Download or read book Systems Biology written by Bernhard Palsson and published by Cambridge University Press. This book was released on 2015-01-26 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive single-authored textbook on genome-scale models and the bottom-up approach to systems biology.

Download or read book Reconstructing Biology written by John Vandermeer and published by . This book was released on 1996-05-02 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rave reviews for Reconstructing Biology "It is just the sort of book I would have expected from John Vandermeer who, for his entire professional life, has been a leading voice in trying to make people understand the true nature of the forces that are both inside and outside of human beings, and the correct relationship between human beings and the rest of nature."—R. C. Lewontin Harvard University "For over a decade now we have been inundated by massive tomes on the nature of race by psychologists and sociologists poorly trained in genetics and biology. Now, at last, a preeminent biologist explains the true nature of race differences.... The combination of scientific clarity, political insight, and historical acumen makes this one of the most important books yet published on the subject of race and racism."—Barry Mehler Ferris State University "Given the frequency with which we meet simplistic claims today that social behaviors such as criminality, alcoholism, shyness, homosexuality, or infidelity are genetically determined...Reconstructing Biology should be required reading for all students in the social as well as natural sciences."—Garland E. Allen Washington University in St. Louis A biologist takes a probing look at some of the most important questions facing postmodern civilization In Reconstructing Biology, noted biologist and educator John Vandermeer explores the ways in which the science of biology has been and continues to be misinterpreted and misappropriated on behalf of some of the most pernicious doctrines and policies of the past 200 years. From the politics of genetics to the biology of IQ, Reconstructing Biology is must reading for anyone concerned about the role of science in the most important social and political issues of our time.

Download or read book Reconstructing Scientific Revolutions written by Paul Hoyningen-Huene and published by University of Chicago Press. This book was released on 1993-05-15 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scholars from disciplines as diverse as political science and art history have offered widely differing interpretations of Kuhn's ideas, appropriating his notions of paradigm shifts and revolutions to fit their own theories, however imperfectly. Destined to become the authoritative philosophical study of Kuhn's work. Bibliography.

Download or read book Systems Biology written by Bernhard Ø. Palsson and published by Cambridge University Press. This book was released on 2006-01-16 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome sequences are now available that enable us to determine the biological components that make up a cell or an organism. The discipline of systems biology examines how these components interact and form networks, and how the networks generate whole cell functions corresponding to observable phenotypes. This textbook, devoted to systems biology, describes how to model networks, how to determine their properties, and how to relate these to phenotypic functions. The prerequisites are some knowledge of linear algebra and biochemistry. Though the links between the mathematical ideas and biological processes are made clear, the book reflects the irreversible trend of increasing mathematical content in biology education. Therefore to assist both teacher and student, in an associated website Palsson provides problem sets, projects and Powerpoint slides, and keeps the presentation in the book concrete with illustrative material and experimental results.

Download or read book Reconstructing Evolution written by Olivier Gascuel and published by Oxford University Press. This book was released on 2007-06-28 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book arises from the Mathematics of Evolution & Phylogenetics meeting at the Mathematical Institute Henri Poincare, Paris, in June 2005 and is based on ... reports presented by keynote speakers"--Back cover.

Download or read book Reconstructing the Past written by Elliott Sober and published by MIT Press. This book was released on 1991-02-05 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reconstructing the Past seeks to clarify and help resolve the vexing methodological issues that arise when biologists try to answer such questions as whether human beings are more closely related to chimps than they are to gorillas. It explores the case for considering the philosophical idea of simplicity/parsimony as a useful principle for evaluating taxonomic theories of evolutionary relationships. For the past two decades, evolutionists have been vigorously debating the appropriate methods that should be used in systematics, the field that aims at reconstructing phylogenetic relationships among species. This debate over phylogenetic inference, Elliott Sober observes, raises broader questions of hypothesis testing and theory evaluation that run head on into long standing issues concerning simplicity/parsimony in the philosophy of science. Sober treats the problem of phylogenetic inference as a detailed case study in which the philosophical idea of simplicity/parsimony can be tested as a principle of theory evaluation. Bringing together philosophy and biology, as well as statistics, Sober builds a general framework for understanding the circumstances in which parsimony makes sense as a tool of phylogenetic inference. Along the way he provides a detailed critique of parsimony in the biological literature, exploring the strengths and limitations of both statistical and nonstatistical cladistic arguments.

Download or read book Reconstructing Science and Theology in Postmodernity written by Jacqui A. Stewart and published by Routledge. This book was released on 2018-02-06 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title was first published in 2000: The author examines and critiques Pannenberg's elaboration of hermeneutics and evaluates his use of the sciences against the background of modernity. The study does not present Pannenberg's theory in itself, rather, it is confined to a critical assessment of his engagement with the sciences.

Download or read book Scientists in the Classroom written by J. Rudolph and published by Springer. This book was released on 2002-05-02 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the 1950s, leading American scientists embarked on an unprecedented project to remake high school science education. Dissatisfaction with the 'soft' school curriculum of the time advocated by the professional education establishment, and concern over the growing technological sophistication of the Soviet Union, led government officials to encourage a handful of elite research scientists, fresh from their World War II successes, to revitalize the nations' science curricula. In Scientists in the Classroom , John L. Rudolph argues that the Cold War environment, long neglected in the history of education literature, is crucial to understanding both the reasons for the public acceptance of scientific authority in the field of education and the nature of the curriculum materials that were eventually produced. Drawing on a wealth of previously untapped resources from government and university archives, Rudolph focuses on the National Science Foundation-supported curriculum projects initiated in 1956. What the historical record reveals, according to Rudolph, is that these materials were designed not just to improve American science education, but to advance the professional interest of the American scientific community in the postwar period as well.

Download or read book Quantitative Biology written by Brian Munsky and published by MIT Press. This book was released on 2018-08-21 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the quantitative modeling of biological processes, presenting modeling approaches, methodology, practical algorithms, software tools, and examples of current research. The quantitative modeling of biological processes promises to expand biological research from a science of observation and discovery to one of rigorous prediction and quantitative analysis. The rapidly growing field of quantitative biology seeks to use biology's emerging technological and computational capabilities to model biological processes. This textbook offers an introduction to the theory, methods, and tools of quantitative biology. The book first introduces the foundations of biological modeling, focusing on some of the most widely used formalisms. It then presents essential methodology for model-guided analyses of biological data, covering such methods as network reconstruction, uncertainty quantification, and experimental design; practical algorithms and software packages for modeling biological systems; and specific examples of current quantitative biology research and related specialized methods. Most chapters offer problems, progressing from simple to complex, that test the reader's mastery of such key techniques as deterministic and stochastic simulations and data analysis. Many chapters include snippets of code that can be used to recreate analyses and generate figures related to the text. Examples are presented in the three popular computing languages: Matlab, R, and Python. A variety of online resources supplement the the text. The editors are long-time organizers of the Annual q-bio Summer School, which was founded in 2007. Through the school, the editors have helped to train more than 400 visiting students in Los Alamos, NM, Santa Fe, NM, San Diego, CA, Albuquerque, NM, and Fort Collins, CO. This book is inspired by the school's curricula, and most of the contributors have participated in the school as students, lecturers, or both. Contributors John H. Abel, Roberto Bertolusso, Daniela Besozzi, Michael L. Blinov, Clive G. Bowsher, Fiona A. Chandra, Paolo Cazzaniga, Bryan C. Daniels, Bernie J. Daigle, Jr., Maciej Dobrzynski, Jonathan P. Doye, Brian Drawert, Sean Fancer, Gareth W. Fearnley, Dirk Fey, Zachary Fox, Ramon Grima, Andreas Hellander, Stefan Hellander, David Hofmann, Damian Hernandez, William S. Hlavacek, Jianjun Huang, Tomasz Jetka, Dongya Jia, Mohit Kumar Jolly, Boris N. Kholodenko, Markek Kimmel, Michał Komorowski, Ganhui Lan, Heeseob Lee, Herbert Levine, Leslie M Loew, Jason G. Lomnitz, Ard A. Louis, Grant Lythe, Carmen Molina-París, Ion I. Moraru, Andrew Mugler, Brian Munsky, Joe Natale, Ilya Nemenman, Karol Nienałtowski, Marco S. Nobile, Maria Nowicka, Sarah Olson, Alan S. Perelson, Linda R. Petzold, Sreenivasan Ponnambalam, Arya Pourzanjani, Ruy M. Ribeiro, William Raymond, William Raymond, Herbert M. Sauro, Michael A. Savageau, Abhyudai Singh, James C. Schaff, Boris M. Slepchenko, Thomas R. Sokolowski, Petr Šulc, Andrea Tangherloni, Pieter Rein ten Wolde, Philipp Thomas, Karen Tkach Tuzman, Lev S. Tsimring, Dan Vasilescu, Margaritis Voliotis, Lisa Weber

Download or read book Reconstructing the Tree of Life written by Trevor R. Hodkinson and published by CRC Press. This book was released on 2006-12-26 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: To document the world's diversity of species and reconstruct the tree of life we need to undertake some simple but mountainous tasks. Most importantly, we need to tackle species rich groups. We need to collect, name, and classify them, and then position them on the tree of life. We need to do this systematically across all groups of organisms and b

Download or read book Eukaryotic Membranes and Cytoskeleton written by Gáspár Jékely and published by Springer. This book was released on 2010-10-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The presence/absence of gene families with central roles in endomembrane and cytoskeleton dynamics in a variety of eukaryotic taxa and an understanding of eukaryote phylogeny allow the cellular machineries present in the last common ancestor of eukaryotes to be accurately reconstructed. Such a reconstruction is fundamental in order to understand eukaryotic diversification, since this is the ancestral cell from which all diversity arose. This book discusses the evolutionary origin and diversification of eukaryotic endomembranes and cytoskeleton from a cell biological and comparative genomic perspective.

Download or read book Life s Splendid Drama written by Peter J. Bowler and published by University of Chicago Press. This book was released on 1996-11-15 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: As Bowler tracks major scientific debates over the emergence of the vertebrates, the origins of the main types of living animals, and the rise and extinction of groups such as the dinosaurs, his richly detailed accounts bring to light complex interactions among specialists in various fields of biology.

Download or read book Reconstructing Sustainability Science written by Thaddeus R. Miller and published by Routledge. This book was released on 2014-12-05 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growing urgency, complexity and "wickedness" of sustainability problems—from climate change and biodiversity loss to ecosystem degradation and persistent poverty and inequality—present fundamental challenges to scientific knowledge production and its use. While there is little doubt that science has a crucial role to play in our ability to pursue sustainability goals, critical questions remain as to how to most effectively organize research and connect it to actions that advance social and natural wellbeing. Drawing on interviews with leading sustainability scientists, this book examines how researchers in the emerging, interdisciplinary field of sustainability science are attempting to define sustainability, establish research agendas, and link the knowledge they produce to societal action. Pairing these insights with case studies of innovative sustainability research centres, the book reformulates the sustainability science research agenda and its relationship to decision-making and social action. It repositions the field as a "science of design" that aims to enrich public reasoning and deliberation while also working to generate social and technological innovations for a more sustainable future. This timely book gives students, researchers and practitioners a valuable and unique analysis of the emergence of sustainability science, and both the opportunities and barriers faced by scientific efforts to contribute to social action.

Download or read book Reconstructing Evolution written by Olivier Gascuel and published by OUP Oxford. This book was released on 2007-06-28 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evolution is a complex process, acting at multiple scales, from DNA sequences and proteins to populations of species. Understanding and reconstructing evolution is of major importance in numerous subfields of biology. For example, phylogenetics and sequence evolution is central to comparative genomics, attempts to decipher genomes, and molecular epidemiology. Phylogenetics is also the focal point of large-scale international biodiversity assessment initiatives such as the 'Tree of Life' project, which aims to build the evolutionary tree for all extant species. Since the pioneering work in phylogenetics in the 1960s, models have become increasingly sophisticated to account for the inherent complexity of evolution. They rely heavily on mathematics and aim at modelling and analyzing biological phenomena such as horizontal gene transfer, heterogeneity of mutation, and speciation and extinction processes. This book presents these recent models, their biological relevance, their mathematical basis, their properties, and the algorithms to infer them from data. A number of subfields from mathematics and computer science are involved: combinatorics, graph theory, stringology, probabilistic and Markov models, information theory, statistical inference, Monte Carlo methods, continuous and discrete algorithmics. This book arises from the Mathematics of Evolution & Phylogenetics meeting at the Mathematical Institute Henri Poincaré, Paris, in June 2005 and is based on the outstanding state-of-the-art reports presented by the conference speakers. Ten chapters - based around five themes - provide a detailed overview of key topics, from the underlying concepts to the latest results, some of which are at the forefront of current research.

Download or read book Ancestral Sequence Reconstruction written by David A Liberles and published by OUP Oxford. This book was released on 2007-05-31 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ancestral sequence reconstruction is a technique of growing importance in molecular evolutionary biology and comparative genomics. As a powerful tool for testing evolutionary and ecological hypotheses, as well as uncovering the link between sequence and molecular phenotype, there are potential applications in a range of fields. Ancestral Sequence Reconstruction starts with a historical overview of the field, before discussing the potential applications in drug discovery and the pharmaceutical industry. This is followed by a section on computational methodology, which provides a detailed discussion of the available methods for reconstructing ancestral sequences (including their advantages, disadvantages, and potential pitfalls). Purely computational applications of the technique are then covered, including whole proteome reconstruction. Further chapters provide a detailed discussion on taking computationally reconstructed sequences and synthesizing them in the laboratory. The book concludes with a description of the scientific questions where experimental ancestral sequence reconstruction has been utilized to provide insights and inform future research. This research level text provides a first synthesis of the theories, methodologies and applications associated with ancestral sequence recognition, while simultaneously addressing many of the hot topics in the field. It will be of interest and use to both graduate students and researchers in the fields of molecular biology, molecular evolution, and evolutionary bioinformatics.

Download or read book Reconstructing Obesity written by Megan B. McCullough and published by Berghahn Books. This book was released on 2013-10-01 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the crowded and busy arena of obesity and fat studies, there is a lack of attention to the lived experiences of people, how and why they eat what they do, and how people in cross-cultural settings understand risk, health, and bodies. This volume addresses the lacuna by drawing on ethnographic methods and analytical emic explorations in order to consider the impact of cultural difference, embodiment, and local knowledge on understanding obesity. It is through this reconstruction of how obesity and fatness are studied and understood that a new discussion will be introduced and a new set of analytical explorations about obesity research and the effectiveness of obesity interventions will be established.

Download or read book Three Dimensional Reconstruction in Biology written by P. N. Gaunt and published by . This book was released on 1978 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: