Download or read book Serological Cancer Markers written by Stewart Sell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book-the fourth volume of a series on Can cer Markers-is intended to provide an updated "status report" on today's use of cancer markers in the diagnosis and monitoring of can cer, with an emphasis on cancer markers detected in the serum. It has been 7 years since the publication of the last volume in this series. The 1980, 1982, and 1985 volumes covered the development of cancer markers, not only in their roles of unraveling the basic biology of can cer, but also as increasingly important players in the management of patients with cancer. During the last 7 years we have seen the applica tion of a number of markers identified by monoclonal antibodies, as well as the beginnings of the use of genetic markers defined by mo lecular probes. Measurements of oncogenes in tissues or cells prom ise many applications for the future, but as yet, these genes have not shown to be useful as serum markers of cancer. The commercial interest in serum markers for cancer, particu larly for the diagnosis and monitoring of tumor patients, is indicated in Chapter 24 by Owen, where the total worldwide market for cancer markers is projected to increase from $148 million in 1988 to $232 million in 1993. The degree of research interest in cancer markers is reflected in the fact that in 1988 a separate category for tumor mark ers was added to Index Medicus.

Download or read book Serological Tumour Markers written by J. E. Roulston and published by . This book was released on 1993 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gives an overview of the current status, potential and clinical application of one of the latest techniques in cancer screening. The authors outline the principles and practice of serological tumour markers and provide a concise context for their application.

Download or read book Histological and Serological Tumor Markers and Gene Expression and Their Clinical Usefulness in Cancers written by Dan Hellberg and published by Nova Science Publishers. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The number of commercially available antibodies for the detection of biological markers, tumor markers, by immunohistochemistry or serological methods in cancer are rapidly increasing. Results in different studies are often contradictory and the usefulness of single tumor markers in different cancer types is unclear. An increasing number of studies on genetic "fingerprints" are being reported. This book represents the most comprehensive and up-to-date publication on histological and serological tumor markers, also commenting recent genetic studies. Sixteen major cancer types and an additional chapter on HIV-related cancers are reviewed by more than 40 authors. These are cancer of the breast, lung, esophagus, stomach, pancreas, liver, colon, rectum, anus, skin, brain, prostate, penis, ovary, uterus, uterine cervix and HIV-related cancers. The authors are active and respected researchers, experts in their fields. Tumor markers will be evaluated for clinical usefulness in diagnostics, prognosis and therapy. Definitive present usefulness is given for the specific cancer types and their purpose of use. Tumor markers that are still being evaluated but of possible future clinical importance are discussed. The index will make it easy to find a particular tumor marker and compare studies on different cancer types. The book is meant to inspire clinical and laboratory management as well as planning research and evaluation of results. Thus, oncologists, pathologists and other physicians who are involved in patients with cancer will find it useful.

Download or read book Serological Tumor Markers for Monitoring Breast Cancer written by György Sölétormos and published by . This book was released on 2001 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biomarkers in Cancer written by Victor R. Preedy and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Human Cancer Markers written by Stewart Sell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to diagnose cancer by simple measurement of a serum or tissue' 'marker" has been a goal of medical science for many years. There is ample evidence that tumor cells are different from normal cells and pro duce substances that can be detected by currently available immuno chemical or biochemical methods. These "cancer markers" may be se creted proteins, enzymes, hormones, fetal serum components, monoclonal immunoglobulins, cell surface components, or cytoplasmic constituents. The purpose of this book is to present the current status of our knowledge of such cancer markers. The first tumor marker identified by laboratory means was Bence Jones protein. In a series of lectures delivered to the Royal College of Phy sicians in London in 1846, Dr. H. Bence Jones described studies on a urine sample sent to him with the following note: "Dear Dr. Jones-The tube contains urine of very high specific gravity. When boiled it becomes slightly opaque . . . . etc. " Dr. Jones found that heating of the urine after addition of nitric acid resulted in formation of a heavy precipitate; acid ad dition may have been required to bring the urine to pH 4-6 at which Bence Jones proteins are more likely to precipitate when heated. This urinary pre cipitate was associated with a bone disease termed "mollities ossium. " [H. Bence Jones, Papers on Chemical Pathology, Lecture III. Lancet 2, 269-274 (1847)].

Download or read book Cancer Diagnostics written by Robert M. Nakamura and published by Springer Science & Business Media. This book was released on 2004-07-16 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews recent and emerging clinical laboratory tests that can help in the early detection, evaluation, and prediction of human tumors. Emphasizing the importance of molecular and genetic RNA/DNA tets that detect persons at high risk for specific cancers, the authors explore these novel serological assays, cellular assays useful for anatomic pathology, and molecular and genetic assays.

Download or read book Tumor Marker Protocols written by Margaret Hanausek and published by Springer Science & Business Media. This book was released on 1998-03-09 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: A much-needed collection of cutting-edge methods for the detection and discovery of new cancer markers, particularly molecular tumor markers. Each method is fully described by a hands-on expert who regularly uses it in the laboratory and has perfected it to a high degree of ready reproducibility. Special emphasis is given to statistical considerations in the analysis of tumor markers, recent discoveries in the field of serum and tissue marker proteins, cytogenetic markers, molecular markers, and markers for the early detection of cancer. The well-honed procedures detailed here will enable cancer researchers and clinical oncologists alike to realize the promise of these powerful new diagnostic strategies for the detection, therapy, and successful prevention of cancer.

Download or read book Tumor Markers Research Perspective written by Geoffrey A. Sinise and published by Nova Publishers. This book was released on 2007 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumour markers are molecules occurring in blood or tissue that are associated with cancer, and whose measurement or identification is useful in patient diagnosis or clinical management. This book analyses potential signals of cancerous tumours, otherwise known as markers or indicators. This includes, direct and rapid determination of cancer antigen, potential tumour markers for cholangiocarcinoma, melanoma inhibitory activity, metastatic uveal melanoma, measurement of tumour oxygenation, bladder cancer markers, epithelial cell adhesion and progression markers in prostate tumours.

Download or read book Tumor Markers written by Janis V. Klavins and published by . This book was released on 1985 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book TNM Atlas written by Bernd Spiessl and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Confronted with a myriad ofT's, N's and M's in the VICC TNM booklet, classifying a malignancy may seem to many cancer clini cians a tedious, dull and pedantic task. But at a closer look at the TNM Atlas all of a sudden lifeless categories become vivid im ages, challenging the clinician's know-how and investigational skills. Brigit van der Werf-Messing, M.D. Professor of Radiology Past Chairman of the International TNM-Committee of the VICC Rotterdam, July 1982 Preface In 1938 the League of Nations Health Organization published an Atlas Illustrating the Division of Cancer of the Uterine Cervix into Four Stages (J. Heyman, ed., Stockholm). Since this work appeared, the idea of visual representation of the anatomical ex tent of malignant tumours at the different stages of their develop ment has been repeatedly discussed. At its meeting in Copenhagen in July 1954, the DICC adopted as part of its programme "the realization of a clinical atlas". How ever, the time to do the planned book of illustrations was not ripe until the national committees and international organizations had officially recognized the 28 classifications of malignant tu mours at various sites as presented in the third edition of the TNM Booklet edited by M. Harmer (TNM Classification of Malig nant Tumours, 1978). This was all the more important since publi cation of the Booklet was followed in 1980 by publication of a Brochure of Checklists, edited by A.H.

Download or read book Tumor Markers written by Eleftherios P. Diamandis and published by Amer. Assoc. for Clinical Chemistry. This book was released on 2002 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cancer Biomarkers in Body Fluids written by Gabriel D. Dakubo and published by Springer Nature. This book was released on 2019-08-29 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to measure and monitor cancer biomarkers in “body fluid biopsy” should greatly impact oncologic practice. “Biomarkers in Proximal Fluids”, the third of the “Cancer Biomarkers in Body Fluids” series details cancer signatures in none or minimally circulating body fluids including saliva, sputum, bronchoalveolar lavage fluid, exhaled breath condensate, nipple aspirate fluid, gastric and pancreatic juice, stool, urine, and prostatic, peritoneal and cerebrospinal fluid. These fluids are enriched with biomarkers, especially those emanating from cells of the proximal tissue. Chapter 1 examines the global burden of cancer and the need for regional efforts at primary prevention, early detection and patient care. Chapters 2-12 address tissue-specific biomarkers in associated body fluids. The tumor interstitial fluid as a microenvironment rich in cancer biomarkers is detailed in chapter 13, while chapter 14 looks at the human body fluid microbiome and its evolving role in cancer. Commercially available assays using proximal fluids are examined at the end of the respective chapters. This book complements its predecessors and is equally useful to oncologists, cancer researchers, clinicians, medical students, nurses, diagnostic laboratory and pharmaceutical industry personnel.

Download or read book Cancer Markers written by Stewart Sell and published by Springer Science & Business Media. This book was released on 1980-01-31 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text contains an account of the progress that has been made in this field, and should serve not only as a useful reference, but also as a stimulus for the development of new biochemical and clinical approaches to cancer diagnosis and treatment.

Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Download or read book Circulating Tumor Markers of the New Millennium written by James T. Wu and published by Amer. Assoc. for Clinical Chemistry. This book was released on 2002 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hope is that by measuring soluble, circulating markers, targets for cancer therapy can be identified with non-invasive procedures. To help attain that goal, Wu (pathology, U. of Utah-Salt Lake City) identifies and describes any circulating tumor markers he thinks might help. Annotation copyrighted by Book News, Inc., Portland, OR

Download or read book Textbook of Oral Cancer written by Saman Warnakulasuriya and published by Springer Nature. This book was released on 2020-02-22 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive multidisciplinary book examines all aspects of cancers of the mouth and oropharynx with the aim of equipping advanced students and practitioners in the early stages of specialist training with an up-to-date guide and reference. A multinational team of authors – all experts in the field of oral oncology – provide illuminating contributions on the full range of relevant topics: epidemiology, risk factors, clinical features, staging and prognostic factors, pathology, diagnostic techniques, disease prevention, surgery, radiotherapy, and chemotherapy. Molecular biology, molecular targeted therapies for advanced cases, and future diagnostic and prognostic applications of new technologies also receive careful attention. In providing a wealth of essential information and guidance in a practical format, the book will be a superb asset for senior graduate students in dentistry and specialist trainees in head and neck oncology. It will also be of high value for the many physicians, surgeons, pathologists, dentists, and specialists involved in the prevention, diagnosis, and management of squamous cell carcinomas of the oral cavity and oropharynx.