Download or read book Role of Trans 10 Cis 12 Conjugated Linoleic Acid CLA and Other CLA Isomers in the Regulation of Milk Fat Synthesis and Lipid Metabolism written by James W. Perfield and published by . This book was released on 2006 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Role of Trans 10 Cis 12 Conjugated Linoleic Acid CLA and Other CLA Isomers in the Regulation of Milk Fat Synthesis and Lipid Metabolism written by James W. Perfield (II.) and published by . This book was released on 2006 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Milk fat depression (MFD) is a challenging problem that involves the interrelationship between digestive processes in the rumen and the synthesis of milk fat by the mammary gland. Recent investigations have resulted in the biohydrogenation theory to explain MFD, and the concept that under certain dietary conditions pathways of rumen biohydrogenation are altered to produce unique fatty acid intermediates, some of which are potent inhibitors of milk fat synthesis. Trans-10, cis-12 conjugated linoleic acid (CLA) is one such intermediate, and the relationship between this isomer and a reduced milk fat output is well recognized. However, it was not known if these effects were direct or due to an intermediate produced in the metabolism of this CLA isomer. Therefore, an initial experiment provided the Delta6 desaturation product of trans-10, cis -12 CLA (cis-6, trans-10, cis-12 18:3) by abomasal infusion and it was demonstrated to not affect milk fat synthesis. These data substantiated a mechanism of action directly involving trans-10, cis-12 CLA, rather than one requiring metabolism of the isomer or the involvement of a downstream metabolite. Continuing research in the area of MFD has led investigators to suggest a role for other biohydrogenation intermediates in the regulation of milk fat synthesis. Candidate fatty acids whose increases were correlated with MFD were identified through a systematic and detailed sample analysis. Compounds that were tested for effects on milk fat in the dairy cow included: trans-8, cis-10 CLA, cis-9, trans-11 CLA, trans-10, trans-12 CLA and cis-11, trans-13 CLA. Despite the uptake and incorporation into milk fat of these CLA isomers by the mammary gland, none affected milk fat synthesis or any other variables related to milk production. The application of CLA as a management tool to induce a controlled reduction in milk fat production has been suggested and would require it to be in a form to avoid metabolism in the rumen. Amide-protected and lipid-encapsulated protection methods were tested for their ability to deliver trans -10, cis-12 CLA post-ruminally for absorption and subsequent regulation of milk fat. Incorporation of this CLA isomer into milk fat was determined to be similar for both supplements.
Download or read book Conjugated Linoleic Acid CLA and Milk Fat Synthesis in Dairy Cows written by Daniel Gunnar Peterson and published by . This book was released on 2003 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Conjugated Linoleic Acid Research written by Jean-Louis Sebedio and published by CRC Press. This book was released on 2020-03-05 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Conjugated Linoleic Acid Research, Volume 2 is the second book in a series devoted entirely to conjugated linoleic acid. This book has updated information on the analysis, biochemistry and applications of conjugated fatty acids in an attempt to make Volume 2, in conjunction with Volume 1 (published in 1999), the most comprehensive, up-to-date sources of CLA-related information available today. Both scientific and commercial views are presented, with the same data sometimes interpreted differently.
Download or read book Milk and Dairy Products in Human Nutrition written by Young W. Park and published by John Wiley & Sons. This book was released on 2013-04-09 with total page 1063 pages. Available in PDF, EPUB and Kindle. Book excerpt: Milk is nature’s most complete food, and dairy products are considered to be the most nutritious foods of all. The traditional view of the role of milk has been greatly expanded in recent years beyond the horizon of nutritional subsistence of infants: it is now recognized to be more than a source of nutrients for the healthy growth of children and nourishment of adult humans. Alongside its major proteins (casein and whey), milk contains biologically active compounds, which have important physiological and biochemical functions and significant impacts upon human metabolism, nutrition and health. Many of these compounds have been proven to have beneficial effects on human nutrition and health. This comprehensive reference is the first to address such a wide range of topics related to milk production and human health, including: mammary secretion, production, sanitation, quality standards and chemistry, as well as nutrition, milk allergies, lactose intolerance, and the bioactive and therapeutic compounds found in milk. In addition to cow’s milk, the book also covers the milk of non-bovine dairy species which is of economic importance around the world. The Editors have assembled a team of internationally renowned experts to contribute to this exhaustive volume which will be essential reading for dairy scientists, nutritionists, food scientists, allergy specialists and health professionals.
Download or read book Effects of Conjugated Linoleic Acids on Lipid Metabolism in Lactating Dairy Cows written by Lance Hall Baumgard and published by . This book was released on 2002 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Response of Milk Fat to Intravenous Administration of the Trans 10 Cis 12 Isomer of Conjugated Linoleic Acid CLA written by Srikant Viswanadha and published by . This book was released on 2000 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Endogenous Synthesis of Cis 9 Trans 11 Conjugated Linoleic Acid in the Lactating Dairy Cow written by Benjamin Alan Corl and published by . This book was released on 2003 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Acute Phase Proteins as Early Non Specific Biomarkers of Human and Veterinary Diseases written by Francisco Veas and published by BoD – Books on Demand. This book was released on 2011-10-10 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two volumes of Acute Phase Proteins book consist of chapters that give a large panel of fundamental and applied knowledge on one of the major elements of the inflammatory process during the acute phase response, i.e., the acute phase proteins expression and functions that regulate homeostasis. We have organized this book in two volumes - the first volume, mainly containing chapters on structure, biology and functions of APP, the second volume discussing different uses of APP as diagnostic tools in human and veterinary medicine.
Download or read book Role for Milk Enriched with Conjugated Linoleic Acid in Blood Lipids Body Weight and Composition in Moderately Overweight Hyperlipidemic Men and Women written by Sudha Venkatramanan and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Conjugated linoleic acid (CLA) reduces body weight and fat mass in animals. Human trials investigating effects of CLA on blood lipids, body weight and composition have shown inconsistent effects. The purpose of the present study therefore was to investigate effects of milk enriched with CLA on blood lipids -triglyceride (TG), total cholesterol (TC), low-density lipoprotein (LDL), high- density lipoprotein (HDL) cholesterol, body weight and body composition in moderately overweight, hyperlipidemic humans. Fifteen adult participants completed three 8-week dietary treatments in a crossover design. Treatments were: (i) control milk low in cis-9, trans-11 CLA (ii) milk naturally enriched with cis-9, trans-11 CLA, (iii) milk synthetically enriched with trans-10, cis-12 CLA and cis-9, trans-11 CLA. CLA did not affect blood lipid profile. No significant changes were observed in body weights and fat compartments with the CLA isomers. Thus CLA does not affect lipid profile, body weight and composition in moderately hyperlipidemic individuals." --
Download or read book Conjugated Linoleic Acids and Conjugated Vegetable Oils written by Bert Sels and published by Royal Society of Chemistry. This book was released on 2014-07-11 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conjugated linoleic acids (CLA) isomers of linoleic acid – a compound derived from meat and dairy products. Attention was first drawn to their potential anti-carcinogen properties in the 1980’s; since then further health benefits have been reported, and applications in the glue and paint industries as a renewable resource have been explored. This comprehensive book presents an overview of the background and research into CLA and examines each of their applications in the context of the chemistry surrounding them and CLA-enriched oils. The biosynthesis of CLA is presented, with a discussion on how animal husbandry could promote CLA production. Other chapters examine the current strategies for their synthesis using bespoke catalysts and enzymes. Readers from academia and industry will find the layout of the book highly accessible, with sections for each application. The editors are both active researchers in the field, and have brought together a wealth of expertise from across the globe, presenting a comprehensive guide to this valuable group of compounds and their potential applications.
