Download or read book Role of Cell Adhesion Molecule in Lung Cancer Metastasis written by 楊泮池 and published by . This book was released on 1998 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cell Adhesion and Cytoskeletal Molecules in Metastasis written by Anne E. Cress and published by Springer Science & Business Media. This book was released on 2007-01-20 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume highlights the expression of specific adhesion molecules within human cancer tissues. It details the expression signatures from published DNA microarray and immunohistochemistry studies. Coverage discusses the concept that the alteration of specific adhesion molecules influence the cancer migration ability and cancer damage responses, both features are essential for the survival of an invading tumor cell.
Download or read book Cell Adhesion Molecules in Cancer and Inflammation written by Agamemnon A. Epenetos and published by CRC Press. This book was released on 1995-06-01 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Begins a series for clinicians, graduate students, and researchers in academia, regulatory agencies, or industry, offering monographs both on classes of adhesion molecules and on the function of such molecules in particular systems. Here the emphasis is on the clinical evaluation of these molecules, particularly as novel biochemical and genetic markers to define tumor differentiation based on functional and morphological assessment, and also their potential use as targets for biological therapy. Includes ten pages of color plates. Annotation copyright by Book News, Inc., Portland, OR
Download or read book Adhesion Molecules and the Lung written by P. A. Ward and published by CRC Press. This book was released on 1996-01-23 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This state-of-the-art reference outlines current knowledge of the structure, transcriptional regulation, and binding characteristics of vascular and leukocyte adhesion molecules and their ligands delineating the nature of adhesion molecule interactions in lung morphogenesis and repair, tumor metastasis, and experimental models of inflammatory lung injury.
Download or read book Cell Adhesion Molecules written by Martin E. Hemler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fourth Annual Pezcoller Symposium entitled Adhesion Molecules: Cellular Recognition Mechanisms was held in Rovereto, Italy, June 24-26, 1992 and was focussed on the detailed mechanisms whereby cells utilize certain integral membrane proteins to perceive their surrounding environment and interact with it. With timely presentations and stimulating discussions this Symposium addressed the genetics and biochemistry of adhesion molecules, the regulation of their functions and their role in cancer and the immune system. Emphasis was given to adhesion proteins in the integrin family because of the widespread distribution of this group of molecules and its important role in essentially all eukaryotic biological systems. The regulation of integrin genes and their expression are discussed in detail, as are specific aspects of the genetics of fibronectin. The molecular basis for the regulation of certain integrins, the function of these proteins in determining cell adhesion, and the consequences of this adhesion for the function of the cells involved are discussed. The role of certain integrins in stimulating signal transduction, the essential involvement of integrins in conditioning the function of T and NK cells function, the heterogeneity of integrins and its biological consequences, and the role of cell adhesion molecules in tumor cells invasion and metastases are all extensively analyzed. New information was presented on the role of CD44 and splice variants in normal differentiation and tumor progression.
Download or read book Cell Adhesion and Invasion in Cancer Metastasis written by Pnina Brodt and published by New York : Springer. This book was released on 1996-01-01 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: A critical review of the latest research on the specific cell adhesion molecules involved in the metastatic process. After a summary of concepts in the field, chapters detail findings on the molecular biology and biochemistry of adherins, integrins, selectins and their ligands, and the Ig-like adhesion family, and review the role of proteases and protease inhibitors in regulating the metastatic process and modulating cell adhesion. Includes material on current methods for the analysis of cell invasion. Of interest to novices and experts in tumor biology. Annotation copyright by Book News, Inc., Portland, OR
Download or read book Metastasis From Cell Adhesion and Beyond written by Vasiliki Gkretsi and published by Frontiers Media SA. This book was released on 2019-08-22 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook consists of a collection of articles focused on fundamental processes of cancer cell metastasis, such as cell-Extracellular matrix adhesions, epithelial-to-mesenchymal transition (EMT) and lymph node metastasis as well as on upcoming research fields including the effects of biomechanical factors, the use of analytical and statistical tools and experimental techniques to further understand and characterize the invasive and metastatic potential of tumors.
Download or read book Cell Cell and Cell Matrix Adhesion in Immunobiology and Cancer written by Toshiyuki Murai and published by Frontiers Media SA. This book was released on 2020-02-19 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Download or read book An Investigation of the Biological Role of the Neural Cell Adhesion Molecule in Lung Cancer and Its Clinical Potential as a Target for Antibody directed Therapy written by and published by . This book was released on 1999 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cancer Metastasis Molecular and Cellular Mechanisms and Clinical Intervention written by Wen G. Jiang and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the molecular and cellular aspects of cancer metastasis, and discusses the clinical aspect of micro- and macro-metastases, which result in the death of the majority of patients with cancer. The current edition attempts to examine the current status of the basic scientific and clinical research in the area, and is a very useful reference for clinicians, oncologists, and biologists. It is intended for undergraduates as well as postgraduates in the area of medicine, oncology, and cancer biology.
Download or read book Lung Endothelial Cell Adhesion Molecules which Mediates Organ specific Vascular Arrest of Lung Metastatic Cells written by Robert C. Johnson and published by . This book was released on 1992 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanisms of Invasion and Metastasis written by Marc M. Mareel and published by CRC Press. This book was released on 1991-04-23 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers important biological, immunological, and molecular information essential for understanding the rationale and results of experiments and clinical observations on cell-cell and cell substrate adhesion; hydrolytic activities, cell motility; immunological and other host elements of the host-tumor ecosystem (at different sites of the metastic process); genetic and epigenetic elements of the acquisition and the expression of invasive phenotypes. 38 tables and 60 computer-drawn figures provide comprehensive overviews, and a methodological chapter emphasizing the differences and similarities between assays and their relevance for natural situations has also been included. Clinical and experimental cancer researchers, as well as as post-graduate students interested in cancer research, will find this book to be an indispensable reference resource.
Download or read book Pulmonary Metastasis written by Leonard Weiss and published by Macmillan Reference USA. This book was released on 1978 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Attempts to Understand Metastasis Formation I written by Ursula Günthert and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: In metastasis, tumor cells disseminate from the primary lesion and home to secondary organs where they may remain dormant for a long time. Metastasis formation is still the most feared manifestation for tumor patients and clinicians. Although improvements have been made concerning earlier detection and specific therapy, most of the cancer patients still die of distant metastases. The pu-rpose of these three volumes is to review the recent progress in molecular metas tasis research and to attempt to further understand the biol ogy of this multifocal process. With respect to present day molecular biology, the pioneers of metastasis research established the basic concepts of metasta sis formation in the 1970s and 1980s, namely, clonal selection of metastatic cells, heterogeneity of metastatic subpopulations, organ specificity of metastasis and the importance of angio genesis (Fidler, Kripke, Nicolson, Folkman and others). In the 1980s and 1990s, several of the molecules involved were identified and their network interactions elucidated. These three volumes of Current Topics in Microbiology and Immuno logy compile the most recent developments on these meta stasis-related molecules; their interactions, regulation, and ways to interfere with their action. It became evident that metastasis-related molecules are confined to distinct cellular compartments, such as the extracellular space, the cell membrane, the cytoplasmic signalling network, and the nuclear regulatory system. For the complex metastatic cascade, proteolysis and alterations in adhesive functions are the most obvious and thus one of the most thoroughly investigated processes.
Download or read book Cell Adhesion Molecules and Matrix Proteins written by Shaker A. Mousa and published by . This book was released on 1998 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Lung Cancer Metastasis written by Venkateshwar Keshamouni and published by Springer Science & Business Media. This book was released on 2009-09-18 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lung cancer is the leading cause of cancer-related mortality. Metastatic lung cancer is responsible for more than ninety percent of lung cancer related deaths. However, relatively little progress has been made in understanding the process of lung cancer metastasis. The two main aims of this book are a) to introduce clinical aspects to basic scientists and basic molecular and cellular concepts to clinical investigators, in order to promote collaboration and foster much needed translational research; and b) to introduce new and emerging concepts and approaches in metastasis research to lung cancer research community at large. In this attempt, the book will cover a broad spectrum of subjects ranging from the current trends in the clinical management of the metastatic disease, to the systems biology approach for gaining insights into the mechanisms of metastasis. Some of the subjects covered will include: defining basic hallmarks of a metastatic cell, the concept of tumor stem cells, epithelial-mesenchymal transitions, evasion of immune-surveillance, tumor-stromal interactions, angiogenesis, molecular imaging and biomarker discovery.
Download or read book Research on Melanoma written by Mandi Murph and published by BoD – Books on Demand. This book was released on 2011-09-12 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book Research on Melanoma: A Glimpse into Current Directions and Future Trends, is divided into sections to represent the most cutting-edge topics in melanoma from around the world. The emerging epigenetics of disease, novel therapeutics under development and the molecular signaling aberrations are explained in detail. Since there are a number of areas in which unknowns exist surrounding the complex development of melanoma and its response to therapy, this book illuminates and comprehensively discusses such aspects. It is relevant for teaching the novice researcher who wants to initiate projects in melanoma and the more senior researcher seeking to polish their existing knowledge in this area. Many chapters include visuals and illustrations designed to easily guide the reader through the ideas presented.
