Download or read book Senescence written by Jolanta Dorszewska and published by BoD – Books on Demand. This book was released on 2017-08-30 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the second half of the twentieth century, life expectancy was prolonged, and the number of elderly people increased. The effect of population aging increases in the frequency of neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, epilepsy, and stroke. Also, a higher incidence of infections, autoimmune diseases, and malignant cancers is observed in elderly people. The aging process is difficult to define. Are physiological changes in elderly people controlled by specific genes? Is aging process a pathophysiology affecting different organs with different severity? Finding answers to these questions may help prevent age-related diseases and improve the quality of life of old people. This book was made as a compendium on contemporary challenges in senescence.
Download or read book Senescence Physiology Or Pathology written by and published by . This book was released on 19?? with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Physiology and Pathology of Human Aging written by Ralph Goldman and published by . This book was released on 1975 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Old Age the Major Involution written by Aldred Scott Warthin and published by . This book was released on 1930 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cellular Senescence in Disease written by Manuel Serrano and published by Academic Press. This book was released on 2021-11-27 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the 2023 PROSE award in Biomedicine and Neuroscience! Research in the field of senescence has boomed recently due to the gradual realization that senescent cells are associated with a significant number of diseases. The genetic or pharmacological elimination of senescent cells can cause widespread benefits and improves outcomes for most of those diseases. Cellular Senescence in Diseases presents an updated review of the role of cellular senescence in multiple pathologies. Focus is given to those diseases where the implication of senescence has been more extensively documented, such as (cancer, lung and liver diseases, diabetes, Neurodegenerative diseases and others). The Editors recruited a group of worldwide experts in each individual pathology to review the role of cellular senescence in each one of them, aiming at identifying potential therapeutic pathways. The first two chapters provide an overview of the cellular senescence principles. Next, the chapters are divided into specific diseases. Cancer, including premalignant lesions (OIS), Advanced disease (TIS), and Metastasis are covered. The following condition covered is Lund diseases, including IPF, COPD, and Pulmonary Hypertension. Next Liver Diseases are covered, including Fibrosis and Cirrhosis, and Fatty liver disease. Next there is coverage for Kidney implications, including fibrosis and transplantation. Vascular diseases are covered next including infarction and hear fibrosis, and atherosclerosis. Both diabetes types 1 and 2 are covered next. Following chapters cover Obesity, Sarcopenia, and Bone and Cartilage disorders, respectively. Neurodegenerative diseases are covered next, focusing on Alzheimer and Parkinson. The next chapter discusses accumulation of senescent cell in tissues during aging. The two final chapters cover current developments and conclusions. Cellular Senescence in Diseases is designed for researchers and clinicians with a focus on the cellular mechanisms of diseases. All chapters cover current experimental therapeutic approaches to eliminate or cancel the pathological effects of senescent cells. Pharmaceutical scientists may also benefit from the contents of the book in the exploration of novel therapeutic opportunities. - 2023 PROSE Awards - Winner: Category: Biomedicine and Neuroscience: Association of American Publishers - Provides a thorough introduction to Cellular Senescence - Covers all major pathologies for which cellular senescence has shown evidence of involvement - Focuses on possible therapeutic pathways - Edited and authored by worldwide experts
Download or read book Old Age written by Aldred Scott Warthin and published by . This book was released on 1929 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Old Age the Major Involution written by Aldred Scott 1866-1931 N 7 Warthin and published by Hassell Street Press. This book was released on 2021-09-10 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Download or read book Geriatric Gastroenterology written by C. S. Pitchumoni and published by Springer Science & Business Media. This book was released on 2012-07-26 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults.
Download or read book Aging written by L. Robert and published by Karger Medical and Scientific Publishers. This book was released on 2014-05-16 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging inspired a large number of theories trying to rationalize the aging process common to all living beings. In this publication the most important environmental and intrinsic mechanisms involved in the aging process and in its pathological consequences are reviewed. Furthermore theoretical and experimental evidence of the most important theoretical elements based on Darwinian evolution, cellular aging, role of cell membranes, free radicals and oxidative processes, receptor-mediated reactions, the extracellular matrix and immune functions as well as the most important environmental and intrinsic mechanisms involved in the aging process and in its pathological consequences are discussed. These presentations of theories and related experimental facts give a global overview of up to date concepts of the biology of the aging process and are of essential reading not only for specialists in this field but also for practitioners of scientific, medical, social and experimental sciences.
Download or read book Old Age written by Alfred Scott Warthin and published by . This book was released on 1930 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Geriatric Forensic Medicine and Pathology written by Kim A. Collins and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers all facets of geriatric forensic medicine and pathology, from natural changes, trauma and dementias, to toxicology and scene investigation.
Download or read book The Aging Cardiovascular System written by Vladimir Veniaminovich Frolʹkis and published by . This book was released on 1996 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Physiological Basis of Aging and Geriatrics written by Paola S. Timiras and published by CRC Press. This book was released on 1994-09-16 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging is an inevitable aspect of living. This book covers the aging process from a physiological viewpoint, examining all systems of the body and describing changes that occur with normal aging and in disease. Its primary focus is on humans, but some animal and in vitro research is included to explain mechanisms and theories of aging. Integrated aspects of aging (e.g., demography of aging) are considered, and preventive and interventive measures (pharmacology, diet, exercise) for ensuring healthful aging are discussed. The Second Edition of Physiological Basis of Aging and Geriatrics considers many new approaches and methods for studying the aging process. New and updated information on molecular and cellular mechanisms, pathology, and aging-related diseases is provided to promote a better understanding of basic biological mechanisms. Theories, epidemiology, demographics, and comparative and differential aging are also presented.
Download or read book Geriatric Psychiatry written by Ana Hategan and published by Springer. This book was released on 2018-04-03 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook presents real-world cases and discussions that introduce the various mental health syndromes found in the aging population before delving into the core concepts covered by geriatric psychiatry curricula. The text follows each case study with the vital information necessary for physicians in training, including key features of each disorder and its presentation, practical guidelines for diagnosis and treatment, clinical pearls, and other devices that are essential to students of geriatric psychiatry. With the latest DSM-5 guidelines and with rich learning tools that include key points, review questions, tables, and illustrations, this text is the only resource that is specifically designed to train both American and Canadian candidates for specialty and subspecialty certification or recertification in geriatric psychiatry. It will also appeal to audiences worldwide as a state-of-the-art resource for credentialing and/or practice guidance. The text meets the needs of the future head on with its straightforward coverage of the most frequently encountered challenges, including neuropsychiatric syndromes, psychopharmacology, eldercare and the law, substance misuse, mental health following a physical condition, medical psychiatry, and palliative care. Written by experts in the field, Geriatric Psychiatry: A Case-Based Textbook is the ultimate resource for graduate and undergraduate medical students and certificate candidates providing mental health care for aging adults, including psychiatrists, psychologists, geriatricians, primary care and family practice doctors, neurologists, social workers, nurses, and others.
Download or read book Aging and Age Related Disorders written by Stephen Bondy and published by Humana Press. This book was released on 2010-09-08 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Features that characterize the aging process include the gradual accumulation of cell damage after prolonged exposure to oxidative and inflammatory events over a lifetime. In addition to the accretion of lesions, the intrinsic levels of pro-oxidant and aberrant immune responses are elevated with age. These adverse events are often further enhanced by the chronic and slow progressing diseases that characterize the senescent brain and cardiovascular system. The incidence of some disorders such as Alzheimer's disease and vascular diseases are sufficiently prevalent in the extreme elderly that these disorders can arguably be considered "normal". Aging and Aging-Related Disorders examines the interface between normal and pathological aging, and illustrates how this border can sometimes be diffuse. It explores and illustrates the processes underlying the means by which aging becomes increasingly associated with inappropriate levels of free radical activity and how this can serve as a platform for the progression of age-related diseases. The book provides chapters that examine the interactive relationship between systems in the body that can enhance or sometimes even limit cellular longevity. In addition, specific redox mechanisms in cells are discussed. Another important aspect for aging discussed here is the close relationship between the systems of the body and exposure to environmental influences of oxidative stress that can affect both cellular senescence and a cell’s nuclear DNA. What may be even more interesting to note is that these external stressors are not simply confined to illnesses usually associated with aging, but can be evident in maturing and young individuals. A broad range of internationally recognized experts have contributed to this book. Their aim is to successfully highlight emerging knowledge and therapy for the understanding of the basis and development of aging–related disorders.
Download or read book The Biology of Senescence written by Alex Comfort and published by CreateSpace. This book was released on 2010-11-25 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biology of Senescence
Download or read book Endocrinology of Aging written by Emiliano Corpas and published by Elsevier. This book was released on 2020-09-22 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrinology of Aging: Clinical Aspects in Diagrams and Images presents chapters in a way that allows the reader to incorporate concepts and complex facts in a visual way. As the global population becomes older, the need for a deeper understanding of geriatric pathology increases, and with it, there becomes a greater need to access educational resources on the endocrinology and metabolism of aging. According to the United Nations, the number of people aged 60 years or over in the world is projected to be 1.4 billion in 2030 and 2.1 billion in 2050, hence this is a timely resource. Divided according to specific endocrine and metabolic systems, providing evidence-based content Addresses physiological changes that alter the pathophysiology of the clinical picture Considers the patient transitioning from young adult to elderly, discussing endocrinological challenges to discern physiology from pathology Focuses on age as an essential factor for diagnostic and endocrine management
