Download or read book Research Methodologies in Human Diabetes Part 1 written by C. E. Mogensen and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-10-12 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "RESEARCH METHODOLOGIES HUMANDIABETES 1 RMHD E-BOOK".

Download or read book Research Methodologies in Human Diabetes Part 2 written by C. E. Mogensen and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-11-23 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "RESEARCH METHODOLOGIES HUMAN DIABETES II E-BOOK".

Download or read book Clinical Diabetes Research written by Michael Roden and published by John Wiley & Sons. This book was released on 2007-08-20 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical "how to" guide for multiple methods in metabolism, with a critical and objective discussion of strengths, limitations, and appropriate applications of the described methods. Edited by the winner of the Oskar-Minkowski Prize of the EASD in 2006 Clinical trials in populations at risk of or with overt diabetes mellitus are being performed all around the world to test novel drugs and approaches to managing these diseases. During the last decade, new methods and techniques have been introduced – and are being developed further – that facilitate monitoring of metabolism and even diagnosis of certain defects in human metabolism. While some of these methods are restricted to research facilities, others are already used in clinical practice. The correct beneficial use of these methods requires knowledge of the nature of the techniques and their clinical relevance. Clinical Diabetes Research: Methods and Techniques provides summaries of established state-of-the art-techniques and introduces the new technologies, evaluating their potential in clinical diabetes research. One section compares the efficacy of all metabolic tests that measure insulin action. Another section describes methods that allow quantification of whole body and intracellular metabolic fluxes relevant to diabetes research. The final section focuses on the planning and pitfalls of clinical studies in the field of metabolism. Each chapter throughout the book combines the theoretical basis of the approach with practical recommendations. There are further chapters on the design of clinical trials and ethical considerations. The publication is timely in view of the impressive development of the methods and techniques with their application to understanding the pathophysiology of diabetes, insulin resistance syndromes, obesity, and the metabolic effects of treatment. Clinical Diabetes Research: Methods and Techniques is of great relevance for researchers (from students and post-docs to principal investigators) in the field of human metabolism, clinical endocrinologists and diabetologists who are involved in clinical studies.

Download or read book Animal Models in Diabetes Research written by Hans-Georg Joost and published by Humana Press. This book was released on 2012-08-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, human studies have made enormous contributions towards an understanding of the genetic basis of diabetes mellitus; however, most of the experimentation needed for the invention and testing of novel therapeutic approaches cannot be performed in humans. Thus, there is no alternative to appropriate animal models. In Animal Models in Diabetes Research, expert researchers explore the current status of the most important models and procedures in order to provide a timely resource in experimental diabetology. The first half of the volume serves as a comprehensive overview on our current knowledge of the pathogenesis and pathophysiology of diabetes in animal models through a series of reviews in model strains. The book then continues with vital, established protocols that are employed in the characterization and study of animal models of diabetes. As a volume in the highly successful Methods in Molecular BiologyTM series, this work contains the type of detailed description and key implementation advice necessary to achieve successful results. Authoritative and cutting-edge, Animal Models in Diabetes Research delivers essential content that will be an important resource to advance diabetes research in the years to come.

Download or read book Biomarkers of Disease written by Andrew K. Trull and published by Cambridge University Press. This book was released on 2002-06-06 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication takes a critical, evidence-based look at the efficacy of diagnostic tests which are increasingly being used to evaluate organ damage and dysfunction. The use of biomarkers is growing, with a steady stream of products being brought out by the pharmaceutical industry. Some of these assist in diagnosis, others provide a means of monitoring the state of progression of disease and the effectiveness of therapeutic options. However, in many cases the evidence which supports the use of these methods as opposed to traditional biochemical tests has not yet been demonstrated, and it is intended that this volume will help clarify the strengths and weaknesses of using these biomarkers across a wide range of applications and in the various organs of the body. This approach will provide pathologists, clinical biochemists and medical laboratory scientists with an invaluable overview of the diverse applications of biomarkers in medicine.

