Download or read book Scientific American Molecular Cardiovascular Medicine written by Edgar Haber and published by . This book was released on 1995 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Scientific American Molecular Cardiovascular Medicine written by Edgar Haber and published by Mosby. This book was released on 1995 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Scientific American Introduction to Molecular Medicine written by Scientific American, inc and published by Scientific American Medicine. This book was released on 1994 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cardiovascular Physiology in the Genetically Engineered Mouse written by Brian D. Hoit and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enormous advances in molecular biology and genetics coupled with the progress in instrumentation and surgical techniques have produced a voluminous and often bewildering quantity of data. The need for a second edition of Cardiovascular Physiology in the Genetically Engineered Mouse is underscored not only by these rapid advances, but by the increasing numbers of scientists who have focussed their research on genetically engineered mice. It is the primary objective of this second edition to interpret critically the literature and to provide a framework for the enormous amount of information in this burgeoning field. As in the first edition, the monograph serves as a practical guide for the investigator interested in the functional methods used to characterize the murine cardiovascular phenotype. However, this guidebook is a more comprehensive text than its predecessor; although the major objectives enumerated in the first edition have not substantially changed, they have been refined in keeping with the increased sophistication of the molecular biologist, geneticist, and physiologist in each other's discipline. Each chapter has been expanded and updated, richly enhanced with original tables and figures, and in many cases, extensively rewritten. Eight chapters written by internationally recognized experts have been added; this represents a 43 % increase from the first edition.
Download or read book Molecular Diagnostics written by William B. Coleman and published by Springer Science & Business Media. This book was released on 2013-04-18 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Notable practitioners describe how laboratory medicine is practiced today and illuminate how it will function tomorrow as the revolutionary advances afforded by molecular diagnostics become increasingly central to effective analysis. Proceeding from a discussion of elementary nucleic acid technology to a review of the more advanced techniques, the distinguished contributors lay the groundwork for a comprehensive understanding of their applications throughout clinical medicine. The result is a detailed description of those molecular technologies currently used in diagnostic laboratories, as well as those that seem particularly promising. Detailed discussions of specific clinical applications include those for cancer, hematological malignancies, cardiovascular disease, and neuromuscular, endocrine, and infectious diseases.
Download or read book Principles of Molecular Regulation written by P. Michael Conn and published by Springer Science & Business Media. This book was released on 2000-07-28 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the dramatic growth in our knowledge of hormone action and the mechanisms of cell regulation, the need for an up-to-date broad-ranging survey of these processes has become pressing. In Principles of Molecular Regulation, P. Michael Conn and Anthony Means have successfully assembled a panel of leading investigators to provide an integrated review of the key areas-membrane receptor-initiated cell signaling and nuclear receptor-initiated gene regulation. Chosen for the excellence of their research as well as their demonstrated writing skills, these distinguished authors illuminate the molecular machinery underlying the regulatory processes of cells. In addition to their comprehensive review of the signaling mechanisms involving cell surface receptors, nuclear receptors, and ion channels, they detail the roles of calcium, lipids, cyclic AMP, protein kinases, and protein phosphatases. They also discuss the molecular regulation of cell proliferation and death, as well as the impact of new technologies on rational drug discovery. Capturing the excitement now present at this vibrant union of molecular biology, cell biology, and endocrinology, Principles of Molecular Regulation constitutes a major new resource for understanding the many and complex elements of biological regulation. Its up-to-date critical synthesis is certain to prove of high value to all basic and clinical investigators working with these processes today.
