / Anatomy of Skeletal Muscle and Its Vascular Supply / Regulation of Vascular Tone in Skeletal Muscle / Exercise Hyperemia and Regulation of Tissue Oxygenation During Muscular Activity / Microvascular Fluid and Solute Exchange in Skeletal Muscle / Skeletal Muscle Circulation in Aging and Disease States: Protective Effects of Exercise / References

Download or read book Skeletal Tissue Mechanics written by R. Bruce Martin and published by Springer. This book was released on 2015-10-29 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook describes the biomechanics of bone, cartilage, tendons and ligaments. It is rigorous in its approach to the mechanical properties of the skeleton yet it does not neglect the biological properties of skeletal tissue or require mathematics beyond calculus. Time is taken to introduce basic mechanical and biological concepts, and the approaches used for some of the engineering analyses are purposefully limited. The book is an effective bridge between engineering, veterinary, biological and medical disciplines and will be welcomed by students and researchers in biomechanics, orthopedics, physical anthropology, zoology and veterinary science. This book also: Maximizes reader insights into the mechanical properties of bone, fatigue and fracture resistance of bone and mechanical adaptability of the skeleton Illustrates synovial joint mechanics and mechanical properties of ligaments and tendons in an easy-to-understand way Provides exercises at the end of each chapter

Download or read book Genetics of Bone Biology and Skeletal Disease written by Rajesh V. Thakker and published by Academic Press. This book was released on 2017-10-31 with total page 878 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics of Bone Biology and Skeletal Disease, Second Edition, is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid and related disorders, and vitamin D and renal disorders. The first section is specifically devoted to providing an overview of bone biology and structure, joint and cartilage biology, principles of endocrine regulation of bone, and the role of neuronal regulation and energy homeostasis. The second section reviews the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, copy number variation, prospects of gene therapy, pharmacogenomics, genetic testing and counseling, as well as the generation and utilizing of mouse models. The third section details advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasias, and rarer bone disorders. The fourth section highlights the central role of the parathyroids in calcium and skeletal homeostasis by reviewing the molecular genetics of: hyperparathyroidism, hypoparathyrodism, endocrine neoplasias, and disorders of the PTH and calcium-sensing receptors. The fifth section details molecular and cellular advances across associated renal disorders such as vitamin D and rickets. Identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluation of treatments Demonstrates how the interactions between bone and joint biology, physiology, and genetics have greatly enhanced the understanding of normal bone function as well as the molecular pathogenesis of metabolic bone disorders Summarizes the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder

Download or read book Kinesiology E Book written by Joseph E. Muscolino and published by Elsevier Health Sciences. This book was released on 2010-10-15 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: See the body's bones, joints, and muscles in action! Highly visual and in full color, Kinesiology: The Skeletal System and Muscle Function makes it easy to understand kinesiology concepts and how they would be applied to the treatment of dysfunction. It contains over 1,200 illustrations, including a bone atlas that shows every bone in the human body and six chapters with detailed, illustrated coverage of joints. Written by noted educator and author Joseph E. Muscolino, this book clearly depicts how muscles function as movers, antagonists, and stabilizers. This edition expands its reach to athletic training with two new chapters on stretching and strengthening exercises. This title includes additional digital media when purchased in print format. For this digital book edition, media content may not be included Companion DVD includes over one hour of video demonstrating all the major joint actions of the human body, with a voiceover explanation of the names of the motions, the planes in which motion occurs, and the axes around which motion occurs. Unique! A focus on the needs of massage therapists and bodyworkers makes it easier to apply kinesiology concepts to the practice of massage therapy. Unique! A complete bone atlas includes over 100 full-color photographs showing every bone in the human body. 1,200 full-color illustrations help you understand concepts relating to the bones of the human body, joints of the human body, and muscle function parts. A logical, easy-to-reference format moves from basics (like parts of the body) to more difficult topics (such as microphysiology). Six chapters on joints cover structure, function, and terminology, with specific illustrations on each joint in the human body: joints of the axial body, joints of the upper extremity, and joints of the lower extremity. Student-friendly features in each chapter include an outline, learning objectives, overview, key terms with pronunciations, and word origins designating the Latin or Greek derivative. Clear, simple explanations make it easy to understand kinesiology concepts, including muscle contraction(s), coordination of muscles with movement, core stabilization, posture, exercise, reflexes, and how the nervous system controls and directs the muscular system. Expert author Joseph E. Muscolino, DC, offers years of experience in the study of muscles and muscle function, as well as bodywork and massage, and conveys that information in an understandable format.

