Download or read book Real Time Analysis of Biomolecular Interactions written by K. Nagata and published by Springer Science & Business Media. This book was released on 2013-12-11 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: The metabolism of all living organisms consists of elaborate and complex interactions among numbers of biomolecules, including protein-protein interactions. BIACORE is a new device that uses surface plasmon resonance for kinetic analysis of molecular interactions and automates whole analytical processes. The number of users of BIACORE is increasing worldwide, but until now nothing had been published in English to explain the principles of this new methodology and the kinds of applications it makes available. This updated and revised version of the Japanese original explains the underlying principles of BIACORE, providing concrete examples that utilize the methodology for analysis in areas ranging from basic to applied sciences. With its generous use of illustrations, this book is a valuable source of information for all users of BIACORE.
Download or read book Real time Analysis of Biomolecular Interactions written by Kazuhiro Nagata and published by Springer Verlag Tokyo. This book was released on 2000 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biomolecular Interactions Part B written by and published by Academic Press. This book was released on 2022-05-25 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomolecular Interactions: Part A, Volume 169, the latest release in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Emerging Mechanisms of Targeted Protein Degradation by Molecular Glues, Design and use of programmable DNA Hydrogels, Oligomerization of membrane receptors: Approaches to measure in live cells, Interactions of alpha-synuclein with biomolecules, Gel-electrophoresis based method for biomolecular interaction, Recombinant centrosome expression in bacterial system, Reconstituting CCL5-CCR5 complex for structural and mechanistic analysis, Protein engineering and design in ion channel receptors, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Cell Biology series Updated release includes the latest information on biomolecular interactions instead of protein-protein interactions
Download or read book Real time Biomolecular Interaction Analysis written by John G. Quinn and published by . This book was released on 1999 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cellular and Biomolecular Recognition written by Raz Jelinek and published by John Wiley & Sons. This book was released on 2009-07-10 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: With its exploration of the scientific and technological characteristics of systems exploiting molecular recognition between synthetic materials, such as polymers and nanoparticles, and biological entities, this is a truly multidisciplinary book bridging chemistry, life sciences, pharmacology and medicine. The authors introduce innovative biomimetic chemical assemblies which constitute platforms for recruitment of cellular components or biological molecules, while also focusing on physical, chemical, and biological aspects of biomolecular recognition. The diverse applications covered include biosensors, cell adhesion, synthetic receptors, cell patterning, bioactive nanoparticles, and drug design.
Download or read book The Proteomics Protocols Handbook written by John M. Walker and published by Springer Science & Business Media. This book was released on 2007-10-09 with total page 969 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hands-on researchers describe in step-by-step detail 73 proven laboratory methods and bioinformatics tools essential for analysis of the proteome. These cutting-edge techniques address such important tasks as sample preparation, 2D-PAGE, gel staining, mass spectrometry, and post-translational modification. There are also readily reproducible methods for protein expression profiling, identifying protein-protein interactions, and protein chip technology, as well as a range of newly developed methodologies for determining the structure and function of a protein. The bioinformatics tools include those for analyzing 2D-GEL patterns, protein modeling, and protein identification. All laboratory-based protocols follow the successful Methods in Molecular BiologyTM series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Download or read book Advances in Protein Molecular and Structural Biology Methods written by Timir Tripathi and published by Academic Press. This book was released on 2022-01-14 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also covers methods applied to intrinsically disordered proteins (IDPs)followed by chapters on protein interaction networks, protein function, and protein design and engineering. It provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application. Presents a thorough overview of the latest and emerging methods and technologies for protein study Explores biophysical techniques, including nuclear magnetic resonance, X-ray crystallography, and cryo-electron microscopy Includes computational and machine learning methods Features a section dedicated to tools and techniques specific to studying intrinsically disordered proteins
Download or read book Proteomics in Drug Research written by Michael Hamacher and published by John Wiley & Sons. This book was released on 2006-03-31 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: From skillful handling of the wide range of technologies to successful applications in drug discovery -- this handbook has all the information professional proteomics users need. Edited by experts working at one of the hot spots in European proteomic research, the numerous contributions by experts from the pharmaceutical industry and public proteomics consortia to provide the necessary perspective on current trends and developments in this exciting field. Following an introductory chapter, the book moves on to proteomic technologies, such as protein biochips, protein-protein interactions, and proteome analysis in situ. The section on applications includes bioinformatics, Alzheimer's disease, neuroproteomics, plasma and T-cell proteomics, differential phosphoproteome analysis and biomarkers, as well as pharmacogenomics. Invaluable reading for medicinal and pharmaceutical chemists, gene technologists, molecular biologists, and those working in the pharmaceutical industry.
