Download or read book Scientific Frontiers in Developmental Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2000-12-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Recent Advances in Developmental Biology written by Ambika P. Diwan and published by . This book was released on 1995 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Animal Metamorphosis written by and published by Academic Press. This book was released on 2013-01-17 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Current Topics in Developmental Biology covers recent progresses in our understanding of animal metamorphosis. Over a dozen of leading experts reviews studies ranging from morphological, molecular to genetic analyses of metamorphosis in a broad spectrum of animals, including insects, fish. Topics include molecular evolution in metamorphosis, the synthesis and function of hormones in regulating metamorphic timing and rate, regulation and function of nuclear hormone receptors, neuroendocrine control of metamorphosis, tissue specific metamorphic events such as autophagy and stem cell development, and applications of genome-wide analysis technologies for studying metamorphosis. First comprehensive review of the metamorphosis in diverse animal species by leading experts in the field Covers a broad range of subjects: from morphological changes, molecular and genetic studies, to cutting-edge technologies for metamorphic studies; from systematic changes to tissue specific events, such as autophagy and stem cell development, which are areas of enormous interest in contemporary biomedical research Serves as a reference book for undergraduate and graduate students in fields across biology and biomedicine
Download or read book Recent Advances in Developmental Biology written by Ambika P. Diwan and published by . This book was released on 1995 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Development of Animal Form written by Alessandro Minelli and published by Cambridge University Press. This book was released on 2003-03-03 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contemporary research in the field of evolutionary developmental biology, or 'evo-devo', has to date been predominantly devoted to interpreting basic features of animal architecture in molecular genetics terms. Considerably less time has been spent on the exploitation of the wealth of facts and concepts available from traditional disciplines, such as comparative morphology, even though these traditional approaches can continue to offer a fresh insight into evolutionary developmental questions. The Development of Animal Form aims to integrate traditional morphological and contemporary molecular genetic approaches and to deal with post-embryonic development as well. This approach leads to unconventional views on the basic features of animal organization, such as body axes, symmetry, segments, body regions, appendages and related concepts. This book will be of particular interest to graduate students and researchers in evolutionary and developmental biology, as well as to those in related areas of cell biology, genetics and zoology.
Download or read book Evolutionary Developmental Biology written by Brian K. Hall and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although evolutionary developmental biology is a new field, its origins lie in the last century; the search for connections between embryonic development (ontogeny) and evolutionary change (phylogeny) has been a long one. Evolutionary developmental biology is however more than just a fusion of the fields of developmental and evolutionary biology. It forges a unification of genomic, developmental, organismal, population and natural selection approaches to evolutionary change. It is concerned with how developmental processes evolve; how evolution produces novel structures, functions and behaviours; and how development, evolution and ecology are integrated to bring about and stabilize evolutionary change. The previous edition of this title, published in 1992, defined the terms and laid out the field for evolutionary developmental biology. This field is now one of the most active and fast growing within biology and this is reflected in this second edition, which is more than twice the length of the original and brought completely up to date. There are new chapters on major transitions in animal evolution, expanded coverage of comparative embryonic development and the inclusion of recent advances in genetics and molecular biology. The book is divided into eight parts which: place evolutionary developmental biology in the historical context of the search for relationships between development and evolution; detail the historical background leading to evolutionary embryology; explore embryos in development and embryos in evolution; discuss the relationship between embryos, evolution, environment and ecology; discuss the dilemma for homology of the fact that development evolves; deal with the importance of understanding how embryos measure time and place both through development and evolutionarily through heterochrony and heterotrophy; and set out the principles and processes that underlie evolutionary developmental biology. With over one hundred illustrations and photographs, extensive cross-referencing between chapters and boxes for ancillary material, this latest edition will be of immense interest to graduate and advanced undergraduate students in cell, developmental and molecular biology, and in zoology, evolution, ecology and entomology; in fact anyone with an interest in this new and increasingly important and interdisciplinary field which unifies biology.
Download or read book Molecular Principles of Animal Development written by Alfonso Martinez Arias and published by Oxford University Press, USA. This book was released on 2002 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: An advanced undergraduate textbook focusing on the molecules and mechanisms which underlie the developmental process. In recent years, the genetic and molecular mechanisms underlying cellular behaviour have begun to be elucidated. Taking advantage of this new knowledge, Martinez Arias and Stewart here present developmental biology from a new standpoint: one in which the molecules and the genes that encode them, rather than the organisms, take centre stage. This is a compellingmodern way of looking at developmental biology. Starting with the genetic programs that underlie development and working up allows a better understanding of the logic of development. TEACHING AIDS Online Resource Centre: www.oup.com/uk/best.textbooks/biochemistry/martinez/ Includes sample chapter, and all illustrations available free to download
Download or read book Essays on Developmental Biology Part B written by Paul Wassarman and published by Academic Press. This book was released on 2016-03-10 with total page 916 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2016 Current Topics in Developmental Biology (CTDB) will celebrate its 50th or “golden anniversary. To commemorate the founding of CTDB by Aron Moscona (1921-2009) and Alberto Monroy (1913-1986) in 1966, a two-volume set of CTDB (volumes 116 and 117), entitled Essays on Development, will be published by Academic Press/Elsevier in early 2016. The volumes are edited by Paul M. Wassarman, series editor of CTDB, and include contributions from dozens of outstanding developmental biologists from around the world. Overall, the essays provide critical reviews and discussion of developmental processes for a variety of model organisms. Many essays relate the history of a particular area of research, others personal experiences in research, and some are quite philosophical. Essays on Development provides a window onto the rich landscape of contemporary research in developmental biology and should be useful to both students and investigators for years to come. Covers the area of developmental processes for a variety of model organisms International board of authors Part of two 50th Anniversary volumes proving a comprehensive set of reviews edited by Serial Editor Paul M. Wassarman
Download or read book Development and Reproduction in Humans and Animal Model Species written by Werner A. Mueller and published by Springer. This book was released on 2015-01-03 with total page 723 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes human development including sexual reproduction and stem cell research with the development of model organisms that are accessible to genetic and experimental analysis in readily understandable texts and 315 multi-colored graphics. The introductory account of model organisms selected from the entire animal kingdom presents general principles, which are then outlined in subsequent chapters devoted to, for example, sexual development; genes controlling development and their contemporary molecular-analysis methods; production of clones and transgenic animals; development of the nervous and circulatory systems; regenerative medicine and ageing. Finally the evolution of developmental toolkits and novelties is discussed including the genetic basis of the enlargement of the human forebrain. Separate boxes are devoted to controversial questions such as the benefits and problems of prenatal diagnostics or the construction of ancient body plans.
Download or read book Advances in Developmental Biology written by Paul Wassarman and published by Elsevier. This book was released on 1996-06-25 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 4 of Advances in Developmental Biology and Biochemistry consists of five chapters that review specific aspects of fly and mammalian development. In Chapter 1, Y. Mishina and R. Behringer discuss various aspects of Müllerian-inhibiting substance (MIS) in mammals, from a brief history of its discovery to recent studies of the MIS gene in transgenic and knock-out animals. In Chapter 2, C. Rushlow and S. Roth discuss the role of the dpp-group genes in dorsoventral patterning of the Drosophila embryo. In Chapter 3, M. Yip and H. Lipshitz discuss the terminal (asegmental termini) gene hierarchy of Drosophila and the genetic control of tissue specification and morphogenesis. In Chapter 4, R. Bachvarova discusses induction of mesoderm and the origin of anterior-posterior polarity in the mouse embryo, using the frog embryo as a paradigm. In Chapter 5, P. Vogt discusses human Y chromosome function in male germ cell development.
Download or read book Maternal Control of Development in Vertebrates written by Florence Louise Marlow and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eggs of all animals contain mRNAs and proteins that are supplied to or deposited in the egg as it develops during oogenesis. These maternal gene products regulate all aspects of oocyte development, and an embryo fully relies on these maternal gene products for all aspects of its early development, including fertilization, transitions between meiotic and mitotic cell cycles, and activation of its own genome. Given the diverse processes required to produce a developmentally competent egg and embryo, it is not surprising that maternal gene products are not only essential for normal embryonic development but also for fertility. This review provides an overview of fundamental aspects of oocyte and early embryonic development and the interference and genetic approaches that have provided access to maternally regulated aspects of vertebrate development. Some of the pathways and molecules highlighted in this review, in particular, Bmps, Wnts, small GTPases, cytoskeletal components, and cell cycle regulators, are well known and are essential regulators of multiple aspects of animal development, including oogenesis, early embryogenesis, organogenesis, and reproductive fitness of the adult animal. Specific examples of developmental processes under maternal control and the essential proteins will be explored in each chapter, and where known conserved aspects or divergent roles for these maternal regulators of early vertebrate development will be discussed throughout this review. Table of Contents: Introduction / Oogenesis: From Germline Stem Cells to Germline Cysts / Oocyte Polarity and the Embryonic Axes: The Balbiani Body, an Ancient Oocyte Asymmetry / Preparing Developmentally Competent Eggs / Egg Activation / Blocking Polyspermy / Cleavage/ Mitosis: Going Multicellular / Maternal-Zygotic Transition / Reprogramming: Epigenetic Modifications and Zygotic Genome Activation / Dorsal-Ventral Axis Formation before Zygotic Genome Activation in Zebrafish and Frogs / Maternal TGF-β and the Dorsal-Ventral Embryonic Axis / Maternal Control After Zygotic Genome Activation / Compensation by Stable Maternal Proteins / Maternal Contributions to Germline Establishment or Maintenance / Perspective / Acknowledgments / References
Download or read book Essential Developmental Biology written by Jonathan M. W. Slack and published by John Wiley & Sons. This book was released on 2021-12-01 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Developmental Biology ist eine umfassende und reich illustrierte Einführung in sämtliche Aspekte der Entwicklungsbiologie. Die 3. Auflage dieses beliebten und zugänglichen Lehrbuchs wurde erweitert und aktualisiert. Die begleitende Website bietet darüber hinaus Lehr- und Lernmaterialien für Studenten und Dozenten, animierte Entwicklungsprozesse, eine Fotogalerie ausgewählter Modellorganismen und sämtliche Abbildungen usw. der Printversion zum Herunterladen. Dieses evidenzbasierte Lehrbuch liefert durchgängig Belege für zentrale Schlussfolgerungen und ist ein Muss sowohl für Einführungs- als auch Aufbaukurse der Entwicklungsbiologie.
Download or read book Genetic Analysis of Animal Development written by Adam S. Wilkins and published by Wiley-Liss. This book was released on 1993 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated and expanded to address the latest trends in developmental genetics by examining the developmental biology of three model animal systems with a vast range of complexity and phylogenetic distance--the nematode, fruitfly and mouse. This edition places greater emphasis on molecular approaches to pattern and development formation; introduces key issues and questions involving developmental biology; explores the final stages of patterning.
Download or read book Developmental Biology written by Werner Müller and published by Springer Science & Business Media. This book was released on 1996-12-13 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: No field of contemporary biomedical science has been more revolutionized by the techniques of molecular biology than developmental biology. This is an outstanding concise introduction to developmental biology that takes a contemporary approach to describing the complex process that transforms an egg into an adult organism. The book features exceptionally clear two-color illustrations, and is designed for use in both undergraduate and graduate level courses. The book is especially noteworthy for its treatment of development in model organisms, whose contributions to developmental biology were recognized in the 1995 Nobel Prize for physiology and medicine.
Download or read book Recent Advances in Developmental Biology of Animals written by Suresh C. Goel and published by . This book was released on 1985 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Animal Genomics written by Sukanta Mondal and published by Academic Press. This book was released on 2020-11-25 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Animal Genomics provides an outstanding collection of integrated strategies involving traditional and modern - omics (structural, functional, comparative and epigenomics) approaches and genomics-assisted breeding methods which animal biotechnologists can utilize to dissect and decode the molecular and gene regulatory networks involved in the complex quantitative yield and stress tolerance traits in livestock. Written by international experts on animal genomics, this book explores the recent advances in high-throughput, next-generation whole genome and transcriptome sequencing, array-based genotyping, and modern bioinformatics approaches which have enabled to produce huge genomic and transcriptomic resources globally on a genome-wide scale. This book is an important resource for researchers, students, educators and professionals in agriculture, veterinary and biotechnology sciences that enables them to solve problems regarding sustainable development with the help of current innovative biotechnologies. Integrates basic and advanced concepts of animal biotechnology and presents future developments Describes current high-throughput next-generation whole genome and transcriptome sequencing, array-based genotyping, and modern bioinformatics approaches for sustainable livestock production Illustrates integrated strategies to dissect and decode the molecular and gene regulatory networks involved in complex quantitative yield and stress tolerance traits in livestock Ensures readers will gain a strong grasp of biotechnology for sustainable livestock production with its well-illustrated discussion