Download or read book Prevention of Type 2 Diabetes written by Manfred Ganz and published by John Wiley & Sons. This book was released on 2005-09-01 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a unique and comprehensive synopsis of the prevention and early diagnosis of Type 2 Diabetes. It features articles by key opinion leaders in diabetes from North America, Europe and the Asia-Pacific region who describe the gravity of the problem and the important issue of screening, including contributions on the perspectives of the International Diabetes Federation and the World Health Organization. Once patients at risk have been identified, the key issue is to prevent their progression to full-blown diabetes. Several chapters address this, particularly the difficult task of changing people’s behaviour. Prevention of the complications associated with diabetes involves more targeted interventions, which are discussed by experts in the relevant areas. This book offers both a global perspective and local solutions. Key contributors include Paul Zimmet and Pierre Lefèbvre, President of the International Diabetes Federation who has written a chapter and a foreword. Praise from the reviews: "[A]n excellent resource for professionals who want a good means for getting up to speed on the prevention angle. It is all-inclusive from many perspectives – authorship of chapters, rich reference lists, and content (...). This book is a one-stop source for understanding the state of current prevention knowledge about type 2 diabetes." —DIABETES TECHNOLOGY & THERAPEUTICS "This is a timely and helpful treatment of an important public health topic. I am unaware of any other contemporary books which address exactly this issue." —DOODY'S HEALTH SERVICES "An ambitious title, written by some of the world’s leading diabetologists, it takes a very careful approach ( ...)" —PEDIATRIC ENDOCRINOLOGY REVIEWS (PER)

Download or read book Carbohydrates in Food written by Ann-Charlotte Eliasson and published by CRC Press. This book was released on 2006-03-27 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuing in the tradition of its well-received predecessor, Carbohydrates in Food, Second Edition provides thorough and authoritative coverage of the chemical analysis, structure, functional properties, and nutritional relevance of monosaccharides, disaccharides, and polysaccharides used in food. The book combines the latest data on the analytical, physico-chemical, and nutritional properties of carbohydrates, offering a comprehensive and accessible single source of information. It evaluates the advantages and disadvantages of using various analytical methods, presents discussion of relevant physico-chemical topics that relate to the use of carbohydrates in food that allow familiarity with important functional aspects of carbohydrates; and includes information on relevant nutritional topics in relation to the use of carbohydrates in food. Carbohydrates in Food, Second Edition is an important resource for anyone working with carbohydrates in food because it provides essential information on the chemical analysis and physico-chemical properties of carbohydrates and also illustrates how they can be used in product development to increase the health benefits for the public. This New Edition Includes: Updated information on nutritional aspects of mono- and disaccharides Analytical and functional aspects of gums/hydrocolloids Nutritional aspects of plant cell wall polysaccharides, gums, and hydrocolloids Analytical, physicochemical, and functional aspects of starch Revised and expanded reference lists

Download or read book Hearing on Strategies to Increase Information on Comparative Clinical Effectiveness written by United States. Congress. House. Committee on Ways and Means. Subcommittee on Health and published by . This book was released on 2009 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Depression and Diabetes written by Wayne Katon and published by John Wiley & Sons. This book was released on 2011-06-09 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, there has been a growing awareness of the multiple interrelationships between depression and various physical diseases. The WPA is providing an update of currently available evidence on these interrelationships by the publication of three books, dealing with the comorbidity of depression with diabetes, heart disease and cancer. Depression is a frequent and serious comorbid condition in diabetes, which adversely affects quality of life and the long-term prognosis. Co-occurrent depression presents peculiar clinical challenges, making both conditions harder to manage. Depression and Diabetes is the first book devoted to the interaction between these common disorders. World leaders in diabetes, depression and public health synthesize current evidence, including some previously unpublished data, in a concise, easy-to-read format. They provide an overview of the epidemiology, pathogenesis, medical costs, management, and public health and cultural implications of the comorbidity between depression and diabetes. The book describes how the negative consequences of depression in diabetes could be avoided, given that effective depression treatments for diabetic patients are available. Its practical approach makes the book ideal for all those involved in the management of these patients: psychiatrists, psychologists, diabetologists, general practitioners, diabetes specialist nurses and mental health nurses.

