Download or read book Senescence Back and Forth written by Urs Nydegger and published by Springer Nature. This book was released on 2023-06-10 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about lifelong ageing of humans. The basic biochemical and genetic mechanisms remain ill known, and differ among individuals. The book starts out to explore the plant and animal kingdoms to answer questions human ageing needs for understanding. First, we come to scrutinize time running out and what ‘normal’ means with impacts on the genome and on protein half- lives and function. Ageing goes beyond biochemical skid treated by geroprotector drugs, including biosimilars; albeit early diagnosis with standard medical laboratory assays, here addressed, sheds light with focus on basic research. Modern tools, including machine learning, and DNA technology, e.g. genomics, have already provided for unanticipated insights. The chapters then turn around senescence of the entire organism based on variable ageing of single organs embedded in neuronal networks . Psychological stress factors, dementia opposed to vigilance, and distinction of ageing from overt disease are contrasting in humans and are opposed in the book. Senescence, seen as a one way track may be reverted into rejuvenation, made possible by insights into immunosenescence and genomic approaches. Risk management in health insurance finds important clues in this book. The topics addressed between the book covers help to understand the trend to the ever- prolonging life expectancy beyond the centenarian age group; nursing care takers and pharmaceutical industry are invited to understand what’ is going on in senior people to make their geriatric population remain fit or become frail.
Download or read book The Biology of Senescence written by Bernard Swynghedauw and published by . This book was released on 2019 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the fundamental process of senescence, and reviews a new concept developed by a number of research groups that is based on cellular senescence and its secretome. This concept provides a basic explanation of the main physiological and pathological features of senescence, and delineates possibilities for "treating" it. Following an introduction to the emerging medical landscape, the increasing incidence of a new epidemiological group (age-related "chronic non-transmissible diseases"), and the multiple origins of aging, the book explores and characterizes the senescent cell, which is linked to benign and pathological age-related manifestations. In turn, the closing chapters discuss how to "treat" or "prevent" the aging process, underscoring the central role of physical exercise and caloric reduction as compared to new senolytic approaches. Appendices are also provided, and address circadian rhythms, telomere shortening, diabetic cardiomyopathy, and senescence in plants and bacteria. Given its scope, the book will primarily be of interest to geriatricians, but will also appeal to a wider range of clinicians.
Download or read book Senescence written by G. Stanley Hall and published by . This book was released on 2015-07-09 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Excerpt from Senescence: The Last Half of Life In this book I have tried to present the subjects of Old Age and Death from as many viewpoints as possible in order to show how the ignorant and the learned, the child, the adult, and the old, savage and civilized man, pagans and Christians, the ancient and the modern world, the representatives of various sciences, and different individuals have viewed these problems, letting each class, so far as I could, speak for itself. This part of the task has been long and arduous and my conspectus is not entirely encyclopedic, as it set out to be. I have also tried to develop an idea of death, and especially of old age, which I believe to be, if not essentially new, more true to the facts of life and mind than those now current, and which I think much needed by the world just now. Despite the great and growing interest that has impelled this study, its themes have proved increasingly depressing, so that its conclusion brings a unique relief that I may now turn to more cheerful occupations, although it would be craven to plead this as an extenuation of the shortcomings of which I am increasingly conscious. If I have at certain points drawn too frankly upon my own personal experiences with age I realize that this does not compensate for my limitations in some of the special fields I ventured to enter. I have had in mind throughout chiefly the nature and needs of intelligent people passing or past middle life quite as much as of those actually entering old age. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
Download or read book Senescence Senotherapeutics and Mitochondria written by and published by Elsevier. This book was released on 2023-07-14 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Senescence, Senotherapeutics and Mitochondria, Volume 136 offers updates on this unique topics, with chapters covering Cellular Senescence in Aging: Molecular Basis, Implications and Therapeutic Interventions, Mitochondria-associated Cellular Senescence Mechanisms: Biochemical and Pharmacological Perspectives, Mitochondria in cell senescence: Friend or Foe?, The role of mitochondria and mitophagy in cell senescence, Small molecules targeting mitochondrial dysfunction for potential senotheraputics, Senolytic and senomorphic interventions to defy senescence-associated mitochondrial dysfunction, Mitochondrial targeting peptides and probes, Mitochondria-derived peptides in healthy ageing and therapy of age-related diseases, and much more. Other sections cover Targeting of mitostasis-proteostasis axis by antioxidant polysaccharides in neurodegeneration, Phytotherapeutic targeting of the mitochondria in neurodegenerative disorders, Melatonin as mitochondria-targeted drugs, Coenzyme Q-related compounds to maintain healthy mitochondria during aging, Changing ROS, NAD and AMP: a path to longevity via mitochondrial therapeutics, and more. - Updates on how mitochondria are closely related to the survival of senescent cells using either mitochondria-targeted senolytic or redox modulator senomorphic strategies - Differentiates itself from other books with its multidisciplinary perspectives and multidimensional clinical approaches - Offers a novel perspective on both the basic and clinical sciences for a wide group of well-established academicians, students and researchers in medicinal chemistry, gerontology, geriatrics, oncology, pharmacology, pathology, bioinformatics, sports science and nutritional sciences
Download or read book Senescence and Senescence Related Disorders written by Wang Zhiwei and published by BoD – Books on Demand. This book was released on 2013-02-20 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Senescence is a biological process that causes a progressive deterioration of structure and function of all organs chronologically. Recent studies have revealed the detailed molecular mechanisms of senescence using cell culture system and experimental organisms. It is thought that senescence is a potential cause for the development of various age-related disorders such as cancer, cardiovascular and neurodegenerative disorders. This book discusses in detail senescence and its related diseases by distinguished researchers and practicing clinicians. The cumulative knowledge from the studies could lead to developing new approaches for anti-senescence interventions.
Download or read book Senescence in Plants written by Brandon Chesser and published by . This book was released on 2015-01-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the phenomena related to ageing in plants. It covers various aspects relating to ageing and discusses the factors associated with it. It provides elucidative information regarding ageing processes and senescent changes that living creatures such as plants face. Renowned experts and researchers in the field of senescence have made their valuable contributions to this book. It aims to benefit students and researchers interested in this field.
Download or read book Hemodynamics written by Aise Seda Artis and published by BoD – Books on Demand. This book was released on 2012-04-25 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemodynamics is study of the mechanical and physiologic properties controlling blood pressure and flow through the body. The factors influencing hemodynamics are complex and extensive. In addition to systemic hemodynamic alterations, microvascular alterations are frequently observed in critically ill patients. The book "Hemodynamics: New Diagnostic and Therapeuric Approaches" is formed to present the up-to-date research under the scope of hemodynamics by scientists from different backgrounds.
Download or read book Merchants of Immortality written by Stephen S. Hall and published by HMH. This book was released on 2003-06-18 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Discover Best Science Book of the Year: “A fascinating, accurate and accessible account of some of [the] contemporary efforts to combat aging” (The New York Times). Los Angeles Times Book Prize Finalist Named a Best Book of the Year by the New York Times, San Jose Mercury News, and Library Journal An award-winning writer explores science’s boldest frontier—extension of the human life span—interviewing dozens of people involved in the quest to allow us to live longer, better lives. Delving into topics from cancer to stem cells to cloning, Merchants of Immortality looks at humankind’s quest for longevity and tackles profound questions about our hopes for defeating health problems like heart attacks, Parkinson’s disease, and diabetes. The story follows a close-knit but fractious band of scientists as well as entrepreneurs who work in the shadowy area between profit and the public good. The author tracks the science of aging back to the iconoclastic Leonard Hayflick—who was the first to show that cells age, and whose epic legal battles with the federal government cleared the path for today’s biotech visionaries. Among those is the charismatic Michael West, a former creationist who founded the first biotech company devoted to aging research. West has won both ardent admirers and committed foes in his relentless quest to promote stem cells, therapeutic cloning, and other technologies of “practical immortality.” Merchants of Immortality breathes scintillating life into the most momentous science of our day, assesses the political and bioethical controversies it has spawned, and explores its potentially dramatic effect on the length and quality of our lives. “Timely and engrossing . . . This is top-drawer journalism.” —Publishers Weekly, starred review “A carefully documented examination of how society deals with life-and-death matters.” —Kirkus Reviews, starred review “An important survey of the entire landscape of the science aimed at extending human life.” —Newsday “[This] highly readable and important book . . . provide[s] new insights into the intersection of science and politics.” —The Washington Post
Download or read book International Handbook of Population Aging written by Peter Uhlenberg and published by Springer Science & Business Media. This book was released on 2009-04-29 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Handbook of Population Aging examines research on a wide array of the profound implications of population aging. It demonstrates how the world is changing through population aging, and how demography is changing in response to it.
Download or read book The Ecological Farm written by Helen Atthowe and published by Chelsea Green Publishing. This book was released on with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: The breakthrough resource for fruit and vegetable growers at every scale who want to go “beyond organic” and build higher soil quality and fertility using fewer inputs through a unique ecosystem-balancing approach. The Ecological Farm is the go-to guide for ecological growing, with a unique focus on reduced tillage, minimizing farm and garden inputs, and pest control. Reflecting the wisdom that farmer, consultant, and educator Helen Atthowe and her late husband, Carl Rosato, gained during decades of farming experience, this book guides readers on how to reduce or eliminate the use of outside inputs of fertilizer or pesticides—even those that are commonly used on certified organic orchards and market gardens. In clear language and with color photographs, charts, and graphs throughout, the book emphasizes the importance of managing the details of an entire growing system over the full life of the enterprise. Based on advances in scientific research in ecological food production, farmers, homesteaders, permaculturists, and gardeners alike will learn methods to: • design a farm system that maintains a growing root in the soil year-round to feed the microbial community instead of just crops • strengthen the “immune system” of a farm or garden • supply crop needs using only on-farm inputs such as cover crops and living mulch • maximize the presence of beneficial insects and microbes that support healthy crop development • minimize ecological impact in dealing with insect pest and disease problems This book also features a crop-by-crop guide to growing more than 25 of the most popular and profitable vegetables and fruits, including specific management advice for dealing with pests and diseases. The Ecological Farm makes complex, sometimes messy, ecological concepts and practices understandable to all growers, and makes healthy farming—in which nature is invited to participate—possible.
Download or read book Encyclopedia of Cancer written by Manfred Schwab and published by Springer Science & Business Media. This book was released on 2008-09-23 with total page 3307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.
Download or read book Defying Aging written by Conrad Riker and published by Conrad Riker. This book was released on 101-01-01 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: Are you tired of feeling like aging is an inevitable decline? Do you wish there was more you could do to maintain your youth and vitality? "Defying Aging: Science-Based Strategies for a Longer, Healthier Life" offers practical, evidence-based approaches to understanding and combating the aging process. In this book, we explore the complex mechanisms behind aging and how they can be manipulated or reversed. We delve into genetic factors, cellular processes, and the role of diet, exercise, and hormonal therapy in promoting longevity. As an added bonus, we also examine the potential of stem cell therapy and the importance of telomeres and telomerase in the aging process. In "Defying Aging", you will learn: - The role of inflammation and oxidative stress in aging and how to control them - How caloric restriction and lifestyle factors can influence the aging process - The truth behind anti-aging treatments, both proven and unproven - The potential future of anti-aging research and treatments If you want to take control of your health, optimize your life, and defy aging, then "Defying Aging: Science-Based Strategies for a Longer, Healthier Life" is the book for you. Start your journey towards a healthier, longer life today!
Download or read book Marginalized in the Middle written by Alan Wolfe and published by University of Chicago Press. This book was released on 1996 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Wolfe examines the ills of American society in the 1990s ... [and illustrates] the paradoxes of social criticism."--Jacket.
Download or read book Aging by the Book written by Kay Heath and published by State University of New York Press. This book was released on 2009-02-19 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uncovers the origins of midlife anxiety in Victorian print culture.
Download or read book Senescence written by Dennis Sidney Martin and published by Lulu.com. This book was released on 2019-12-20 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of poems about growing older with elegance and grace.
Download or read book Handbook of Sociology of Aging written by Richard A. Settersten, Jr. and published by Springer Science & Business Media. This book was released on 2011-05-11 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Sociology of Aging is the most comprehensive, engaging, and up-to-date treatment of developments within the field over the past 30 years. The volume represents an indispensable source of the freshest and highest standard scholarship for scholars, policy makers, and aging professionals alike. The Handbook of Sociology of Aging contains 45 far-reaching chapters, authored by nearly 80 of the most renowned experts, on the most pressing topics related to aging today. With its recurring attention to the social forces that shape human aging, and the social consequences and policy implications of it, the contents will be of interest to everyone who cares about what aging means for individuals, families, and societies. The chapters of the Handbook of Sociology of Aging illustrate the field’s extraordinary breadth and depth, which has never before been represented in a single volume. Its contributions address topics that range from foundational matters, such as classic and contemporary theories and methods, to topics of longstanding and emergent interest, such as social diversity and inequalities, social relationships, social institutions, economies and governments, social vulnerabilities, public health, and care arrangements. The volume closes with a set of personal essays by senior scholars who share their experiences and hopes for the field, and an essay by the editors that provides a roadmap for the decade ahead. The Handbook of Sociology of Aging showcases the very best that sociology has to offer the study of human aging.
Download or read book Interdisciplinary Perspectives on Aging in Nineteenth Century Culture written by Anne-Julia Zwierlein and published by Routledge. This book was released on 2013-08-15 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This essay collection develops new perspectives on constructions of old age in literary, legal, scientific and periodical cultures of the nineteenth century. Rigorously interdisciplinary, the book places leading researchers of old age in nineteenth-century literature in dialogue with experts from the fields of cultural, legal and social history. It revisits the origins of many modern debates about aging in the nineteenth century – a period that saw the emergence of cultural and scientific frameworks for the understanding of old age that continue to be influential today. The contributors provide fresh readings of canonical texts by Charles Dickens, Elizabeth Gaskell, Anthony Trollope, Thomas Hardy, Henry James and others. The volume builds momentum in the burgeoning field of aging studies. It argues that the study of old age in the nineteenth century has entered a new and distinctly interdisciplinary phase that is characterized by a set of research interests that are currently shared across a range of disciplines and that explore conceptions of old age in the nineteenth century by privileging, respectively, questions of agency, of place, of gender and sexuality, and of narrative and aesthetic form.
