Download or read book Receptor Autoradiography written by Dr. John Wharton and published by . This book was released on 1993 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Receptor autoradiography is an invaluable technique that is widely used to localize and characterize peptide and neurotransmitter binding sites. Its extensive use reflects the utility of the technique and the important advantages it offers over conventional biochemical procedures. This instructive work makes receptor autoradiography more accessible by giving a detailed account of the methodology and its application in the analysis of receptors in the brain and peripheral organs. These examples are not exhaustive but illustrate the versatility of the technique as well as its potential pitfalls. The book provides an introduction to the receptor concept and gives detailed information on the theory and procedures involved in the autoradiographic localization and quantification of radiolabelled ligand binding sites. This volume will be an essential tool for neuroscientists, pharmacologists, histochemists, neuropathologists, researchers in the pharmaceutical industry, and students of the biological sciences.

Download or read book Receptor Localization written by Frances M. Leslie and published by . This book was released on 1988 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Receptor Localization written by Marjorie Ariano and published by John Wiley & Sons. This book was released on 1998-07-16 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The detection of neurotransmitter receptor locations and distribution densities within the central nervous system and peripheral tissues is receiving intense attention within the neuroscience research community. Neurotransmitter receptors, which receive the chemical signals sent from one neuron to another, are critical links in a highly complex information-processing chain. Pinpointing receptor sites and systems is crucial for understanding neurological function as well as dysfunction. It is also essential for understanding how receptors process information when impacted by such substances as heroin or nicotine, or when affected by neurodegenerative disease. Receptor Localization: Laboratory Methods and Procedures is the first user-friendly guide to the latest techniques and approaches being employed to examine the localization of neurotransmitter receptors in the central nervous system and peripheral tissues. It covers detection methods that are applicable to a wide variety of receptor systems, ranging from genes and ligands to in vito receptors in individuals; and to numerous receptor subtypes, such as nicotine, muscarine, tackykinins, dopamine, adenosine, and GABA. The standard laboratory "recipes" or "tricks" employed in these detection methods are fully discussed, as are the advantages and limitations of each procedure. With contributions from leading experts and extensively illustrated, this book: * Discusses receptor ligand binding methods using irreversible and reversible compounds * Presents antireceptor antisera technology using synthetic peptides and fusion proteins at both the cellular and subcellular resolution levels * Examines molecular assessments of receptors * Describes in situ hybridization, reverse transcriptase-PCR, and fluorescent in situ transcription * Covers new visualization paradigms * Includes physiological analysis of receptor function, cellular detection in the brain slice, and cultured neurons * Discusses the use of PET and SPECT to assess in vivo receptor distributions in animals and humans Receptor Localization: Laboratory Methods and Procedures is an invaluable guide for researchers in the related fields of neurology, biochemistry, and pharmacology. Its lucid descriptions of new detection methods, inclusion of experimental examples, and emphasis on how these experimental approaches are applicable to particular research areas will appeal to both the experienced researcher and novice investigator.

Download or read book Quantitative Receptor Autoradiography written by Carl A. Boast and published by . This book was released on 1986 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Receptors in the Human Nervous System written by F. A. O. Mendelsohn and published by Academic Press. This book was released on 2013-10-22 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Receptors in the Human Nervous System is a synthesis of the results of receptor mapping by leaders in the field. In addition to a comprehensive discussion of the distribution and possible interactions of the receptors of different neuroactive substances, this book also contains an abundance of pictorial representations of receptor distributions. High-quality photographs of one receptor are often juxtaposed with photographs of the distribution of a different receptor or receptor subtype for the consideration of possible interactions between different systems. The book surveys the distribution of receptor subtypes for the classical monoamine transmitters (acetylcholine, adrenaline, noradrenaline and serotonin) as well as the distribution of receptors for the excitatory and inhibitory amino acids, (glutamate, GABA and benzodiazepines) as well as the opioid peptides, angiotensen and other neuropeptides. The distribution of multiple types of serotonin receptors is given in detail, and the codistribution of receptors in the cortex is discussed. The book is directed toward researchers in the field of chemical neuroanatomy, as well as pharmacologists, neurophysiologists, and neuroscientists.

Download or read book Drug Localization in Tissues and Cells written by Walter E. Stumpf and published by Iddc Press. This book was released on 2003-01-01 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Visualization of Receptors In Situ written by Emmanuel Moyse and published by CRC Press. This book was released on 2000-11-30 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioligand binding in situ is the most sensitive method for detecting available receptors; the success and reliability of this approach are determined by a number of technical requirements and constraints. Based on the authors' fifteen years of experience in the field, Visualization of Receptors In Situ: Applications of Radioligand Binding explici

Download or read book Quantitative Receptor Autoradiography in Opioid Peptide and Receptor Knockout Mice written by Sian Clarke and published by . This book was released on 2001 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Receptor Binding Techniques written by Mary Keen and published by Springer Science & Business Media. This book was released on 1999 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This cutting-edge collection of step-by-step experimental protocols demonstrates

Download or read book Neuroanatomical Tract Tracing Methods 2 written by Laszlo Zaborszky and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition presents readers with the latest information on neuroscience. This book explores the advances in molecular techniques, genomics and proteomics and the progress in fluorescence.

Download or read book Quantitative Receptor Autoradiography in Mu and Kappa opioid Knockout Mice written by Susan J. Slowe and published by . This book was released on 1999 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Whole body Autoradiography written by C. G. Curtis and published by . This book was released on 1981 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Quantitative Receptor Autoradiography written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Quantitative Receptor Autoradiography in Opoid Peptide and Receptor Knockout Mice written by S. Clarke and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Autoradiography and correlative imaging written by Walter E. Stumpf and published by Academic Pr. This book was released on 1995 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autoradiography and Correlative Imaging is an up-to-date, comprehensive text on using radioactivity to localize molecules in cells, tissues, and whole bodies. It provides historical discussions as well as useful protocols all in one convenient volume. Key Features * Autoradiography applications and techniques * Digital image processing * Uses of autoradiography in molecular biology and neurobiology * Correlative imaging in vivo receptor studies in metabolism and drug delivery

Download or read book Quantitative Receptors Autoradiography written by C. Boast and published by Wiley-Liss. This book was released on 1986-01-01 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Autoradiography written by H. A. Fischer and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-05-18 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Autoradiography".