Download or read book Hypoglycemia in Diabetes written by Philip Cryer and published by American Diabetes Association. This book was released on 2016-07-12 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for diabetes researchers and medical professionals who work closely with patients with diabetes, this newly updated and expanded edition provides new perspectives and direct insight into the causes and consequences of this serious medical condition from one of the foremost experts in the field. Using the latest scientific and medical developments and trends, readers will learn how to identify, prevent, and treat this challenging phenomenon within the parameters of the diabetes care regimen.

Download or read book Type 1 Diabetes in Children Adolescents and Young Adults written by Dr Ragnar Hanas and published by Class Professional Publishing. This book was released on 2022-07-11 with total page 1110 pages. Available in PDF, EPUB and Kindle. Book excerpt: When you have diabetes yourself or in your family, you must become your own expert. Equipped with the knowledge, strategies and tips provided in this easy-to-read resource, you will be fully prepared to take the best care of yourself and your diabetes. With over 40 chapters looking at topics ranging from nutrition, pregnancy and travel, to associated conditions, research and new developments, this book digs deep into the practicalities of managing and living with diabetes. This latest edition also contains advice on how to use the new hybrid insulin pump. OTHER KEY FEATURES INCLUDE: Glossary with over 150 medical terms Over 400 illustrations Over 1,000 journal and article references, plus website recommendations for further reading Details of self-help and support organisations, as well as real-life stories from people with diabetes. Medical research has conclusively proved that looking after your diabetes is key to avoiding pitfalls and long-term risks. By understanding your diabetes, you can live a full, healthy and happy life.

Download or read book Diabetes Mellitus in Children written by Mark A. Sperling and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Translational Research Methods for Diabetes Obesity and Cardiometabolic Drug Development written by Andrew J. Krentz and published by Springer. This book was released on 2014-11-29 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world is beset by a pandemic of obesity and type 2 diabetes and the need for new drugs is startlingly clear; recent years have seen a huge increase in research activity to fill this gap. The development of new drugs for diabetes and obesity must be founded upon a sound appreciation of the pathophysiology of these common disorders. The dual defects of insulin resistance and impaired insulin secretion are fundamental to the pathogenesis and progression of obesity-associated type 2 diabetes. There is a need to explain how new drugs can counter insulin resistance and insulin deficiency to a broad range of professionals, from clinical scientists active in early (and later) phase drug development to specialist physicians and increasingly primary care doctors who must tailor drug regimens to the individual patient. Clinical research methods for measuring insulin action and insulin secretion have become well-established in proof-of-mechanism studies; however, selection of the best techniques is by no means straightforward. The purpose of the book is to aid the selection of the most appropriate techniques for assessing insulin action, insulin secretion and body composition in humans (with particular reference to new drugs) in phase 1 and 2 studies and aid the understanding of drug effects and non-drug treatment strategies on key biochemical-hormonal defects of obesity and type 2 diabetes. The book will assume a working knowledge of human physiology relating to glucose metabolism and will be of interest to biomedical scientists, pharmacologists, academics involved in metabolic research and clinicians practicing in these specialties.

Download or read book Translational Research Methods in Diabetes Obesity and Nonalcoholic Fatty Liver Disease written by Andrew J. Krentz and published by Springer. This book was released on 2019-04-02 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to aid the selection of the most appropriate methods for use in early phase (1 and 2) clinical studies of new drugs for diabetes, obesity, non-alcoholic fatty liver disease (NAFLD) and related cardiometabolic disorders. Clinical research methods to assess the pharmacokinetics and pharmacodynamics of new diabetes drugs, e.g. the euglycemic clamp technique, have become well-established in proof-of-mechanism studies. However, selection of the most appropriate techniques is by no means straightforward. Moreover, the application of such methods must conform to the regulatory requirements for new drugs. This book discusses the need for new pharmacotherapies for diabetes, obesity and NAFLD and the molecular targets of drugs currently in development. Emerging technologies including functional imaging, circulating biomarkers and omics are considered together with practical and ethical issues pertaining to early phase clinical trials in subjects with cardiometabolic disorders. Translational Research Methods in Diabetes, Obesity, and Non-Alcoholic Fatty Liver Disease is of interest to biomedical scientists, pharmacologists, academics involved in metabolic research and clinicians practicing in these specialties.

Download or read book Dr Neal Barnard s Program for Reversing Diabetes written by Neal Barnard and published by Rodale Books. This book was released on 2018-02-27 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tackle diabetes and its complications for good with this newly updated edition of Dr. Neal Barnard's groundbreaking program. Revised and updated, this latest edition of Dr. Barnard’s groundbreaking book features a new preface, updates to diagnostic and monitoring standards, recent research studies, and fresh success stories of people who have eliminated their diabetes by following this life-changing plan. Before Dr. Barnard’s scientific breakthrough, most health professionals believed that once you developed diabetes, you were stuck with it—and could anticipate one health issue after another, from worsening eyesight and nerve symptoms to heart and kidney problems. But this simply is not true—Dr. Barnard has shown that it is often possible to improve insulin sensitivity and tackle type 2 diabetes by following his step-by-step plan, which includes a healthful vegan diet with plenty of recipes to get started, an exercise guide, advice about taking supplements and tracking progress, and troubleshooting tips.

Download or read book The Diabetes Code written by Dr. Jason Fung and published by Greystone Books Ltd. This book was released on 2018-04-03 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: FROM NEW YORK TIMES BESTSELLING AUTHOR DR. JASON FUNG • “The doctor who invented intermittent fasting.” —The Daily Mail “Dr. Fung reveals how [type 2 diabetes] can be prevented and also reversed using natural dietary methods instead of medications … This is an important and timely book. Highly recommended.” —Dr. Mark Hyman, author of The Pegan Diet “Dr. Jason Fung has done it again. … Get this book!” —Dr. Steven R. Gundry, author of The Plant Paradox Everything you believe about treating type 2 diabetes is wrong. Today, most doctors, dietitians, and even diabetes specialists consider type 2 diabetes to be a chronic and progressive disease—a life sentence with no possibility of parole. But the truth, as Dr. Fung reveals in this groundbreaking book, is that type 2 diabetes is reversible. Writing with clear, persuasive language, Dr. Fung explains why conventional treatments that rely on insulin or other blood-glucose-lowering drugs can actually exacerbate the problem, leading to significant weight gain and even heart disease. The only way to treat type 2 diabetes effectively, he argues, is proper dieting and intermittent fasting—not medication. “The Diabetes Code is unabashedly provocative yet practical ... a clear blueprint for everyone to take control of their blood sugar, their health, and their lives.”—Dr. Will Cole, author of Intuitive Fasting

Download or read book Life Without Diabetes written by Roy Taylor and published by HarperCollins. This book was released on 2020-03-17 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE US EDITION OF THE INTERNATIONAL BESTSELLER A momentous medical breakthrough —a scientifically proven program for managing and reversing Type 2 Diabetes at any stage of health. The fastest growing disease in the world, Type 2 diabetes has long been regarded as an incurable, lifelong condition that becomes progressively worse over time, resulting in pain, loss of vision, amputation, and even premature death. But there is hope. For more than four decades, Dr. Roy Taylor has been studying the causes of diabetes. In 2017, he had a breakthrough: he found scientific proof that Type 2 diabetes is not only reversible, but that anyone following a simple regimen can prevent and cure it. Dr. Taylor’s research shows that Type 2 diabetes is caused by too much fat in the liver and pancreas, which interferes with both organs’ normal functioning. By losing less than 1 gram of fat, the liver and organ can begin to perform as they were designed to once again—thus beginning the reversal process. The most efficient way to shed fat from the liver and pancreas is to lose weight as quickly as possible. Life Without Diabetes makes it easy for people to cut back on their daily calorie intake and avoid the two big problems of dieting—hunger and choice—and lose up to 35 pounds in just eight weeks. Thanks to Dr. Taylor, we can now fundamentally change how we treat and prevent this debilitating and all-too-common disease forever.