Download or read book Serologic Studies of the Soluble Antigens of the Pathogenic Clostridia written by Stanley Sumner Green and published by . This book was released on 1963 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Serological Studies of the Soluble Antigens of Clostridium Perfrigens Types A F by Agar Gel Diffusion written by Carolyn Doreen Bohan and published by . This book was released on 1961 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Serology of the Soluble Antigens of Clostridium Chauvoei written by Ted Taylor Odle and published by . This book was released on 1964 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: Members of the genus Clostridium synthesize and secrete many antigenic substances into the nutrient medium in which the microorganisms have been cultivated. The study of the antigenic nature of these enzymes and/or exotoxings is important because the organisms of this genus which cause gas gangrene are extremely pathogenic and their taxonomic position can cause confusion at the time of a clinical diagnosis of the disease. A rapid serological method was described for differentiating two similar pathogens; i.e., Clostridium chauvoei and Clostridium septicum. Antisera were prepared against five strains of Cl. chauvoei, two strains of Cl. novyi type B, and five strains of Cl. septicum. Rabbits were used as the experimental animals for production of hyperimmune serum. Geinea pigs, as a source of antiserum specific for Cl. chauvoei, proved to be unsatisfactory. The bacterins for these immunizations were derived from Clostridium cultures grown by both conventional and cellophane sac techniques. Formaldehyde was used for inactivation of the cells and toxin and the bacterins were alum precipitated. Various immunization schedules were tested to find one advantageous for demonstration of antigenic similarity. The results obtained by antigenic analysis with the double immunodiffusion technique are reported. Using the hyperimmuned and commercial antiserum, the following reactions occurred between Cl. chauvoei and other species: There are at least four antigenic supstances produced by Cl. chauvoei that are precipitated by Cl. septicum antisera and vice versa. The antisera prepared against Cl. novyi type B reacted with Cl. chauvoei antigen without the production of lines of identity. Cl. chauvoei antisera and Cl. novyi types B and D antigen precipitatied as a dense zone around the well containing antiserum. The use of the cellophane sac technique is described in preparation of the antigen for both immunization and immunodiffusion. This technique has been used to concentrate the bacterial cells and their soluble products. This was accomplished by growing the microorganisms inside a cellophane sac that was suspended into a specially developed medium. The small diameter of the pores in the membrane prevents diffusion of molecules large enough to be antigenic. Therefore, the final antigen preparation was free of antigenic medium contituents. The microorganisms used for inoculation are grown in liquid media, centerfuged, and the packed cells constitute the inoculum deleting the major portion of the seed media antigens from the cellophane sac. The application of the results obtained from the immunodiffusion analyses aids in clinical diagnosis of the disease producing agents of blackleg and malignant edema. When antisera are available, a serological differentiation can be made based on immunodiffusion patterns obtained with homologous and/or heterologous antisera. This can be accomplished in forty-eight hours by inoculating a guinea pig with a sample from the infected bovine, inoculating a tube of nutrient medium with a piece of the dead guinea pig's liver, and inoculating the media and redording where the lines of precipitation develop.
