Download or read book Simulation of Mass Transfer Phenomenon in a CAD Drug Eluting Stent System written by Md. Iqbal Hossain and published by Anchor Academic Publishing. This book was released on 2017-09 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronary artery disease is the most common type of heart diseases and the leading cause of death worldwide due to heart disease. It occurs when the arteries that supply blood to the heart become narrowed or blocked by a buildup of cholesterol and other material at the inner wall of the artery. Limitation of blood flow to the heart causes ischemia of the myocardial cells. Myocardial cells may die from lack of oxygen and this is called a myocardial infarction – or more commonly: a heart attack. Treatment options include medication, surgery or catheter-based procedures. Several types of catheter-based procedures are available. During balloon angioplasty, a special balloon catheter is passed into the narrowed segment of the artery and expands the balloon, which thus opens the artery and compresses the blockage against the wall of the artery. Stents are very small metal mesh-tubes that can be inserted via a balloon catheter into the narrowed segment of the artery. When the balloon is inflated, the stent expands and is embedded into the artery vessel wall, which thus opens the previously narrowed segment of artery. The balloon is then deflated and removed along with the catheter, and the stent is left behind to serve as a metal framework for the artery. In case of drug eluting stents a certain amount of anti-flammating drug is loaded in the coating over the base stent. This drug is released at the wall of diseased artery so that restenosis cannot take place at the place of artery where the stent has been implanted. In this thesis a drug eluting stent was studied where there was a biodegradable coating over a bare metal stent in which there was some amount of therapeutic drug. The degradation of the biodegradable coating layer thickness was determined with respect to time which was actually representing the remaining drug concentration in the coating layer. Then using this variable drug concentration as the drug concentration at initial tissue layer concentration profile of drug in tissue layer with respect to time and position was determined using finite volume algorithm, where this algorithm was coded using MATLAB programming language.
Download or read book Drug Coated Balloons written by Bernardo Cortese and published by Springer. This book was released on 2019-06-19 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive, up-to-date summary of drug-coated balloon (DCB) technology and the role of DCBs in the treatment of coronary and peripheral arterial disease. In addition to clear explanation of how DCBs works, readers will find an enlightening analysis of the mistakes and successes of the past decade and the emergence of the latest delivery systems, which combine a more deliverable device with much improved drug delivery to the vessel wall. The full range of current applications of DCBs are reviewed in detail, drawing on the latest scientific evidence. Due attention is paid to newer devices, with provision of technical insights and documentation of the available clinical data. Ongoing research projects, remaining technical challenges, likely future directions, and reimbursement issues are also carefully considered. This book will be a useful tool for any interventional cardiologist, interventional radiologist, or vascular surgeon who wishes to acquire a deep knowledge of this technology and its application in both coronary and peripheral interventions.
Download or read book Primary Angioplasty written by Timothy J Watson and published by Springer. This book was released on 2018-07-13 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. This quick-reference handbook offers a concise and practical review of key aspects of the treatment of ST-segment elevation myocardial infarction (STEMI) in the era of primary percutaneous coronary intervention (PPCI). In the context of STEMI, PPCI is the preferred mode of emergency revascularization. Access to PPCI is rapidly increasing and is now routinely practiced in both general and specialist hospitals and there has been a recent emphasis on developing STEMI networks to enhance and expedite the referral pathway. This coupled with concurrent developments to enhance the safety and efficacy of the PPCI procedure has heralded an era where STEMI interventions are increasingly considered an important subspecialty within interventional cardiology. Written by leading cardiologists who have been instrumental in the adoption of PPCI in their respective institutions, the book provides junior and senior cardiologists alike with insightful and thought-provoking tips and tricks to enhance the success of PPCI procedures, which may in turn translate into direct improvements in outcomes. The book is also relevant for healthcare providers and emergency department physicians.
