Download or read book Reverse Engineering of Regulatory Networks written by Sudip Mandal and published by Springer Nature. This book was released on 2023-11-07 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details the development of updated dry lab and wet lab based methods for the reconstruction of Gene regulatory networks (GRN). Chapters guide readers through culprit genes, in-silico drug discovery techniques, genome-wide ChIP-X data, high-Throughput Transcriptomic Data Exome Sequencing, Next-Generation Sequencing, Fuorescence Spectroscopy, data analysis in Bioinformatics, Computational Biology, and S-system based modeling of GRN. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Reverse Engineering of Regulatory Networks aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.
Download or read book LINKING THE GENES written by ALBERTO. DE LA FUENTE and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Reverse Engineering of Gene Regulatory Networks for Discovery of Novel Interactions in Pathways Using Gene Expression Data written by Tanwir Habib and published by . This book was released on 2009 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Towards Reverse Engineering Gene Regulatory Networks written by Thomas Schlitt and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Reverse Engineering Biological Networks written by Gustavo Stolovitzky and published by Wiley-Blackwell. This book was released on 2007-12-26 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This volume is the result of a workshop entitled Dialogue on Reverse Engineering Assessment and Methods (DREAM) held on September 7-8, 2006, at Wave Hill, New York"--P [vii].
Download or read book System Identification Methods for Reverse Engineering Gene Regulatory Networks written by Zhen Wang and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Gene Network Inference written by Alberto Fuente and published by Springer Science & Business Media. This book was released on 2014-01-03 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents recent methods for Systems Genetics (SG) data analysis, applying them to a suite of simulated SG benchmark datasets. Each of the chapter authors received the same datasets to evaluate the performance of their method to better understand which algorithms are most useful for obtaining reliable models from SG datasets. The knowledge gained from this benchmarking study will ultimately allow these algorithms to be used with confidence for SG studies e.g. of complex human diseases or food crop improvement. The book is primarily intended for researchers with a background in the life sciences, not for computer scientists or statisticians.
Download or read book Gene Regulatory Networks written by Guido Sanguinetti and published by Humana. This book was released on 2018-12-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores recent techniques for the computational inference of gene regulatory networks (GRNs). The chapters in this book cover topics such as methods to infer GRNs from time-varying data; the extraction of causal information from biological data; GRN inference from multiple heterogeneous data sets; non-parametric and hybrid statistical methods; the joint inference of differential networks; and mechanistic models of gene regulation dynamics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, descriptions of recently developed methods for GRN inference, applications of these methods on real and/ or simulated biological data, and step-by-step tutorials on the usage of associated software tools. Cutting-edge and thorough, Gene Regulatory Networks: Methods and Protocols is an essential tool for evaluating the current research needed to further address the common challenges faced by specialists in this field.
Download or read book Time Lagged Information Theoretic Approaches to the Reverse Engineering of Gene Regulatory Networks written by Vijender Chaitankar and published by . This book was released on 2010 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Reverse Engineering Gene Regulatory Networks written by Vincenzo Belcastro and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Combining Heterogeneous Sources of Data for the Reverse engineering of Gene Regulatory Networks written by Emma Steele and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Reverse Engineering written by A.C. Telea and published by IntechOpen. This book was released on 2012-03-07 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reverse engineering encompasses a wide spectrum of activities aimed at extracting information on the function, structure, and behavior of man-made or natural artifacts. Increases in data sources, processing power, and improved data mining and processing algorithms have opened new fields of application for reverse engineering. In this book, we present twelve applications of reverse engineering in the software engineering, shape engineering, and medical and life sciences application domains. The book can serve as a guideline to practitioners in the above fields to the state-of-the-art in reverse engineering techniques, tools, and use-cases, as well as an overview of open challenges for reverse engineering researchers.
Download or read book Reverse Engineering of RNA Regulatory Networks written by David Nellinger Adamson and published by . This book was released on 2013 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding gene regulation is of central importance to biology because controlling when, where, and how genes are expressed accounts for a large proportion of the complexity and organization of living systems. While for many years RNA was largely thought of as the middleman for converting genetic information into biochemically active proteins, it has become increasingly clear that RNAs are also major players gene regulation. This thesis examines the functional properties of regulatory RNAs in the context of bacterial RNA networks. More specifically, the three studies presented here examine signaling dynamics and crosstalk within the CsrA and Hfq-dependent small RNA regulatory systems; each of these systems (i) contain non-coding RNAs which regulate the translation of multiple target messenger RNAs, (ii) have central roles in coordinating their cells' adaptation to environmental change, and (iii) are evolutionarily conserved across a wide range of bacterial species. In this work, a combination of synthetic biology and mathematical modeling are brought to bear to uncover the operational behavior and potential of the these two model RNA networks.
Download or read book An Ensemble Learning Approach to Reverse engineering Transcriptional Regulatory Networks from Time series Gene Expression Data written by and published by . This book was released on 2009 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Analysis of Deterministic Cyclic Gene Regulatory Network Models with Delays written by Mehmet Eren Ahsen and published by Birkhäuser. This book was released on 2015-02-25 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brief examines a deterministic, ODE-based model for gene regulatory networks (GRN) that incorporates nonlinearities and time-delayed feedback. An introductory chapter provides some insights into molecular biology and GRNs. The mathematical tools necessary for studying the GRN model are then reviewed, in particular Hill functions and Schwarzian derivatives. One chapter is devoted to the analysis of GRNs under negative feedback with time delays and a special case of a homogenous GRN is considered. Asymptotic stability analysis of GRNs under positive feedback is then considered in a separate chapter, in which conditions leading to bi-stability are derived. Graduate and advanced undergraduate students and researchers in control engineering, applied mathematics, systems biology and synthetic biology will find this brief to be a clear and concise introduction to the modeling and analysis of GRNs.
Download or read book Computational Science and Its Applications ICCSA 2018 written by Osvaldo Gervasi and published by Springer. This book was released on 2018-07-03 with total page 778 pages. Available in PDF, EPUB and Kindle. Book excerpt: The five volume set LNCS 10960 until 10964 constitutes the refereed proceedings of the 18th International Conference on Computational Science and Its Applications, ICCSA 2018, held in Melbourne, Australia, in July 2018. Apart from the general tracks, ICCSA 2018 also includes 34 international workshops in various areas of computational sciences, ranging from computational science technologies, to specific areas of computational sciences, such as computer graphics and virtual reality. The total of 265 full papers and 10 short papers presented in the 5-volume proceedings set of ICCSA 2018, were carefully reviewed and selected from 892 submissions.
Download or read book Reverse Engineering of Gene Regulatory Networks Governing Cell cell Communication in the Microenvironment of Pancreatic Cancer written by Zbigniew Rogon-Lamparski and published by . This book was released on 2011 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt:
