Download or read book Risk Assessment for Human Metal Exposures written by Gunnar F. Nordberg and published by Academic Press. This book was released on 2018-08-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk Assessment for Human Metal Exposures: Mode of Action and Kinetic Approaches examines the current principles of risk assessment in human metal exposures, with a focus on Mode of Action(MOA), Toxicokinetic and Toxicodynamic (TKTD) considerations, and computer models. Derived from the highly respected Handbook on the Toxicology of Metals, Fourth Edition (2014), the book summarizes principles and methods and provides examples of how MOA –TKTD can be used. In addition, it presents tactics on how information generated by such methods can be confirmed by epidemiological data. Furthermore, it demonstrates how epidemiological data can be confirmed and evaluated by the examined models and considerations. This resource uniquely integrates several important topics, such as risk assessment, characterization, management and communication—the classic risk assessment paradigm—with mode of action, TKTD, and epidemiology, all topics related to human exposure. Written by pioneers in the field, this book is an essential reference for researchers, students and technicians in toxicology and risk assessment. Covers fundamental risk assessment concerns for the effects of metals on human health Provides an easy-to-use structure to quickly locate specific methods Uses case studies to illustrate the methods and theories described Written to be understood by students, researchers and industry workers who need to conduct risk assessment in metals and human health

Download or read book Issue Paper on the Human Health Effects of Metals written by and published by . This book was released on 2004 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Risk Assessment and Risk Management of Non ferrous Metals written by George M. Gray and published by . This book was released on 1997 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Issue Paper on Metal Exposure Assessment written by and published by . This book was released on 2004 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Toxicity Mechanisms Exposure Toxicokinetic and Risk Assessment Aspects of Metals Toxic for Animals and Humans written by Yanzhu Zhu and published by Frontiers Media SA. This book was released on 2022-03-10 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Infrastructure and Systems for Risk Assessment of Metal and Metal Compounds on Human Health written by Dave K. Verma and published by . This book was released on 1996 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Chemical Risk Assessment written by Ronald Eisler and published by CRC Press. This book was released on 2000-04-12 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written over a period of 17 years, the Handbook of Chemical Risk Assessment exhaustively examines and analyzes the world literature on chemicals entering the environment from human activities. The three volumes cover chemicals recommended by environmental specialists of the U.S. Fish and Wildlife Service and other resource managers. The choices were based on the real or potential impact of each contaminant and on the knowledge available about their mitigation. The information for each chemical includes source and use; physical, chemical, and metabolic properties; concentrations in field collections of abiotic materials and living organisms; deficiency effects; lethal and sublethal effects; and proposed regulatory criteria for the protection of human health and sensitive natural resources. Each chapter selectively reviews and synthesizes the technical literature on a specific priority contaminant and its effects on the environment. Successful risk assessment relies heavily on extensive and well-documented databases. They often include too much - or too little - information about too many chemicals. Of the hundreds of thousands of chemicals discharged into the environment, only a small number have sufficient information to attempt preliminary risk assessment. Sold only as a three volume set, the Handbook of Chemical Risk Assessment provides you with the exact amount of information you need in a single resource.

Download or read book Trace Metals and Infectious Diseases written by Jerome O. Nriagu and published by MIT Press. This book was released on 2024-06-11 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experts explore the influence of trace metals on the pathogenesis of infectious diseases. Many parts of the world in which common infectious diseases are endemic also have the highest prevalence of trace metal deficiencies or rising rates of trace metal pollution. Infectious diseases can increase human susceptibility to adverse effects of metal exposure (at suboptimal or toxic levels), and metal excess or deficiency can increase the incidence or severity of infectious diseases. The co-clustering of major infectious diseases with trace metal deficiency or toxicity has created a complex web of interactions with serious but poorly understood health repercussions, yet has been largely overlooked in animal and human studies. This book focuses on the distribution, trafficking, fate, and effects of trace metals in biological systems. Its goal is to enhance our understanding of the relationships between homeostatic mechanisms of trace metals and the pathogenesis of infectious diseases. Drawing on expertise from a range of fields, the book offers a comprehensive review of current knowledge on vertebrate metal-withholding mechanisms and the strategies employed by different microbes to avoid starvation (or poisoning). Chapters summarize current, state-of-the-art techniques for investigating pathogen-metal interactions and highlight open question to guide future research. The book makes clear that improving knowledge in this area will be instrumental to the development of novel therapeutic measures against infectious diseases. Contributors M. Leigh Ackland, Vahid Fa Andisi, Angele L. Arrieta, Michael A. Bachman, J. Sabine Becker, Robert E. Black, Julia Bornhorst, Sascha Brunke, Joseph A. Caruso, Jennifer S. Cavet, Anson C. K. Chan, Christopher H. Contag, Heran Darwin, George V. Dedoussis, Rodney R. Dietert, Victor J. DiRita, Carol A. Fierke, Tamara Garcia-Barrera, David P. Giedroc, Peter-Leon Hagedoorn, James A. Imlay, Marek J. Kobylarz, Joseph Lemire, Wenwen Liu, Slade A. Loutet, Wolfgang Maret, Andreas Matusch, Trevor F. Moraes, Michael E. P. Murphy, Maribel Navarro, Jerome O. Nriagu, Ana-Maria Oros-Peusquens, Elisabeth G. Pacyna, Jozef M. Pacyna, Robert D. Perry, John M. Pettifor, Stephanie Pfaffen, Dieter Rehder, Lothar Rink, Anthony B. Schryvers, Ellen K. Silbergeld, Eric P. Skaar, Miguel C. P. Soares, Kyrre Sundseth, Dennis J. Thiele, Richard B. Thompson, Meghan M. Verstraete, Gonzalo Visbal, Fudi Wang, Mian Wang, Thomas J. Webster, Jeffrey N. Weiser, Günter Weiss, Inga Wessels, Bin Ye, Judith T. Zelikoff, Lihong Zhang

Download or read book Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2007-12-19 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new field of toxicogenomics presents a potentially powerful set of tools to better understand the health effects of exposures to toxicants in the environment. At the request of the National Institute of Environmental Health Sciences, the National Research Council assembled a committee to identify the benefits of toxicogenomics, the challenges to achieving them, and potential approaches to overcoming such challenges. The report concludes that realizing the potential of toxicogenomics to improve public health decisions will require a concerted effort to generate data, make use of existing data, and study data in new waysâ€"an effort requiring funding, interagency coordination, and data management strategies.

Download or read book Science and Judgment in Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 1994-01-01 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: The public depends on competent risk assessment from the federal government and the scientific community to grapple with the threat of pollution. When risk reports turn out to be overblownâ€"or when risks are overlookedâ€"public skepticism abounds. This comprehensive and readable book explores how the U.S. Environmental Protection Agency (EPA) can improve its risk assessment practices, with a focus on implementation of the 1990 Clean Air Act Amendments. With a wealth of detailed information, pertinent examples, and revealing analysis, the volume explores the "default option" and other basic concepts. It offers two views of EPA operations: The first examines how EPA currently assesses exposure to hazardous air pollutants, evaluates the toxicity of a substance, and characterizes the risk to the public. The second, more holistic, view explores how EPA can improve in several critical areas of risk assessment by focusing on cross-cutting themes and incorporating more scientific judgment. This comprehensive volume will be important to the EPA and other agencies, risk managers, environmental advocates, scientists, faculty, students, and concerned individuals.

Download or read book Human exposure assessment a guide to risk ranking risk reduction and research planning written by and published by DIANE Publishing. This book was released on with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Introduction to Chemical Exposure and Risk Assessment written by Wesley Brock Neely and published by . This book was released on 1994 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Chemical Exposure and Risk Assessment focuses on the principles involved in assessing the risks from chemical exposure. These principles include the perception of risk, an understanding of how numbers are handled, and how chemicals affect health. The book briefly describes the major sinks, such as water and air, where chemicals are introduced. This is followed by a discussion on how concentrations are estimated and risk assessments are made. A discussion of risk benefit analysis and a presentation of several case studies using the principles for assessing risks are also included.

Download or read book Toxicologic Assessment of the Army s Zinc Cadmium Sulfide Dispersion Tests written by National Research Council and published by National Academies Press. This book was released on 1997-05-30 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the 1950s and 1960s, the U.S. Army conducted atmospheric dispersion tests in many American cities using fluorescent particles of zinc cadmium sulfide (ZnCdS) to develop and verify meteorological models to estimate the dispersal of aerosols. Upon learning of the tests, many citizens and some public health officials in the affected cities raised concerns about the health consequences of the tests. This book assesses the public health effects of the Army's tests, including the toxicity of ZnCdS, the toxicity of surrogate cadmium compounds, the environmental fate of ZnCdS, the extent of public exposures from the dispersion tests, and the risks of such exposures.

Download or read book EPA 630 R written by and published by . This book was released on 1998 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Environmental Heavy Metal Pollution and Effects on Child Mental Development written by Lubomir I. Simeonov and published by Springer Science & Business Media. This book was released on 2010-11-19 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heavy metals can be emitted into environment by both natural and anthropogenic sources, mainly mining and industrial activity. Human exposure occurs through all environmental media. Infants are more susceptible to the adverse effects of exposure. Increasing attention is now being paid to the mental development of children exposed to heavy metals. The purpose of this book is to evaluate the existing knowledge on intellectual impairment in children exposed to heavy metals in their living environment and to identify the research needs in order to obtain a clearer picture of the situation in countries and regions at risk, in which the economy is closely related to metallurgy and heavy metals emission, and to recommend a strategy for human protection. In greater detail the main objectives could be formulated as follows: to review the principal sources of single, and complex mixtures of, heavy metal pollutants in the environment; to identify suitable methodology for chemical analyses in the environment and in humans; to evaluate the existing methods for measuring mental impairment, including their reliability and validity; to recommend a standard testing protocol to be used in future research; to assess the future role of environmental heavy metal pollution in countries and regions at risk and its effects on children’s neurological development; to recommend a prevention strategy for protecting children’s health and development.

Download or read book Practical Environmental Analysis written by Miroslav Radojevic and published by Royal Society of Chemistry. This book was released on 2015-11-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: New techniques, improved understanding and changes in regulations relating to environmental analysis means that students, technicians and lecturers alike need an up-to-date guide to practical environmental analysis. This unique book provides detailed instructions for practical experiments in environmental analysis. The comprehensive coverage includes the chemical analysis of important pollutants in air, water, soil and plant tissue, and the experiments generally require only basic laboratory equipment and instrumentation. The content is supported by theoretical material explaining, amongst other concepts, the principles behind each method and the importance of various pollutants. Also included are suggestions for projects and worked examples. Appendices cover environmental standards, practical safety and laboratory practice. Building on the foundations laid by the highly acclaimed first edition, this new edition has been revised and updated to include information on new monitoring techniques, the Air Quality Index, internet resources and professional ethics. Like its predecessor, this informative text is certain to be valued as an indispensable guide to practical environmental analysis by students on a variety of science courses and their lecturers. Reviews of the first edition: "I strongly urge academics in chemistry, biology, botany, soil science, geography and environmental science departments to give [this book] serious consideration as a course text." Malcolm Cresser, Environment Department, University of York, UK "Destined to become a course text for many university courses ... a high quality, informative introductory text ... there should be multiple copies on most university's library shelves." Environmental Conservation

Download or read book Handbook on the Toxicology of Metals written by Monica Nordberg and published by Elsevier. This book was released on 2011-04-28 with total page 1024 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of the Toxicology of Metals is the standard reference work for physicians, toxicologists and engineers in the field of environmental and occupational health. This new edition is a comprehensive review of the effects on biological systems from metallic elements and their compounds. An entirely new structure and illustrations represent the vast array of advancements made since the last edition. Special emphasis has been placed on the toxic effects in humans with chapters on the diagnosis, treatment and prevention of metal poisoning. This up-to-date reference provides easy access to a broad range of basic toxicological data and also gives a general introduction to the toxicology of metallic compounds. * Covers up-to-date toxicological information on 31 metallic elements and their compounds, each in a separate chapter * New chapters on general chemistry, biological monitoring and biomarkers, essential metals, principles for prevention of the toxic effects of metals, and more