Download or read book Resistance of Pseudomonas Aeruginosa written by Michael Robert Withington Brown and published by John Wiley & Sons. This book was released on 1975 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Guidelines on Core Components of Infection Prevention and Control Programmes at the National and Acute Health Care Facility Level written by World Health Organization and published by . This book was released on 2017-01-31 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: Health care-associated infections (HAI) are one of the most common adverse events in care delivery and a major public health problem with an impact on morbidity, mortality and quality of life. At any one time, up to 7% of patients in developed and 10% in developing countries will acquire at least one HAI. These infections also present a significant economic burden at the societal level. However, a large percentage are preventable through effective infection prevention and control (IPC) measures. These new guidelines on the core components of IPC programmes at the national and facility level will enhance the capacity of Member States to develop and implement effective technical and behaviour modifying interventions. They form a key part of WHO strategies to prevent current and future threats from infectious diseases such as Ebola, strengthen health service resilience, help combat antimicrobial resistance (AMR) and improve the overall quality of health care delivery. They are also intended to support countries in the development of their own national protocols for IPC and AMR action plans and to support health care facilities as they develop or strengthen their own approaches to IPC. These are the first international evidence-based guidelines on the core components of IPC programmes. These new WHO guidelines are applicable for any country and suitable to local adaptations, and take account of the strength of available scientific evidence, the cost and resource implications, and patient values and preferences.
Download or read book Antimicrobial Drug Resistance written by Douglas Mayers and published by Springer Science & Business Media. This book was released on 2009-07-14 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: This ? rst edition of Antimicrobial Drug Resistance grew out of a desire by the editors and authors to have a comprehensive resource of information on antimicrobial drug resistance that encompassed the current information available for bacteria, fungi, protozoa and viruses. We believe that this information will be of value to clinicians, epidemiologists, microbiologists, virologists, parasitologists, public health authorities, medical students and fellows in training. We have endeavored to provide this information in a style which would be accessible to the broad community of persons who are concerned with the impact of drug resistance in our cl- ics and across the broader global communities. Antimicrobial Drug Resistance is divided into Volume 1 which has sections covering a general overview of drug resistance and mechanisms of drug resistance ? rst for classes of drugs and then by individual microbial agents including bacteria, fungi, protozoa and viruses. Volume 2 addresses clinical, epidemiologic and public health aspects of drug resistance along with an overview of the conduct and interpretation of speci? c drug resistance assays. Together, these two volumes offer a comprehensive source of information on drug resistance issues by the experts in each topic.
Download or read book Pseudomonas aeruginosa as an Opportunistic Pathogen written by Mario Campa and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assembling the latest research by an international group of contributors, this volume covers the epidemiology, pathogenesis, clinical features, and control measures of this elusive microorganism. It will provide a deeper understanding of the pathogen to physicians and surgeons caring for patients infected, or at risk of becoming infected, with Pseudomonas Aeruginosa.
Download or read book Efflux Mediated Antimicrobial Resistance in Bacteria written by Xian-Zhi Li and published by Springer. This book was released on 2016-11-09 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, written by leading international experts, provides a comprehensive, current examination of transport-mediated antimicrobial resistance. As a particularly powerful mechanism of multidrug resistance, an in-depth examination of efflux pumps is conducted with bacteria of major public health concern including Enterobacteriaceae, Acinetobacter, Neisseria, Pseudomonas, staphylococci, and mycobacteria. The content spans structural biochemistry and transport mechanisms of the major transporter families and considers individual drug efflux systems across various Gram-positive and Gram-negative species. Genomic analysis of efflux pump distribution and their contribution to clinically-relevant resistance are a major focus of the text. Moreover, interplay between drug efflux pumps and other key resistance mechanisms such as intrinsic drug impermeability, inactivation, and target alterations are discussed, as well as their molecular expression-based regulation and physiological functions beyond resistance, involving biofilms, stress response, and pathogenicity. Finally, strategies are addressed to target this drug resistance mechanism with novel antimicrobials or drug inhibitor adjuvants.
Download or read book Improving Food Safety Through a One Health Approach written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-10 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Globalization of the food supply has created conditions favorable for the emergence, reemergence, and spread of food-borne pathogens-compounding the challenge of anticipating, detecting, and effectively responding to food-borne threats to health. In the United States, food-borne agents affect 1 out of 6 individuals and cause approximately 48 million illnesses, 128,000 hospitalizations, and 3,000 deaths each year. This figure likely represents just the tip of the iceberg, because it fails to account for the broad array of food-borne illnesses or for their wide-ranging repercussions for consumers, government, and the food industry-both domestically and internationally. A One Health approach to food safety may hold the promise of harnessing and integrating the expertise and resources from across the spectrum of multiple health domains including the human and veterinary medical and plant pathology communities with those of the wildlife and aquatic health and ecology communities. The IOM's Forum on Microbial Threats hosted a public workshop on December 13 and 14, 2011 that examined issues critical to the protection of the nation's food supply. The workshop explored existing knowledge and unanswered questions on the nature and extent of food-borne threats to health. Participants discussed the globalization of the U.S. food supply and the burden of illness associated with foodborne threats to health; considered the spectrum of food-borne threats as well as illustrative case studies; reviewed existing research, policies, and practices to prevent and mitigate foodborne threats; and, identified opportunities to reduce future threats to the nation's food supply through the use of a "One Health" approach to food safety. Improving Food Safety Through a One Health Approach: Workshop Summary covers the events of the workshop and explains the recommendations for future related workshops.
Download or read book Model Organisms for Microbial Pathogenesis Biofilm Formation and Antimicrobial Drug Discovery written by Busi Siddhardha and published by Springer Nature. This book was released on 2020-03-28 with total page 685 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides essential insights into microbial pathogenesis, host-pathogen interactions, and the anti-microbial drug resistance of various human pathogens on the basis of various model organisms. The initial sections of the book introduce readers to the mechanisms of microbial pathogenesis, host-pathogen interactions, anti-microbial drug resistance, and the dynamics of biofilm formation. Due to the emergence of various microbial resistant strains, it is especially important to understand the prognosis for microbial infections, disease progression profiles, and mechanisms of resistance to antibiotic therapy in order to develop novel therapeutic strategies. In turn, the second part of the book presents a comparative analysis of various animal models to help readers understand microbial pathogenesis, host-pathogen interactions, anti-microbial drug discovery, anti-biofilm therapeutics, and treatment regimes. Given its scope, the book represents a valuable asset for microbiologists, biotechnologists, medical professionals, drug development researchers, and pharmacologists alike.
Download or read book Pseudomonas aeruginosa the Superbug written by Silpi Basak and published by Cambridge Scholars Publishing. This book was released on 2022-07-12 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pseudomonas aeruginosa is one of the most commonly isolated bacterial species in clinical microbiology laboratories and it causes infections in hospitalized patients with strains resistant to many antimicrobials. In addition, it can form a biofilm especially in cystic fibrosis patients and patients with medical devices. Extracellular polymeric substances (EPS) or extracellular matrixes in biofilm prevent access of antimicrobial agents, disinfectants, and host-produced immune responses. Antimicrobial resistance in Pseudomonas aeruginosa is multifactorial and can be due to mutation, transfer of genes by plasmids, or transposons, among other causes. Production of β-lactamases causes resistance to β-lactam drugs including Carbapenems. Against this background of emergence of antibiotic resistance, this book studies different types of β-lactamases routinely produced by Pseudomonas aeruginosa strains in clinical microbiology laboratories. It shows that, although molecular methods like Polymerase Chain Reaction (PCR) are the gold standard for detection of different types of β-lactamases, they are very costly and require expertise.
Download or read book Pseudomonas Aeruginosa written by Dinesh Sriramulu and published by BoD – Books on Demand. This book was released on 2019-10-02 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pseudomonas aeruginosa, though unfamiliar as an aggressive invader, has gained importance in the scientific community due to its association with cystic fibrosis (CF) and its ability to construct biofilms resilient to host defense. The chronic nature of CF allows this bacterium to colonize, adapt, and evolve at its own pace, thereby causing further complications in CF patients. With its huge genetic repertoire and plasticity of the genome, P. aeruginosa has been able to alter its contents by way of deletions, insertions, inversions, and so on. Therefore scientists and researchers are eager to study this bacterium in diverse and unusual niches. Written by experts from around the world, this book describes and discusses the various mechanisms of adaptation and evolution displayed by P. aeruginosa.
Download or read book Challenges to Tackling Antimicrobial Resistance written by Michael Anderson and published by Cambridge University Press. This book was released on 2020-04-23 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: An accessible overview of the challenges in tackling AMR, and the economic and policy responses of the 'One Health' approach. It will appeal to policy-makers seeking to strengthen national and local polices tackling AMR, as well as students and academics who want an overview of the latest scientific evidence regarding effective AMR policies.
Download or read book Biofilm Infections written by Thomas Bjarnsholt and published by Springer. This book was released on 2014-10-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and treatment regimes. A still increasing interest and emphasis on the sessile bacterial lifestyle biofilms has been seen since it was realized that that less than 0.1% of the total microbial biomass lives in the planktonic mode of growth. The term was coined in 1978 by Costerton et al. who defined the term biofilm for the first time.In 1993 the American Society for Microbiology (ASM) recognised that the biofilmmode of growth was relevant to microbiology. Lately many articles have been published on the clinical implications of bacterial biofilms. Both original articles and reviews concerning the biofilm problem are available.
Download or read book The Effects on Human Health of Subtherapeutic Use of Antimicrobials in Animal Feeds written by National Research Council and published by National Academies Press. This book was released on 1980-02-01 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Understanding the Creeping Crisis written by Arjen Boin and published by Springer Nature. This book was released on 2021-05-10 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book explores a special species of trouble afflicting modern societies: creeping crises. These crises evolve over time, reveal themselves in different ways, and resist comprehensive responses despite periodic public attention. As a result, these crises continue to creep in front of our eyes. This book begins by defining the concept of a creeping crisis, showing how existing literature fails to properly define and explore this phenomenon and outlining the challenges such crises pose to practitioners. Drawing on ongoing research, this book presents a diverse set of case studies on: antimicrobial resistance, climate change-induced migration, energy extraction, big data, Covid-19, migration, foreign fighters, and cyberattacks. Each chapter explores how creeping crises come into existence, why they can develop unimpeded, and the consequences they bring in terms of damage and legitimacy loss. The book provides a proof-of-concept to help launch the systematic study of creeping crises. Our analysis helps academics understand a new species of threat and practitioners recognize and prepare for creeping crises.
Download or read book Antimicrobial Resistance in Developing Countries written by Aníbal de J. Sosa and published by Springer Science & Business Media. This book was released on 2009-10-08 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Avoiding infection has always been expensive. Some human populations escaped tropical infections by migrating into cold climates but then had to procure fuel, warm clothing, durable housing, and crops from a short growing season. Waterborne infections were averted by owning your own well or supporting a community reservoir. Everyone got vaccines in rich countries, while people in others got them later if at all. Antimicrobial agents seemed at first to be an exception. They did not need to be delivered through a cold chain and to everyone, as vaccines did. They had to be given only to infected patients and often then as relatively cheap injectables or pills off a shelf for only a few days to get astonishing cures. Antimicrobials not only were better than most other innovations but also reached more of the world’s people sooner. The problem appeared later. After each new antimicrobial became widely used, genes expressing resistance to it began to emerge and spread through bacterial populations. Patients infected with bacteria expressing such resistance genes then failed treatment and remained infected or died. Growing resistance to antimicrobial agents began to take away more and more of the cures that the agents had brought.
Download or read book The Development of Antibiotic Resistance in Pseudomonas Aeruginosa written by Claudette Y. Cates and published by . This book was released on 1974 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pseudomonas Aeruginosa written by Beningo M. Penha Escudeiro and published by Nova Science Publishers. This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pseudomonas aeruginosa is a unique pathogen with a characteristic hospital epidemiology resulting in colonisation and major infectious complications. Institutions of infection control policies including guidelines on surveillance, infection control interventions and environmental decontamination are important preventive measures. In this book, the authors present current research on the symptoms of infection, antibiotic resistance and treatment of pseudomonas aeruginosa. Topics discussed include the mechanisms of antimicrobial resistance and antimicrobial treatment options; chronic pseudomonas aeruginosa infection in cystic fibrosis; and biofilm-forming ability and antimicrobial resistance of pseudomonas aeruginosa isolates of veterinary origin.
Download or read book Pseudomonas Aeruginosa written by Chee Fah Wong and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pseudomonas aeruginosa is characterized by its metabolic versatility and found ubiquitously in soil and aquatic habitats and persists survival on various surfaces of plants, animals and humans. Diversity in Pseudomonas characteristics have led to recent technological advances and lay out important avenues of research focused on the role of Pseudomonas and the molecular mechanisms of their beneficial actions. This book brings together respected P. aeruginosa experts from around the world to provide a timely, extensive and updated review of Pseudomonas research. It covers various aspects in applications of Pseudomonas in molecular engineering of genetic tools for Pseudomonas protein expression, medical and environmental fields including biofilm development, quorum sensing, heavy metal bioremediation and photodynamic therapy as well as the industrially-important lipoxygenase biocatalysis properties. This book is essential reading for scientists working with Pseudomonas and serves as a ready reference and text book for graduate students, young field microbiologists and research scientists in academia, research institutes and industry.