Download or read book Handbook of Surface Plasmon Resonance written by Richard B M Schasfoort and published by Royal Society of Chemistry. This book was released on 2008-03-10 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface plasmon resonance (SPR) plays a dominant role in real-time interaction sensing of biomolecular binding events. This book focuses on a total system description including optics, fluidics and sensor surfaces. It covers all commercial SPR systems in the market. It is the first of its kind and fills a gap in the technical literature as no other handbook on SPR is currently available. The final chapter discussed new trends and a vision is given for future developments and needs of the SPR market. This excellent handbook provides comprehensive information with easy to use, stand-alone chapters and will be of great use to anyone one working with or affiliated to the technology.
Download or read book The Third World Congress on Biosensors Abstracts written by Abstracts and published by Elsevier. This book was released on 2014-06-28 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Third World Congress on Biosensors Abstracts
Download or read book Biomolecular Kinetics written by Clive R. Bagshaw and published by CRC Press. This book was released on 2017-10-04 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: "a gem of a textbook which manages to produce a genuinely fresh, concise yet comprehensive guide" –Mark Leake, University of York "destined to become a standard reference.... Not just a ‘how to’ handbook but also an accessible primer in the essentials of kinetic theory and practice." –Michael Geeves, University of Kent "covers the entire spectrum of approaches, from the traditional steady state methods to a thorough account of transient kinetics and rapid reaction techniques, and then on to the new single molecule techniques" –Stephen Halford, University of Bristol This illustrated treatment explains the methods used for measuring how much a reaction gets speeded up, as well as the framework for solving problems such as ligand binding and macromolecular folding, using the step-by-step approach of numerical integration. It is a thoroughly modern text, reflecting the recent ability to observe reactions at the single-molecule level, as well as advances in microfluidics which have given rise to femtoscale studies. Kinetics is more important now than ever, and this book is a vibrant and approachable entry for anyone who wants to understand mechanism using transient or single molecule kinetics without getting bogged down in advanced mathematics. Clive R. Bagshaw is Emeritus Professor at the University of Leicester, U.K., and Research Associate at the University of California at Santa Cruz, U.S.A.
Download or read book Sensors for Chemical and Biological Applications written by Manoj Kumar Ram and published by CRC Press. This book was released on 2018-10-03 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, sensor research has undergone a quiet revolution that will have a significant impact on a broad range of applications in areas such as health care, the environment, energy, food safety, national security, and manufacturing. Sensors for Chemical and Biological Applications discusses in detail the potential of chemical and biological sensors and examines how they are meeting the challenges of chem-bio terrorism by monitoring through enhanced specificity, fast response times, and the ability to determine multiple hazardous substances. Exploring the nanotechnology approach, and carrying this theme throughout the book, the chapters cover the sensing principles for, chemical, electrical, chromatographic, magnetic, biological, fluidic, optical, and ultrasonic and mass sensing systems. They address issues associated with cost, synthesis, and testing of new low cost materials with high sensitivity, selectivity, robustness, and speed for defined sensor applications. The book extensively discusses the detailed analysis of future impact of chemical and biological sensors in day-to-day life. Successful development of improved chemical sensor and biosensor systems and manufacturing procedures will not only increase the breadth and depth of the sensor industry, but will spill over into the design and manufacture of other types of sensors and devices that use nanofabrication and microfabrication techniques. This reference not only supplies versatile, hands-on tools useful in a broad array of disciplines, but also lays the interdisciplinary groundwork required for the achievement of sentient processing.
