Download or read book Principles of Biochemical Toxicology Third Edition written by John Timbrell and published by CRC Press. This book was released on 1999-10-21 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research into the biochemical basis of toxicology has expanded rapidly over recent years, amidst concerns over the adverse effects of drugs, environmental pollution and occupational hazards. Following on from the acclaimed first two editions of Principles of Biochemical Toxicology, John Timbrell has expanded the text to include: summary sections questions and model answers thoroughly revised artwork These features, plus the new easy-to-read format will make biochemical toxicology more accessible to undergraduates and postgraduates coming across the subject for the first time, particularly when undertaking self-directed study. This comprehensive textbook provides a thorough explanation of dose-response relationships; disposition and metabolism; toxic responses to foreign compounds, and detailed examples to illustrate mechanisms of toxicity. There is also an expanded and updated bibliography, directing the reader to further reading if required. Students and lecturers will find the clear and concise approach, which established this book as the leading textbook in its field, an essential aid to learning and teaching.
Download or read book Molecular and Biochemical Toxicology written by Robert C. Smart and published by John Wiley & Sons. This book was released on 2017-11-06 with total page 1234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written as an advanced text for toxicology students, this book is much more than an introduction and provides in-depth information describing the underlying mechanisms through which toxicants produce their adverse responses. • Links traditional toxicology to modern molecular techniques, important for teaching to graduate courses and professional studies • Uses a didactic approach with basic biological or theoretical background for the methodology presented • Brings together and comprehensively covers a range of dynamic aspects in biochemical and molecular toxicology • Guides student and professional toxicologists in comprehending a broad range of issues, compiled and authored by a diverse group of experts • “A good introductory textbook covering the biochemical toxicology of organic substances and the relevant methodology in some detail.... It offers good value for money and can be recommended as a textbook for appropriate courses” – BTS Newsletter review of the 4th edition
Download or read book Introduction to Biochemical Toxicology written by Ernest Hodgson and published by Wiley-Interscience. This book was released on 2001-02-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Biochemical Toxicology Third Edition Over the past several decades, biochemical toxicology has contributed greatly to the advancement of scientific disciplines ranging from medicine and pharmacology to environmental science and industrial hygiene. In its never-ending quest to define the biochemical, cellular, and molecular events occurring when toxicants interact with organisms, biochemical toxicology provides the rational basis for, among other things, our understanding of acute and chronic toxic processes, the development of new therapies, the determination of toxic hazards, and the development of medical and agricultural biocides. Recent applications of new molecular and cellular techniques have greatly expanded our knowledge of how toxicants produce their adverse effects. As a consequence, the time has come for a substantial revision of Professor Ernest Hodgson's classic reference in the field. This Third Edition now contains updated overview chapters on immunochemical and molecular techniques. It also features entirely new chapters covering such crucial topics as immunotoxicology, cutaneous toxicology, reproductive and developmental toxicology, and molecular epidemiology.
Download or read book Molecular Toxicology written by P. David Josephy and published by . This book was released on 2006 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: The science of toxicology has progressed considerably since Molecular Toxicology was first published in 1997. New advances in biochemical and molecular biological experimental techniques have helped researchers understand the precise effects of toxins and foreign compounds on living things atthe molecular, cellular, and organismal levels. Breakthrough research has recently been completed illuminating the human genome and the role of enzymes in toxic biochemical reaction mechanisms. Toxicology now covers drug metabolism and design, carcinogenesis, programmed cell death, and DNA repair,among other subjects. The second edition captures these and other advances, and broadens its scope to address the experimental science of toxicology. The first edition of Molecular Toxicology has become an indispensable resource for graduate students in molecular and biochemical toxicology courses,as well as academic researchers and industrial researchers in toxicology. Rigorously updated and revised, the new edition commands an unrivaled authority in the field of molecular toxicology.
Download or read book Toxicological Evaluation of Chemical Interactions written by and published by . This book was released on 1994 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Scientific Directory and Annual Bibliography written by National Institutes of Health (U.S.) and published by . This book was released on 1986 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Controlled Release Biochemical Effects of Pesticides Inhibition of Plant Pathogenic Fungi written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the middle of the Sixties, new types of formulation for biologically active com pounds have been developed, which have been introduced into the literature under the term Controlled Release Formulations (CRF). Stimulated by results from former and successful pharmaceutical research, which was engaged in the production of prepa rations with protracted effects (introduction onto the market in the year 1952 of D amphetamine in the form of pellets, coated to varying degrees with fats and waxes) 1), experiments were carried out to transfer the prolongation of effectiveness to pesticidal substances also, by means of a depot formulation. Initial work was concerned with the production of protective coatings for sonar systems in marine ecosystems. By means of antifouling paints or rubber coatings containing tri-n-butyl-tin oxide (TBTO), the growth of marine organisms on sonar domes, buoys and hulls in the water could be effectively prevented 2. 3). Controlled release formUlations of pesticides are defined as depot systems which continuously release their toxic constituents into the environment over a specified period of time (usually months to years) 4). According to this definition, such formu lations can be successfully employed where a chronic exposure to biologically active compounds is required over a longer period. The following hypothetical example is intended to illustrate this 5). In Fig. 1, the duration of activity of a non-persistent pesticide with a loss rate under environmental conditions of t1/2 = 15 days, is graphically illustrated.
Download or read book Mechanistic Toxicology written by Urs A. Boelsterli and published by CRC Press. This book was released on 2007-03-23 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology. Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity. New in the Second Edition Updated chapters Types of toxic responses Disruption of signal transduction by xenobiotics Disruption of mitochondrial function Novel mechanisms derived from systems toxicology
Download or read book Books in Print written by and published by . This book was released on 1994 with total page 2132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Environmental Health Perspectives written by and published by . This book was released on 1993 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fire Retardancy of Polymeric Materials written by Arthur F. Grand and published by CRC Press. This book was released on 2000-04-05 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume addresses the state of the art in fire retardancy studies and the need for fire retardant chemicals and fire-retarded polymers, while considering the interrelationship among polymer degradation, fire retardant efficacy, fire testing and environmental concerns. The work examines the principles of polymer science with respect to fire retardancy.
Download or read book Electron Spin Resonance written by P B Ayscough and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.
Download or read book Target Organ Toxicity Volume I written by Cohen and published by CRC Press. This book was released on 2020-01-29 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.
Download or read book Fundamentals Of Aquatic Toxicology written by Gary M. Rand and published by CRC Press. This book was released on 2020-08-06 with total page 1152 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is divided into three parts. The first part describes basic toxicological concepts and methodologies used in aquatic toxicity testing, including the philosophies underlying testing strategies now required to meet and support regulatory standards. The second part of the book discusses various factors that affect transport, transformation, ultimate distribution, and accumulation of chemicals in the aquatic environment, along with the use of modelling to predict fate.; The final section of the book reviews types of effects or endpoints evaluated in field studies and the use of structure-activity relationships in aquatic toxicology to predict biological activity and physio-chemical properties of a chemical. This section also contains an extensive background of environmental legislation in the USA and within the European Community, and an introduction to hazard/risk assessment with case studies.
Download or read book Environmental Toxicology and Risk Assessment written by Wayne G. Landis and published by ASTM International. This book was released on 1993 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Reviews of Environmental Contamination and Toxicology Volume 257 written by Pim de Voogt and published by Springer Nature. This book was released on 2021-11-17 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1985 with total page 1728 pages. Available in PDF, EPUB and Kindle. Book excerpt:
