Download or read book Regulation of Skeletal Muscle Fatty Acid Metabolism Following Acute and Chronic Exercise written by University of Guelph. Department of Human Biology and Nutritional Sciences and published by . This book was released on 2008 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Skeletal Muscle Metabolism in Exercise and Diabetes written by Erik A. Richter and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Copenhagen Muscle Research Centre was founded in 1994 with the support of a grant from the Danish National Research Foundation. Among the goals for the Centre is the organization of research symposia, with the aim of bringing a limited number ofintemation ally renowned scientists together to discuss the latest developments and perspectives in their field. The first Copenhagen Muscle Research Centre Conference was held in 1995 and dealt with cardiovascular regulation. The Second Copenhagen Muscle Research Centre Confer ence was held from October 23-26, 1997. The topic of the Symposium was Muscle Metabo lism: Regulation, Exercise, and Diabetes. Seventy invited scientists from all over the world discussed their latest research related to skeletal muscle metabolism. The speakers were asked to expand on their presentations and to write short, but comprehensive, chapters about their given topics. The result is 28 peer-reviewed and edited chapters covering many if not all aspects of muscle energy metabolism related to exercise and diabetes. Emphasis is on regulation of glucose and fatty acid metabolism and the mechanisms regulating their use as fuels for the muscle during exercise. In addition, abnormalities in the regulation of glucose metabolism in the diabetic state are described. However, amino acid and protein metabolism are also thoroughly discussed. We believe that this volume brings an unparralleled, up to date, and comprehensive review of the frontiers in muscle metabolism. Erik A.
Download or read book Exercise Metabolism written by Mark Hargreaves and published by Human Kinetics. This book was released on 2006 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive reference for biochemists, sport nutritionists, exercise physiologists, and graduate students in those disciplines. Provides information on the metabolic processes that take place during exercise, examining in depth the mobilization and utilization of substrates during physical activity. Focuses primarily on the skeletal muscle, but also discusses the roles of the liver and adipose tissue. Annotation copyright by Book News, Inc., Portland, OR
Download or read book Hormones Metabolism and the Benefits of Exercise written by Bruce Spiegelman and published by Springer. This book was released on 2018-03-07 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.
Download or read book Mitochondria in Obesity and Type 2 Diabetes written by Beatrice Morio and published by Academic Press. This book was released on 2019-04-26 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key concepts on topics such as the role of mitochondria in adipose tissue, cancer, cardiovascular comorbidities, skeletal muscle, the liver, kidney, and more. This book is a must-have reference for students and educational teams in biology, physiology and medicine, and researchers. Synthesizes actual knowledge on mitochondrial function Provides an integrated vision of each tissue in the etiology of obesity and type 2 diabetes Identifies the interactive networks that involve alteration in mitochondrial mass and function in disease progression Highlights the role played by mitochondria in the prevention and treatment of obesity and type 2 diabetes
Download or read book The Role of Protein and Amino Acids in Sustaining and Enhancing Performance written by Institute of Medicine and published by National Academies Press. This book was released on 1999-09-15 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is a commonly held belief that athletes, particularly body builders, have greater requirements for dietary protein than sedentary individuals. However, the evidence in support of this contention is controversial. This book is the latest in a series of publications designed to inform both civilian and military scientists and personnel about issues related to nutrition and military service. Among the many other stressors they experience, soldiers face unique nutritional demands during combat. Of particular concern is the role that dietary protein might play in controlling muscle mass and strength, response to injury and infection, and cognitive performance. The first part of the book contains the committee's summary of the workshop, responses to the Army's questions, conclusions, and recommendations. The remainder of the book contains papers contributed by speakers at the workshop on such topics as, the effects of aging and hormones on regulation of muscle mass and function, alterations in protein metabolism due to the stress of injury or infection, the role of individual amino acids, the components of proteins, as neurotransmitters, hormones, and modulators of various physiological processes, and the efficacy and safety considerations associated with dietary supplements aimed at enhancing performance.
Download or read book Muscle Metabolism During Exercise written by Bengt Pernow and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Howard G. Knuttgen of Biology, Boston University, 2 Cummington Department Street, Boston, 02215 Massachusetts, USA The relationship of the formation of lactate acid to skeletal muscle energy release in exercising humans was first explored by A. V. Hill and co-workers (2l, 22). The term "oxygen debt" was suggested by them to describe the excess oxygen consumption of recovery which they felt was closely related. A combination of their work and the earlier work of Krogh and Lindhard (35) re sulted at that time in the belief that a certain amount of energy release during the transition from rest to exercise was provided by a non-aerobic source, glycolysis. The resulting accumulation of lactic acid (as lactate) in the body required an extra con sumption during recovery for its oxidative removal. Jervell (24) subsequently showed that, in exercise, the greatest accumulation in blood took place during the first few minutes. He felt that the blood lactate increase was due to a shortage of oxygen during the transition period. The observation was also made for the first time that the increased level of lac tate due to exercise could be made to fall faster if mild exercise was employed by the subjects in place of sedentary recovery. The work of Margaria, Edwards and Dill (40) appeared in 1933. They observed that exercise (treadmill running) could be carried on at low levels without significant changes in resting levels of blood lactate.
Download or read book Skeletal Muscle Circulation written by Ronald J. Korthuis and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this treatise is to summarize the current understanding of the mechanisms for blood flow control to skeletal muscle under resting conditions, how perfusion is elevated (exercise hyperemia) to meet the increased demand for oxygen and other substrates during exercise, mechanisms underlying the beneficial effects of regular physical activity on cardiovascular health, the regulation of transcapillary fluid filtration and protein flux across the microvascular exchange vessels, and the role of changes in the skeletal muscle circulation in pathologic states. Skeletal muscle is unique among organs in that its blood flow can change over a remarkably large range. Compared to blood flow at rest, muscle blood flow can increase by more than 20-fold on average during intense exercise, while perfusion of certain individual white muscles or portions of those muscles can increase by as much as 80-fold. This is compared to maximal increases of 4- to 6-fold in the coronary circulation during exercise. These increases in muscle perfusion are required to meet the enormous demands for oxygen and nutrients by the active muscles. Because of its large mass and the fact that skeletal muscles receive 25% of the cardiac output at rest, sympathetically mediated vasoconstriction in vessels supplying this tissue allows central hemodynamic variables (e.g., blood pressure) to be spared during stresses such as hypovolemic shock. Sympathetic vasoconstriction in skeletal muscle in such pathologic conditions also effectively shunts blood flow away from muscles to tissues that are more sensitive to reductions in their blood supply that might otherwise occur. Again, because of its large mass and percentage of cardiac output directed to skeletal muscle, alterations in blood vessel structure and function with chronic disease (e.g., hypertension) contribute significantly to the pathology of such disorders. Alterations in skeletal muscle vascular resistance and/or in the exchange properties of this vascular bed also modify transcapillary fluid filtration and solute movement across the microvascular barrier to influence muscle function and contribute to disease pathology. Finally, it is clear that exercise training induces an adaptive transformation to a protected phenotype in the vasculature supplying skeletal muscle and other tissues to promote overall cardiovascular health. Table of Contents: Introduction / Anatomy of Skeletal Muscle and Its Vascular Supply / Regulation of Vascular Tone in Skeletal Muscle / Exercise Hyperemia and Regulation of Tissue Oxygenation During Muscular Activity / Microvascular Fluid and Solute Exchange in Skeletal Muscle / Skeletal Muscle Circulation in Aging and Disease States: Protective Effects of Exercise / References
Download or read book Sport Nutrition written by Asker E. Jeukendrup and published by Human Kinetics Publishers. This book was released on 2009-12-31 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of "Sport Nutrition: An Introduction to Energy Production and Performance" presents the principles, background, and rationale for current nutrition guidelines specifically for athletes. Using a physiological basis, this text provides an in-depth look at the science behind sport nutrition. Students will come away with a comprehensive understanding of nutrition as it relates to sport and the influence of nutrition on exercise performance, training, and recovery. The chapters and the material within each chapter are sequenced in a logical order that will help instructors deliver a better course and spend less time in preparing lectures and tutorials. Instructors will also enjoy the completely new ancillaries with this edition, including an online instructor guide, test package, PowerPoint presentation package, and image bank. This text contains updated and expanded information to keep students current on the latest findings in sport nutrition: - A new chapter on training adaptations, including effects of nutrition on overtraining - New information on weight management and body composition for athletes - New research on carbohydrate and new recommendations for carbohydrate intake during training - An expanded discussion on the role of protein in strength and endurance exercise training - The latest information on exercise, nutrition, and immune function The new content complements the strong foundational information that the authors provided in the previous edition, including fuel sources for muscle and exercise metabolism, energy requirements for various sports, and a complete grounding in the macronutrients (carbohydrate, fat, and protein) and the micronutrients (vitamins and minerals). With more than 200 illustrations, new highlight boxes, and tables and sidebars throughout the text, students will be able to more easily grasp the scientific concepts presented in this text. Each chapter also includes learning objectives, key terms, and key points to help readers retain the information. The text presents not only nutrition principles but also the exercise biochemistry involved and the energy needs of athletes. Readers will better understand how supplements may be used in an athlete's diet, and they will learn how to separate fact from fallacy regarding the claims of the numerous nutritional supplements available today. More than a simple prescription of recommendations, this second edition of" Sport Nutrition" features a unique presentation that facilitates readers' understanding of the science supporting the nutrition recommendations. As a result, students will be prepared for advanced study and future careers, and professionals will gain the knowledge and confidence to provide sound advice to athletes.
Download or read book Sports Endocrinology written by F. Lanfranco and published by Karger Medical and Scientific Publishers. This book was released on 2016-06-28 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an up-to-date, extensive overview of the effects of physical activity and training on endocrine function. It gives insights into a complex relationship by describing effects with respect to exercise performance, growth, development, and ageing. It includes discussions of the endocrine response depending on exercise mode, intensity, and duration as well as on gender, age, and fitness level. Additionally the book deals with the impact of environmental and psychological factors on endocrine level. A substantial part of Sports Endocrinology is devoted to the 'hot topic' of hormonal doping in sports. The properties of androgens, growth hormone, erythropoietin, and dietary supplements are highlighted. The use and abuse among professional and recreational athletes is discussed and specific methods of detection are presented and explained. All contributors are well-known experts in sports medicine and endocrinology, endocrine physiology, pharmacology, and doping detection, so this book is a must-read for every professional involved in the field.
Download or read book Cellular Physiology and Metabolism of Physical Exercise written by Livio Luzi and published by Springer Nature. This book was released on 2023-07-07 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition discusses classical aspects of cellular physiology and the metabolism of physical exercise, as well as novel topics like exercise in transplantation and exercise in beta-cell failure, which mark the frontiers of research in sport-related sciences and research. The team of authors together with the editor are world-renowned experts in the field of physiology and metabolism applied to sport sciences. In order to make the book answering also to current pandemic clinical issue, this second edition includes new chapters, specifically dealing with COVID-related issues. Exercise physiologists, biologists and physicians will benefit from this book. However, the comprehensive nature of the content makes this publication suitable also for university classes of graduate and undergraduate student.
Download or read book Investigating Diet and Exercise Modifications on Delta 6 Desaturase and Ghrelin Regulation of Skeletal Muscle and White Adipose Tissue Lipid Metabolism written by Barbora Hucik-Worndl and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Evidence supports a role for delta-6 desaturase (D6D) and ghrelin in regulating white adipose tissue (WAT) and skeletal muscle metabolism, particularly in the context of lifestyle modifications such as dietary fat consumption and exercise training. Changes in D6D activity, an enzyme involved in omega-3 polyunsaturated fatty acid (n-3 PUFA) metabolism, are associated with ¬¬¬altered whole-body glucose metabolism and increased risk of developing metabolic diseases such as Type 2 diabetes (T2D). In addition to signaling hunger and stimulating growth hormone (GH) release, ghrelin contributes to the control of WAT lipolysis. Studies have shown that circulating ghrelin levels change with high-fat diet (HFD) consumption and exercise. However, it is unknown how D6D and ghrelin regulate adipose and skeletal muscle metabolism in the context of different lifestyle modifications. In the first part of the thesis, reduced D6D activity partially protected Fads2+/- mice from high-fat diet (HFD)-induced impairments in glucose tolerance. We also investigated the impact of different n-3 PUFA using a Fads2-/- mice. Mice were fed either a flaxseed (contains alpha-linolenic acid) or menhaden (eicosapentaenoic and docosahexaenoic acid) oil diet. Flax-fed Fads2-/- mice had increased insulin sensitivity and decreased body weight compared to menhaden-fed Fads2-/- mice. However, neither of these studies showed changes in whole-body energy expenditure, skeletal muscle lipid species content and composition, or other protein markers of glucose or fatty acid uptake, storage or oxidation. To our knowledge, these novel studies are the first to investigate the effect of D6D activity on skeletal muscle glucose and lipid metabolism. These findings suggest that dietary fat consumption (regardless of quantity or composition) does not influence the effects of D6D activity at the level of skeletal muscle. The last part of this thesis investigated the role of ghrelin in modulating B-adrenergic-stimulated WAT lipolysis. Although the acylated isoform (AG) blunted WAT lipolysis in LFD-fed rats, 5 days and 6 weeks of HFD consumption both impaired ghrelin's anti-lipolytic effect, which was not restored with exercise training. This study showed that HFD-feeding impairs ghrelin's ability to regulate WAT lipolysis. Collectively, this thesis demonstrates that D6D and ghrelin regulation of peripheral tissue metabolism is dependent on dietary fat content and composition.
Download or read book Regulation of Coronary Blood Flow written by Michitoshi Inoue and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
Download or read book The Effects of Diet and Chronic Exercise on Skeletal Muscle Ghrelin Response written by Andrew Lovell and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Ghrelin is an orexigenic hormone that was initially believed to only play a role in appetite regulation. Recently ghrelin has been shown to stimulate fatty acid oxidation and preserve insulin response in muscle in conditions of elevated fatty acid availability. These effects are lost following chronic high-fat feeding in skeletal muscle. Whether ghrelin's peripheral effects are altered with exercise has not been examined. We found that ghrelin response was present in skeletal muscle following 5 days of high, or low-fat feeding, but lost following 6 weeks of a high-fat diet. Exercise was able recover ghrelin mediated increases in fatty acid oxidation and the preservation of insulin stimulated glucose uptake. The preservation of ghrelin response was accompanied by increases in CRF-2R content, the purported receptor for UnAG in skeletal muscle. These findings suggest that exercise is able to prevent the development of skeletal muscle ghrelin resistance in high-fat fed rats.
Download or read book The Biology of Exercise written by Michael J. Joyner and published by Perspectives Cshl. This book was released on 2017 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exercise training provokes widespread transformations in the human body, requiring coordinated changes in muscle composition, blood flow, neuronal and hormonal signaling, and metabolism. These changes enhance physical performance, improve mental health, and delay the onset of aging and disease. Understanding the molecular basis of these changes is therefore important for optimizing athletic ability and for developing drugs that elicit therapeutic effects. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines the biological basis of exercise from the molecular to the systemic levels. Contributors discuss how transcriptional regulation, cytokine and hormonal signaling, glucose metabolism, epigenetic modifications, microRNA profiles, and mitochondrial and ribosomal functions are altered in response to exercise training, leading to improved skeletal muscle, hippocampal, and cardiovascular function. Cross talk among the pathways underlying tissue-specific and systemic responses to exercise is also considered. The authors also discuss how the understanding of such molecular mechanisms may lead to the development of drugs that mitigate aging and disease. This volume will therefore serve as a vital reference for all involved in the fields of sports science and medicine, as well as anyone seeking to understand the molecular mechanisms by which exercise promotes whole-body health.
Download or read book Food Components to Enhance Performance written by Institute of Medicine and published by National Academies Press. This book was released on 1994-02-01 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: The physiological or psychological stresses that employees bring to their workplace affect not only their own performance but that of their co-workers and others. These stresses are often compounded by those of the job itself. Medical personnel, firefighters, police, and military personnel in combat settingsâ€"among othersâ€"experience highly unpredictable timing and types of stressors. This book reviews and comments on the performance-enhancing potential of specific food components. It reflects the views of military and non-military scientists from such fields as neuroscience, nutrition, physiology, various medical specialties, and performance psychology on the most up-to-date research available on physical and mental performance enhancement in stressful conditions. Although placed within the context of military tasks, the volume will have wide-reaching implications for individuals in any job setting.
Download or read book Nutrition and Skeletal Muscle written by Stéphane Walrand and published by Academic Press. This book was released on 2018-10-24 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrition and Skeletal Muscle provides coverage of the evidence of dietary components that have proven beneficial for bettering adverse changes in skeletal muscle from disuse and aging. Skeletal muscle is the largest tissue in the body, providing elements of contraction and locomotion and acting as an important contributor to whole body protein and amino metabolism, glucose disposal and lipid metabolism. However, muscle loss, atrophy or weakness can occur when there are metabolic imbalances, disuse or aging. This book addresses the topic by providing insight and research from international leaders, making it the go-to reference for those in skeletal muscle physiology. Provides an understanding of the crucial role of skeletal muscle in global metabolic homeostasis regulation Delivers the information needed to understand the utilization of crucial supplements for the preservation of skeletal muscle Presents insights on research from international leaders in the field
