Download or read book Principles and Practice of Clinical Research written by John I. Gallin and published by Elsevier. This book was released on 2011-04-28 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers.*Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research*Delves into data management and addresses how to collect data and use it for discovery*Contains valuable, up-to-date information on how to obtain funding from the federal government

Download or read book Principles of Planning Evaluation and Research for Health Care Programs written by () (Kay) M. M. M. Perrin and published by Jones & Bartlett Learning. This book was released on 2020-10-12 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Planning, Evaluation, and Research for Health Care Programs provides a basic understanding of the importance of and the key approaches used to conduct health program research and evaluations. The book also examines ethical and cultural competency issues unique to conducting evaluations. Additionally, it offers an introduction to systems thinking and its implications for evaluating the impact of interventions. Written with the undergraduate in mind, this book is ideal for students pursuing a wide spectrum of health careers. Through activities and case studies, readers will gain a solid foundation for understanding all aspects of evaluation while developing the critical thinking skills needed to dissect peer-reviewed publications as well as popular media health claims.

Download or read book Principles of Medical Education written by Tejinder Singh and published by Jaypee Brothers Medical Publishers. This book was released on 2020-10-07 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Principles of Translational Science in Medicine written by Martin Wehling and published by Academic Press. This book was released on 2015-04-02 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine. - Provides an in-depth description of novel tools for the assessment of translatability of trials to balance risk and improve projects at any given stage of product development - New chapters deal with translational issues in the fastest growing population (the elderly), case studies, translatability assessment tools, and advances in nanotherapies - Details IPR issues of translation, especially for public-private-partnerships - Contains contributions from world leaders in translational medicine, including the former NIH director and authorities from various European regulatory institutions

Download or read book Health Science Promotion Act of 1979 written by United States. Congress. Senate. Committee on Labor and Human Resources. Subcommittee on Health and Scientific Research and published by . This book was released on 1979 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book DHEW Health Research Principles written by National Institutes of Health (U.S.) and published by . This book was released on 1979 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Principles of Systems Science written by George E. Mobus and published by Springer. This book was released on 2014-11-10 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: This pioneering text provides a comprehensive introduction to systems structure, function, and modeling as applied in all fields of science and engineering. Systems understanding is increasingly recognized as a key to a more holistic education and greater problem solving skills, and is also reflected in the trend toward interdisciplinary approaches to research on complex phenomena. While the concepts and components of systems science will continue to be distributed throughout the various disciplines, undergraduate degree programs in systems science are also being developed, including at the authors’ own institutions. However, the subject is approached, systems science as a basis for understanding the components and drivers of phenomena at all scales should be viewed with the same importance as a traditional liberal arts education. Principles of Systems Science contains many graphs, illustrations, side bars, examples, and problems to enhance understanding. From basic principles of organization, complexity, abstract representations, and behavior (dynamics) to deeper aspects such as the relations between information, knowledge, computation, and system control, to higher order aspects such as auto-organization, emergence and evolution, the book provides an integrated perspective on the comprehensive nature of systems. It ends with practical aspects such as systems analysis, computer modeling, and systems engineering that demonstrate how the knowledge of systems can be used to solve problems in the real world. Each chapter is broken into parts beginning with qualitative descriptions that stand alone for students who have taken intermediate algebra. The second part presents quantitative descriptions that are based on pre-calculus and advanced algebra, providing a more formal treatment for students who have the necessary mathematical background. Numerous examples of systems from every realm of life, including the physical and biological sciences, humanities, social sciences, engineering, pre-med and pre-law, are based on the fundamental systems concepts of boundaries, components as subsystems, processes as flows of materials, energy, and messages, work accomplished, functions performed, hierarchical structures, and more. Understanding these basics enables further understanding both of how systems endure and how they may become increasingly complex and exhibit new properties or characteristics. Serves as a textbook for teaching systems fundamentals in any discipline or for use in an introductory course in systems science degree programs Addresses a wide range of audiences with different levels of mathematical sophistication Includes open-ended questions in special boxes intended to stimulate integrated thinking and class discussion Describes numerous examples of systems in science and society Captures the trend towards interdisciplinary research and problem solving

Download or read book DHEW Health Research Principles Documents relating to the development of draft health research principles for the Department of Health Education and Welfare App C Public testimony on the draft DHEW health research principles written by National Institutes of Health (U.S.). and published by . This book was released on 1979 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book DHEW Health Research Principles Documents relating to the development of final health research principles for the Department of Health Education and Welfare written by National Institutes of Health (U.S.) and published by . This book was released on 1979 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Social Science Research written by Anol Bhattacherjee and published by CreateSpace. This book was released on 2012-04-01 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to introduce doctoral and graduate students to the process of conducting scientific research in the social sciences, business, education, public health, and related disciplines. It is a one-stop, comprehensive, and compact source for foundational concepts in behavioral research, and can serve as a stand-alone text or as a supplement to research readings in any doctoral seminar or research methods class. This book is currently used as a research text at universities on six continents and will shortly be available in nine different languages.

Download or read book DHEW Health Research Principles December 1978 August 1979 written by National Institutes of Health (U.S.) and published by . This book was released on 1979 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book DHEW Health Research Principles pt 1 Documents relating to the development of draft health research principles for the Department of Health Education and Welfare written by National Institutes of Health (U.S.) and published by . This book was released on 1979 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Clinical Ethics written by Albert R. Jonsen and published by McGraw-Hill Companies. This book was released on 1992 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Ethics introduces the four-topics method of approaching ethical problems (i.e., medical indications, patient preferences, quality of life, and contextual features). Each of the four chapters represents one of the topics. In each chapter, the authors discuss cases and provide comments and recommendations. The four-topics method is an organizational process by which clinicians can begin to understand the complexities involved in ethical cases and can proceed to find a solution for each case.

Download or read book Sharing Clinical Trial Data written by Institute of Medicine and published by National Academies Press. This book was released on 2015-04-20 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research-from funders, to researchers, to journals, to physicians, and ultimately, to patients.

Download or read book DHEW Health Research Principles April December 1978 written by National Institutes of Health (U.S.) and published by . This book was released on 1979 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nursing Research written by Denise F. Polit and published by Lippincott Williams & Wilkins. This book was released on 1983 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Sixth Edition of this classic text maintains its place as the "Gold Standard" of nursing research. Nationally and internationally known, respected and used, the text provides readers with the skills they need to design and implement a research investigation and critically evaluate published research reports. Now completely revised and updated to reflect the latest trends in quantitative and qualitative research, this essential guide offers a focused, "how-to" approach. New in this edition: expanded discussion of qualitative approaches; demonstration of qualitative and quantitative approaches working together; charts and tables offer description of qualitative approaches; stronger emphasis on the "hands-on, how-to" methodology; more in-depth examination of reasearch difference; research more powerful research utilization.

Download or read book Responsible Science written by Committee on Science, Engineering, and Public Policy (U.S.). Panel on Scientific Responsibility and the Conduct of Research and published by National Academies. This book was released on 1992 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Responsible Science is a comprehensive review of factors that influence the integrity of the research process. Volume I examines reports on the incidence of misconduct in science and reviews institutional and governmental efforts to handle cases of misconduct. The result of a two-year study by a panel of experts convened by the National Academy of Sciences, this book critically analyzes the impact of today's research environment on the traditional checks and balances that foster integrity in science. Responsible Science is a provocative examination of the role of educational efforts; research guidelines; and the contributions of individual scientists, mentors, and institutional officials in encouraging responsible research practices.