Download or read book Molecular Genetics of Cardiac Electrophysiology written by C. Berul and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: The molecular basis for atrial fibrillation continues to be largely unknown, and therapy remains unchanged, aimed at controlling the heart rate and preventing systemic emboli with anticoagulation. Familial atrial fibrillation is more common than previously suspected. While atrial fibrillation is commonly associated with acquired heart disease, a significant proportion of individuals have early onset without other forms of heart disease, referred to as "lone" atrial fibrillators. It is also well recognized that atrial fibrillation occurs on a reversible or functional basis, without associated structural heart disease, such as with hyperthyroidism or of atrial fibrillation following surgery. It remains to be determined what percentage in these individuals is familial or due to a genetic predisposition. Mapping the locus for familial atrial fibrillation is the first step towards the identification of the gene. Isolation of the gene and subsequent identification of the responsible molecular genetic defect should provide a point of entry into the mechanism responsible for the familial form and the common acquired forms of the disease and eventually provide more effective therapy. We know that the ionic currents responsible for the action potential of the atrium is due to multiple channel proteins as is electrical conduction throughout the atria. Analogous to the ongoing genetic studies in patients with familial long QT syndrome, it is highly likely that defects in each of these channel proteins will be manifested in familial atrial fibrillation.
Download or read book Diagnosis and Management of Hypertrophic Cardiomyopathy written by Barry J. Maron and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnosis and Management of Hypertrophic Cardiomyopathy is aunique, multi-authored compendium of information regarding thecomplexities of clinical and genetic diagnosis, natural history,and management of hypertrophic cardiomyopathy (HCM)—the mostcommon and important of the genetic cardiovasculardiseases—as well as related issues impacting the health oftrained athletes. Edited by Dr. Barry J. Maron, a world authority on HCM, and withmajor contributions from all of the international experts in thisfield, this book provides a single comprehensive source ofinformation concerning HCM. Recent advances in the field arediscussed, including the importance of left ventricular outflowtract obstruction, the use of implantable defibrillators for theprevention of sudden death in young people, definition of thegenetic basis for HCM and its role in clinical diagnosis and riskstratification, the development of more precise strategies forassessing the level of risk for sudden death among all patientswith HCM, and the evolution of invasive interventions for heartfailure symptoms, such as surgical management and its alternatives(alcohol septal ablation and dual-chamber pacing). Key Features: Contributions from all experts in the field,representing diverse viewpoints regarding this heterogeneousdisease and related issues in athletes Information to dispel misunderstandings regarding issuesassociated with HCM and cardiovascular disease in athletes The only comprehensive source of information available on thetopic
Download or read book Cardiovascular Disease written by Linda L. Gallo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fourteenth Washington International Spring Symposium, held in Washington, D.C., in June 1994, brought together over 400 leading scientists from 21 countries to review and update research on cardiovascular disease. This group satisfied the symposium goals of formulating a more comprehensive and integrated picture of the events contributing to atherosclerosis and of exploring modified gene expression as an to understanding the causes of atherosclerosis and providing clues to the approach prevention and treatment. This volume contains most of the papers presented at the eight plenary sessions together with selected contributions from the special sessions. The multidisciplinary nature of the chapters and their authors should stimulate the interests of biochemists, cell and molecular biologists, pathologists, pharmacologists, epidemiologists, nutritionists, and clinicians. The volume is divided into eight sections which reflect the focus of the plenary sessions. Part I focuses on the pathophysiology of atherosclerotic plaques and predicts that the nature of the fibrous cap of atheroma determines plaque disruption and clinical events. Papers in Part II deal with atherogenic lipoproteins. The introductory paper reviews the current view of the role of plasma lipoproteins in atherosclerosis. With respect to the newer members on the list,: [oxidized LDL, Lp(a)] evidence is provided that suggests the involvement of one major gene in the development of oxidized LDL lipids. the expression of inflammatory genes, and the development of aortic fatty streaks.
