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Book The Role of Ribosomal Protein S1 in Species specific Protein Synthesis

Download or read book The Role of Ribosomal Protein S1 in Species specific Protein Synthesis written by Mark Wayne Roberts and published by . This book was released on 1987 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book RpsA and Ribosomal Protein S1

Download or read book RpsA and Ribosomal Protein S1 written by Justin R. J. Vigar and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Translation initiation rates are fine-tuned by altering interactions between the ribosome and the translation initiation region of an mRNA. In bacteria varying levels of RNA structure attenuate these interactions by masking the ribosome-binding site from the small ribosomal subunit. Recent studies have described diverse strategies for recruiting mRNA to the ribosome, and highlighted the contributions of ribosomal protein S1. Here, I provide evidence that the non-canonical initiation mechanism that governs translation of the rpsA mRNA, encoding ribosomal protein S1, contains a three-dimensional architecture that is required for efficient translation. Furthermore, S1 plays an essential role during the initiation phase of translation by recruiting mRNA to the ribosome-unfolding structured mRNAs, and allowing for correct start codon positioning on the ribosome. Combining crosslinking immunoprecipitation and high-throughput sequencing approaches revealed the extent of S1's involvement in mRNA recruitment, while also highlighting a broader role as a regulator of many RNA classes.

Book Nucleic Acid Binding Properties of E  Coli Ribosomal Protein S1

Download or read book Nucleic Acid Binding Properties of E Coli Ribosomal Protein S1 written by David Ernest Draper and published by . This book was released on 1977 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Identification of Optimal Overexpression and Purification Condition for Ribosomal Protein S1 from Escherichia Coli

Download or read book Identification of Optimal Overexpression and Purification Condition for Ribosomal Protein S1 from Escherichia Coli written by Yatna Pratik Patel and published by . This book was released on 2016 with total page 22 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book The RpsA Gene and Its Product Ribosomal Protein S1

Download or read book The RpsA Gene and Its Product Ribosomal Protein S1 written by Jalyce L. Heller and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The rpsA gene contains a translation initiation region (TIR) which lacks a Shine-Dalgarno element, is highly structured, and which efficiently drives translation in bacteria. The rpsA gene is downregulated by its gene product, ribosomal protein S1. To investigate how the structure of the TIR facilitates function both in translation and downregulation, we employed a combined SAXS, SHAPE, and computational approach. The structure-function relationship reveals that the introduction of single nucleotide substitutions in the TIR alters its structure, corresponding to a modulated translation efficiency in vivo. The activity of the rpsA TIR in a minimal in vitro transcription/translation system was investigated to understand the TIR's requirement for additional factors. We observed that S1 is strictly required for its translation, and that S1 specifically recognizes and binds to the TIR when in excess over ribosomes. The structure-driven mechanism of this TIR may represent a previously overlooked strategy of translation initiation in bacteria.

Book RNA protein Interactions

Download or read book RNA protein Interactions written by Kiyoshi Nagai and published by Oxford University Press, USA. This book was released on 1994 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of RNA-protein interactions is crucial to understanding the mechanisms and control of gene expression and protein synthesis. The realization that RNAs are often far more biologically active than was previously appreciated has stimulated a great deal of new research in this field. Uniquely, in this book, the world's leading researchers have collaborated to produce a comprehensive and current review of RNA-protein interactions for all scientists working in this area. Timely, comprehensive, and authoritative, this new Frontiers title will be invaluable for all researchers in molecular biology, biochemistry and structural biology.

Book Ribosomal Protein S1

    Book Details:
  • Author : Jesper Cairo Westergaard
  • Publisher :
  • Release : 2006
  • ISBN :
  • Pages : 33 pages

Download or read book Ribosomal Protein S1 written by Jesper Cairo Westergaard and published by . This book was released on 2006 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Cell Free Translation Systems

Download or read book Cell Free Translation Systems written by A.S. Spirin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a unique book that describes the most recent achievements in the methodology of protein biosynthesis under cell-free conditions. Various versions of cell-free protein-synthesizing systems and their applications to production of individual proteins on a preparative scale are reviewed. The most recent, advanced methodologies, such as continuous-exchange and continuous-flow cell-free systems and novel effecting batch-format cell-free procedures, are considered. Special attention is drawn to the possibilities of structural (NMR; X-ray) analysis of various gene expression products with the use of a new generation of cell-free systems.

Book Studies on the Translation of Gengenetic Message

Download or read book Studies on the Translation of Gengenetic Message written by Joseph Sobura and published by . This book was released on 1975 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Xenopus Laevis Ribosomal Protein S1

Download or read book Xenopus Laevis Ribosomal Protein S1 written by Cleve Ray-Dean Sinor and published by . This book was released on 1994 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Protein Synthesis and Ribosome Structure

Download or read book Protein Synthesis and Ribosome Structure written by Knud H. Nierhaus and published by John Wiley & Sons. This book was released on 2009-07-10 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knud Nierhaus, who has studied the ribosome for more than 30 years, has assembled here the combined efforts of several scientific disciplines into a uniform picture of the largest enzyme complex found in living cells, finally resolving many decades-old questions in molecular biology. In so doing he considers virtually all aspects of ribosome structure and function -- from the molecular mechanism of different ribosomal ribozyme activities to their selective inhibition by antibiotics, from assembly of the core particle to the regulation of ribosome component synthesis. The result is a premier resource for anyone with an interest in ribosomal protein synthesis, whether in the context of molecular biology, biotechnology, pharmacology or molecular medicine.

Book Non Natural Amino Acids

Download or read book Non Natural Amino Acids written by and published by Academic Press. This book was released on 2009-07-24 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: By combining the tools of organic chemistry with those of physical biochemistry and cell biology, Non-Natural Amino Acids aims to provide fundamental insights into how proteins work within the context of complex biological systems of biomedical interest. The critically acclaimed laboratory standard for 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. With more than 400 volumes published, each Methods in Enzymology volume presents material that is relevant in today's labs -- truly an essential publication for researchers in all fields of life sciences. - Demonstrates how the tools and principles of chemistry combined with the molecules and processes of living cells can be combined to create molecules with new properties and functions found neither in nature nor in the test tube - Presents new insights into the molecular mechanisms of complex biological and chemical systems that can be gained by studying the structure and function of non-natural molecules - Provides a "one-stop shop" for tried and tested essential techniques, eliminating the need to wade through untested or unreliable methods

Book The Molecular Biology of Plastids

Download or read book The Molecular Biology of Plastids written by Indra Vasil and published by Academic Press. This book was released on 2012-12-02 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Molecular Biology of Plastids: Cell Culture and Somatic Cell Genetics of Plants, Volume 7A deals with various aspects of plastid nucleic acid and protein metabolism. This book is organized into 10 chapters. Chapter 1 provides the introduction to the molecular biology of plastids, followed by a discussion of the maps of restriction endonuclease sites on chloroplast chromosomes in Chapter 2. Chapter 3 focuses on chloroplast gene transmission, while Chapters 4 to 7 describe the apparatus for nucleic acid and protein metabolism and how some transcripts of chloroplast genes are processed. The ribosomal proteins, ribosomes, and translation in plastids are covered in Chapter 8. The last two chapters consider the organization, operation, and transport of polypeptides through the outer plastid membranes. This volume is a good reference for plant molecular biologist, genetic engineers, and researchers conducting work on the molecular biology of chloroplasts.

Book The Eukaryotic Ribosome

    Book Details:
  • Author : Heinz Bielka
  • Publisher : Walter de Gruyter GmbH & Co KG
  • Release : 1982-12-31
  • ISBN : 3112729757
  • Pages : 340 pages

Download or read book The Eukaryotic Ribosome written by Heinz Bielka and published by Walter de Gruyter GmbH & Co KG. This book was released on 1982-12-31 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "The Eukaryotic Ribosome".