Download or read book Report on Evaluation of Fap Financial Assistance Policy written by and published by . This book was released on 1984 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Report on Evaluation of FAP written by J. Isaken and published by . This book was released on 1984 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Financial Assistance Policy written by Botswana. Ministry of Finance and Development Planning and published by . This book was released on 1984 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The FAP Model and Its Application in the Appraisal of ICT Projects written by F. Lefley and published by Palgrave Macmillan. This book was released on 2015-06-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the 2005 publication The Financial Appraisal Profile Model , this book discusses how the FAP model can present an integrated process for the appraisal of financial and strategic benefits and the assessment of risk in ICT (Information Communication Technology) project proposals.

Download or read book Colorectal Cancer Screening written by Joseph Anderson, MD and published by Springer Science & Business Media. This book was released on 2011-04-23 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal Cancer Screening provides a complete overview of colorectal cancer screening, from epidemiology and molecular abnormalities, to the latest screening techniques such as stool DNA and FIT, Computerized Tomography (CT) Colonography, High Definition Colonoscopes and Narrow Band Imaging. As the text is devoted entirely to CRC screening, it features many facts, principles, guidelines and figures related to screening in an easy access format. This volume provides a complete guide to colorectal cancer screening which will be informative to the subspecialist as well as the primary care practitioner. It represents the only text that provides this up to date information about a subject that is continually changing. For the primary practitioner, information on the guidelines for screening as well as increasing patient participation is presentedd. For the subspecialist, information regarding the latest imaging techniques as well as flat adenomas and chromoendoscopy are covered. The section on the molecular changes in CRC will appeal to both groups. The text includes up to date information about colorectal screening that encompasses the entire spectrum of the topic and features photographs of polyps as well as diagrams of the morphology of polyps as well as photographs of CT colonography images. Algorithms are presented for all the suggested guidelines. Chapters are devoted to patient participation in screening and risk factors as well as new imaging technology. This useful volume explains the rationale behind screening for CRC. In addition, it covers the different screening options as well as the performance characteristics, when available in the literature, for each test. This volume will be used by the sub specialists who perform screening tests as well as primary care practitioners who refer patients to be screened for colorectal cancer.

Download or read book Genetics of Colorectal Cancer written by John D. Potter and published by Springer. This book was released on 2008-12-08 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic susceptibility refers to how variations in a person’s genes increase or decrease his or her susceptibility to environmental factors, such as chemicals, radiation and lifestyle (diet and smoking). This volume will explore the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers. Topics will include germline susceptibility, including Mendelian patterns of inheritance and gene-environment interactions that lead to cancer etiology.

Download or read book Functional Analytic Psychotherapy written by Mavis Tsai and published by Routledge. This book was released on 2012-03-12 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: How can I supercharge the therapy I currently use? This volume distils the core principles, methods, and vision of the approach. Each Functional Analytic Psychotherapy (FAP) principle is presented in terms of its intended purpose and is clearly linked to the underlying theory, thus providing clinicians with a straightforward guide for when and how to apply each technique. FAP embraces awareness, courage, and love as integral to the treatment process. Part I of this volume reviews the history of FAP and the basic behavioral principles on which it is based. Part II provides an easy to use step-by-step guide to the application of FAP techniques. FAP is an approach undergoing a renaissance, and this volume uniquely summarizes the full history, theory, and techniques of FAP, resulting in a handbook perfect for clinicians and graduate students with or without a behavioural background.

Download or read book Ferri s Clinical Advisor 2019 E Book written by Fred F. Ferri and published by Elsevier Health Sciences. This book was released on 2018-05-26 with total page 7409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated annually with the latest developments in diagnosis and treatment recommendations, Ferri’s Clinical Advisor uses the popular "5 books in 1" format to organize vast amounts of information in a clinically relevant, user-friendly manner. This efficient, intuitive format provides quick access to answers on more than 900 common medical conditions, including diseases and disorders, differential diagnoses, and laboratory tests – all updated by experts in key clinical fields. Updated algorithms and current clinical practice guidelines help you keep pace with the speed of modern medicine. Contains significant updates throughout, with more than 500 new figures, tables, and boxes added to this new edition. Features 17 all-new topics including opioid overdose, obesity-Hypoventilation syndrome, acute pelvic pain in women, new-onset seizures, and eosinophilic esophagitis, among many others. Provides current ICD-10 insurance billing codes to help expedite insurance reimbursements. Includes cross-references, outlines, bullets, tables, boxes, and algorithms to help you navigate a wealth of clinical information. Offers access to exclusive online content: more than 90 additional topics; new algorithms, images, and tables; EBM boxes; patient teaching guides, color images, and more.

Download or read book PET CT in Lung Cancer written by Archi Agrawal and published by Springer. This book was released on 2018-02-16 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise, excellently illustrated pocket book provides an up-to-date summary of the science and practice of PET/CT imaging in lung cancer. The coverage encompasses the entire spectrum of lung cancer – pathology, radiological and PET/CT imaging, and management. Readers will also find information on the physics of PET and its use in respiratory gating and radiotherapy planning. The highlights of the book are the exquisite depiction of normal variants, pitfalls, and artifacts and a pictorial atlas of the various types of lung cancer and their manifestations. The contributing authors are well-known and experienced oncologists, pathologists, radiologists, and nuclear physicians. This book has been compiled under the auspices of the British Nuclear Medicine Society. It will be of high value for nuclear physicians, radiologists, referring clinicians and oncologists, and paramedical staff working in these fields

Download or read book Third Evaluation of the Financial Assistance Policy FAP written by Phaleng Consultancies and published by . This book was released on 1995 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Identification and clinical evaluation of senescence associated markers to distinguish melanocytic nevi from melanomas written by Kyriakos Orfanidis and published by Linköping University Electronic Press. This book was released on 2019-12-19 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Melanoma is a form of cancer that develops in melanocytes. While it represents only 5% of skin malignancies, it is the most aggressive and lethal. Benign proliferation of these cells form the melanocytic nevi. The definitive diagnosis of melanocytic nevi or melanoma lesions is histopathologic. However, it is estimated that a correct diagnosis is established by means of standard skin biopsy in only 83% of the melanocytic lesions; of the remaining cases 8% and 9% are overinterpreted (false positives) and under-interpreted (false negatives), respectively. This underscores the importance of additional diagnostic tests. Since cellular senescence is considered to be a tumor suppressive mechanism, immuno-histochemistry using senescence markers has been suggested for the evaluation of difficult melanocytic lesions; however, the routinely used senescence markers lack the ability to distinguish nevi from melanoma. The general aim of this thesis is therefore to identify novel senescence markers that may aid in melanoma diagnosis. In study I, we established a cellular model with nevus-mimicking characteristics consisting in primary melanocytes that become senescent. Transcriptomic analysis allowed expanding the set of senescence-associated markers that could distinguish nevi from melanoma and identifying tubulin ?-3 as a potential diagnostic marker. Depletion of tubulin ?-3 and pretreatment with tubulin destabilizing drugs in melanocytes and melanoma cells induced a senescence-like phenotype in vitro. In particular, reduced migration capacity and induction of cell cycle arrest in G2/M phase of the cell cycle was demonstrated. In study II, a potential inter-cellular signaling pathway between melanoma cells and stromal fibroblasts, that might facilitate melanoma invasion, was investigated. Ultraviolet (UV) radiation was shown, both in melanoma cells and fibroblasts, to promote the release and activation of TGF-?1 and subsequent increase in expression of the serine protease FAP-?, a protein that plays role in extracellular matrix degradation and therefore facilitates the invasion of melanoma cells. Such mechanism was not functional in senescent melanocytes. In study III, it was shown that tubulin ?-3 immunostaining aids in the diagnosis of nevi and melanomas. The diagnostic criterium was the tubulin ?-3 gradient within the melanocytic nevi that was no longer apparent in melanoma. Different patterns of tubulin ?-3 immunostaining in melanoma were described, dermoscopy-immunohistochemistry associations were found, specific dermoscopic features highlighted, and the prognostic value of this tubulin ?-3 marker was examined. The progression rate in patients whose melanomas had areas with loss of tubulin ?-3 was 4 times higher than in patients without this feature, although statistical significance could not be reached (p=0.06). In conclusion, transcriptomic analysis expanded the set of senescence-associated markers that could distinguish nevi from melanoma and identified tubulin ?-3 as novel immunohistochemistry marker shown to have diagnostic and probably prognostic value. From a mechanistical point of view, ultraviolet radiation was shown to promote not only the formation of melanoma but also its progression by increasing a cathepsin-TGF-?1-FAP-? pathway resulting in extracellular matrix degradation. Malignt melanom är en form av cancer som utvecklas i melanocyter, de celler i huden som bildar pigmentet melanin. Även om malignt melanom endast utgör 5% av alla hudcancrar, är den den mest aggressiva och dödliga. Godartad ansamling av melanocyter bildar en leverfläck eller ett sk nevus. Vid minsta misstanke om melanom, opereras nevuset bort och analyseras i mikroskop. Det uppskattas dock att en korrekt diagnos fastställs endast i 83% av de bortopererade lesionerna. Av de återstående fallen är 8% övertolkade och 9% undertolkade. Detta understryker vikten av att förbättra melanomdiagnostik. Melanocyter i nevi anses i motsats till melanom ha avtagande förmåga att föröka sig efter ett visst antal celldelningar på grund av cellåldrande. Påvisande av cellåldrande-markörer skulle därför kunna förbättra diagnostiken av svårbedömda lesioner. De idag rutinmässigt använda cellåldrande-markörerna saknar dock förmåga att skilja nevi från melanom. Det övergripande syftet med denna avhandling var därför att försöka identifiera nya cellåldrande-markörer för att förbättra melanom-diagnostiken. I studie I etablerade vi en cellmodell med nevus-efterliknande egenskaper bestående av melanocyter som åldras. Med genuttryck-analys studerades cellåldrande-markörer som kunde skilja nevi från melanom. Proteinet tubulin ?-3 identifierades som en potentiell diagnostisk markör. Minskning av tubulin ?-3 och förbehandling med tubulin-destabiliserande läkemedel i melanocyter visade sig inducera ett tillstånd som liknar cellåldrandet. I studie II undersöktes en signalväg mellan melanomceller och fibroblaster, som kan underlätta melanomcellers förmåga att infiltrera och aktivt förstöra omgivande vävnad. Fibroblaster är en typ av bindvävsceller i läderhuden som tillverkar ämnen som finns mellan celler, s.k. extracellulär matrix. Ultraviolett (UV)-strålning visade sig, både i melanomceller och fibroblaster, främja signalvägen som resulterar i ökat proteinuttryck av FAP-?, ett protein som bidrar till nedbrytning av extracellulär matrix vilket kan underlätta infiltration av melanomceller. En sådan signalväg var inte funktionell i åldrande melanocyter. I studie III visade vi att proteinet tubulin ?-3 är en markör som underlättar diagnostik av nevi respektive melanom. Det diagnostiska kriteriet var tubulin ?-3 gradienten som kunde ses i nevi men som ej var synligt i melanom. Olika mönster av tubulin ?-3 analys i melanom beskrevs, kliniska associationer hittades och värdet av denna markör för att förutsäga sjukdomens förlopp undersöktes. Melanompatienter, vars melanom hade områden med förlust av tubulin ?-3, hade fyra gånger högre progressionstakt av sjukdomen jämfört med patienter utan detta mönster. Sammanfattningsvis studerade vi cellåldrande-markörer som kunde skilja nevi från melanom och vi identifierade proteinet tubulin ?-3 som en markör med diagnostiskt och förmodligen prognostiskt värde. Vi visade att ultraviolett strålning inte bara främjar melanombildning utan också dess progression genom att öka en signalväg mellan melanomceller och fibroblaster som resulterar i extracellulär matrixnedbrytning.

Download or read book Recommendations and Reports written by Administrative Conference of the United States and published by . This book was released on 1968 with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Journal of Rehabilitation R D written by and published by . This book was released on 1995 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Financial Appraisal Profile Model written by Frank Lefley and published by Palgrave Macmillan. This book was released on 2005-07-22 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes an integrated capital appraisal procedure that is commanding increasing attention in the academic world, industry, commerce and the professions. Formal techniques are widely used for the analysis of capital projects but are limited by their scope and by the difficulty in interpreting the significance of the results they produce. The FAP model overcomes these difficulties by creating an integrated process for the appraisal of the financial and strategic benefits of new project proposals and for the assessment of risk.

Download or read book Hereditary Colorectal Cancer written by Miguel A. Rodriguez-Bigas and published by Springer Science & Business Media. This book was released on 2010-09-10 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. The national annual incidence rate of colorectal cancer is approximately 148,000+, striking slightly more females than males. The lifetime risk of colorectal cancer is 5-6%, however patients with a familial risk (with two or more first or second degree relatives) make up 20% of the patients. Persons who carry genetic mutations linked to hereditary colorectal cancer are the most likely to develop the disease.

Download or read book Journal of Rehabilitation Research and Development written by and published by . This book was released on 1994 with total page 948 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Inflammatory Bowel Disease and Familial Adenomatous Polyposis written by Gian Gaetano Delaini and published by Springer Science & Business Media. This book was released on 2007-03-06 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammatory bowel disease (IBD) and familial adenomatous polyposis (FAP) are complex diseases. Despite increased knowledge on the pathophysiological process, many aspects remain rather unclear, especially concerning IBD. This book gathers current methods of treatment of these diseases and also presents the management of their complications. The authors give a comprehensive overview of the newer therapies to bring readers up to date.