Download or read book Regulatory Function of Adenosine written by Robert M. Berne and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: The principal objective of this symposium was to bring together investigators from all over the world who work in diverse areas of research but share a common interest in the physiologic and pathophysiologic funetions of the nueleoside adenosine. In 1978, the "International Conference on Physiological and Regulatory Funetions of Adenosine and Adenine Nueleotides," held in Banff, Canada, served as an effective catalyst in enabling scientists with differ ent points of view to exchange information and ideas on this subject. Since 1978, the amount of research on different as peets of adenosine metabolism, mechanism of action, transport, and function in various tissues (in both nor maI and abnormal states) has increased exponentially, and there was an urgent need for another meeting for updating information on this burgeoning subject. The focus of the meeting was extremely sharp, but the scope of the subject material was very broad. Scientists categorized as chemists, biochemists, physiologists, pharmacologists, and immunologists, working with cells and eelI fragments, with tissues such as heart, brain, musele, fat, kidney, and with human beings having immune deficiency diseases participated in the sym posium. They had an opportunity to air their differences, reinforce their areas of agreement, and, most important, they educated each other with respeet to research on adenosine; it is hoped that they also enriched their own research programs from the information they gained from their fellow participants.
Download or read book Regulatory Function of Adenosine written by Robert M. Berne and published by . This book was released on 1983 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Regulatory Function of Adenosine written by Robert M. Berne and published by . This book was released on 1983 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Physiological and Regulatory Functions of Adenosine and Adenine Nucleotides written by Hans P. Baer and published by New York : Raven Press. This book was released on 1979 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Adenosine and Adenine Nucleotides As Regulators of Cellular Function written by John W. Phillis and published by CRC Press. This book was released on 1991-06-14 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides valuable information for investigators interested in the signaling and regulatory functions of adenosine and the adenine nucleotides. Topics covered in this comprehensive volume include the historical development of research on adenosine and adenosine triphosphate; various aspects of the formation, metabolism, release, transport, and receptors for endogenous adenosine and the adenosine triphosphate; functions of purines at the cellular level; the role of adenosine in the regulation of flow in different vascular beds; and angiogenesis. The book also addresses the purinergic regulation of the cardiac, renal, gastro-intestinal, and central nervous system, as well as potential therapeutic avenues for purine use. The book will be valuable to physiologists, pharmacologists, and other basic and clinical scientists interested in updating their knowledge of the expanding biological roles of these substances.
Download or read book Intestinal Motility written by Jan D. Huizinga and published by . This book was released on 1981 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Adenosine Receptors in Neurodegenerative Diseases written by David Blum and published by Academic Press. This book was released on 2017-03-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adenosine Receptors in Neurodegenerative Diseases covers the role of adenosine receptors in brain function, also focusing on related methodologies and perspectives in therapeutics. The book provides an up-to-date overview by the best specialists in the field, helping readers consider the importance of adenosine and expand the global impact and visibility of adenosine research in the CNS field. Chapters include adenosine biology and signaling, gene regulation, control of motor function, and novel adenosine-based therapies in the CNS. It is an ideal resource for researchers, advanced graduate students, clinicians, and industry scientists working in the fields of clinical neuroscience and molecular and cellular neuroscience.
Download or read book Physiological and Regulatory Functions of Adenosine and Adenine Nucleotides written by and published by . This book was released on 1979* with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Regulatory Role of Adenosine 3 5 phosphate written by and published by . This book was released on 1961 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Regulation of Coronary Blood Flow written by Michitoshi Inoue and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
Download or read book Adenosine Receptors and Parkinson s Disease written by Hiroshi Kase and published by Academic Press. This book was released on 1999-10-15 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease. This book covers how the Parkinson's disease antagonist drug, A2A, has been researched, developed, and tested. It is an essential book for researchers interested in the basal ganglia, purine biology, and Parkinson's Disease. Discusses the discovery and development of a novel non-dopaminomimetic agent for Parkinson's disease Provides the first definitive overview of adenosine antagonists and their role in the treatment of Parkinson's disease Presents a new mechanism of action of adenosine A2A receptor antagonists in motor function Proposes a hypothesis of adenosine A2A receptor function in the striatum Comprehensive overview of adenosine, its receptor subtypes, their antagonists/agonists from biochemistry, molecular biology, medicinal chemistry, physiology, pharmacology, and neurochemistry viewpoints
Download or read book The Regulation of Cardiac Fibroblast Function by Adenosine and the the Role of A2 Receptors written by Lala Makhsudova and published by . This book was released on 2001 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Adenosine Receptors in Health and Disease written by Constance N. Wilson and published by Springer Science & Business Media. This book was released on 2009-07-28 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since their discovery approximately 25 years ago, adenosine receptors have now emerged as important novel molecular targets in disease and drug discovery. These proteins play important roles in the entire spectrum of disease from inflammation to immune suppression. Because of their expression on a number of different cell types and in a number of different organ systems they play important roles in specific diseases, including asthma, rheumatoid arthritis, Parkinson’s disease, multiple sclerosis, Alzheimer’s disease, heart disease, stroke, cancer, sepsis, and obesity. As a result of intense investigations into understanding the molecular structures and pharmacology of these proteins, new molecules have been synthesized that have high specificity for these proteins and are now entering clinical trials. These molecules will define the next new classes of drugs for a number of diseases with unmet medical needs.
Download or read book The Adenosine Receptors written by Pier Andrea Borea and published by Humana Press. This book was released on 2018-07-28 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book traces the history of adenosine receptor research from molecular biology to medicinal chemistry to behavior, including their implications in disease and potential strategies as therapeutic targets. It provides the reader with a comprehensive overview of the adenosine receptors that includes information on all subtypes - A1, A2A, A2B and A3. Aspects addressed include the most up to date information on their functional distribution in the nervous and peripheral systems, behavioral roles in inflammation, cancer, pain and neurological diseases such as Huntington’s disease, Epilepsy, Parkinson’s disease and Alzheimer’s disease.
Download or read book Adenosine Signaling Mechanisms written by Vickram Ramkumar and published by . This book was released on 2015 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: The role of adenosine and adenosine receptors in normal cell physiology and in diseases has been an area of active research over the last several decades. The field has advanced from the use of limited tools to examine receptor signaling and function to the use of various molecular and receptor knockout techniques to examine the details of the expression and functions and regulation of these receptors. This book highlights important milestones in adenosine receptor research and reviews recent findings from experts in different research areas. Several research areas, ranging from cardiovascular, cancer, and central nervous system research are discussed. Several of the chapters describe how understanding the basic cellular mechanisms regulated by adenosine could lead to the development of important therapeutics. The editors, Vickram Ramkumar and Roberto Paes-de-Carvalho, have published extensively on adenosine receptors for more than two decades and are still active in this field of research. It is our hope that this book provides an excellent synopsis of the current status of adenosine receptor research which would be valuable for researchers in the field and as a reference source for clinicians and others interested in this area.
Download or read book Transcriptional Regulation of the Adenosine Deaminase Gene written by Anthony G. Brickner and published by . This book was released on 1998 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Adenosine Receptors written by Gyorgy Hasko and published by CRC Press. This book was released on 2006-07-20 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: After a century of research, several lines of evidence now indicate that the ability of adenosine to directly control inflammatory cells has a major impact on the functions of the inflammatory and immune systems. Consequently, many promising therapeutic approaches are beginning to emerge that focus on the modulation of adenosine, including the deve
