Download or read book Research Progress in Alzheimer s Disease and Dementia written by Miao-Kun Sun and published by Nova Publishers. This book was released on 2007 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease (AD), the most common form of neurodegenerative disorder in the elderly, is characterised pathologically by extracellular amyloid plaques and intracellular neurofibrillary tangles, pathophysiologically by synaptic dysfunction, and clinically by a progressive decline in cognition. Currently, AD has no cure and its prevalence is predicted to triple by 2050 with the rapid increase in the ageing population, unless more effective treatments are developed. Since the publication of the second book volume, the rapid progress in the research fields of AD and dementia continues through the intensive efforts of research scientists worldwide. This third book volume contains 15 chapters, bringing together a presentation of research frontiers in current AD/dementia research. The topics include molecular genetics of AD, gene expression abnormalities in AD progression, presenilins, taupathy in AD, single -induced(neuron gene expression abnormalities in AD, intracellular A neurodegeneration, roles of lipoprotein receptors in AD onset and progression, cholesterol and tau hyperphosphorylation, AD diagnostics and therapeutic strategies, in vivo visualisation of amyloid-like structures, cathepsin B, antiamyloidogenesis and neuroprotection, environmental enrichment, Fragile X mental retardation gene and dementia, category learning in Parkinson's disease, cerebrovascular disease and dementia, and dementia and hypertension. These chapters cover current advances in our understanding of the pathogenic mechanisms underlying AD and dementia, in the diagnosis of early AD and dementia, and in the development of therapeutic agents that target memory-relevant AD pathogenesis. The book will be highly valuable to students and scientists worldwide who are interested in the scientific research progress in AD and dementia.
Download or read book Research Progress in Alzheimer s Disease and Dementia written by Miao-Kun Sun and published by . This book was released on 2016 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Research Progress in Alzheimer s Disease and Dementia written by and published by . This book was released on 2012 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Research Progress in Alzheimer s Disease and Dementia written by Miao-Kun Sun and published by Nova Science Pub Incorporated. This book was released on 2009-10-01 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease (AD), the most common form of neurodegenerative disorder in the elderly, is characterised pathologically by extracellular amyloid plaques and intracellular neurofibrillary tangles, pathophysiologically by synaptic dysfunction, and clinically by a progressive decline in cognition. Currently, AD has no cure and its prevalence is predicted to triple by 2050 with the rapid increase in the ageing population, unless more effective prevention/treatments are developed. Since the publication of the third book volume, the rapid progress in the research fields of AD and dementia continues through the intensive efforts of research scientists world-wide. This fourth book volume contains 12 chapters, bringing together a presentation of scientific frontiers in current AD/dementia research. The topics include emotional memory in AD, amyloid-B clearance, synaptic transmission-mediated regulation of amyloid-B dynamics, anti-AD immunotherapy, clinical trials of AD therapeutics using AD transgenic mouse models, roles of apolipoprotein E, chronic inflammation, cathepsins, and gelsolin in AD pathogenesis and as anti-AD therapeutic targets/agents, declarative memory impairment and hippocampal atrophy in Parkinson's disease, fronto-temporal dementia, and cognitive impairment in schizophrenia. These chapters cover current advances in our understanding of the pathogenic mechanisms underlying AD and dementia, in the diagnosis of early AD and dementia, and in the development of therapeutic agents that target memory-relevant AD pathogenesis. The book will be highly valuable to students and scientists world-wide who are interested in the scientific research progress in AD and memory disorders.
Download or read book Reducing the Impact of Dementia in America written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2022-04-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: As the largest generation in U.S. history - the population born in the two decades immediately following World War II - enters the age of risk for cognitive impairment, growing numbers of people will experience dementia (including Alzheimer's disease and related dementias). By one estimate, nearly 14 million people in the United States will be living with dementia by 2060. Like other hardships, the experience of living with dementia can bring unexpected moments of intimacy, growth, and compassion, but these diseases also affect people's capacity to work and carry out other activities and alter their relationships with loved ones, friends, and coworkers. Those who live with and care for individuals experiencing these diseases face challenges that include physical and emotional stress, difficult changes and losses in their relationships with life partners, loss of income, and interrupted connections to other activities and friends. From a societal perspective, these diseases place substantial demands on communities and on the institutions and government entities that support people living with dementia and their families, including the health care system, the providers of direct care, and others. Nevertheless, research in the social and behavioral sciences points to possibilities for preventing or slowing the development of dementia and for substantially reducing its social and economic impacts. At the request of the National Institute on Aging of the U.S. Department of Health and Human Services, Reducing the Impact of Dementia in America assesses the contributions of research in the social and behavioral sciences and identifies a research agenda for the coming decade. This report offers a blueprint for the next decade of behavioral and social science research to reduce the negative impact of dementia for America's diverse population. Reducing the Impact of Dementia in America calls for research that addresses the causes and solutions for disparities in both developing dementia and receiving adequate treatment and support. It calls for research that sets goals meaningful not just for scientists but for people living with dementia and those who support them as well. By 2030, an estimated 8.5 million Americans will have Alzheimer's disease and many more will have other forms of dementia. Through identifying priorities social and behavioral science research and recommending ways in which they can be pursued in a coordinated fashion, Reducing the Impact of Dementia in America will help produce research that improves the lives of all those affected by dementia.
Download or read book Research Progress in Alzheimer s Disease and Dementia written by Miao-Kun Sun and published by Nova Science Publishers. This book was released on 2012-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fifth book volume brings together scientific frontiers in current Alzheimer's Disease/dementia research. The book will be highly valuable to students and scientists world-wide who are interested in the scientific research progress in Alzheimer's Disease and memory disorders.
Download or read book Alzheimer s Disease Drug Development written by Jeffrey Cummings and published by Cambridge University Press. This book was released on 2022-03-31 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.
Download or read book Progress Report on Alzheimer s Disease written by and published by . This book was released on 1984 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Alzheimer s Disease written by Suzanne Corkin and published by . This book was released on 1982 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Progress Report on Alzheimer Disease written by National Institute on Aging and published by . This book was released on 1987 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Alzheimer s Disease Decoded The History Present And Future Of Alzheimer s Disease And Dementia Second Edition written by Ronald Sahyouni and published by World Scientific. This book was released on 2021-12-23 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to present, educate and inform individuals about Alzheimer's disease in a comprehensive manner. Its scope ranges from the discovery of the disease, epidemiology and basic biological principles underlying it, to advanced stem cell therapies used in the treatment of Alzheimer's. It adopts a 'global' perspective on Alzheimer's disease, and include epidemiological data and science from countries around the world.Alzheimer's disease is a rapidly growing problem seen in every country around the world. This is the first and only comprehensive book to cover Alzheimer's disease, and includes the most updated literature and scientific progress in the field of dementia and Alzheimer's disease research.Most books on the market that focus on Alzheimer's disease are targeted at caregivers as practical advice on how to deal with loved ones with the disease. This book instead is a comprehensive and popular science book that can be read by anyone with an interest in learning more about the disease.Dr Jefferson Chen MD, PhD, co-author, participated in the world's first surgical clinical trial using shunts to treat Alzheimer's disease. His first-hand involvement in a clinical trial for patients with Alzheimer's disease and experience treating Normal Pressure Hydrocephalus (NPH) which is commonly misdiagnosed as Alzheimer's disease lends a unique perspective.This book with appeal to a wide audience, regardless of their scientific or educational background.
Download or read book Progress Report on Alzheimer s Disease 1994 written by National Institute on Aging and published by . This book was released on 1993 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Oversight on Treatment of Alzheimer s Disease 1983 written by United States. Congress. Senate. Committee on Labor and Human Resources. Subcommittee on Aging and published by . This book was released on 1983 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Research and Treatment for Alzheimer s Disease written by Samuel Barrack and published by iMedPub. This book was released on 2012-01-30 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease (AD), is the most common form of dementia. There is no cure for the disease, which worsens as it progresses, and eventually leads to death. The cause and progression of Alzheimer's disease are not well understood. Research indicates that the disease is associated with plaques and tangles in the brain. Current treatments only help with the symptoms of the disease. There are no available treatments that stop or reverse the progression of the disease. As of 2012, more than 1000 clinical trials have been or are being conducted to find ways to treat the disease, but it is unknown if any of the tested treatments will work. Because AD cannot be cured and is degenerative, the sufferer relies on others for assistance. The role of the main caregiver is often taken by the spouse or a close relative. Alzheimer's disease is known for placing a great burden on caregivers; the pressures can be wide-ranging, involving social, psychological, physical, and economic elements of the caregiver's life. In developed countries, AD is one of the most costly diseases to society. Research is the only hope to present and future patients and families suffering from this devastating disorder. This book compiles some of the most interesting articles on Alzheimer's disease published by PLoS journals lately: from epidemiology and prevention to management and treatment.
Download or read book Progress in Alzheimer s and Parkinson s Diseases written by Abraham Fisher and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents the fourth ina series of international conferences related to Alzheimer's (AD) and Parkinson's (PO) diseases. The first one took place in EHat, Israel in 1985; the second in Kyoto, Japan, in 1989; and the third in Chicago, IL, USA in 1993. This book incorporates the proceedings of the Fourth International Conference on Pro gress in Alzheimer's and Parkinson's Diseases, held in EHat, Israel, on May 18-23, 1997. This Conference was the 41st in the series of annual OHOLO Conferences sponsored by the Israel Institute for Biological Research (IIBR). It was also conducted under the aus pices of the Alzheimer's Association Ronald and Nancy Reagan Research Institute, USA. The Conference was attended by 550 participants from 28 countries, representing a broad spectrum of research interests; and included a well-balanced representation from aca demia, clinical institutions and pharmaceutical industry. The four-and-one-half day meeting served as an excellent medium for surveying the current preclinical and clinical develop ments in AD, PO, and other related disorders. The scientific program was divided into 24 oral sessions and daily poster sessions. The conference culminated in a round table discus sion. There were 122 talks and 161 posters. This book incorporates a combination of both.
Download or read book Understanding Alzheimer s Disease written by Neal R. Cutler and published by Univ. Press of Mississippi. This book was released on 2010-02-11 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease has received growing attention in recent years because the affected population is growing quickly as life spans in America creep ever upward. As they near retirement, many Americans start to fear that any minor memory lapse-misplacing the keys or forgetting a name-might spell Alzheimer's. In reality such incidents are a normal part of the aging process. In Alzheimer's disease, such incidents progress to a point at which they interfere with normal daily activities on a regular basis, and memory loss becomes progressively more disabling. This book is written for anyone interested in learning more about Alzheimer's disease-people who have it, their families and caregivers, professionals who serve such people, teachers, and anyone with a general interest in the disease. An important feature of this book is clear explanation of the basic biology of the disease. Here is information about who gets the disease, how it is diagnosed, and what happens to people who have it. A large section is devoted to the subject of caring for affected individuals, including legal and financial planning advice and pointers for finding outside support services. Existing treatments are discussed along with suggestions for handling many symptoms without drugs. Understanding Alzheimer's Disease describes the most current knowledge of how and why it arises and gives information about the many avenues being explored in search of a cure. With its chapters on causes and on the search for treatments, this guide will be of interest to a wider section of the population than other books on the disease.
Download or read book Alzheimer s Disease Currently Affects an Estimated 4 Million Americans written by National Institute on Aging and published by . This book was released on 1992 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