Download or read book Primary Care written by Robert V. DiGregorio, PharmD, BCACP and published by Springer Publishing Company. This book was released on 2014-11-12 with total page 1096 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete, state-of-the-art bible of interprofessional primary care in one easy-to-use resource for Interprofessional Primary Care A truly interprofessional primary care textbook, created by DNPs/APRNs, MDs, PharmDs, PAs, CNSs, and CNMs Evidence-based practice guidelines for Primary Care Includes community care, team work, and wellness coachings Strong guidance on differential diagnosis, disease prevention, risk reduction and lifestyle management Across the lifespan focus PLUS gender, occupational and palliative care considerations Case Studies in PPT format available to faculty adopting the text This second edition of Primary Care delivers succinct, current, and integrated information on the assessment, differential diagnosis, treatment, and management of individuals with commonly seen conditions in primary care settings. Written and edited by APNs, MDs, PAs, PharmDs and other health professionals, it emphasizes guidance on differential diagnosis, interprofessional primary care, lifestyle management, health promotion, risk reduction, and disease prevention. The text features ërelationship-centered care, extensive coverage of age, gender, and occupational considerations; complementary approaches; nutritional assessment; violence exposure and vulnerability assessment; family, community, and cultural assessment; palliative care; and evidence-based practice guidelines. This important text presents current diagnostic criteria for each condition and includes relevant anatomy, pathology, and physiology, epidemiology of the condition, including cultural and economic factors, risk identification, and disease prevention strategies. Also included are related laboratory studies, the focused physical exam, wellness coaching, treatment options, potential pitfalls, and much more. Additionally, the book includes clinical "pearls", clinical warnings, referrals and warning points, and references. The text is of value to all interprofessional primary care providers, with a special focus on the needs of advanced practice nurses and MSN/DNP students, and as a course textbook for teaching primary health care topics New to the Second Edition: Increased focus on interprofessional primary care, including community care, team work, and wellness coaching Strong guidance on differential diagnosis, disease prevention, risk reduction and lifestyle management Broad team of interprofessional authors and editors Special focus on elder/geriatric primary care and palliative care Evidence-based practice guidelines Stronger focus on age, gender, and occupational considerationsFocus on age, gender, and occupational considerations Case Studies in PPT format available to faculty adopting the text
Download or read book Endothelial Cells in Health and Disease written by William C. Aird and published by CRC Press. This book was released on 2005-02-28 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference serves as the first source to gather current data from endothelial cell biologists in various disciplines to summarize recent progress in the field-providing a complete understanding of the endothelium in health and disease and demonstrating its potential as a therapeutic target.
Download or read book Mechanical Forces and the Endothelium written by Michael A Gimbrone and published by CRC Press. This book was released on 1999-08-19 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Areas addressed in this excellent text include the overall response of the endothelium to hemodynamic forces, and molecular biology with gene regulation taking a central role.
Download or read book Primary Care Second Edition written by Joanne K. Singleton and published by Springer Publishing Company. This book was released on 2014-11-12 with total page 1096 pages. Available in PDF, EPUB and Kindle. Book excerpt: Print+CourseSmart
Download or read book Handbook of Clinical Nursing Research written by Ada Sue Hinshaw and published by SAGE Publications. This book was released on 1999-06-18 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: This ambitious and long-awaited volume brings together foremost nursing scholars, researchers, and educators to review and critique the state of research across areas most relevant to clinical practice. The contributorship appears as a veritable "who′s who" of nursing research and the contents comprise primary areas in the vanguard of nursing science. In the first section, the authors explore theoretical issues, the variety of philosophical approaches to scientific inquiry in nursing, factors shaping nursing research, and the relationship of the philosophical perspectives to research methodologies. In later sections, the scientists review and analyze the state of nursing science in relation to community health, practice strategies, family care, health promotion, biobehavioral investigations, women′s health, gerontologic nursing, and health system perspectives and outcomes. For physiological as well as psychological research, the most relevant theories driving the research are presented along with the review of multiple diverse instruments and measurement issues. Comprehensive in scope, cogent and truly thought provoking, a book such as the Handbook of Clinical Nursing Research arrives only once or twice in a career. It is a must-have shelf reference for every nurse and for those who would teach them.
Download or read book Comprehensive Toxicology written by and published by Elsevier. This book was released on 2010-06-01 with total page 6448 pages. Available in PDF, EPUB and Kindle. Book excerpt: An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version
Download or read book Endothelial Dysfunctions in Vascular Disease written by Raffaele De Caterina and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between the laboratory and the bedside, this timely volume illuminates the connection between endothelial dysfunction and vascular disease. This comprehensive survey of atherosclerotic disease begins with biology – incorporating the latest breakthroughs in the field – then elucidates risk factors and diagnostic tools and markers. A major section on endothelium-directed prevention and therapy shows you how to apply cutting-edge research to clinical care. Under the careful editorial guidance of Drs. De Caterina and Libby, the highly-regarded contributors address: endothelial activation and the initiation of atherosclerosis mechanisms of plaque progression and complications the role of LDL in the origin and progression of atherosclerosis advanced glycation endproducts and the accelerated atherosclerosis in diabetes oxidative stress and vascular disease soluble adhesion molecules as markers of vascular disease hormone-replacement therapy and cardiovascular risk anti-oxidants and endothelial protection and more. The first book dedicated to the central role of endothelial dysfunction in vascular disease, this concise volume gathers all the latest information on the subject into one convenient and cohesive text. Make sure your patients are benefiting from current knowledge by keeping a copy of Enothelial Dysfunctions in Vascular Disease close at hand for frequent consultation. Introduction Every book has a history, this one not excepted, having emerged from intersections in professional lives of the Editors. This book bears the fruits of a collaboration between the “pupil” (RDC) and the “mentor” (PL). During an extended sabbatical of the pupil in Boston in 1994, we probed together the concept that endothelial dysfunction served as a common denominator of vascular disease, with the balance between inflammation and its inhibition as a fulcrum of the regulation of the behavior of endothelial cells. As practicing cardiologists in our clinical lives, we sought to link to endothelial function the mechanisms of action of risk factors and of pharmacologic agents used to treat and prevent vascular disease. The pupil therefore authored a few reviews on the mechanism of action of risk factors and included them in a small book, published in Italian, for which the mentor wrote a preface. The book was greeted with favor from the Italian cardiological community, and provided the nidus for the present, more ambitious endeavor, which includes updated reviews on the pathogenesis of vascular disease and on the most novel aspects of vascular biology. This enterprise was enabled by the contributions of many of our former or present collaborators and colleagues, without whose enthusiasm and engagement this work could never have seen light. We largely underestimated the devotion necessary on our own side at the beginning, but it ultimately yielded a product that we feel achieves our original goals. We are aware that we confront a continuously evolving topic, where frequent updates would be desirable - if not necessary. Yet, we believe in the value of books - such as the current one - that attempt to organize in a snapshot of time, the vast amount of literature available in a coherent and comprehensive scheme. We are aware of existing gaps, of emerging material not paid its due, and of the rapid evolution of some of the concepts highlighted within. The links between the laboratory and the clinic have never afforded more opportunity for new understanding and advances in diagnosis and treatment than today We hope that our colleagues, vascular biologists cardiologists, internists, and other physicians alike will find this compendium a useful guide to this most exciting time in vascular biology and medicine —Raffaele De Caterina and Peter Libby
Download or read book Genomic and Molecular Cardiovascular Medicine written by Dhavendra Kumar and published by Elsevier. This book was released on 2024-06-24 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Genomic and Molecular Cardiovascular Medicine largely focuses on pertinent genomic and molecular aspects of cardiovascular medicine relevant to all levels of clinical practice, from primary care to preventive healthcare. The book also focuses on practice applications of translational genomic and molecular developments and advances that impact on cardiovascular system structure and function. Each chapter is evidence-based and comprehensive, with in-depth, cutting-edge knowledge relevant to the practice of clinical cardiology and cardiovascular surgery. The book aims to fill a major gap of knowledge resource focused on genomic and molecular aspects of contemporary cardiovascular medicine and surgery practice. In view of scientific and technical complexities of the field, the book is written by a team of globally acknowledged experts in respective clinical, investigative, therapeutic and preventive aspects. The current practices within cardiovascular medicine and surgery offer excellent opportunity for genomic and molecular applications to achieve the high order effectiveness with maximum efficiency. Includes clinical applications of genomic and molecular new knowledge, along with advances in the practice of cardiovascular medicine and surgery Provides wide coverage of all major clinical and preventive aspects of clinical cardiology, including multi-disciplinary team care Focuses on targeted gene and molecular therapy in clinical cardiovascular medicine and surgery