Download or read book Nutrition and Skeletal Muscle written by Stéphane Walrand and published by Academic Press. This book was released on 2018-10-24 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrition and Skeletal Muscle provides coverage of the evidence of dietary components that have proven beneficial for bettering adverse changes in skeletal muscle from disuse and aging. Skeletal muscle is the largest tissue in the body, providing elements of contraction and locomotion and acting as an important contributor to whole body protein and amino metabolism, glucose disposal and lipid metabolism. However, muscle loss, atrophy or weakness can occur when there are metabolic imbalances, disuse or aging. This book addresses the topic by providing insight and research from international leaders, making it the go-to reference for those in skeletal muscle physiology. Provides an understanding of the crucial role of skeletal muscle in global metabolic homeostasis regulation Delivers the information needed to understand the utilization of crucial supplements for the preservation of skeletal muscle Presents insights on research from international leaders in the field

Download or read book Research Methods in Human Skeletal Biology written by Elizabeth A. DiGangi and published by Academic Press. This book was released on 2012-09-25 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research Methods in Human Skeletal Biology serves as the one location readers can go to not only learn how to conduct research in general, but how research is specifically conducted within human skeletal biology. It outlines the current types of research being conducted within each sub-specialty of skeletal biology, and gives the reader the tools to set up a research project in skeletal biology. It also suggests several ideas for potential projects. Each chapter has an inclusive bibliography, which can serve as a good jumpstart for project references. Provides a step-by-step guide to conducting research in human skeletal biology Covers diverse topics (sexing, aging, stature and ancestry estimation) and new technologies (histology, medical imaging, and geometric morphometrics) Excellent accompaniment to existing forensic anthropology or osteology works

Download or read book Identification of Pathological Conditions in Human Skeletal Remains written by Donald J. Ortner and published by Academic Press. This book was released on 2003-01-10 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt: Identification of Pathological Conditions in Human Skeletal Remains provides an integrated and comprehensive treatment of pathological conditions that affect the human skeleton. There is much that ancient skeletal remains can reveal to the modern orthopaedist, pathologist, forensic anthropologist, and radiologist about the skeletal manifestations of diseases that are rarely encountered in modern medical practice. Beautifully illustrated with over 1,100 photographs and drawings, this book provides essential text and materials on bone pathology, which will improve the diagnostic ability of those interested in human dry bone pathology. It also provides time depth to our understanding of the effect of disease on past human populations. Comprehensive review of skeletal diseases encountered in archeological human remains More than 1100 photographs and line drawings illustrating skeletal disease including both microscopic and gross features Based on extensive research on skeletal paleopathology in many countries for over 35 years Review of important theoretical issues in interpreting evidence of skeletal disease in archeological human populations

Download or read book Ortner s Identification of Pathological Conditions in Human Skeletal Remains written by Jane Buikstra and published by Academic Press. This book was released on 2019-01-29 with total page 859 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ortner's Identification of Pathological Conditions in Human Skeletal Remains, Third Edition, provides an integrated and comprehensive treatment of the pathological conditions that affect the human skeleton. As ancient skeletal remains can reveal a treasure trove of information to the modern orthopedist, pathologist, forensic anthropologist, and radiologist, this book presents a timely resource. Beautifully illustrated with over 1,100 photographs and drawings, it provides an essential text and material on bone pathology, thus helping improve the diagnostic ability of those interested in human dry bone pathology. Presents a comprehensive review of the skeletal diseases encountered in archaeological human remains Includes more than 1100 photographs and line drawings illustrating skeletal diseases, including both microscopic and gross features Based on extensive research on skeletal paleopathology in many countries Reviews important theoretical issues on how to interpret evidence of skeletal disease in archaeological human populations

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Skeletal Muscle written by Brian R. MacIntosh and published by Human Kinetics. This book was released on 2006 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides readers with a detailed understanding of the different facets of muscle physiology. Examines motoneuron and muscle structure and function. It is intended for those need to know about skeletal muscle--from undergraduate and graduate students gaining advanced knowledge in kinesiology to physiotherapists, physiatrists, and other professionals whose work demands understanding of muscle form and function.

Download or read book The Skeletal System written by Rebecca Pettiford and published by Blastoff! Readers. This book was released on 2019-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human body has 206 bones, and each has a special job to do! From giving the body shape to making blood cells, the skeletal system truly is the body's foundation! Through labeled diagrams and carefully defined terms, readers can easily follow the skeletal system's many roles.

Download or read book Bones written by Gillian Houghton and published by The Rosen Publishing Group. This book was released on 2007 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the bones found in the human body.

Download or read book Skeletal System written by Karen Haywood and published by Marshall Cavendish. This book was released on 2009 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Discusses the parts that make up the human skeletal system, what can go wrong, how to treat those illnesses and diseases, and how to stay healthy"--Provided by publisher.

Download or read book Botulinum Neurotoxins written by Andreas Rummel and published by Springer. This book was released on 2015-01-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but deadly disease botulism, military and terrorist intended to misuse this sophisticated molecule as biological weapon. This caused its classification as select agent category A by the Centers for Diseases Control and Prevention and the listing in the Biological and Toxin Weapons Convention. Later, the civilian use of BoNT as long acting peripheral muscle relaxant has turned this molecule into an indispensable pharmaceutical world wide with annual revenues >$1.5 billion. Also basic scientists value the botulinum neurotoxin as molecular tool for dissecting mechanisms of exocytosis. This book will cover the most recent molecular details of botulinum neurotoxin, its mechanism of action as well as its detection and application.

Download or read book Skeletal Anatomy of the Newborn Primate written by Timothy D. Smith and published by Cambridge University Press. This book was released on 2020-05-28 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first clearly-illustrated, comparative book on developmental primate skeletal anatomy, focused on the highly informative newborn stage.