Download or read book Handbook of Validation in Pharmaceutical Processes Fourth Edition written by James Agalloco and published by CRC Press. This book was released on 2021-10-28 with total page 1062 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revised to reflect significant advances in pharmaceutical production and regulatory expectations, Handbook of Validation in Pharmaceutical Processes, Fourth Edition examines and blueprints every step of the validation process needed to remain compliant and competitive. This book blends the use of theoretical knowledge with recent technological advancements to achieve applied practical solutions. As the industry's leading source for validation of sterile pharmaceutical processes for more than 10 years, this greatly expanded work is a comprehensive analysis of all the fundamental elements of pharmaceutical and bio-pharmaceutical production processes. Handbook of Validation in Pharmaceutical Processes, Fourth Edition is essential for all global health care manufacturers and pharmaceutical industry professionals. Key Features: Provides an in-depth discussion of recent advances in sterilization Identifies obstacles that may be encountered at any stage of the validation program, and suggests the newest and most advanced solutions Explores distinctive and specific process steps, and identifies critical process control points to reach acceptable results New chapters include disposable systems, combination products, nano-technology, rapid microbial methods, contamination control in non-sterile products, liquid chemical sterilization, and medical device manufacture

Download or read book Complete Guide to Federal and State Garnishment 2019 Edition IL written by Bryant and published by Wolters Kluwer. This book was released on 2018-12-19 with total page 1290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complete Guide to Federal and State Garnishment provides much-needed clarity when the federal and state laws appear to conflict. You'll find plain-English explanations of the laws and how they interact, as well as the specific steps you and your staff need to take to respond to the order properly. Numerous detailed examples and mathematical calculations make it easy to apply the law under different scenarios. Written by Amorette Nelson Bryant, who was recently appointed by the Uniform Law Commission as an observer for the Drafting Committee on a Wage Garnishment Act and was a past chair of both the APA GATF Child Support Subcommittee and Garnishment Subcommittee, Complete Guide to Federal and State Garnishment brings the payroll professional up-to-date on the latest federal and state laws and regulations affecting this ever-changing area. It is your one-stop source for answers to critical questions, such as: Does the amount exempt from garnishment change when the minimum wage goes up? How do I determine the wages to which the garnishment applies? If an employee is subject to more than one garnishment, which has priority? Which state's rules do I use when I receive a child support order sent from another state? State or federal law - which applies for creditor garnishment and support? Are there alternatives to remitting withheld child support via EFT/EDI? How do I handle garnishments when employees are paid a draw against salary? Previous Edition: Complete Guide to Federal and State Garnishment, 2018 Edition, ISBN 9781454884255¿

Download or read book Toxicological Risk Assessment and Multi System Health Impacts from Exposure written by Aristidis M. Tsatsakis and published by Elsevier. This book was released on 2021-08-01 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants. The book describes the cellular, biological, immunological, endocrinologic, genetic, and epigenetic effects of long-term exposure. It examines how the combined exposure to nanomaterials, metals, pharmaceuticals, multifrequency radiation, dietary mycotoxins, and pesticides accelerates ecotoxicity in humans, animals, plants, and the larger environment. The book goes on to also offer insights into mixture risk assessments, protocols for evaluating the risks, and how this information can serve the regulatory agencies in setting safer exposure limits. The book is a go-to resource for scientists and professionals in the field tackling the current and emerging trends in modern toxicology and risk assessment. - Bridges basic research with clinical, epidemiological, regulatory, and translational research, conveying both an introductory understanding and the latest developments in the field - Evaluates real-life human health risk assessment for long-term exposures to xenobiotic mixtures and the role they play in contributing to chronic disease - Discusses advances in predictive (in silico) toxicology tools and the benefits of using omics technologies in toxicology research

Download or read book ICREEM 2022 written by Faiz Ahmad and published by Springer Nature. This book was released on with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Complete Guide to Personal Training written by Morc Coulson and published by Bloomsbury Publishing. This book was released on 2024-10-10 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: A revised and updated third edition of the popular Complete Guide to Personal Training with up-to-date content and new exercises. This is the complete reference guide for anyone working as a personal trainer, or studying to become one, with an in-depth look into the role of the trainer in relation to codes of conduct and client care. This comprehensive book contains practical tips and advice for designing a range of exercise programmes for clients. It also focuses on the best ways to sustain a financially successful personal training business and stand out from the crowd. This new third edition includes: - Brand-new illustrated stretches and exercises - Advice on training at home or outdoors - A spotlight on client well-being - Updated government guidelines, statistics and scientific findings - Guidance on adapting exercises for disabled or vulnerable clients - National guidelines for nutrition and weight. This is essential reading for personal trainers in the health and fitness industry and for those teaching or studying for qualifications in this area.

