Download or read book Single photon Detector Arrays for Time resolved Fluorescence Imaging written by Marek Gersbach and published by . This book was released on 2009 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Time correlated single photon counting written by Desmond O'Connor and published by Academic Press. This book was released on 2012-12-02 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Time-correlated Single Photon Counting has been written in the hope that by relating the authors' experiences with a variety of different single photon counting systems, they may provide a useful service to users and potential users of this formidably sensitive technique. Of all the techniques available to obtain information on the rates of depopulation of excited electronic singlet states of molecular species, monitoring of fluorescence provides, in principle, the simplest and most direct measure of concentration. This volume comprises eight chapters, with the first focusing on the time dependence and applications of fluorescence. Succeeding chapters go on to discuss basic principles of the single photon counting lifetime measurement; light sources; photomultipliers; electronics; data analysis; nanosecond time-resolved emission spectroscopy; time dependence of fluorescence anisotropy. This book will be of interest to practitioners in the field of chemistry.
Download or read book Photon Counting Image Sensors written by Eric R. Fossum and published by MDPI. This book was released on 2018-07-06 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Photon-Counting Image Sensors" that was published in Sensors
Download or read book Single Photon Imaging written by Peter Seitz and published by Springer Science & Business Media. This book was released on 2011-08-03 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: The acquisition and interpretation of images is a central capability in almost all scientific and technological domains. In particular, the acquisition of electromagnetic radiation, in the form of visible light, UV, infrared, X-ray, etc. is of enormous practical importance. The ultimate sensitivity in electronic imaging is the detection of individual photons. With this book, the first comprehensive review of all aspects of single-photon electronic imaging has been created. Topics include theoretical basics, semiconductor fabrication, single-photon detection principles, imager design and applications of different spectral domains. Today, the solid-state fabrication capabilities for several types of image sensors has advanced to a point, where uncoooled single-photon electronic imaging will soon become a consumer product. This book is giving a specialist ́s view from different domains to the forthcoming “single-photon imaging” revolution. The various aspects of single-photon imaging are treated by internationally renowned, leading scientists and technologists who have all pioneered their respective fields.
Download or read book Modern Tools for Time Resolved Luminescence Biosensing and Imaging written by and published by Frontiers Media SA. This book was released on 2021-09-01 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Photonics for Biomedical Engineering written by Aaron H.-P. Ho and published by Springer. This book was released on 2016-09-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanophotonics has emerged rapidly into technological mainstream with the advent and maturity of nanotechnology available in photonics and enabled many new exciting applications in the area of biomedical science and engineering that were unimagined even a few years ago with conventional photonic engineering techniques. Handbook of Nanophotonics in Biomedical Engineering is intended to be a reliable resource to a wealth of information on nanophotonics that can inspire readers by detailing emerging and established possibilities of nanophotonics in biomedical science and engineering applications. This comprehensive reference presents not only the basics of nanophotonics but also explores recent experimental and clinical methods used in biomedical and bioengineering research. Each peer-reviewed chapter of this book discusses fundamental aspects and materials/fabrication issues of nanophotonics, as well as applications in interfaces, cell, tissue, animal studies, and clinical engineering. The organization provides quick access to current issues and trends of nanophotonic applications in biomedical engineering. All students and professionals in applied sciences, materials, biomedical engineering, and medical and healthcare industry will find this essential reference book highly useful.
Download or read book High Performance Silicon Imaging written by Daniel Durini and published by Woodhead Publishing. This book was released on 2019-10-19 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: High Performance Silicon Imaging: Fundamentals and Applications of CMOS and CCD Sensors, Second Edition, covers the fundamentals of silicon image sensors, addressing existing performance issues and current and emerging solutions. Silicon imaging is a fast growing area of the semiconductor industry. Its use in cell phone cameras is already well established, with emerging applications including web, security, automotive and digital cinema cameras. The book has been revised to reflect the latest state-of-the art developments in the field, including 3D imaging, advances in achieving lower signal noise, and new applications for consumer markets. The fundamentals section has also been expanded to include a chapter on the characterization and testing of CMOS and CCD sensors that is crucial to the success of new applications. This book is an excellent resource for both academics and engineers working in the optics, photonics, semiconductor and electronics industries. Covers the fundamentals of silicon-based image sensors and technical advances, focusing on performance issues Looks at image sensors in applications, such as mobile phones, scientific imaging, and TV broadcasting, and in automotive, consumer and biomedical applications Addresses the theory behind 3D imaging and 3D sensor development, including challenges and opportunities
Download or read book Quantum Nano Photonics written by Baldassare Di Bartolo and published by Springer. This book was released on 2018-09-19 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together more closely researchers working in the two fields of quantum optics and nano-optics and provides a general overview of the main topics of interest in applied and fundamental research. The contributions cover, for example, single-photon emitters and emitters of entangled photon pairs based on epitaxially grown semiconductor quantum dots, nitrogen vacancy centers in diamond as single-photon emitters, coupled quantum bits based on trapped ions, integrated waveguide superconducting nanowire single-photon detectors, quantum nano-plasmonics, nanosensing, quantum aspects of biophotonics and quantum metamaterials. The articles span the bridge from pedagogical introductions on the fundamental principles to the current state-of-the-art, and are authored by pioneers and leaders in the field. Numerical simulations are presented as a powerful tool to gain insight into the physical behavior of nanophotonic systems and provide a critical complement to experimental investigations and design of devices.
Download or read book Single Photon Generation and Detection written by and published by Academic Press. This book was released on 2013-11-29 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: Single-photon generation and detection is at the forefront of modern optical physics research. This book is intended to provide a comprehensive overview of the current status of single-photon techniques and research methods in the spectral region from the visible to the infrared. The use of single photons, produced on demand with well-defined quantum properties, offers an unprecedented set of capabilities that are central to the new area of quantum information and are of revolutionary importance in areas that range from the traditional, such as high sensitivity detection for astronomy, remote sensing, and medical diagnostics, to the exotic, such as secretive surveillance and very long communication links for data transmission on interplanetary missions. The goal of this volume is to provide researchers with a comprehensive overview of the technology and techniques that are available to enable them to better design an experimental plan for its intended purpose. The book will be broken into chapters focused specifically on the development and capabilities of the available detectors and sources to allow a comparative understanding to be developed by the reader along with and idea of how the field is progressing and what can be expected in the near future. Along with this technology, we will include chapters devoted to the applications of this technology, which is in fact much of the driver for its development. This is set to become the go-to reference for this field. Covers all the basic aspects needed to perform single-photon experiments and serves as the first reference to any newcomer who would like to produce an experimental design that incorporates the latest techniques Provides a comprehensive overview of the current status of single-photon techniques and research methods in the spectral region from the visible to the infrared, thus giving broad background that should enable newcomers to the field to make rapid progress in gaining proficiency Written by leading experts in the field, among which, the leading Editor is recognized as having laid down the roadmap, thus providing the reader with an authenticated and reliable source
Download or read book Advanced Photon Counting written by Peter Kapusta and published by Springer. This book was released on 2015-05-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on Time-Correlated Single Photon Counting (TCSPC), a powerful tool allowing luminescence lifetime measurements to be made with high temporal resolution, even on single molecules. Combining spectrum and lifetime provides a “fingerprint” for identifying such molecules in the presence of a background. Used together with confocal detection, this permits single-molecule spectroscopy and microscopy in addition to ensemble measurements, opening up an enormous range of hot life science applications such as fluorescence lifetime imaging (FLIM) and measurement of Förster Resonant Energy Transfer (FRET) for the investigation of protein folding and interaction. Several technology-related chapters present both the basics and current state-of-the-art, in particular of TCSPC electronics, photon detectors and lasers. The remaining chapters cover a broad range of applications and methodologies for experiments and data analysis, including the life sciences, defect centers in diamonds, super-resolution microscopy, and optical tomography. The chapters detailing new options arising from the combination of classic TCSPC and fluorescence lifetime with methods based on intensity fluctuation represent a particularly unique highlight.
Download or read book Single Photon Generation and Detection written by Sergio Cova and published by Elsevier Inc. Chapters. This book was released on 2013-11-29 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: This chapter presents a broad review of the principle, design, fabrication, operation, and performance of single-photon avalanche diodes (SPADs), and provides a comparative basis to assess the relative merits of the wide variety of devices and techniques covered. Particular attention is paid to the design of and operation of both silicon and high-speed-gated InGaAs/InP detection systems, as well as array-based systems.
Download or read book Nano Net written by Alexandre Schmid and published by Springer Science & Business Media. This book was released on 2009-10-06 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the proceedings of the 4th International Conference on Nano-Networks, Nano-Net 2009, held in Lucerne, Switherland, in October 2009. The 36 invited and regular papers address the whole spectrum of Nano-Networks and spans topis like modeling, simulation, statdards, architectural aspects, novel information and graph theory aspects, device physics and interconnects, nanorobotics as well as nano-biological systems. The volume also contains the workshop on Nano-Bio-Sensing Paradigms as well as the workshop on Brain Inspired Interconnects and Circuits.
Download or read book Analog Electronics for Radiation Detection written by Renato Turchetta and published by CRC Press. This book was released on 2017-12-19 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analog Electronics for Radiation Detection showcases the latest advances in readout electronics for particle, or radiation, detectors. Featuring chapters written by international experts in their respective fields, this authoritative text: Defines the main design parameters of front-end circuitry developed in microelectronics technologies Explains the basis for the use of complementary metal–oxide semiconductor (CMOS) image sensors for the detection of charged particles and other non-consumer applications Delivers an in-depth review of analog-to-digital converters (ADCs), evaluating the pros and cons of ADCs integrated at the pixel, column, and per-chip levels Describes incremental sigma–delta ADCs, time-to-digital converter (TDC) architectures, and digital pulse-processing techniques complementary to analog processing Examines the fundamental parameters and front-end types associated with silicon photomultipliers used for single visible-light photon detection Discusses pixel sensors with per-pixel TDCs, channel density challenges, and emerging 3D technologies interconnecting detectors and electronics Thus, Analog Electronics for Radiation Detection provides a single source for state-of-the-art information on analog electronics for the readout of radiation detectors.
Download or read book Photodetectors written by Sanka Gateva and published by BoD – Books on Demand. This book was released on 2012-03-23 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book some recent advances in development of photodetectors and photodetection systems for specific applications are included. In the first section of the book nine different types of photodetectors and their characteristics are presented. Next, some theoretical aspects and simulations are discussed. The last eight chapters are devoted to the development of photodetection systems for imaging, particle size analysis, transfers of time, measurement of vibrations, magnetic field, polarization of light, and particle energy. The book is addressed to students, engineers, and researchers working in the field of photonics and advanced technologies.
Download or read book FRET and FLIM Techniques written by Theodorus W. J. Gadella and published by Elsevier. This book was released on 2011-07-29 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume reviews the techniques Förster Resonance Energy Transfer (FRET) and Fluorescence Lifetime Imaging Microscopy (FLIM) providing researchers with step by step protocols and handy hints and tips. Both have become staple techniques in many biological and biophysical fields.
Download or read book Development of Shallow Trench Isolation Bounded Single photon Avalanche Detectors for Acousto optic Signal Enhancement and Frequency Up conversion written by Mark J. Hsu and published by . This book was released on 2010 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation describes the development of the first CMOS single photon avalanche diode (SPAD) fabricated in a deep-submicron commercial CMOS process. Single photon detection is often necessary for high-sensitivity, high dynamic range time-resolved optical measurements in diverse applications in medicine, biology, military, and optical communication links. Single photon avalanche diode (SPAD) detectors have become the device of choice and have made strong gains in recent years. They are unique in that they provide digital information of the arrival of an individual photon impinging on the detector, thus being a very powerful tool when time-of-arrival information and timing resolution are crucial. Timing precision of the detector will improve contrast in fluorescence lifetime imaging and resolution in laser ranging applications. Traditionally, single photon detectors have been fabricated using custom processes because of the conditions under which the devices operate under. Because of the need to sustain high currents and high electric-fields, special custom fabrication processes have been developed. These fabrication processes have great benefits such as low-noise, high detection efficiencies, low jitter, and tailored spectral responses towards longer wavelengths. However, these fabrication techniques are often undesirable due to increased capacitance from off-chip quenching, recharging, and processing circuitry, resulting in longer detector dead times and slower sampling rates. Furthermore, large-scale production and scalability to arrays is impractical. There has been a trend towards using Complementary Metal-Oxide-Semiconductor (CMOS) technology for constructing SPAD pixels and arrays with integrated circuitry to overcome these limitations. Though commercial CMOS technologies are by nature, generic, and are not designed for SPAD devices, they can still offer considerable advantages in certain areas where custom processes lack. This dissertation describes the modeling, simulation, and full characterization of a CMOS STI-bounded Single Photon Avalanche Diode (SPAD). State-of-the-art sampling rates, dead-time, and jitter performance are characterized, and the device is compared to traditional diffused-guard ring structures for solid-state SPADs. Further, novel applications of the CMOS SPAD for acousto-optic signal enhancement and frequency up-conversion of 1550nm are described. An optical scatter system for acoustic characterization of ultrasound responsive microbubbles and particles is designed and developed. Further, a novel method of fluorescence modulation using dye-loaded microbubbles is demonstrated.
Download or read book Radiation Effects in Semiconductors written by Krzysztof Iniewski and published by CRC Press. This book was released on 2018-09-03 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Space applications, nuclear physics, military operations, medical imaging, and especially electronics (modern silicon processing) are obvious fields in which radiation damage can have serious consequences, i.e., degradation of MOS devices and circuits. Zeroing in on vital aspects of this broad and complex topic, Radiation Effects in Semiconductors addresses the ever-growing need for a clear understanding of radiation effects on semiconductor devices and circuits to combat potential damage it can cause. Features a chapter authored by renowned radiation authority Lawrence T. Clark on Radiation Hardened by Design SRAM Strategies for TID and SEE Mitigation This book analyzes the radiation problem, focusing on the most important aspects required for comprehending the degrading effects observed in semiconductor devices, circuits, and systems when they are irradiated. It explores how radiation interacts with solid materials, providing a detailed analysis of three ways this occurs: Photoelectric effect, Compton effect, and creation of electron-positron pairs. The author explains that the probability of these three effects occurring depends on the energy of the incident photon and the atomic number of the target. The book also discusses the effects that photons can have on matter—in terms of ionization effects and nuclear displacement Written for post-graduate researchers, semiconductor engineers, and nuclear and space engineers with some electronics background, this carefully constructed reference explains how ionizing radiation is creating damage in semiconducting devices and circuits and systems—and how that damage can be avoided in areas such as military/space missions, nuclear applications, plasma damage, and X-ray-based techniques. It features top-notch international experts in industry and academia who address emerging detector technologies, circuit design techniques, new materials, and innovative system approaches.