Download or read book Virology E Book written by Stephen N J Korsman and published by Elsevier Health Sciences. This book was released on 2012-08-17 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a concise, highly accessible introduction to medical virology, incorporating essential basic principles as well as a systematic review of viruses and viral diseases. It pays particular attention to developments in anti-viral therapy that are becoming increasingly effective in modern medicine. It is an ideal textbook for the information-overloaded student and an invaluable everyday companion for the busy professional who needs a good understanding of the current state of medical virology. In keeping with the highly successful format of other Illustrated Colour Texts, it presents the subject as a series of succinct 2 page ‘learning units’, using a superb collection of clear illustrations and clinical photographs, concise yet comprehensive text and key point boxes to aid quick access to information and examination preparation. So whether you are a medical student, junior doctor, medical scientist, trainee in infectious diseases or student on another allied medical course, this book is here to make your life easier! It will also provide a very solid foundation for any who plan to delve deeper into this fascinating field. Part of the popular Illustrated Colour Text series Information presented in double page spreads for easy learning Highly illustrated with both full colour graphics and clinical photographs Each spread includes a key point box for exam preparation
Download or read book Analytical Serology of Microorganisms written by George Kwapinski and published by New York : Interscience Publishers. This book was released on 1969 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1960 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clostridia of Wound Infection written by Allan Trevor Willis and published by . This book was released on 1969 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Laboratory Methods in Anaerobic Bacteriology written by V. R. Dowell and published by . This book was released on 1974 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Current Bibliography of Epidemiology written by and published by . This book was released on 1972 with total page 1302 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Journal of Bacteriology written by Charles-Edward Amory Winslow and published by . This book was released on 1968 with total page 1382 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Addressing Emerging Infectious Disease Threats written by and published by . This book was released on 1994 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: This plan addresses the need to improve our ability to identify infectious disease threats and respond to them effectively by improving the public health infrastructure at the local, state and federal levels. The goals of the plan are surveillance (detect, promptly investigate, and monitor emerging pathogens, the diseases they cause, and the factors influencing their emergence); applied research (integrate laboratory science and epidemiology to optimize public health practice); prevention and control (enhance communication of public health information about emerging diseases and ensure prompt implementation of prevention strategies); and infrastructure (strengthen local, state, and federal public health infrastructures to support surveillance and implement prevention and control programs).
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1988 with total page 1418 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1961 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Pathogenic Anaerobic Bacteria written by Louis De Spain Smith and published by Charles C. Thomas Publisher. This book was released on 1984 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Janeway s Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Download or read book Clostridia written by Nigel P. Minton and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: To the uninitiated, the genus Clostridium is likely more to be associated with disease than biotechnology. In this volume, we have sought to remedy this misconception by compiling aseries of chapters which, together, provide a practically-oriented handbook of the biotechnologie potential of the genus. Clostridium is a broad grouping of organisms that together undertake a myriad of biocatalytic reactions. In the first two chapters, the reader is introduced to this diversity, both taxonomically and physiologically. In the following chapter, the current state of genetic analysis of members of the genus is reviewed. The remaining chapters concentrate on specific, exploit able aspects of individual Clostridium species-highlighting their range of unique capabilities (of potential or recognized industrial value), particu larly in the areas of biotransformation, enzymology, and the production of chemical fuels. Fittingly, the final chapter demonstrates that even the most toxic of the clostridia can be of therapeutic value. The contributors to this volume reflect the trans national interest in Clostridium, and we are indebted to each of them for making this volume possible. We particularly wish to acknowledge the contributions, both to this volume and to microbiology in general, of Dr. Elizabeth Cato, who, sadly, died shortly be fore publication ofthis volume. Finally, we would like to join the authors in recommending closer and wider consideration of the attributes and capabilities of this genus.
Download or read book Molecular Biology and Pathogenicity of Mycoplasmas written by Shmuel Razin and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: was the result of the efforts of Robert Cleverdon. The rapidly developing discipline of molecular biology and the rapidly expanding knowledge of the PPLO were brought together at this meeting. In addition to the PPLO specialists, the conference invited Julius Marmur to compare PPLO DNA to DNA of other organisms; David Garfinkel, who was one of the first to develop computer models of metabolism; Cyrus Levinthal to talk about coding; and Henry Quastler to discuss information theory constraints on very small cells. The conference was an announcement of the role of PPLO in the fundamental understanding of molecular biology. Looking back 40-some years to the Connecticut meeting, it was a rather bold enterprise. The meeting was international and inter-disciplinary and began a series of important collaborations with influences resonating down to the present. If I may be allowed a personal remark, it was where I first met Shmuel Razin, who has been a leading figure in the emerging mycoplasma research and a good friend. This present volume is in some ways the fulfillment of the promise of that early meeting. It is an example of the collaborative work of scientists in building an understanding of fundamental aspects of biology.
