Download or read book Medical Product Safety Evaluation written by Jie Chen and published by CRC Press. This book was released on 2018-09-03 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Product Safety Evaluation: Biological Models and Statistical Methods presents cutting-edge biological models and statistical methods that are tailored to specific objectives and data types for safety analysis and benefit-risk assessment. Some frequently encountered issues and challenges in the design and analysis of safety studies are discussed with illustrative applications and examples. Medical Product Safety Evaluation: Biological Models and Statistical Methods presents cutting-edge biological models and statistical methods that are tailored to specific objectives and data types for safety analysis and benefit-risk assessment. Some frequently encountered issues and challenges in the design and analysis of safety studies are discussed with illustrative applications and examples. The book is designed not only for biopharmaceutical professionals, such as statisticians, safety specialists, pharmacovigilance experts, and pharmacoepidemiologists, who can use the book as self-learning materials or in short courses or training programs, but also for graduate students in statistics and biomedical data science for a one-semester course. Each chapter provides supplements and problems as more readings and exercises.
Download or read book Departments of Transportation and Housing and Urban Development and Related Agencies Appropriations for 2017 written by United States. Congress. House. Committee on Appropriations. Subcommittee on Transportation, Housing and Urban Development, and Related Agencies and published by . This book was released on 2016 with total page 1564 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Highway Safety Analytics and Modeling written by Dominique Lord and published by Elsevier. This book was released on 2021-02-27 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highway Safety Analytics and Modeling comprehensively covers the key elements needed to make effective transportation engineering and policy decisions based on highway safety data analysis in a single. reference. The book includes all aspects of the decision-making process, from collecting and assembling data to developing models and evaluating analysis results. It discusses the challenges of working with crash and naturalistic data, identifies problems and proposes well-researched methods to solve them. Finally, the book examines the nuances associated with safety data analysis and shows how to best use the information to develop countermeasures, policies, and programs to reduce the frequency and severity of traffic crashes. - Complements the Highway Safety Manual by the American Association of State Highway and Transportation Officials - Provides examples and case studies for most models and methods - Includes learning aids such as online data, examples and solutions to problems
Download or read book Quantitative Drug Safety and Benefit Risk Evaluation written by William Wang and published by CRC Press. This book was released on 2021-12-30 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Methodologies and Process for Safety Monitoring and Ongoing Benefit Risk Evaluation provides a comprehensive coverage on safety monitoring methodologies, covering both global trends and regional initiatives. Pharmacovigilance has traditionally focused on the handling of individual adverse event reports however recently there had been a shift towards aggregate analysis to better understand the scope of product risks. Written to be accessible not only to statisticians but also to safety scientists with a quantitative interest, this book aims to bridge the gap in knowledge between medical and statistical fields creating a truly multi-disciplinary approach that is very much needed for 21st century safety evaluation.
Download or read book Proceedings of AICCE 19 written by Fadzli Mohamed Nazri and published by Springer Nature. This book was released on 2019-11-28 with total page 1635 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers the latest research, innovations, and applications in the field of civil engineering, as presented by leading national and international academics, researchers, engineers, and postgraduate students at the AWAM International Conference on Civil Engineering 2019 (AICCE’19), held in Penang, Malaysia on August 21-22, 2019. The book covers highly diverse topics in the main fields of civil engineering, including structural and earthquake engineering, environmental engineering, geotechnical engineering, highway and transportation engineering, water resources engineering, and geomatic and construction management. In line with the conference theme, “Transforming the Nation for a Sustainable Tomorrow”, which relates to the United Nations’ 17 Global Goals for Sustainable Development, it highlights important elements in the planning and development stages to establish design standards beneficial to the environment and its surroundings. The contributions introduce numerous exciting ideas that spur novel research directions and foster multidisciplinary collaborations between various specialists in the field of civil engineering.