Download or read book Nutrition in the Prevention and Treatment of Abdominal Obesity written by Ronald Ross Watson and published by Elsevier. This book was released on 2014-02-26 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrition in the Prevention and Treatment of Abdominal Obesity focuses on the important roles that exercise, dietary changes, and foods play in promoting as well as reducing visceral fat. Nutritionists, dieticians, and healthcare providers seeking to address the abdominal obesity epidemic will use this comprehensive resource as a tool in their long-term goal of preventing chronic diseases, especially heart, vascular, and diabetic diseases. Experts from a broad range of disciplines are involved in dealing with the consequences of excessive abdominal fat: cardiology, diabetes research, studies of lipids, endocrinology and metabolism, nutrition, obesity, and exercise physiology. They have contributed chapters that define a range of dietary approaches to reducing risk and associated chronic diseases. They begin by defining visceral obesity and its major outcomes; they also discuss the importance and the challenges of dietary approaches to reduce abdominal obesity, as compared to clinical approaches, with major costs and risks. Offers detailed, well-documented reviews outlining the various dietary approaches to visceral obesity with their benefits and failures Includes chapters on types of foods, exercise, and supplements in reducing obesity and its chronic clinical companions, especially diabetes and cardiovascular disease Helps nutritionists, dieticians, and healthcare providers approach patients in making decision about nutritional therapies and clinical treatments for abdominal obesity, from an evidence-based perspective
Download or read book Effects of Conjugated Linoleic Acid on Lipid Metabolism and Energy Balance in Dairy Cows written by Jane Kay and published by . This book was released on 2006 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three experiments were conducted with the goals to; 1) determine conjugated linoleic acid (CLA) effects on energy balance (EBAL) and milk production parameters during periods of nutrient/energy stress, and 2) investigate temporal CLA effects on mammary lipogenic gene expression. Study one was designed to determine if abomasal CLA infusion could reduce milk fat synthesis and partition nutrients towards alternative milk components in feed-restricted rotationally-grazed dairy cows. Data indicate abomasally-infusing CLA reduced milk fat synthesis in nutrient restricted grazing dairy cows and improved calculated EBAL and milk protein production. Another period of transitory stress experienced by the dairy cow is immediately postpartum and study two objectives were to feed rumen inert-CLA to evoke milk fat depression (MFD) and investigate production and bioenergetic parameters. Data indicated a high CLA dose (3x that needed in established lactation) inhibited milk fat synthesis immediately postpartum and improved calculated EBAL in grazing dairy cows. A curvilinear relationship existed between the extent of CLA-induced MFD and milk yield response. Moderate CLA-induced MFD (3̃5%) tended to increase milk yield whereas extensive MFD (3̃5%) diminished this response. Additionally, SCD inhibition was temporally independent indicating SCD activity and membrane fluidity are not the reason for diminished milk yield effects. Furthermore, data indicate that de novo fatty acids and trans-10, cis-12 CLA content don't appreciably change during early lactation, even though the extent of MFD increased, indicating neither NEFA competition nor de novo fatty acid contribution are primary reasons for reduced CLA-mammary sensitivity. Study three investigated intravenous CLA infusion effects on temporal mammary lipogenic gene expression to determine if trans-10, cis-12 CLA down regulates expression of a key gene (i.e. acetyl CoA carboxylase, ACC, the rate limiting enzyme in de novo fatty acid synthesis) and reduction in other mammary lipid synthesis genes is due to lack of substrate (i.e. malonyl CoA), or an alternative indirect mechanism. Data indicated however, that mammary lipogenic genes (ACC, fatty acid synthetase and SCD) followed a similar temporal pattern, providing more support for a global regulator (i.e. sterol regulatory element binding protein-1, peroxisome proliferator-activated receptor- or nuclear factor-B) rather than a specific key enzyme effect.
Download or read book Advances in Conjugated Linoleic Acid Research Volume 3 written by Martin P. Yurawecz and published by The American Oil Chemists Society. This book was released on 2006-09-29 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in the chemistry, biological properties and healthful benefits of conjugated linoleic acid (CLA) continues to grow. The number of peer reviewed publications produced on CLA since the 2003 publication of Advances in Conjugated Linoleic Acid Research, Volume 2, has more than doubled. It is likely that CLA will be used in the future in many more studies related to diseases such as cancer, atherosclerosis, and diabetes. This text provides comprehensive coverage of this area of research. Sections include material on biosynthesis and metabolic processes, techniques of determination of individual isomers, diversity of CLA, and effects of CLA isomers in humans.
Download or read book Polyunsaturated Fatty Acid Metabolism written by Graham C. Burdge and published by Elsevier. This book was released on 2018-05-04 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyunsaturated Fatty Acid Metabolism explores a number of major roles of PUFA in the body, including its role as a component of cell membranes and how it provides substrates for the synthesis of lipid second messengers. Recent studies are unraveling the effect of interactions between diet and endocrine factors and genetic and epigenetic variation on the regulation of PUFA biosynthesis in animals. Together, these recent findings provide novel insights into the impact of differences in PUFA supply on health. This book captures these findings in a manner that marks the state-of-the-art, placing them in the wider context of PUFA metabolism and nutritional science. Users will find a comprehensive discussion on the topic that presents the contributions of leading researchers who combine their knowledge to create a cohesive academic resource for researchers, those involved in production, and health policymakers. Provides a comprehensive view of polyunsaturated fatty acid metabolism Describes underlying metabolism on lipids that include polyunsaturated fatty acids Includes discussions on recent findings on the genetic and epigenetic regulation of polyunsaturated fatty acid metabolism
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2006 with total page 854 pages. Available in PDF, EPUB and Kindle. Book excerpt:
