Download or read book RECOMB 2004 written by Dan Gusfield and published by Association for Computing Machinery (ACM). This book was released on 2004 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book RECOMB 2003 written by Webb Miller and published by . This book was released on 2003 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: We study haplotype reconstruction under the Mendelian law of inheritance and the minimum recombination principleon pedigree data. We prove that the problem of finding a mini-mum-recombinant haplotype configuration (MRHC) is in general NP-hard. This is the first complexity result concerning the problem to our knowledge. An iterative algorithm based on blocks of consecutive resolved marker loci (called block-extension) is proposed. It is very efficient and can be used for large pedigrees with a large number of markers, especially for those data sets requiring few recombinants (or recombination events). A polynomial-time exact algorithm for haplotype reconstruction without recombinants is also presented. This algorithm first identifies all the necessary constraints based on the Mendelian law and the zero recombinant assumption, and represents them using a system of linear equations over the cyclic group Z2. By using a simple method based on Gaussian elimination, we could obtain all possible feasible haplotype configurations. We have tested the block-extension algorithm on simulated data generated on three pedigree structures. The results show that the algorithm performs very well on both multi-allelic and biallelic data, especially when the number of recombinants is small.
Download or read book Recombinant DNA Technical Bulletin written by and published by . This book was released on 1981 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Recombinant DNA Technical Bulletin written by and published by . This book was released on 1984 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Calbiochem General Catalog written by and published by . This book was released on 2002 with total page 1232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Combinatorics of Genome Rearrangements written by Guillaume Fertin and published by MIT Press. This book was released on 2009 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of a rapidly expanding field of combinatorial optimization, mathematically oriented but offering biological explanations when required. From one cell to another, from one individual to another, and from one species to another, the content of DNA molecules is often similar. The organization of these molecules, however, differs dramatically, and the mutations that affect this organization are known as genome rearrangements. Combinatorial methods are used to reconstruct putative rearrangement scenarios in order to explain the evolutionary history of a set of species, often formalizing the evolutionary events that can explain the multiple combinations of observed genomes as combinatorial optimization problems. This book offers the first comprehensive survey of this rapidly expanding application of combinatorial optimization. It can be used as a reference for experienced researchers or as an introductory text for a broader audience. Genome rearrangement problems have proved so interesting from a combinatorial point of view that the field now belongs as much to mathematics as to biology. This book takes a mathematically oriented approach, but provides biological background when necessary. It presents a series of models, beginning with the simplest (which is progressively extended by dropping restrictions), each constructing a genome rearrangement problem. The book also discusses an important generalization of the basic problem known as the median problem, surveys attempts to reconstruct the relationships between genomes with phylogenetic trees, and offers a collection of summaries and appendixes with useful additional information.
Download or read book Current Organic Chemistry written by and published by . This book was released on 2006 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides in depth reviews on current progress in the fields of asymmetric synthesis, organometallic chemistry, bioorganic chemistry, heterocyclic chemistry, natural product chemistry, and analytical methods in organic chemistry. Each issue is edited by an appointed Executive Guest Editor.
Download or read book Viruses written by Edwin J. Atencio and published by Academic Press. This book was released on 2014-05-10 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nucleotide Sequences 1986/1987, Volume VI: Viruses presents data that reflect the information found in GenBank Release 44.0 of August 1986. This book provides information pertinent to the unique international collaboration between two leading nucleotide sequence data libraries, one based in Europe and one in the United States. Organized into one section, this volume begins with an overview of the sequences, some basic identifying information, and some of the biological annotations. This text then discusses the EMBL Nucleotide Sequence Data Library, an international center of fundamental research with its main focus in the fields of cell biology, molecular structures, instrumentation, and differentiation. This book discusses as well the GenBank database established in 1982 by the National Institute of General Medical Sciences (NIGMS) of the U.S National Institutes of Health (NIH). This book is a valuable resource for molecular biologists and other investigators collecting the large number of reported DNA and RNA sequences and making them available in computer-readable form.
Download or read book Research in Computational Molecular Biology written by Lenore J. Cowen and published by Springer. This book was released on 2019-04-15 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the proceedings of the 23rd Annual Conference on Research in Computational Molecular Biology, RECOMB 2019, held in Washington, DC, USA, in April 2019. The 17 extended and 20 short abstracts presented were carefully reviewed and selected from 175 submissions. The short abstracts are included in the back matter of the volume. The papers report on original research in all areas of computational molecular biology and bioinformatics.
Download or read book Cancer Research written by and published by . This book was released on 1990 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genetics and the Law III written by Aubrey Milunsky and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: It was the best of times, it was the worst of times, it was the age of wisdom, it was the age of foolishness, it was the epoch of belief, it was the epoch of incredulity, ... it was the spring of hope, it was the winter of despair. . . . -Charles Dickens, A Tale of Two Cities Dickens, of course, did not have the contemporary dilemmas of modern genetics in mind. Indeed, we need to remind ourselves how short the history of modern genetics really is. Recognition that genetic traits are carried by deoxyribonucleic acid (DNA) occurred only about 40 years ago. Knowledge of the three-dimensional structure of DNA is only about 30 years old. The correct number of human chromosomes was not deter mined until the mid-1950s, and Down syndrome was recognized only in 1959. It was not until in 1968 that the exact location of a gene was determined on an autosomal chromo some, and the study of genes, rather than their protein products, has been possible for barely a decade.
Download or read book Science Policy Implications of DNA Recombinant Molecule Research written by United States. Congress. House. Committee on Science and Technology. Subcommittee on Science, Research, and Technology and published by . This book was released on 1977 with total page 1322 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Recombinant DNA Research written by and published by . This book was released on 1981 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Recombinant DNA Regulation Act 1977 written by United States. Congress. Senate. Committee on Human Resources. Subcommittee on Health and Scientific Research and published by . This book was released on 1977 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Final Environmental Impact Statement on NIH Guidelines for Research Involving Recombinant DNA Molecules written by National Institutes of Health (U.S.) and published by . This book was released on 1977 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Radiation Detectors for Medical Imaging written by Jan S. Iwanczyk and published by CRC Press. This book was released on 2015-10-16 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiation Detectors for Medical Imaging discusses the current state of the art and future prospects of photon-counting detectors for medical imaging applications. Featuring contributions from leading experts and pioneers in their respective fields, this book:Describes x-ray spectral imaging detectors based on cadmium zinc telluride (CdZnTe) and cad
Download or read book Structural RNA Synthetic and Unannotated Sequences written by Edwin J. Atencio and published by Elsevier. This book was released on 2014-05-10 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nucleotide Sequences 1986/1987, Volume VII: Structural RNA, Synthetic, and Unannotated Sequences presents data that reflect the information found in GenBank Release 44.0 of August 1986. This book provides information pertinent to the unique international collaboration between two leading nucleotide sequence data libraries, one based in Europe and one in the United States. Organized into three sections, this volume begins with an overview of the sequences, some basic identifying information, and some of the biological annotations. This text then discusses the EMBL Nucleotide Sequence Data Library, an international center of fundamental research with its main focus in the fields of cell biology, molecular structures, instrumentation, and differentiation. This book discusses as well the GenBank database established in 1982 by the National Institute of General Medical Sciences (NIGMS) of the U.S National Institutes of Health (NIH). This book is a valuable resource for molecular biologists and other investigators collecting the large number of reported DNA and RNA sequences and making them available in computer-readable form.
