Download or read book Selected Papers of Charles H Best written by Charles Herbert Best and published by University of Toronto Press. This book was released on 1963-12-15 with total page 1187 pages. Available in PDF, EPUB and Kindle. Book excerpt: The name of Charles H. Best, co-discoverer of insulin, Head of the Department of Physiology and Director of the Banting and Best Department of Medical Research in the University of Toronto, is familiar to medical and lay readers all over the world. The story of his early insulin research with Dr. Frederick Banting, as a result of which men and women and children who forty years ago would have had only months or days to live are now spared, has been one of the most dramatic in the annals of medicine. This volume records the achievements of forty years of medical research, giving direct and easy access to over sixty of Dr. Best’s original important research papers in the fields particularly of insulin, heparin, and choline. It opens with the early papers describing the discovery of insulin, and continues with those dealing with its preparation, extraction, physiologic effects and first clinical applications. Dr. Best has also looked back over the record as given in these papers and provided informative and informal bridges between them which place them in historical perspective. Among medical scientists Dr. Best is equally well known for initiating and developing modern knowledge of heparin and its use in controlling unwanted clotting of the blood (thrombosis). The discovery of the nutritional importance of choline as a dietary factor that protects the liver was made by Dr. Best and his colleagues in 1932 and this subject has received continued study in Toronto. A number of papers dealing with choline and its dietary precursors (the so-called lipotropic agents) are reproduced in these pages. Other papers discuss the action of histamine, the pioneer Canadian work on collection and storage of blood serum and early experiences with the preparation of dried serum. A brief account of the contribution of Dr. Best and his colleagues to the Naval Medicine is included. Medical readers will find here a valuable condensation of all the enormous body of information on these subjects. All the references in the original papers have been re-assembled in a master bibliography which is a new and full storehouse of references. Most of the papers collected in this volume have been produced in collaboration with medical colleagues to whom Dr. Best at all times gives full and enthusiastic recognition. Indeed readers will receive a strong impression that while co-operation and collaboration in medicine are nothing new, the various teams assembled by Dr. Best at the University of Toronto have had an especially remarkable dedication and sense of excitement in the adventure of medical research.
Download or read book Selected Papers written by Charles Herbert Best and published by . This book was released on 1963 with total page 723 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Margaret and Charley written by Henry B.M. Best and published by Dundurn. This book was released on 2003-06-01 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although Charles Best is known for discovering insulin, the story of his life neither begins nor ends with that one moment. Not only did he make many other discoveries, he was also one half of an extraordinary couple who, during their almost sixty years together, were involved in many of the significant events of the twentieth century. Margaret & Charley is the story of these two people from their beginnings on the east coast at the turn of the century through the years that followed. Through diaries, scrapbooks, photograph albums, and other documentation, the details of their lives are shared with the reader.
Download or read book Doing Good written by J.T.H. Connor and published by University of Toronto Press. This book was released on 2000-12-15 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: A history of Toronto’s general hospital offers a window on a broader history of Upper Canada and Ontario over the last two centuries. In this lively and authoritative account, J.T.H. Connor traces the hospital’s two-hundred-year evolution, as its mandate to ‘do good’ forced constant adjustment to changing social, medical, and government attitudes. Doing Good presents the hospital’s history in three phases – roughly speaking, the first and second halves of the nineteenth century, and the twentieth century. From its conception in 1797 to the mid-1850s – it did not actually acquire a home until 1819 nor occupy it until 1829 – it functioned as a charitable institution, catering to the sick poor. It acted initially as a clearing station for sick immigrants; it later was deeply affected by political events and became embroiled in the medical turmoil of Toronto in the 1840s and early 1850s. In the second era, from the mid-1850s, it was a public charity, receiving stable government funding and constructing a new home in eastern Toronto. By the 1870s, it was winning praise as a model hospital. In the twentieth century, it early on established close links with the University of Toronto, building a vast and up-to-date new facility adjacent to the university, which opened in 1913. Its international reputation as an academic hospital grew over the decades to include a high profile in research, most notably in cancer and medical technology. By the 1960s the institution was being run as a public hospital, and the late 1990s saw its absorption into a hospital mega-corporation – the University Health Network – along with three other nearby hospitals. This work is the most comprehensive analysis of any Canadian hospital or health care institution yet to appear. Using trustees’ minutes, medical journals, newspapers, and government reports, along with correspondence, photographs, and reminiscences of trustees, nurses, doctors, and patients, Connor offers acute observation and detailed analysis, as well as compelling character studies and revealing anecdotes. Broad in scope and meticulously executed, Doing Good brings vividly to life the day-to-day routines, the behind-the-scenes intrigue, and the people and politics of a great urban hospital.
Download or read book Functional Perspectives on Grammar and Discourse written by Christopher S. Butler and published by John Benjamins Publishing. This book was released on 2007-07-13 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, a tribute to Angela Downing, consists of twenty papers taking a broadly functional perspective on language, with topics ranging from the general (grammar as an evolutionary product, text comprehension, integrative linguistics) to particular aspects of the grammars of languages (Bulgarian, English, Icelandic, Spanish, Swedish). The more specific papers are sequenced according to Halliday’s division into ideational, textual and interpersonal aspects of the grammar, and cover a wide range of areas, including aspect, argument structure, noun phrase/nominal group structure and nominalisations, pronominal clitics, theme in relation to writing skills, discourse structures and markers, the role of attention in conversation, the functions of topic, phatic communion, subjectification, formulaic language and modality. A recurrent theme in the volume is the use of corpus materials in order to base functional descriptions on authentic productions. Overall, the volume constitutes a panoramic but nevertheless detailed view of some important current trends in functional linguistics.
Download or read book The Discovery of Insulin written by Michael Bliss and published by University of Toronto Press. This book was released on 2017-06-22 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of insulin at the University of Toronto in 1921-22 was one of the most dramatic events in the history of the treatment of disease. Insulin was a wonder-drug with ability to bring patients back from the very brink of death, and it was no surprise that in 1923 the Nobel Prize for Medicine was awarded to its discoverers, the Canadian research team of Banting, Best, Collip, and Macleod. In this engaging and award-winning account, historian Michael Bliss recounts the fascinating story behind the discovery of insulin – a story as much filled with fiery confrontation and intense competition as medical dedication and scientific genius. Originally published in 1982 and updated in 1996, The Discovery of Insulin has won the City of Toronto Book Award, the Jason Hannah Medal of the Royal Society of Canada, and the William H. Welch Medal of the American Association for the History of Medicine.
Download or read book Secondary Sources in the History of Canadian Medicine written by Charles G. Roland and published by Wilfrid Laurier Univ. Press. This book was released on 2006-01-01 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work is a bibliography of secondary sources in Canadian medical history.
Download or read book Insulin written by Pedro Cuatrecasas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is fourteen years since insulin was last reviewed in The Handbook of Ex perimental Pharmacology, in volume 32. The present endeavor is more modest in scope. Volume 32 appeared in two separate parts, each having its own subeditors, and together the two parts covered nearly all areas of insulin pharmacology. Such comprehensiveness seemed impractical in a new volume. The amount of in formation related to insulin that is now available simply would not fit in a reasonable amount of space. Furthermore, for better or worse, scientists have be come so specialized that a volume providing such broad coverage seemed likely in its totality to be of interest or value to very few individuals. We therefore decided to limit the present volume to the following areas: insulin chemistry and structure, insulin biosynthesis and secretion, insulin receptor, and insulin action at the cellular level. We felt these areas formed a coherent unit. We also felt, perhaps as much because of our own interests and perspectives as any objective reality, that these were the areas in which recent progress has been most dramatic, and yet, paradoxically and tantalizingly, these were the areas in which most has yet to be learned. Even with this limited scope, there are some major gaps in coverage. Regrettably, two important areas, the beta cell ATP-sensitive potassium channel and the glucose transporter, were among these. Nevertheless, the authors who con tributed have done an excellent job, and we would like to thank them for their diligence.
Download or read book Advances in Enzymology and Related Areas of Molecular Biology written by Alton Meister and published by John Wiley & Sons. This book was released on 2009-09-15 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Enzymology and Related Areas of Molecular Biology is a seminal series in the field of biochemistry, offering researchers access to authoritative reviews of the latest discoveries in all areas of enzymology and molecular biology. These landmark volumes date back to 1941, providing an unrivaled view of the historical development of enzymology. The series offers researchers the latest understanding of enzymes, their mechanisms, reactions and evolution, roles in complex biological process, and their application in both the laboratory and industry. Each volume in the series features contributions by leading pioneers and investigators in the field from around the world. All articles are carefully edited to ensure thoroughness, quality, and readability. With its wide range of topics and long historical pedigree, Advances in Enzymology and Related Areas of Molecular Biology can be used not only by students and researchers in molecular biology, biochemistry, and enzymology, but also by any scientist interested in the discovery of an enzyme, its properties, and its applications.
Download or read book The Discovery of Insulin at the University of Toronto written by Thomas Fisher Rare Book Library and published by . This book was released on 1996 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1998. Gift from the publisher.
Download or read book The Publishers Trade List Annual written by and published by . This book was released on 1986 with total page 1138 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bulletin of the Menninger Clinic written by Menninger Clinic and published by . This book was released on 1964 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bulletin of the History of Medicine written by and published by . This book was released on 1965 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1939- include the Transactions of the 15th- annual meetings of the American Association of the History of Medicine, 1939-
Download or read book The Roll of the Royal College of Physicians of London Continued to 1983 written by Royal College of Physicians of London and published by . This book was released on 1984 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Connecting Cultures written by Hans Bak and published by Vu University Press. This book was released on 1994 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Zeven essays over migratie, overtocht en vestiging in de Verenigde Staten met aandacht voor de assimilatie van Nederlandse vrouwen, gevolgd door zeven essays over intellectuele en culturele uitwisseling tussen beide landen
Download or read book Great Events from History written by Robert F. Gorman and published by . This book was released on 2007 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contains essays that examine significant events in the history of the early twentieth century from 1901 to 1940, covering world politics, society and culture, literary movements, art and music, immigration, and legislation; arranged chronologically with maps, illustrations, and quotations for primary souce documents.
Download or read book The Two Thousand Men of Achievement written by and published by . This book was released on 1969 with total page 1040 pages. Available in PDF, EPUB and Kindle. Book excerpt:
