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Download or read book Ribosome inactivating Proteins written by Fiorenzo Stirpe and published by John Wiley & Sons. This book was released on 2014-06-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain.
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