Download or read book 14th WCEAM Proceedings written by Adolfo Crespo Márquez and published by Springer Nature. This book was released on 2020-12-02 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers selected peer-reviewed papers from the 14th World Congress on Engineering Asset Management (WCEAM), which was held in Singapore on 28–31 July 2019, as well as papers presented during the 1st WCEAMOnline event which focused on the ramifications of Covid-19 on infrastructure systems. This book covers a wide range of topics in engineering asset management, including: asset management services provisioning; servitization; decision-making; asset management systems; industrial Internet of things; and vulnerability and resilience of infrastructure systems. The breadth and depth of these state-of-the-art, comprehensive proceedings make them an excellent resource for asset management practitioners, researchers and academics, as well as undergraduate and postgraduate students.
Download or read book Environmental Risk Assessment written by Ted Simon and published by CRC Press. This book was released on 2019-12-06 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of risk assessment is to support science-based decisions about how to solve complex societal problems. Indeed, the problems humankind faces in the 21st century have many social, political, and technical complexities. Environmental risk assessment in particular is of increasing importance as health and safety regulations grow and become more complicated. Environmental Risk Assessment: A Toxicological Approach, 2nd Edition looks at various factors relating to exposure and toxicity, human health, and risk. In addition to the original chapters being updated and expanded upon, four new chapters discuss current software and platforms that have recently been developed and provide examples of risk characterizations and scenarios. Features: Introduces the science of risk assessment—past, present, and future Provides environmental sampling data for conducting practice risk assessments Considers how bias and conflict of interest affect science-based decisions in the 21st century Includes fully worked examples, case studies, discussion questions, and suggestions for additional reading Discusses new software and computational platforms that have developed since the first edition Aimed at the next generation of risk assessors and students who need to know more about developing, conducting, and interpreting risk assessments, the book delivers a comprehensive view of the field, complete with sufficient background to enable readers to probe for themselves the science underlying the key issues in environmental risk.
Download or read book Biocompatibility and Performance of Medical Devices written by Jean-Pierre Boutrand and published by Woodhead Publishing. This book was released on 2019-11-21 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biocompatibility and Performance of Medical Devices, Second Edition, provides an understanding of the biocompatibility and performance tests for ensuring that biomaterials and medical devices are safe and will perform as expected in the biological environment. Sections cover key concepts and challenges faced in relation to biocompatibility in medical devices, discuss the evaluation and characterization of biocompatibility in medical devices, describe preclinical performance studies for bone, dental and soft tissue implants, and provide information on the regulation of medical devices in the European Union, Japan and China. The book concludes with a review of histopathology principles for biocompatibility and performance studies. - Presents diverse insights from experts in government, industry and academia - Delivers a comprehensive overview of testing and interpreting medical device performance - Expanded to include new information, including sections on managing extractables, accelerating and simplifying medical device development through screening and alternative biocompatibility methods, and quality strategies which fasten device access to market
Download or read book Toxicological Risk Assessment and Multi System Health Impacts from Exposure written by Aristidis M. Tsatsakis and published by Elsevier. This book was released on 2021-08-01 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants. The book describes the cellular, biological, immunological, endocrinologic, genetic, and epigenetic effects of long-term exposure. It examines how the combined exposure to nanomaterials, metals, pharmaceuticals, multifrequency radiation, dietary mycotoxins, and pesticides accelerates ecotoxicity in humans, animals, plants, and the larger environment. The book goes on to also offer insights into mixture risk assessments, protocols for evaluating the risks, and how this information can serve the regulatory agencies in setting safer exposure limits. The book is a go-to resource for scientists and professionals in the field tackling the current and emerging trends in modern toxicology and risk assessment. - Bridges basic research with clinical, epidemiological, regulatory, and translational research, conveying both an introductory understanding and the latest developments in the field - Evaluates real-life human health risk assessment for long-term exposures to xenobiotic mixtures and the role they play in contributing to chronic disease - Discusses advances in predictive (in silico) toxicology tools and the benefits of using omics technologies in toxicology research
Download or read book Quantitative Methods in Pharmaceutical Research and Development written by Olga V. Marchenko and published by Springer Nature. This book was released on 2020-09-24 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contributed volume presents an overview of concepts, methods, and applications used in several quantitative areas of drug research, development, and marketing. Chapters bring together the theories and applications of various disciplines, allowing readers to learn more about quantitative fields, and to better recognize the differences between them. Because it provides a thorough overview, this will serve as a self-contained resource for readers interested in the pharmaceutical industry, and the quantitative methods that serve as its foundation. Specific disciplines covered include: Biostatistics Pharmacometrics Genomics Bioinformatics Pharmacoepidemiology Commercial analytics Operational analytics Quantitative Methods in Pharmaceutical Research and Development is ideal for undergraduate students interested in learning about real-world applications of quantitative methods, and the potential career options open to them. It will also be of interest to experts working in these areas.
Download or read book Power Systems Control and Reliability written by Isa S. Qamber and published by CRC Press. This book was released on 2020-03-13 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on power systems reliability and generating unit commitments, which are essential in the design and evaluation of the electric power systems for planning, control, and operation, this informative volume covers the concepts of basic reliability engineering, such as power system spinning reserve, types of load curves and their objectives and benefits, the electric power exchange, and the system operation constraints. The author explains how the probability theory plays an important role in reliability applications and discusses the probability applications in electric power systems that led to the development of the mathematical models that are illustrated in the book. The algorithms that are presented throughout the chapters will help researchers and engineers to implement their own suitable programs where needed and will also be valuable for students. The Artificial Neural Networks (ANN) and Fuzzy Logic (FL) systems are discussed and a number of load estimation models are built for some cases, where their formulas are developed. A number of developed models are presented, including the Kronecker techniques, Fourth-Order Runge-Kutta, System Multiplication Method, or Adams Method; and components with different connections and different distributions are presented. A number of examples are explained showing how to build and evaluate power plants.
Download or read book Systems Medicine written by and published by Academic Press. This book was released on 2020-08-24 with total page 1571 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technological advances in generated molecular and cell biological data are transforming biomedical research. Sequencing, multi-omics and imaging technologies are likely to have deep impact on the future of medical practice. In parallel to technological developments, methodologies to gather, integrate, visualize and analyze heterogeneous and large-scale data sets are needed to develop new approaches for diagnosis, prognosis and therapy. Systems Medicine: Integrative, Qualitative and Computational Approaches is an innovative, interdisciplinary and integrative approach that extends the concept of systems biology and the unprecedented insights that computational methods and mathematical modeling offer of the interactions and network behavior of complex biological systems, to novel clinically relevant applications for the design of more successful prognostic, diagnostic and therapeutic approaches. This 3 volume work features 132 entries from renowned experts in the fields and covers the tools, methods, algorithms and data analysis workflows used for integrating and analyzing multi-dimensional data routinely generated in clinical settings with the aim of providing medical practitioners with robust clinical decision support systems. Importantly the work delves into the applications of systems medicine in areas such as tumor systems biology, metabolic and cardiovascular diseases as well as immunology and infectious diseases amongst others. This is a fundamental resource for biomedical students and researchers as well as medical practitioners who need to need to adopt advances in computational tools and methods into the clinical practice. Encyclopedic coverage: ‘one-stop’ resource for access to information written by world-leading scholars in the field of Systems Biology and Systems Medicine, with easy cross-referencing of related articles to promote understanding and further research Authoritative: the whole work is authored and edited by recognized experts in the field, with a range of different expertise, ensuring a high quality standard Digitally innovative: Hyperlinked references and further readings, cross-references and diagrams/images will allow readers to easily navigate a wealth of information
Download or read book Public Community Health and Nursing Practice written by Christine L Savage and published by F.A. Davis. This book was released on 2019-09-20 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique, problem-solving, case-based approach shows you how. You’ll encounter different case studies in every chapter—that explore concepts such as community assessments, public health policy, and surveillance. Step by step, you’ll develop the knowledge and skills you need to apply public health principles across a variety of health care settings, special populations, and scenarios.
Download or read book Principles of Occupational Health and Hygiene written by Sue Reed and published by Routledge. This book was released on 2020-07-27 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Occupational Health and Hygiene offers a comprehensive overview of occupational health risks and hazardous environments encountered in a range of industries and organisational settings. Leading industry professionals and educators explain how to identify key workplace hazards including chemical agents such as dusts, metals and gases; physical agents such as noise, radiation and extremes of heat and cold; and microbiological agents. They outline assessment procedures and processes for identifying exposure levels. They also explain how to evaluate risk and follow safety guidelines to control and manage these hazards effectively. Chapters are heavily illustrated with detailed case studies, diagrams, flowcharts and photos. Practical guidelines are provided for managing each hazard type. This third edition has been extensively revised and updated and reflects current research evidence and the Workplace Health and Safety legislation on workplace hazards. Principles of Occupational Health and Hygiene is an essential reference for Occupational Hygienists and anyone in an Occupational Health and Safety role.
Download or read book Moving Towards Everlasting Artificial Intelligent Battery Powered Implants written by Marvellous Moyo and published by Elsevier. This book was released on 2024-10-15 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Moving Towards Everlasting Artificial Intelligent Battery-Powered Implants presents the development process of new artificial intelligent (AI) charging systems for battery-powered implants that can last for a lifetime after implantation. This book introduces new strategies to address the limitations of technologies that have been employed to improve the lifespan of medical implants. This book also provides guidelines that medical implant manufacturers can adopt during their product development stages—this adds a new dimension of research on medical device implants that can be a game changer for the AI medical implants industry. Researchers, engineers, and graduate students in the elds of biomedical engineering, electrical engineering, and computer science will find this text helpful as they seek to understand the potential of AI systems to help achieve sustainability in healthcare and make current medical implants relevant in the future. - Presents basic and advanced concepts in medical implants design - Explores various uses of AI and engineering concepts in optimization and enhancement of medical devices - Facilitates new approaches in improving patient safety and reliability of medical devices
Download or read book Green Chemistry in Government and Industry written by Mark Anthony Benvenuto and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-09-21 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 5th volume of Green Chemical Processing considers sustainable chemistry in the context of governmental and corporate interests, explaining how “red tape” can help or hinder the “greening” of industry processes. The American Chemical Society’s 12 Principles of Green Chemistry are woven throughout this text as well as the series to which this book belongs.
Download or read book Ubiquitous Computing and the Internet of Things Prerequisites for the Development of ICT written by Elena G. Popkova and published by Springer. This book was released on 2019-05-15 with total page 1175 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers the outcomes of several scientific events that were organized and conducted by the Institute of Scientific Communications (Volgograd, Russia) and the leading universities of the Volgograd region. The contributing authors include more than 700 scholars from various cities and regions of Russia. 124 works were selected out of 3,000 papers on the preconditions of formation, transformation, and legal provision of social institutes, topics that are in high demand in connection with a core aspect of digital modernization – the Internet of Things. The book is intended for a broad target audience, including scholars of various generations and various disciplines. These include young researchers (undergraduates and postgraduates) and recognized scholars (professors and lecturers) who study the socio-economic and legal consequences of the emergence and dissemination of digital technologies, including the Internet of Things. In addition, the book will benefit all those who are interested in the development of the information society, information and telecommunication, and digital technologies. The content is divided into three logical parts, the first of which is devoted to the essence of the process of institutionalization and legal regulation of the information society. In the second part, the digital economy is analyzed in view of the spheres of the national economy. In the third, the authors study the peculiarities of state and corporate regulation, infrastructural provision and support for the security of entrepreneurship, which are currently developing on the basis of the Internet of Things.