Download or read book Biomechanics of Coronary Atherosclerotic Plaque written by and published by Academic Press. This book was released on 2020-03-15 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomechanics of Coronary Atherosclerotic Plaque: From Model to Patient, First Edition, is the first comprehensive text to focus on important biomechanical studies conducted in the last decade that have increased our understanding of coronary atherosclerotic plaque initiation, growth, and rupture, as well as improving the design of medical devices and clinical interventions, including surgical procedures. The book provides students, researchers, engineers, clinicians, and interventional cardiologists with an overview of the main topics related to the biomechanics of atherosclerosis, in a single volume written by several experts in the field. This volume is part of the Biomechanics of Living Organs book series. The biomechanics of human soft tissues and organs has been an emerging research field since the publication of Y.C. Fung's original book series in the 1990s. The publication of such books entirely dedicated to a specific biomechanical subject is necessary to advance scientific research in the field of biomechanics and to transfer important knowledge to future generations. Therefore, this series of volumes on the biomechanics of living organs has been created. This series began in July 2017 with the publication of a first volume on the fundamentals of Hyperelastic Constitutive Laws for Finite Element Modeling of Living Organs. The current volume on the Biomechanics of Coronary Atherosclerotic Plaque, is the latest in this new series. - Presents the main computational fluid dynamic studies performed, describing blood flow in healthy and pathological artery branches, including in coronary bifurcations - Highlights the correlation between plaque initiation regions and blood shear stress amplitude - Discusses the main biomechanical and mechanobiological models to highlight the importance of quantifying the residual and peak cap stresses and the presence of μ-calcifications to evaluate the risk of plaque rupture - Introduces the most recent intravascular imaging biomarker techniques (elastography, palpography and modulography)
Download or read book The Glossary of Prosthodontic Terms written by and published by . This book was released on 1994 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bifurcation Stenting written by Ron Waksman and published by John Wiley & Sons. This book was released on 2012-03-22 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is expert guidance on one of the most vexing clinical challenges faced by interventional cardiologists. Written by global thought leaders in the area and edited by two internationally-recognized pioneers in interventional cardiology, Bifurcation Stenting covers all techniques, imaging modalities, and devices in current use, including VH-IVUS and OCT. It includes practical tips/tricks from leading experts and a section of challenging cases to further illustrate the material and help readers better understand the treatment of bifurcation lesions.
Download or read book Transport Phenomena in Biological Systems written by George A. Truskey and published by Prentice Hall. This book was released on 2009 with total page 889 pages. Available in PDF, EPUB and Kindle. Book excerpt: For one-semester, advanced undergraduate/graduate courses in Biotransport Engineering. Presenting engineering fundamentals and biological applications in a unified way, this text provides students with the skills necessary to develop and critically analyze models of biological transport and reaction processes. It covers topics in fluid mechanics, mass transport, and biochemical interactions, with engineering concepts motivated by specific biological problems.
Download or read book Advances in Italian Mechanism Science written by Vincenzo Niola and published by Springer Nature. This book was released on 2020-08-19 with total page 902 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the proceedings of the 3rd International Conference of IFToMM ITALY, held online on September 9-11, 2020. It includes peer-reviewed papers on the latest advances in mechanism and machine science, discussing topics such as biomechanical engineering, computational kinematics, the history of mechanism and machine science, gearing and transmissions, multi-body dynamics, robotics and mechatronics, the dynamics of machinery, tribology, vibrations, rotor dynamics and vehicle dynamics. A valuable, up-to-date resource, it offers an essential overview of the subject for scientists and practitioners alike, and will inspire further investigations and research.
Download or read book Advances in Micro and Nano Manufacturing and Surface Engineering written by M. S. Shunmugam and published by Springer Nature. This book was released on 2019-11-30 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents research papers on micro and nano manufacturing and surface engineering which were presented during the 7th International and 28th All India Manufacturing Technology, Design and Research conference 2018 (AIMTDR 2018). The papers discuss the latest advances in miniature manufacturing, the machining of miniature components and features as well as improvement of surface properties. This volume will be of interest to academicians, researchers, and practicing engineers alike.
Download or read book Point of care testing written by Peter Luppa and published by Springer. This book was released on 2018-07-18 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: The underlying technology and the range of test parameters available are evolving rapidly. The primary advantage of POCT is the convenience of performing the test close to the patient and the speed at which test results can be obtained, compared to sending a sample to a laboratory and waiting for results to be returned. Thus, a series of clinical applications are possible that can shorten the time for clinical decision-making about additional testing or therapy, as delays are no longer caused by preparation of clinical samples, transport, and central laboratory analysis. Tests in a POC format can now be found for many medical disciplines including endocrinology/diabetes, cardiology, nephrology, critical care, fertility, hematology/coagulation, infectious disease and microbiology, and general health screening. Point-of-care testing (POCT) enables health care personnel to perform clinical laboratory testing near the patient. The idea of conventional and POCT laboratory services presiding within a hospital seems contradictory; yet, they are, in fact, complementary: together POCT and central laboratory are important for the optimal functioning of diagnostic processes. They complement each other, provided that a dedicated POCT coordination integrates the quality assurance of POCT into the overall quality management system of the central laboratory. The motivation of the third edition of the POCT book from Luppa/Junker, which is now also available in English, is to explore and describe clinically relevant analytical techniques, organizational concepts for application and future perspectives of POCT. From descriptions of the opportunities that POCT can provide to the limitations that clinician’s must be cautioned about, this book provides an overview of the many aspects that challenge those who choose to implement POCT. Technologies, clinical applications, networking issues and quality regulations are described as well as a survey of future technologies that are on the future horizon. The editors have spent considerable efforts to update the book in general and to highlight the latest developments, e.g., novel POCT applications of nucleic acid testing for the rapid identification of infectious agents. Of particular note is also that a cross-country comparison of POCT quality rules is being described by a team of international experts in this field.
Download or read book Cardiovascular Biomechanics written by Peter R. Hoskins and published by Springer. This book was released on 2017-02-16 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a balanced presentation of the fundamental principles of cardiovascular biomechanics research, as well as its valuable clinical applications. Pursuing an integrated approach at the interface of the life sciences, physics and engineering, it also includes extensive images to explain the concepts discussed. With a focus on explaining the underlying principles, this book examines the physiology and mechanics of circulation, mechanobiology and the biomechanics of different components of the cardiovascular system, in-vivo techniques, in-vitro techniques, and the medical applications of this research. Written for undergraduate and postgraduate students and including sample problems at the end of each chapter, this interdisciplinary text provides an essential introduction to the topic. It is also an ideal reference text for researchers and clinical practitioners, and will benefit a wide range of students and researchers including engineers, physicists, biologists and clinicians who are interested in the area of cardiovascular biomechanics.
Download or read book Cardiology Board Review written by Ramdas G. Pai and published by John Wiley & Sons. This book was released on 2023-03-10 with total page 693 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple choice question-and-answer book for cardiologists at all levels, now updated to include 100 new questions covering additional topics Cardiology Board Review, Second Edition is a multiple-choice question-and-answer study aid that is written for the primary purpose of helping candidates prepare for the American Board of Internal Medicine (ABIM) subspecialty certification. The questions address all areas of cardiology, some of which include: physical examination, ECG section with high resolution images, non-invasive and invasive imaging, myocardial diseases, and more. Each of the 1,400 questions is followed by four answers to choose from and the discussions address not only the rationale behind picking the right choice, but also fills in information around the topic so that important key concepts are clearly laid out. This helps candidates to prepare for the test, while also developing a clear understanding of various aspects of cardiology, including diagnosis and management. Written by two highly experienced authors in the field of healthcare, Cardiology Board Review, Second Edition covers topics such as: History and physical examinations, electrocardiography, chest x-rays in cardiology, stress testing and risk stratification of asymptomatic subjects, and echocardiography Cardiac magnetic resonance imaging, cardiac computed tomography, cardiac catheterization, acute coronary syndromes, and chronic coronary artery disease Heart failure, transplant, left ventricular assist devices, pulmonary hypertension, cardiomyopathies, hypertension, and diabetes mellitus Lipids, valvular heart disease, adult congenital heart disease, pericardial diseases, aortic diseases, and cardiac arrhythmias Pacemakers and defibrillators, cardiac masses, systemic disorders affecting the heart, and heart disease and pregnancy Providing comprehensive coverage of all relevant subjects and offering the easy-to-understand "why" behind the answer to each question, this second edition of Cardiology Board Review is an essential study resource for fellows in training, practicing cardiologists, and those preparing for ABIM subspecialty board in cardiology.
Download or read book Implantable Defibrillator Therapy A Clinical Guide written by Antonio Pacifico and published by Springer Science & Business Media. This book was released on 2002-08-31 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Implantable defibrillators as originally conceived by Michel Mirowski were limited to the detection and automatic termination of ventricular fibrillation. In the original "AID" device, the detection algoritlun sought to distinguish sinus rhytlun from ventricular fibrillation by identifying the "more sinusoidal waveform of ventricular fibrillation. " The therapeutic intervention was elicited only once deadly polymorphic rhythms had developed. It was rapidly learned, however, that ventricular fibrillation is usually preceded by ventricular tachycardia. Mirowski recognized the pivotal importance of developing algoritllms based on heart rate. Ventricular tachycardia detection allowed the successful development of interventions for the termination of ventricular tachyarrhythmias before they degenerated into ventricular fibrillation. Current device therapy no longer confines itself to tlle termination of chaotic rhythms but seeks to prevent them. Diagnostic algorithms moved upward along the chain of events leading to catastrophic rhytlulls. Rate smoothing algorithms were developed to prevent postextrasystolic pauses from triggering ventricular and atrial tachyarrhytlmlias. Beyond the renaissance of ectopy-centered strategies, long-term prevention received increasing attention. Multisite pacing therapies provided by "Arrhythmia Management Devices" were designed to reduce the "arrhytlunia burden" and optimize the synergy of cardiac contraction and relaxation. Clinical evidence now suggests that atrial fibrillation prevention by pacing is feasible and tllat biventricular pacing may be of benefit in selected patients with heart failure. However, these applications of device therapy that generally require ventricular defibrillation backup remain investigational and were not considered in this book.
Download or read book Medical Surgical Nursing written by Sharon Mantik Lewis and published by Mosby Incorporated. This book was released on 2003-12-01 with total page 2176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Package includes Medical-Surgical Nursing: Assessment and Management of Clinical Problems Two Volume text and Virtual Clinical Excursions 2.0
Download or read book Genetic Algorithms and Engineering Optimization written by Mitsuo Gen and published by John Wiley & Sons. This book was released on 1999-12-28 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Im Mittelpunkt dieses Buches steht eines der wichtigsten Optimierungsverfahren der industriellen Ingenieurtechnik: Mit Hilfe genetischer Algorithmen lassen sich Qualität, Design und Zuverlässigkeit von Produkten entscheidend verbessern. Das Verfahren beruht auf der Wahrscheinlichkeitstheorie und lehnt sich an die Prinzipien der biologischen Vererbung an: Die Eigenschaften des Produkts werden, unter Beachtung der äußeren Randbedingungen, schrittweise optimiert. Ein hochaktueller Band international anerkannter Autoren. (03/00)
Download or read book Advances in Biomedical Engineering written by Pascal Verdonck and published by Elsevier. This book was released on 2008-09-11 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this essential reference is to bring together the interdisciplinary areas of biomedical engineering education. Contributors review the latest advances in biomedical engineering research through an educational perspective, making the book useful for students and professionals alike. Topics range from biosignal analysis and nanotechnology to biophotonics and cardiovascular medical devices. - Provides an educational review of recent advances - Focuses on biomedical high technology - Features contributions from leaders in the field
Download or read book Principles of Biomedical Engineering Second Edition written by Sundararajan Madihally and published by Artech House. This book was released on 2019-12-31 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated edition of an Artech House classic introduces readers to the importance of engineering in medicine. Bioelectrical phenomena, principles of mass and momentum transport to the analysis of physiological systems, the importance of mechanical analysis in biological tissues/ organs and biomaterial selection are discussed in detail. Readers learn about the concepts of using living cells in various therapeutics and diagnostics, compartmental modeling, and biomedical instrumentation. The book explores fluid mechanics, strength of materials, statics and dynamics, basic thermodynamics, electrical circuits, and material science. A significant number of numerical problems have been generated using data from recent literature and are given as examples as well as exercise problems. These problems provide an opportunity for comprehensive understanding of the basic concepts, cutting edge technologies and emerging challenges. Describing the role of engineering in medicine today, this comprehensive volume covers a wide range of the most important topics in this burgeoning field. Moreover, you find a thorough treatment of the concept of using living cells in various therapeutics and diagnostics. Structured as a complete text for students with some engineering background, the book also makes a valuable reference for professionals new to the bioengineering field. This authoritative textbook features numerous exercises and problems in each chapter to help ensure a solid understanding of the material.