Download or read book Electrospray and MALDI Mass Spectrometry written by Richard B. Cole and published by John Wiley & Sons. This book was released on 2011-09-26 with total page 900 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover how advances in mass spectrometry are fueling new discoveries across a broad range of research areas Electrospray and MALDI Mass Spectrometry brings both veteran practitioners and beginning scientists up to date with the most recent trends and findings in electrospray ionization and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. In particular, this Second Edition highlights how advances in electrospray and MALDI mass spectrometry are supporting important discoveries in new and emerging fields such as proteomics and metabolomics as well as in traditional areas of chemistry and physics research. Electrospray AND MALDI Mass Spectrometry, SECOND EDITION is divided into five parts: Part A, Fundamentals of ES, explains the fundamental phenomena underlying the electrospray process, including selectivity in ionization and inherent electrochemistry, and concludes with a chapter offering a comparative inventory of source hardware Part B, Fundamentals of MALDI, confronts ionization mechanisms, instrument development, and matrix selection, and includes a final chapter that explores the special application of MALDI to obtain two-dimensional images of spatial distributions of compounds on surfaces Part C, ES and MALDI Coupling to Mass Spectrometry Instrumentation, examines the coupling of these ionization techniques to various mass analyzers, including quadrupole ion trap, time-of-flight, Fourier transform ion cyclotron resonance, and ion mobility mass spectrometers Part D, Practical Aspects of ES and MALDI, investigates analytical issues including quantification, charge-state distributions, noncovalent interactions in solution that are preserved as gas-phase ions, and various means of ion excitation in preparation for tandem mass spectrometry, and offers a guide to the interpretation of even-electron mass spectra Part E, Biological Applications of ES and MALDI, examines the role of mass spectrometry in such areas as peptide and protein characterization, carbohydrate analysis, lipid analysis, and drug discovery Written by a team of leading experts, the book not only provides a critical review of the literature, but also presents key concepts in tutorial fashion to help readers take full advantage of the latest technological breakthroughs and applications. As a result, Electrospray and MALDI Mass Spectrometry will help researchers fully leverage the power of electrospray and MALDI mass spectrometry. The judicious compartmentalization of chapters, and the pedagogic presentation style throughout, render the book highly suitable for use as a text for graduate-level courses in advanced mass spectrometry.
Download or read book Biomolecular Interactions Part A written by and published by Academic Press. This book was released on 2021-10-29 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomolecular Interactions: Part A, Volume 166, the latest release in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics in cell biology. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Cell Biology series Updated release includes the latest information on biomolecular interactions instead of protein-protein interactions
Download or read book Analyzing Biomolecular Interactions by Mass Spectrometry written by Jeroen Kool and published by John Wiley & Sons. This book was released on 2015-02-09 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section also emphasizes the use of ion mobility MS, capture-compound approaches, chemical proteomics and interactomics. The third and final part discusses other important technologies frequently employed in interaction studies, such as biosensors and microarrays. For pharmaceutical, analytical, protein, environmental and biochemists, as well as those working in pharmaceutical and analytical laboratories.
Download or read book Applications of Nanomaterials in Agriculture Food Science and Medicine written by Bhat, Mohd Amin and published by IGI Global. This book was released on 2020-12-04 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: The uses of nanotechnologies continue to rise exponentially. Due to their multifaceted nature, nanomaterials have a vast amount of potential uses in various scientific professions. Professionals in sectors including agriculture, nutrition, and healthcare are discovering the numerous benefits that nanomaterials carry when applied to traditional practices. In order to understand the dynamic properties of nanomaterials and how to utilize them in specific fields, significant research is required. Applications of Nanomaterials in Agriculture, Food Science, and Medicine is an essential reference source that discusses the emerging development of nanotechnology in various sectors of the scientific community as well as the current benefits and future uses. Industries that the book covers include energy storage and renewable energy, environmental science and wastewater treatment, food and agriculture, and medicine and bioinformatics. This book is ideally designed for researchers, engineers, practitioners, industrialists, educators, strategists, policymakers, scientists, and students seeking coverage on the strategic role of nanomaterials in these imperative fields.
Download or read book Postharvest Biology and Technology of Fruits Vegetables and Flowers written by Gopinadhan Paliyath and published by John Wiley & Sons. This book was released on 2009-03-16 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: An increased understanding of the developmental physiology, biochemistry, and molecular biology during early growth, maturation, ripening, and postharvest conditions has improved technologies to maintain the shelf life and quality of fruits, vegetables, and flowers. Postharvest Biology and Technology of Fruits, Vegetables, and Flowers provides a comprehensive introduction to this subject, offering a firm grounding in the basic science and branching out into the technology and practical applications. An authoritative resource on the science and technology of the postharvest sector, this book surveys the body of knowledge with an emphasis on the recent advances in the field.