Download or read book Underwater Inspection and Repair for Offshore Structures written by John V. Sharp and published by John Wiley & Sons. This book was released on 2021-04-01 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: UNDERWATER INSPECTION AND REPAIR FOR OFFSHORE STRUCTURES Benefit from a much-needed, up-to-date handbook on underwater inspection and repair processes and technologies Underwater Inspection and Repair for Offshore Structures fills a gap in the literature to provide an overview of the inspection and repair processes for both steel and concrete offshore structures. Authors and noted experts on the topic John V. Sharp and Gerhard Esdal guide readers through the reasons why inspection and repair are performed and how both are linked to the management of structural integrity, statutory requirements, and various types of damage. The book addresses critical topics, including the execution and planning of inspection and repair, the tools and methods used, and their deployment underwater. The authors put particular focus on steel and concrete offshore oil and gas installations, but the content is also applicable to the substructures of offshore wind turbines. Underwater Inspection and Repair for Offshore Structures is complementary to the authors’ book Ageing and Life Extension of Offshore Structures, also from Wiley. This important book: Covers current inspection and monitoring techniques to evaluate existing structures Includes coverage of robotic (ROV) inspection and repair methods Provides an overview of repair and maintenance techniques applicable to the splash‐zone and underwater operations Written for engineers, designers, and safety auditors working with offshore structures. Underwater Inspection and Repair for Offshore Structures is a comprehensive resource for understanding how to effectively inspect and repair these vulnerable structures.

Download or read book WHO benchmarks for strengthening health emergency capacities written by World Health Organization and published by World Health Organization. This book was released on 2024-01-25 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: The WHO Benchmarks for International Health Regulations (2005) (IHR) Capacities was first published in 2019 and serves as a capacity-building tool and reference document to guide development/updating of country health security plans, including the national action plan for health security (NAPHS). It is now updated to a second edition which incorporates lessons learned from recent health emergencies, as well as alignment with updated IHRMEF tools, the HEPR framework, the WHO Director-General’s ten proposals to build a safer world together, and to build back better through multi-hazard and whole-of-society approaches to support better preparedness for future emergencies. Over 250 relevant technical leads contributed to this edition, by providing inputs from WHO regional offices, countries, partners and participation in global consultation meetings. The second edition is titled “WHO Benchmarks for Strengthening Health Emergency Capacities: Support for the Implementation of International Health Regulations (IHR) and Health Emergency Prevention, Preparedness, Response and Resilience (HEPR) Capacities”. WHO benchmarks are further digitalized for easy and quick use, along with a reference library, which is currently being updated. The audience for this document includes WHO Member States, health ministries and other relevant ministries, healthstakeholders, partners, nongovernmental organizations and academia to support building capacities at the country level.

Download or read book The Governance of Regulators Progress Review of Peru s Telecommunications Regulator Driving Performance written by OECD and published by OECD Publishing. This book was released on 2023-04-12 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regulators act as “market referees”, balancing often competing interests of stakeholders, including governments, current and future actors in the markets, and consumers. At the same time, markets are changing at an unprecedented pace due to new technologies, the international drive toward carbon-neutral economies, shifts in consumer needs and preferences, and, more recently, the profound changes brought by the COVID-19 pandemic.

Download or read book Shrimp acute hepatopancreatic necrosis disease strategy manual written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2020-11-24 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contents of this Shrimp acute hepatopancreatic necrosis disease strategy manual provides information and guidance relevant to the development of policies to respond to outbreaks of acute hepatopancreatic necrosis disease (AHPND) in farmed marine shrimp. The etiologic agents for AHPND are virulent strains of bacteria belonging to the genus Vibrio parahaemolyticus and related species, which harbor specific toxin genes. While these bacterial species are part of the normal microflora of the marine environment, they may cause substantial mortalities in whiteleg shrimp (Penaeus vannamei) and giant tiger prawn (Penaeus monodon) cultured in countries in Asia and the Americas. These strains of these Vibrio bacteria secrete a PirABvp binary toxin resulting in sloughing of tubule epithelial cells and dysfunctions of the hepatopancreas in the acute form; mortality can reach 100 percent in affected ponds. Chronic presentation of this disease involves secondary bacterial infection of hepatopancreas and running mortality over the culture cycle. Acute or chronic presentation would greatly depend on the culture conditions. This disease can be considered a toxicosis rather than an infection. Economic losses due to this disease have amounted to over USD 7 billion annually. Further outbreaks of AHPND, particularly in areas that are currently free of the disease, would be expected to experience similar devastating effects on local shrimp producers and the surrounding communities; and thus, there is an urgent need to develop a contingency plan to control and eradicate this disease. This manual includes information on: 1) the nature of AHPND: a brief review of current knowledge in disease etiology, susceptible species and global distribution; 2) diagnosis of disease: a description of gross clinical signs and laboratory methods; 3) prevention and treatment: farm management, the use and development of antibiotics, bacteriophages, probiotics, disease-tolerant shrimp, shrimp immunity and vaccination; 4) epidemiology: AHPND’s geographic distribution, genotype, persistence in the environment, reservoir hosts, modes of transmission, risk factors, and economic impacts; 5) principles of control and eradication: methods for containment, mitigation and eradication of AHPND, and trade and industry considerations; and 6) policy development and implementation: AHPND-specific objectives, options and strategies for eradication and control, education, capacity building, funding, and compensation.

Download or read book The Combination Products Handbook written by Susan Neadle and published by CRC Press. This book was released on 2023-05-16 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combination products are therapeutic and diagnostic products that combine drugs, devices, and/or biological products. According to the US Food and Drug Administration (FDA), “a combination product is one composed of any combination of a drug and a device; a biological product and a device; a drug and a biological product; or a drug, device and a biological product.” Examples include prefilled syringes, pen injectors, autoinjectors, inhalers, transdermal delivery systems, drug-eluting stents, and kits containing drug administration devices co-packaged with drugs and/or biological products. This handbook provides the most up-to-date information on the development of combination products, from the technology involved to successful delivery to market. The authors present important and up-to-the-minute pre- and post-market reviews of international combination product regulations, guidance, considerations, and best practices. This handbook: Brings clarity of understanding for global combination products guidance and regulations Reviews the current state-of-the-art considerations and best practices spanning the combination product lifecycle, pre-market through post-market Reviews medical product classification and assignment issues faced by global regulatory authorities and industry The editor is a recognized international Combination Products and Medical Device expert with over 35 years of industry experience and has an outstanding team of contributors. Endorsed by AAMI – Association for the Advancement of Medical Instrumentation.

Download or read book Guidelines for Risk Based Process Safety written by CCPS (Center for Chemical Process Safety) and published by John Wiley & Sons. This book was released on 2011-11-30 with total page 759 pages. Available in PDF, EPUB and Kindle. Book excerpt: Guidelines for Risk Based Process Safety provides guidelines for industries that manufacture, consume, or handle chemicals, by focusing on new ways to design, correct, or improve process safety management practices. This new framework for thinking about process safety builds upon the original process safety management ideas published in the early 1990s, integrates industry lessons learned over the intervening years, utilizes applicable "total quality" principles (i.e., plan, do, check, act), and organizes it in a way that will be useful to all organizations - even those with relatively lower hazard activities - throughout the life-cycle of a company.

Download or read book Beginner eguide for food estartup written by CA Pulkit Gupta and published by E-Startup India. This book was released on 2019-12-10 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food business operating at small scale, i.e. having annual turnover below 12 lakhs requires FSSAI registration.FSSAI license is required by food business who oprates at large scale. FSSAI license further categorized in two parts i.e. State and Central license. To know more: https://www.e-startupindia.com/fssai-registration.html

Download or read book Ageing and Life Extension of Offshore Structures written by Gerhard Ersdal and published by John Wiley & Sons. This book was released on 2019-02-04 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of managing and assessing safety and functionality of ageing offshore structures and pipelines A significant proportion, estimated at over 50%, of the worldwide infrastructure of offshore structures and pipelines is in a life extension phase and is vulnerable to ageing processes. This book captures the central elements of the management of ageing offshore structures and pipelines in the life extension phase. The book gives an overview of: the relevant ageing processes and hazards; how ageing processes are managed through the life cycle, including an overview of structural integrity management; how an engineer should go about assessing a structure that is to be operated beyond its original design life, and how ageing can be mitigated for safe and effective continued operation. Key Features: Provides an understanding of ageing processes and how these can be mitigated. Applies engineering methods to ensure that existing structures can be operated longer rather than decommissioned unduly prematurely. Helps engineers performing these tasks in both evaluating the existing structures and maintaining ageing structures in a safe manner. The book gives an updated summary of current practice and research on the topic of the management of ageing structures and pipelines in the life extension phase but also meets the needs of structural engineering students and practicing offshore and structural engineers in oil & gas and engineering companies. In addition, it should be of value to regulators of the offshore industry.

Download or read book Connecting with Upstream Oil and Gas written by J Denver Smart and published by J. Denver Smart. This book was released on 2019-06-24 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sales and marketing professionals servicing the upstream oil and gas sector want to know their customer, but in an industry so complex, that is not always easy. J. Denver Smart provides a consolidated resource guide of upstream processing, key operations, and business drivers that are relevant to day-to-day operator challenges. It is specifically written to enable upstream product and service providers to identify the unique business value of their solutions. Topics covered include: • the primary market drivers and business parameters that affect the short- and long-term economic viability of upstream operators; • market indicators used to assess current and regional industry trends; • various lifecycle stages of an oilfield and their influence on primary business objectives; and • basic elements, principles, operations, and procedures associated with finding, extracting, and producing oil and gas reserves. The guide represents fifteen years’ experience in targeting and enabling sales and marketing teams globally to drive incremental growth opportunities in the upstream industry. The content structure, root-cause problem profiles, and cause-and-effect summaries support collaborative problem solving, identifying solution value, and the development of engaging content marketing.

Download or read book The Complete Guide to Business Risk Management written by Kit Sadgrove and published by Routledge. This book was released on 2020-07-26 with total page 743 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk management and contingency planning has really come to the fore since the first edition of this book was originally published. Computer failure, fire, fraud, robbery, accident, environmental damage, new regulations - business is constantly under threat. But how do you determine which are the most important dangers for your business? What can you do to lessen the chances of their happening - and minimize the impact if they do happen? In this comprehensive volume Kit Sadgrove shows how you can identify - and control - the relevant threats and ensure that your company will survive. He begins by asking 'What is risk?', 'How do we assess it?' and 'How can it be managed?' He goes on to examine in detail the key danger areas including finance, product quality, health and safety, security and the environment. With case studies, self-assessment exercises and checklists, each chapter looks systematically at what is involved and enables you to draw up action plans that could, for example, provide a defence in law or reduce your insurance premium. The new edition reflects the changes in the global environment, the new risks that have emerged and the effect of macroeconomic factors on business profitability and success. The author has also included a set of case studies to illustrate his ideas in practice.

Download or read book Risk Conscious Operations Management written by Prabhakar V. Varde and published by Springer Nature. This book was released on 2023-01-30 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents various concepts and applications related to risk-conscious operations management. It also provides an overview of the risk-based engineering – fundamental to the concept of risk-conscious operations management. It presents the reliability concept to support Dependency Modelling, which includes hardware systems structures and components for reliability improvement and risk reduction. The book further develops and builds attributes and model for risk-conscious culture – critical to characterize operational approach to risk and presents human factor modelling, where it works on developing an approach for human error precursor analysis. This book will be useful for students, researchers, academicians and professionals working on identifying risk and reliability issues in complex safety and mission critical systems. It will also be beneficial for industry risk-and-reliability experts and operational safety staff working in the complex engineering systems.

Download or read book PROCEEDINGS OF THE 2024 INTERNATIONAL CONFERENCE ON APPLIED ECONOMICS MANAGEMENT SCIENCE AND SOCIAL DEVELOPMENT AEMSS 2024 written by T. RAMAYAH; PUI MUN LEE; EDWARD H. K. NG. and published by Springer Nature. This book was released on 2024 with total page 681 pages. Available in PDF, EPUB and Kindle. Book excerpt: