Download or read book Mesenchymal Stem Cell Senescence and Rejuvenation written by Yuelin Zhang and published by Frontiers Media SA. This book was released on 2022-01-18 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Senescence and Rejuvenation written by Charles Sedgwick Minot and published by . This book was released on 1891 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ending Aging written by Aubrey de Grey and published by Macmillan + ORM. This book was released on 2007-09-04 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: MUST WE AGE? A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging. Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach. In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.
Download or read book Stem Cell Aging Mechanisms Consequences Rejuvenation written by Hartmut Geiger and published by Springer. This book was released on 2015-07-06 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging of somatic stem cells reduces cell function and results in dysfunctional organs and tissues, making it an underlying cause of diseases associated with aging. It might even be the primary cause for age-associated attrition of tissue function in organs that heavily rely on stem cells for maintaining homeostasis, like the skin, blood and intestines. Understanding the molecular and cellular mechanisms involved is critical for developing approaches to attenuate stem cell aging and could pave the way for improved quality of life among the elderly. Written by highly prominent experts in the field, this book presents the current state of knowledge on these mechanisms. It offers insights into stem cell function, explains in detail the mechanisms of stem cell aging in model organisms as well as mammalian systems and describes related diseases and approaches to attenuating stem cell aging or achieving rejuvenation. The book is intended for all scientists and clinicians working with stem cells, aging mechanisms or age-related diseases.
Download or read book Handbook Of Software Aging And Rejuvenation Fundamentals Methods Applications And Future Directions written by Tadashi Dohi and published by World Scientific. This book was released on 2020-04-22 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Software Aging and Rejuvenation provides a comprehensive overview of the subject, making it indispensable to graduate students as well as professionals in the field. It begins by introducing fundamental concepts, definitions, and the history of software aging and rejuvenation research, followed by methods, tools, and strategies that can be used to detect, analyze, and overcome software aging.
Download or read book Understanding the Molecular Interplay Between Senescence Rejuvenation and Healthy Ageing written by Eleanor Tyler and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Rejuvenation and Longevity written by Khachik K. Muradian and published by Springer Nature. This book was released on with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Mechanisms of the Aging Process and Rejuvenation written by Naofumi Shiomi and published by BoD – Books on Demand. This book was released on 2016-08-31 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerous studies had been performed to elucidate the mechanisms of aging and to achieve rejuvenation, with some success reported in recent years. However, at present, the findings from those studies are not sufficient to resolve the issue of aging. This book presents an overview of recent topics on cellular aging and rejuvenation. In the early chapters, the molecular mechanisms of aging via the activities of clock and ion channel proteins, in addition to overall aspects, are discussed. In the latter part, the aging of the skin, immune system, and brain is discussed. This book will prove useful for those studying or developing new drugs to counter the aging process and will encourage the development of novel ideas for rejuvenation.
Download or read book Sunlight Vitamin D and Skin Cancer written by Jörg Reichrath and published by Springer Nature. This book was released on 2020-09-11 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition is a comprehensive and updated overview of positive and negative effects of UV-exposure, with a focus on Vitamin D and skin cancer. Researchers, oncologists,and students will be provided with the most significant and timely information related to topics such as the epidemiology of skin cancer, the immune system and skin cancer, ultraviolet damage, DNA repair and Vitamin D in Nonmelanoma skin cancer and malignant melanoma. There have been a number of new, scientific findings in this fast moving field that necessitated a thoroughly updated and revised edition including new Vitamin D metabolites and skin cancer, new findings on the beneficial effects of UV and solar UV and skin cancer, adverse effects of sun protection and sunscreens, sun exposure and mortality, and more. The book will summarize essential, up-to-date information for every clinician or scientist interested in how to balance the positive and negative effects of UV‐exposure to minimize the risks of developing vitamin D deficiency and skin cancer.
Download or read book The Age of Obsolescence written by Erin Gentry Lamb and published by . This book was released on 2009 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book SUMMARY Ending Aging The Rejuvenation Breakthroughs That Could Reverse Human Aging In Our Lifetime By Aubrey De Grey And Michael Rae written by Shortcut Edition and published by Shortcut Edition. This book was released on 2021-06-05 with total page 19 pages. Available in PDF, EPUB and Kindle. Book excerpt: * Our summary is short, simple and pragmatic. It allows you to have the essential ideas of a big book in less than 30 minutes. As you read this summary, you will learn that an anthropological revolution such as the world has never known is at hand: not only slowing down and stopping the aging process, but even reversing it. You will also learn that : we have been conditioned since the dawn of time by the inevitability of aging and death; of the 150,000 people who die every day in the world, 100,000 die of old age; our reactions to revolutionary progress are sometimes irrational; the acceptance of the aging process must become increasingly politically incorrect; certain cellular and molecular changes must take place if we are to fight effectively against the aging process; a militant spirit is indispensable for the diffusion of the author's theses. All scientists who study the biology of aging agree on one point: one day, relatively soon, we will be able to reverse the aging process using techniques still under study today. Among these scientists, Dr. de Grey stands out for his constancy and combativeness. His fight against aging has become his raison d'être, and this book is a kind of manifesto. In this book, the author demystifies anti-aging techniques, making them easily accessible to all. A salutary work, which has already been praised by newspapers as serious as the "Wall Street Journal" or the "New York Times". *Buy now the summary of this book for the modest price of a cup of coffee!
Download or read book Stem Cells and Aging written by Surajit Pathak and published by Academic Press. This book was released on 2021-03-17 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cells and Aging covers what is known about the effect of time and age on the basic units of life, which are the corresponding tissue-specific or adult stem cells. Even though the concept of stem cells was introduced nearly a century ago by Alexander Maximow, modern stem-cell research began in 1963 when James Till, Ernest McCullough and Lou Siminovitch established assays to detect hematopoietic stem cells. In fact, given the importance of the aging-associated diseases, scientists have developed a keen interest in understanding the aging process as they attempt to define the role of dysfunctional stem cells in the aging process. With an aging population worldwide, understanding these age-related stem cell changes at a basic biology level and at the level of their influences for regenerative medicine is of interest and importance. There is increasing evidence that the aging process can have much adverse effects on stem cells. In the modern era, one of the emerging fields in treating human diseases is stem cell research, as stem cells have the remarkable potential to treat a wide range of diseases. Nevertheless, understanding the molecular mechanism involved in aging and deterioration of stem cell function is crucial in developing effective new therapies for aging. - Serves as an ideal reference to guide investigators toward valuable answers to the problems of our aging population - Addresses the effect of time and age on human stem cells - Includes chapters from contributors exploring the biology of stem cell aging around the globe
Download or read book Regenerative Nephrology written by Michael S. Goligorsky and published by Academic Press. This book was released on 2010-11-26 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progression of chronic diseases in general and chronic kidney disease in particular has been traditionally viewed in the light of various contributors to development of glomerulosclerosis and tubulointerstitial scarring culminating in renal fibrosis. Indeed, this dogma prevailed for decades underscoring experimental attempts to halt fibrotic processes. Breakthrough investigations of the past few years on stem/progenitor cell involvement in organ regeneration caused a conceptual shift in tackling the mechanisms of nephrosclerosis. It has become clear that the rate of progression of chronic kidney disease is the net sum of the opposing trends: degenerative fibrotic processes and regenerative repair mechanisms. The latter part of this equation has been by and large ignored for years and only recently attracted investigative attention. This book revisits the problem of kidney disease by focusing on regenerative mechanisms in renal repair and on the ways these regenerative processes can become subverted by an intrinsic disease process eventuating in its progression. Cutting-edge investigations are summarized by the most experienced international team of experts. - Presents a comprehensive, translational source for all aspects of renal stem cells, tissue regeneration, and stem cell therapies for renal diseases in one reference work. This will ultimately result in time savings for academic, medical and pharma researchers - Experts in the renal stem cell system in kidney repair and regeneration take readers from the bench research to new therapeutic approaches, providing a common language for nephrology researchers, fellows and other stem cell researchers. This enables the discussion of development of stem cells and their use in the repair and regeneration of the kidney
Download or read book Senescence and Rejuvenescence written by Charles Manning Child and published by Ayer Publishing. This book was released on 1979-01-01 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Rejuvenation written by Robert Buckingham MD FACP and published by True Directions. This book was released on 2017-07-18 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: If you're like most people, there's a gun pointed to your head and you don't even know it. Poor lifestyle choices can induce chronic inflammation that could result in serious or life-threatening illnesses and even death from heart attacks, strokes, debilitating arthritis, heart failure, dementia, cancers, and autoimmune disease. But no alarms go off when we smoke a cigarette, eat a large bag of fries, or inhale a donut--so most of us don't see the gun barrel. It keeps taking aim until one day it goes off. Robert Buckingham, MD, FACP, exposes the truth about the gun and what you must do to push it away, which begins by understanding how the body works. It turns out that whoever or whatever controls capillary cell outer membranes, controls mitochondrial combustion, which determines Rejuvenation. The battle is between inflammatory forces that work against end organs and those that support them. Find out the steps to take to reduce chronic inflammation so you can enjoy a longer and healthier life with the insights and action steps in this book.
Download or read book Stem Cell Epigenetics written by and published by Academic Press. This book was released on 2020-08-07 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Growing evidence suggests that epigenetic mechanisms play a central role in stem cell biology and are vital for determining gene expression during cellular differentiation and governing mammalian development. In Stem Cell Epigenetics, leading international researchers examine how chromatin regulation and bona fide epigenetic mechanisms underlie stem cell renewal and differentiation. Authors also explore how the diversity of cell types, including the extent revealed by single cell omic approaches, is achieved, and how such processes may be reversed or managed via epigenetic reprogramming. Topics discussed include chromatin in pluripotency, stem cells and DNA methylation, histone modifications in stem cells and differentiation, higher-order chromatin conformation in pluripotent cells, stem cells and cancer, epigenetics and disease modeling, brain organoids from pluripotent cells, transcriptional regulation in stem cells and differentiation, non-coding RNAs in pluripotency and early differentiation, and diseases caused by epigenetic alterations in stem cells. Additionally, the book discusses the potential implementation of stem cell epigenetics in drug discovery, regenerative medicine, and disease treatment. Stem Cell Epigenetics will provide researchers and physicians with a state-of-the-art map to orient across the frontiers of this fast-evolving field. Analyzes the role of epigenetics in embryonic stem cell regulation Indicates the epigenetic mechanisms involved in stem cell differentiation and highlights modifications and misregulations that may result in disease pathogenesis Examines the potential applications of stem cell epigenetics in therapeutic disease interventions and regenerative medicine, providing a foundation for researchers and physicians to bring this exciting and fast-evolving field into a clinical setting Features chapter contributions by leading international experts
Download or read book Translation of The Theory of Cyclic Senescence and Rejuvenation in Plants and Its Practical Application written by and published by . This book was released on 1940 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
