Download or read book A History of the Development of Alternatives to Animals in Research and Testing written by John Parascandola and published by Purdue University Press. This book was released on 2024-07-15 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: Growing public interest in animal welfare issues in recent decades has prompted increased attention to the efforts to develop alternative, nonanimal methods for use in biomedical research and product testing. In A History of the Development of Alternatives to Animals in Research and Testing, the first book-length study of the subject, John Parascandola traces the history of the concept of alternatives to the use of animals in research and testing in Britain and the United States from its beginnings until it had become firmly established in the scientific and animal protection communities by the end of the 1980s. This account of the history of alternatives is set within the context of developments within science, animal welfare, and politics. The book covers the key role played by animal welfare advocates in promoting alternatives, the initial resistance to alternatives on the part of many in the scientific community, the opportunity provided by alternatives for compromise and cooperation between these two groups, and the dominance of the “Three Rs”—reduction, refinement, and replacement.

Download or read book Rethinking the American Animal Rights Movement written by Emily Patterson-Kane and published by Routledge. This book was released on 2022-02-25 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Along with Civil Rights and Women’s liberation, Animal Rights became one of leading social moments of the twentieth century. This book critically reviews all principal contributions to the American animal rights debate by activists, campaigners, academics, and lawyers, while placing animal rights in context with other related and competing movements. Rethinking the American Animal Rights Movement examines the strategies employed within the movement to advance its goals, which ranged from public advocacy and legal reforms to civil disobedience, vigilantism, anarchism, and even "terrorism." It summarizes key theoretical and legal frameworks that inspired those strategies, as well as the ideological motivations of the movement. It highlights the irreconcilable tension between moral and legal rights verses "humane treatment of animals" as prescribed by advocates of animal welfarism. The book also looks back to the nineteenth century origins of the movement, examining its appeal to a sentimentalist conception of rights standing in marked contrast with twentieth century rights theory. After providing an extensive social history of the twentieth century movement, the book subsequently offers a diagnosis of why it stalled at the turn of millennium in its various efforts to advance the cause of nonhuman animals. This diagnosis emphasizes the often-contradictory goals and strategies adopted by the movement in its different phases and manifestations across three centuries. The book is unique in presenting students, activists, and scholars with a history and critical discussion of its accomplishments, failures, and ongoing complexities faced by the American animal rights movement.

Download or read book Towards a New 3Rs Era in Experimental Research written by Christopher R. Cederroth and published by Frontiers Media SA. This book was released on 2024-04-29 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the persisting need of animal experimentation for fundamental and applied research, the relevance and importance of the 3Rs Principle cannot be ignored. The 3Rs Principle was put forward over 50 years ago, providing an essential framework for more humane animal experimentation in research. In this half-century the research landscape within which this principle is applied has dramatically changed and evolved, with ever more emerging venues to explore for 3Rs advancement and implementation.

Download or read book Animal Experimentation written by Kathrin Herrmann and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Experimentation: Working Towards a Paradigm Change critically appraises current animal use in science and discusses ways in which we can contribute to a paradigm change towards human-biology based approaches.

Download or read book Principles of Research Methodology and Ethics in Pharmaceutical Sciences written by Vikas Anand Saharan and published by CRC Press. This book was released on 2024-08-30 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical researchers are constantly looking for drug products, drug delivery systems and devices for improving the health of society. A scientific and systematic search for new knowledge requires a thorough understanding of research methods and hypothesis design. This volume presents pharmaceutical research through theoretical concepts, methodologies and ethical issues. It fulfils publication ethics course work requirements for students. Chapters have been designed to cater for the curriculum requirements of universities globally. This serves as a guide on how to apply concepts in designing experiments and transforming laboratory research into actual practice. Features: · Complete coverage of research methodology courses for graduate and postgraduate students globally. · Step-by-step assistance in writing technical reports, projects, protocols, theses and dissertations. · Experimental designing in pharmaceutical formulation development and preclinical research designs. · Ethics in using animals in preclinical research and humans in clinical research. · Publication ethics, best practices and guidelines for ensuring ethical writing. · Hypothetical and real-world case studies on ethical issues and measures for prevention and control.

Download or read book The Ethics of Animal Research written by Jeremy R. Garrett and published by MIT Press. This book was released on 2012-03-30 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: A balanced, accessible discussion of whether and on what grounds animal research can be ethically justified. An estimated 100 million nonhuman vertebrates worldwide—including primates, dogs, cats, rabbits, hamsters, birds, rats, and mice—are bred, captured, or otherwise acquired every year for research purposes. Much of this research is seriously detrimental to the welfare of these animals, causing pain, distress, injury, or death. This book explores the ethical controversies that have arisen over animal research, examining closely the complex scientific, philosophical, moral, and legal issues involved. Defenders of animal research face a twofold challenge: they must make a compelling case for the unique benefits offered by animal research; and they must provide a rationale for why these benefits justify treating animal subjects in ways that would be unacceptable for human subjects. This challenge is at the heart of the book. Some contributors argue that it can be met fairly easily; others argue that it can never be met; still others argue that it can sometimes be met, although not necessarily easily. Their essays consider how moral theory can be brought to bear on the practical ethical questions raised by animal research, examine the new challenges raised by the emerging possibilities of biotechnology, and consider how to achieve a more productive dialogue on this polarizing subject. The book's careful blending of theoretical and practical considerations and its balanced arguments make it valuable for instructors as well as for scholars and practitioners.

Download or read book Reducing Refining and Replacing the Use of Animals in Toxicity Testing written by Dave Allen and published by Royal Society of Chemistry. This book was released on 2013-10-31 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicity testing is used to assess the safety or hazards presented by substances such as industrial chemicals, consumer products, and pharmaceuticals. At present, many methods involve laboratory animals. Alternative procedures, some involving human cell-based technologies, are now being developed which reduce, refine, or replace animal usage and minimize the pain and distress caused. These new tests must protect public health and the environment at least as well as currently accepted methods. This book describes the ever-expanding "toolbox" of methods available to assess toxicity. Such techniques often result from our growing understanding of the biochemical and cellular pathways that mediate toxicity mechanisms. This permits evaluations of information generated from several sources to generate a "weight of evidence". By combining in silico, in vitro, and ex vivo methods with technologies that rely on biochemical- and cell-based in vitro assays, toxicologists are developing mechanistically based alternatives to live animal experimentation. This text also explores the complexities associated with adequate validation, and the assessment of test reliability and relevance. It provides an essential reference source for postgraduates, academics and industrialists working in this rapidly changing area.

Download or read book Applied Ethics in Animal Research written by John P. Gluck and published by Purdue University Press. This book was released on 2002 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a collection of chapters all contributed by individuals who have presented their ideas at conferences and who take moderate stands with the use of animals in research. Specifically the chapters bear of the issues of: notions of the moral standings of animals, history of the methods of argumentation, knowledge of the animal mind, nature and value of regulatory structures, how respect for animals can be converted from theory to action in the laboratory. The chapters have been tempered by open discussion with individuals with different opinions and not audiences of true believers. It is the hope of all, that careful consideration of the positions in these chapters will leave reader with a deepened understanding--not necessarily a hardened position.

Download or read book The Design of Animal Experiments written by Michael Festing and published by SAGE Publications Limited. This book was released on 2016-12-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Where there is no alternative to the use of animals in biomedical research, it is important that experiments are well designed and correctly analysed in order to minimise pain and maximize the chance of getting scientifically valid results. Experiments that use too few animals may fail to pick up biologically important effects, while those who use them incorrectly or wastefully may get invalid results while subjecting the animals to unnecessary pain, distress or lasting harm. The Design of Animal Experiments is intended for all research scientists who use laboratory animals, with the aim of helping them to design their own experiments more effectively and/or to improve their ability to communicate with professional statisticians when necessary. It covers all randomised controlled experimental designs likely to be needed in laboratory animal research, with worked examples showing how they can be statistically analysed. It suggests the more widespread use of randomised block designs and shows how both males and females can be included in an experiment without the need to increase the total number of animals by using factorial designs. It also includes guidance on the choice of experimental animals. The book covers the learning outcomes of Module 10 and part (ii) of Module 11 of education and training under Directive 2010/63/EU.

Download or read book Handbook of Bioethical Decisions Volume I written by Erick Valdés and published by Springer Nature. This book was released on 2023-06-14 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Bioethical Decisions is aimed at addressing and analyzing the most important ethical concerns and moral quandaries arisen in biomedical and scientific research. As such, it identifies and problematizes on a comprehensive range of ethical issues researchers must deal with in different critical contexts. Thus, the Handbook, Vol. I, may be helpful for them to make decisions and deliberate in complex practical scenarios. In this fashion, the volume reunites different points of view to give readers room enough to get a better knowledge and take their own position on pressing bioethical issues of the day. Consequently, this work seeks to engender dense ethical epistemology scientists can count on when conducting latest generation biomedical research. By bringing together an impressive array of contributions on the most important elements and categories for “at the bench” bioethical decisions as well as offering chapters by some of the most world renowned and prominent experts in bioethics, the Handbook, Vol. I, is a paradigmatic text in its area and a valuable resource for courses on bioethics, and biomedical research, as well as courses that discuss ethics and the biosciences at different professional levels, biomedical industry, pharmacological companies and the public sphere in general.

Download or read book Ethics in Veterinary Practice written by Barry Kipperman and published by John Wiley & Sons. This book was released on 2022-08-23 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ethics IN Veterinary Practice An incisive examination of relevant and contemporary ethical issues facing veterinary practitioners, students, instructors, and animal researchers In Ethics in Veterinary Practice: Balancing Conflicting Interests, a team of distinguished scholars delivers a foundational exploration of animal ethics and a guide to examining contemporary issues and dilemmas that arise regularly in veterinary practice. The book offers comprehensive, quickly accessible, and up-to-date information on veterinary ethics with content devoted to unique issues by practice type. The authors offer a primary resource for veterinary ethics useful for veterinarians, faculty, instructors, senior undergraduates, and veterinary students that focuses on recognizing and addressing real-life ethical dilemmas and relevant philosophical discussions about the moral status of animals, animal rights, and interests. Ethics in Veterinary Practice presents material on integrative medicine, animal pain, moral stress, and the future of veterinary ethics. Readers will also find: A thorough introduction to a theoretical basis for veterinary ethics, including discussions of animal welfare, ethical theories, and legal issues Comprehensive explorations of clinical veterinary ethics, including discussions of veterinary advocacy, ethical dilemmas, professionalism, economic issues, and medical errors Practical discussions of ethical concerns by practice type, including companion animals, equines, and animals used for food In-depth examination of emerging ethical concerns including animal use in veterinary education and animal maltreatment Perfect for practicing veterinarians, veterinary students, and veterinary technicians and nurses, Ethics in Veterinary Practice: Balancing Conflicting Interests will also earn a place in the libraries of instructors teaching veterinary ethics, as well as biomedical and animal ethicists. “As veterinary medicine becomes more technologically and socially complex, interest in ethics is growing. Ethics in Veterinary Practice provides a needed reference from the North American perspective, for anyone facing ethical dilemmas (i.e., all of us). Suitable for practitioners, students, and technicians, the book supplies factual background and practical guidance for navigation accompanied by a clear ethical analysis of common dilemmas in all aspects of veterinary medicine.” Lisa Moses Veterinary Specialist in Internal Medicine Center for Bioethics Harvard Medical School, USA “Ethics in Veterinary Practice is a statement of both the influence of Bernie Rollin’s lifetime work and of the coming of age of veterinary ethics. From the moral status of animals to veterinary ethical dilemmas, from medical errors to professionalism, from economic issues to end-of-life decision making, Ethics in Veterinary Practice leaves no stone unturned. A must-read for students and professionals alike.” Manuel Magalhães Sant'Ana European Veterinary Specialist in Animal Welfare Science, Ethics and Law University of Lisbon, Portugal “This book makes a valuable contribution to the subject, hosting writing from a number of prominent scholars in the field. The book bravely tackles several contemporary issues including veterinary corporations, moral stress and medical errors as well as providing updated insights into the history of the profession and veterinary professionalism. Throughout, the complex and contested place of animals within our society is openly and thoughtfully explored from a veterinary perspective. “ Vanessa Ashall European Veterinary Specialist in Animal Welfare Science, Ethics and Law University of York, UK

Download or read book Alternatives to Animal Use in Research Testing and Education written by and published by . This book was released on 1986 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Statistical Rethinking written by Richard McElreath and published by CRC Press. This book was released on 2018-01-03 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Rethinking: A Bayesian Course with Examples in R and Stan builds readers’ knowledge of and confidence in statistical modeling. Reflecting the need for even minor programming in today’s model-based statistics, the book pushes readers to perform step-by-step calculations that are usually automated. This unique computational approach ensures that readers understand enough of the details to make reasonable choices and interpretations in their own modeling work. The text presents generalized linear multilevel models from a Bayesian perspective, relying on a simple logical interpretation of Bayesian probability and maximum entropy. It covers from the basics of regression to multilevel models. The author also discusses measurement error, missing data, and Gaussian process models for spatial and network autocorrelation. By using complete R code examples throughout, this book provides a practical foundation for performing statistical inference. Designed for both PhD students and seasoned professionals in the natural and social sciences, it prepares them for more advanced or specialized statistical modeling. Web Resource The book is accompanied by an R package (rethinking) that is available on the author’s website and GitHub. The two core functions (map and map2stan) of this package allow a variety of statistical models to be constructed from standard model formulas.

Download or read book Nonhuman Primate Welfare written by Lauren M. Robinson and published by Springer Nature. This book was released on 2023-02-01 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume reviews the broad topic of welfare in nonhuman primates under human care. Chapters detail the history of primates in captivity, ethical and legal issues surrounding the use of nonhuman primates as entertainment or in research, the different approaches that welfare are measured, and how housing, enrichment, and other conditions can foster or degrade welfare. Since humans began keeping nonhuman primates we have made vast strides in understanding their cognitive abilities, strong social bonds, vibrant personalities, and their capacity for joy and suffering. With an increasing number of countries banning the use of great apes in biomedical research, the welfare of primates in zoos and research facilities has gained increasing attention. This interdisciplinary work features contributors from many of the fields involved and those on both sides of the issue, thus providing an exhaustive overview of primate welfare. Readers from animal welfare science, primatology, animal testing, veterinary medicine, conservation to ethics and legislation will find this an important account.

Download or read book The Animal Research War written by P. Conn and published by Springer. This book was released on 2008-05-12 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thoughtful and surprising book analyzes the effect of animal extremism on the world's scientists, their institutions, and professional societies. The Animal Research War traces the evolution of the animal rights movement, profiles its leadership, and reveals the truth behind university animal research.

Download or read book Encyclopedia of Animal Rights and Animal Welfare 2 volumes written by Marc Bekoff and published by Bloomsbury Publishing USA. This book was released on 2009-11-25 with total page 748 pages. Available in PDF, EPUB and Kindle. Book excerpt: A landmark publishing achievement on the subject, the new edition of this acclaimed encyclopedia is expanded to two volumes, covering the full range of issues related to animal protection. Expanded to two volumes, the comprehensively updated new edition, Encyclopedia of Animal Rights and Animal Welfare: Second Edition is an extraordinary publishing event. It remains the only reference to cover the entire scope of animal rights and welfare from a global interdisciplinary perspective, with an international team of contributors assembled by Marc Bekoff covering animal treatment issues in the United States, China, India, Kenya, Australia, and many other nations. With a focused emphasis on fairness and justice for animals evident on every page, Encyclopedia of Animal Rights and Animal Welfare: Second Edition offers clear explanations of hot-button topics like puppy mills, endangered species in zoos, no-kill shelters, dog fighting, factory farming and disease, veganism, conservation ethics, wildlife contraception, and more. The encyclopedia also explores a range of religious, ethical, and philosophical views on using animals, as well as the latest research on animal cognition and sentience. The work helps readers understand the different viewpoints of animal welfare advocates who want to improve conditions for animals and animal rights activists who don't want animals used at all.

Download or read book Rethinking Food and Agriculture written by Amir Kassam and published by Woodhead Publishing. This book was released on 2020-10-18 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given the central role of the food and agriculture system in driving so many of the connected ecological, social and economic threats and challenges we currently face, Rethinking Food and Agriculture reviews, reassesses and reimagines the current food and agriculture system and the narrow paradigm in which it operates. Rethinking Food and Agriculture explores and uncovers some of the key historical, ethical, economic, social, cultural, political, and structural drivers and root causes of unsustainability, degradation of the agricultural environment, destruction of nature, short-comings in science and knowledge systems, inequality, hunger and food insecurity, and disharmony. It reviews efforts towards 'sustainable development', and reassesses whether these efforts have been implemented with adequate responsibility, acceptable societal and environmental costs and optimal engagement to secure sustainability, equity and justice. The book highlights the many ways that farmers and their communities, civil society groups, social movements, development experts, scientists and others have been raising awareness of these issues, implementing solutions and forging 'new ways forward', for example towards paradigms of agriculture, natural resource management and human nutrition which are more sustainable and just. Rethinking Food and Agriculture proposes ways to move beyond the current limited view of agro-ecological sustainability towards overall sustainability of the food and agriculture system based on the principle of 'inclusive responsibility'. Inclusive responsibility encourages ecosystem sustainability based on agro-ecological and planetary limits to sustainable resource use for production and livelihoods. Inclusive responsibility also places importance on quality of life, pluralism, equity and justice for all and emphasises the health, well-being, sovereignty, dignity and rights of producers, consumers and other stakeholders, as well as of nonhuman animals and the natural world. - Explores some of the key drivers and root causes of unsustainability , degradation of the agricultural environment and destruction of nature - Highlights the many ways that different stakeholders have been forging 'new ways forward' towards alternative paradigms of agriculture, human nutrition and political economy, which are more sustainable and just - Proposes ways to move beyong the current unsustainable exploitation of natural resources towards agroecological sustainability and overall sustainability of the food and agriculture system based on 'inclusive responsibility'