Download or read book Risk Factors for Adverse Drug Reactions written by Rolf Hoigné and published by Birkhauser. This book was released on 1990 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pharmacokinetics and Adverse Effects of Drugs written by Ntambwe Malangu and published by BoD – Books on Demand. This book was released on 2018-05-23 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a fruit of a collaborative work from several international scientists. It will be a useful resource for researchers, students, and clinicians. Each individual chapter could serve as a prescribed reading for postgraduate students and clinicians specializing in and practicing clinical pharmacology and toxicology, pharmacotherapy and pharmacotherapeutics, pharmacovigilance, and toxicovigilance, as well as those involved in clinical research, drug discovery, and development. Every chapter in this book discusses and provides illustrations on the theme discussed based on authors' understanding and experience while summarizing existing knowledge. In doing so, each chapter provides a new insight that would benefit a novice as well as a seasoned reader in understanding the pharmacokinetic mechanisms and risk factors involved in the occurrence of adverse effects of drugs.
Download or read book Risk Factors for Adverse Drug Reactions Epidemiological Approaches written by Weber and published by Birkhäuser. This book was released on 1990-01-01 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: The benzodiazepines are among the most widely-used of drugs. However, in many countries their popularity is waning as prescribers become more aware of problems with unwanted effects and with rebound and withdrawal syndromes. The earlier benzodiazepines were long-acting, and it was thought that their shorter-acting successors would have important advantages. Other developments include partial agonists and partial inverse agonists, compounds acting on the benzodiazepine-GABA macro molecular site although not as a typical benzodiazepine, and anxiolytic agents acting on 5-HT pathways directly. I shall review the problems of unwanted effects and dependence, mainly from an epidemiological view point, and then relate the pharmacological properties of the newer com pounds to possible differences in their clinical profile of adverse effects. Adverse behavioural effects Benzodiazepines are used, inter alia, as anxiolytics and hyp notics. The latter use exploits the sedative actions which occur at higher than anxiolytic doses. The sedation should disappear by the time the patient wakes up. Hypnotics are thus unique in that their wanted effect and unwanted effect are identical - sedation - but separated in time by about 8 hours.
Download or read book Risk Factors for Adverse Drug Reactions Epidemiological Approaches written by Weber and published by Birkhäuser. This book was released on 2014-01-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The benzodiazepines are among the most widely-used of drugs. However, in many countries their popularity is waning as prescribers become more aware of problems with unwanted effects and with rebound and withdrawal syndromes. The earlier benzodiazepines were long-acting, and it was thought that their shorter-acting successors would have important advantages. Other developments include partial agonists and partial inverse agonists, compounds acting on the benzodiazepine-GABA macro molecular site although not as a typical benzodiazepine, and anxiolytic agents acting on 5-HT pathways directly. I shall review the problems of unwanted effects and dependence, mainly from an epidemiological view point, and then relate the pharmacological properties of the newer com pounds to possible differences in their clinical profile of adverse effects. Adverse behavioural effects Benzodiazepines are used, inter alia, as anxiolytics and hyp notics. The latter use exploits the sedative actions which occur at higher than anxiolytic doses. The sedation should disappear by the time the patient wakes up. Hypnotics are thus unique in that their wanted effect and unwanted effect are identical - sedation - but separated in time by about 8 hours.
Download or read book Fundamentals of Pediatric Drug Dosing written by Iftekhar Mahmood and published by Springer. This book was released on 2016-10-28 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focused on pediatric physiology, pharmacology, pharmacokinetics and pharmacodynamics, this book illustrates the differences between the pediatric population and adults; knowledge of extreme importance not only during pediatric drug development but also in the clinical practice. Physicians, nurses, clinical pharmacologists, researchers and healthcare professionals will find this an invaluable resource. With the advent of pediatric exclusivity, and requirements to conduct clinical studies in children, an emphasis has been placed on finding a safe and efficacious dose of a drug in children. Children are not ‘small adults’, and drug dosing in this population requires special consideration. There are subtle physiological and biochemical differences among neonates, infants, children, adolescents and adults and dosing in pediatrics requires proper understanding of these factors. Furthermore, dosing in children, as in adults, should be based on pharmacokinetic and pharmacodynamic data. This is an evolving area, as pediatric pharmacokinetic studies are becoming mandatory for getting approval of new drugs in this population.
Download or read book Adverse Drug Reactions written by Anne Lee and published by Pharmaceutical Press. This book was released on 2006 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adverse reactions to medicines continue to present a burden on healthcare, causing considerable morbidity and mortality. Aswell as knowing about the benefits of medicines, healthcare professionals need to understand the problem of adverse drugreactions and be aware of how they can be prevented and managed. This essential and practical guide has been extensively revised and updated to include three new chapters on adverse effectsof drugs in pregnancy, pharmacogenetics, and side effects and patients. Case studies are provided with each chapter.
Download or read book Potential Risk Factors for Adverse Drug Reactions in Elderly Patients written by Sabin Séverine Egger and published by . This book was released on 2007 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Patient Safety written by Kerm Henriksen and published by . This book was released on 2005 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: v. 1. Research findings -- v. 2. Concepts and methodology -- v. 3. Implementation issues -- v. 4. Programs, tools and products.
Download or read book Risk Factors Associated with Adverse Drug Events Among a High Risk Outpatient Population written by Xiaoyan Ying and published by . This book was released on 2007 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Detection of New Adverse Drug Reactions written by M. D. B. Stephens and published by Springer. This book was released on 1985-06-18 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Registries for Evaluating Patient Outcomes written by Agency for Healthcare Research and Quality/AHRQ and published by Government Printing Office. This book was released on 2014-04-01 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.
Download or read book Stephens Detection and Evaluation of Adverse Drug Reactions written by John Talbot and published by John Wiley & Sons. This book was released on 2011-10-28 with total page 751 pages. Available in PDF, EPUB and Kindle. Book excerpt: The detection and evaluation of adverse drug reactions is crucial for understanding the safety of medicines and for preventing harm in patients. Not only is it necessary to detect new adverse drug reactions, but the principles and practice of pharmacovigilance apply to the surveillance of a wide range of medicinal products. Stephens' Detection and Evaluation of Adverse Drug Reactions provides a comprehensive review of all aspects of adverse drug reactions throughout the life cycle of a medicine, from toxicology and clinical trials through to pharmacovigilance, risk management, and legal and regulatory requirements. It also covers the safety of biotherapeutics and vaccines and includes new chapters on pharmacogenetics, proactive risk management, societal considerations, and the safety of drugs used in oncology and herbal medicines. This sixth edition of the classic text on drug safety is an authoritative reference text for all those who work in pharmacovigilance or have an interest in adverse drug reactions, whether in regulatory authorities, pharmaceutical companies, or academia. Praise for previous editions "This book presents a comprehensive and wide-ranging overview of the science of pharmacovigilance. For those entering or already experienced in the pharmaceutical sciences, this is an essential work.” - from a review in E-STREAMS "...a key text in the area of pharmacovigilance...extensively referenced and well-written...a valuable resource..." - from a review in The Pharmaceutical Journal
Download or read book Side Effects of Drugs Annual written by J. K. Aronson and published by Elsevier. This book was released on 2011-12-20 with total page 1152 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Provides clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of adverse drug reactions and interactions."--Publisher.
Download or read book It All Depends on the Dose written by Ole Peter Grell and published by Routledge. This book was released on 2018-05-11 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first volume to take a broad historical sweep of the close relation between medicines and poisons in the Western tradition, and their interconnectedness. They are like two ends of a spectrum, for the same natural material can be medicine or poison, depending on the dose, and poisons can be transformed into medicines, while medicines can turn out to be poisons. The book looks at important moments in the history of the relationship between poisons and medicines in European history, from Roman times, with the Greek physician Galen, through the Renaissance and the maverick physician Paracelsus, to the present, when poisons are actively being turned into beneficial medicines.
Download or read book Guidelines for the Programmatic Management of Drug Resistant Tuberculosis written by World Health Organization and published by . This book was released on 2015-04-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 2011 update of Guidelines for the programmatic management of drug-resistant tuberculosis is intended as a tool for use by public health professionals working in response to the Sixty-second World Health Assembly's resolution on prevention and control of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis. Resolution WHA62.15, adopted in 2009, calls on Member States to develop a comprehensive framework for the management and care of patients with drug-resistant TB. The recommendations contained in these guidelines address the most topical questions concerning the programmatic management of drug-resistant TB: case-finding, multidrug resistance, treatment regimens, monitoring the response to treatment, and selecting models of care. The guidelines primarily target staff and medical practitioners working in TB treatment and control, and partners and organizations providing technical and financial support for care of drug-resistant TB in settings where resources are limited.
Download or read book Further Studies Upon the Phenomenon of Anaphylaxis written by Milton Joseph Rosenau and published by . This book was released on 1909 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Prescribed Medications and the Public Health written by William N. Kelly and published by CRC Press. This book was released on 2006-07-28 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: An alarming look at America’s other drug problem—medication safety! Drug misadventures are an all-too-frequent and deadly cause of adverse medical events. Prescribed Medications and the Public Health: Laying the Foundation for Risk Reduction explores ways to combat the widespread problem of adverse drug events (ADEs). This comprehensive book shows how our broken health care and medication use system often inflicts harm—most of it preventable—on patients. Strategies are presented to help health care managers, health professionals, regulators, and policymakers to dynamically improve the entire system. With the growing use of prescribed medications comes a rising number of adverse drug reactions, drug interactions, allergic reactions, and medication errors. Prescribed Medications and the Public Health discusses problems such as drug supply issues, drug defects, counterfeit drugs, limitations for oversight of Internet prescriptions, inaccurate splitting of pills, and poor administration of drugs. The book examines the issues from all angles, including patient considerations, drug factors, and unsafe practices that contribute to ADEs. Liability costs for drug injury are reviewed, along with effective practical strategies for preventing, reducing, detecting, and documenting adverse drug events. National and local plans are explored to help achieve the essential goal of greater safety throughout the system. The text is extensively referenced and includes approximately 50 figures and tables to clearly present information. Prescribed Medications and the Public Health reviews in detail how to battle these problems in both inpatient and ambulatory care: adverse drug reactions dangerous allergic reactions harmful drug interactions medication errors adverse vaccine reactions drug misadventures Prescribed Medications and the Public Health is crucial reading for medication safety officers; pharmacoepidemiologists; medication safety experts; educators and students in schools of pharmacy and public health, medicine, nursing, and hospital/health services management; health care managers; regulators; policymakers; and advocates for improving drug safety.
