Download or read book Cochrane Handbook for Systematic Reviews of Interventions written by Julian P. T. Higgins and published by Wiley. This book was released on 2008-11-24 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.

Download or read book Cognitive Behavioral Therapy for Tinnitus written by Eldré W. Beukes and published by Plural Publishing. This book was released on 2020-10-28 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many individuals afflicted with tinnitus, the condition causes substantial distress. While there is no known cure for tinnitus, cognitive behavioral therapy (CBT) can offer an effective strategy for managing the symptoms and side effects of chronic tinnitus. Cognitive Behaviorial Therapy for Tinnitus is the first book to provide comprehensive CBT counseling materials specifically developed for the management of tinnitus. This valuable professional book has two primary purposes: to provide clinical guidelines for audiologists who are offering CBT-based counseling for tinnitus and to provide self-help materials for individuals with tinnitus. In addition, these materials may be of interest to researchers developing evidence-based therapies for tinnitus. The book is structured into three sections. Section A provides background information about the theoretical aspects of CBT and some practical tips on how to use this book. Section B provides the CBT counseling, or self-help materials, which can be used by both audiologists and those with tinnitus. Finally, Section C provides some supplementary materials for clinicians that can aid monitoring and engagement of individuals experiencing tinnitus during the course of intervention. Key Features: * The CBT materials contained in this text have been tested in numerous clinical trials across the globe (Australia, Germany, Sweden, United Kingdom, and the United States) both as self-help book chapters and self-help materials delivered via the Internet. * The counseling materials are presented at minimum reading grade level (U.S. 6th grade level) to maximize reader engagement. * The authors of this book have extensive experience in the management of tinnitus, offering useful insights for clinicians and those with tinnitus. * Includes expert advice videos for each chapter to facilitate its adoption to clinical practice.

Download or read book Doing Meta Analysis with R written by Mathias Harrer and published by CRC Press. This book was released on 2021-09-15 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Doing Meta-Analysis with R: A Hands-On Guide serves as an accessible introduction on how meta-analyses can be conducted in R. Essential steps for meta-analysis are covered, including calculation and pooling of outcome measures, forest plots, heterogeneity diagnostics, subgroup analyses, meta-regression, methods to control for publication bias, risk of bias assessments and plotting tools. Advanced but highly relevant topics such as network meta-analysis, multi-three-level meta-analyses, Bayesian meta-analysis approaches and SEM meta-analysis are also covered. A companion R package, dmetar, is introduced at the beginning of the guide. It contains data sets and several helper functions for the meta and metafor package used in the guide. The programming and statistical background covered in the book are kept at a non-expert level, making the book widely accessible. Features • Contains two introductory chapters on how to set up an R environment and do basic imports/manipulations of meta-analysis data, including exercises • Describes statistical concepts clearly and concisely before applying them in R • Includes step-by-step guidance through the coding required to perform meta-analyses, and a companion R package for the book

Download or read book Advances in Meta Analysis written by Terri Pigott and published by Springer Science & Business Media. This book was released on 2012-01-31 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject of the book is advanced statistical analyses for quantitative research synthesis (meta-analysis), and selected practical issues relating to research synthesis that are not covered in detail in the many existing introductory books on research synthesis (or meta-analysis). Complex statistical issues are arising more frequently as the primary research that is summarized in quantitative syntheses itself becomes more complex, and as researchers who are conducting meta-analyses become more ambitious in the questions they wish to address. Also as researchers have gained more experience in conducting research syntheses, several key issues have persisted and now appear fundamental to the enterprise of summarizing research. Specifically the book describes multivariate analyses for several indices commonly used in meta-analysis (e.g., correlations, effect sizes, proportions and/or odds ratios), will outline how to do power analysis for meta-analysis (again for each of the different kinds of study outcome indices), and examines issues around research quality and research design and their roles in synthesis. For each of the statistical topics we will examine the different possible statistical models (i.e., fixed, random, and mixed models) that could be adopted by a researcher. In dealing with the issues of study quality and research design it covers a number of specific topics that are of broad concern to research synthesists. In many fields a current issue is how to make sense of results when studies using several different designs appear in a research literature (e.g., Morris & Deshon, 1997, 2002). In education and other social sciences a critical aspect of this issue is how one might incorporate qualitative (e.g., case study) research within a synthesis. In medicine, related issues concern whether and how to summarize observational studies, and whether they should be combined with randomized controlled trials (or even if they should be combined at all). For each topic, included is a worked example (e.g., for the statistical analyses) and/or a detailed description of a published research synthesis that deals with the practical (non-statistical) issues covered.

Download or read book Introduction to Meta Analysis written by Michael Borenstein and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a clear and thorough introduction to meta-analysis, the process of synthesizing data from a series of separate studies. Meta-analysis has become a critically important tool in fields as diverse as medicine, pharmacology, epidemiology, education, psychology, business, and ecology. Introduction to Meta-Analysis: Outlines the role of meta-analysis in the research process Shows how to compute effects sizes and treatment effects Explains the fixed-effect and random-effects models for synthesizing data Demonstrates how to assess and interpret variation in effect size across studies Clarifies concepts using text and figures, followed by formulas and examples Explains how to avoid common mistakes in meta-analysis Discusses controversies in meta-analysis Features a web site with additional material and exercises A superb combination of lucid prose and informative graphics, written by four of the world’s leading experts on all aspects of meta-analysis. Borenstein, Hedges, Higgins, and Rothstein provide a refreshing departure from cookbook approaches with their clear explanations of the what and why of meta-analysis. The book is ideal as a course textbook or for self-study. My students, who used pre-publication versions of some of the chapters, raved about the clarity of the explanations and examples. David Rindskopf, Distinguished Professor of Educational Psychology, City University of New York, Graduate School and University Center, & Editor of the Journal of Educational and Behavioral Statistics. The approach taken by Introduction to Meta-analysis is intended to be primarily conceptual, and it is amazingly successful at achieving that goal. The reader can comfortably skip the formulas and still understand their application and underlying motivation. For the more statistically sophisticated reader, the relevant formulas and worked examples provide a superb practical guide to performing a meta-analysis. The book provides an eclectic mix of examples from education, social science, biomedical studies, and even ecology. For anyone considering leading a course in meta-analysis, or pursuing self-directed study, Introduction to Meta-analysis would be a clear first choice. Jesse A. Berlin, ScD Introduction to Meta-Analysis is an excellent resource for novices and experts alike. The book provides a clear and comprehensive presentation of all basic and most advanced approaches to meta-analysis. This book will be referenced for decades. Michael A. McDaniel, Professor of Human Resources and Organizational Behavior, Virginia Commonwealth University

Download or read book Systematic Reviews in Health Care written by Matthias Egger and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.

Download or read book Meta Analysis with R written by Guido Schwarzer and published by Springer. This book was released on 2015-10-08 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive introduction to performing meta-analysis using the statistical software R. It is intended for quantitative researchers and students in the medical and social sciences who wish to learn how to perform meta-analysis with R. As such, the book introduces the key concepts and models used in meta-analysis. It also includes chapters on the following advanced topics: publication bias and small study effects; missing data; multivariate meta-analysis, network meta-analysis; and meta-analysis of diagnostic studies.

Download or read book Presenting Medical Statistics from Proposal to Publication written by Janet L. Peacock and published by Oxford University Press. This book was released on 2017-07-21 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: As many medical and healthcare researchers have a love-hate relationship with statistics, the second edition of this practical reference book may make all the difference. Using practical examples, mainly from the authors' own research, the book explains how to make sense of statistics, turn statistical computer output into coherent information, and help decide which pieces of information to report and how to present them. The book takes you through all the stages of the research process, from the initial research proposal, through ethical approval and data analysis, to reporting on and publishing the findings. Helpful tips and information boxes, offer clear guidance throughout, including easily followed instructions on how to: -develop a quantitative research proposal for ethical/institutional approval or research funding -write up the statistical aspects of a paper for publication -choose and perform simple and more advanced statistical analyses -describe the statistical methods and present the results of an analysis. This new edition covers a wider range of statistical programs - SAS, STATA, R, and SPSS, and shows the commands needed to obtain the analyses and how to present it, whichever program you are using. Each specific example is annotated to indicate other scenarios that can be analysed using the same methods, allowing you to easily transpose the knowledge gained from the book to your own research. The principles of good presentation are also covered in detail, from translating relevant results into suitable extracts, through to randomised controlled trials, and how to present a meta-analysis. An added ingredient is the inclusion of code and datasets for all analyses shown in the book on our website (http://medical-statistics.info). Written by three experienced biostatisticians based in the UK and US, this is a step-by-step guide that will be invaluable to researchers and postgraduate students in medicine, those working in the professions allied to medicine, and statisticians in consultancy roles.

Download or read book Mendelian Randomization written by Stephen Burgess and published by CRC Press. This book was released on 2015-03-06 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the Terminology and Methods of Mendelian Randomization for Epidemiological StudiesMendelian randomization uses genetic instrumental variables to make inferences about causal effects based on observational data. It, therefore, can be a reliable way of assessing the causal nature of risk factors, such as biomarkers, for a wide range of disea

Download or read book Dictionary of Pharmacoepidemiology written by Bernard Bégaud and published by John Wiley & Sons. This book was released on 2000-11-08 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by an internationally renowned authority in the field, this is the most complete dictionary devoted specifically to the terms currently used in pharmacoepidemiology. The use of clear and consistent terminology in science has never been more important, and this dictionary, which has been translated from the third edition of a French original, has been reworked to include suggestions made by pharmacoepidemiologists currently using existing versions. It contains revised definitions for nearly all established terms in addition to comprehensive descriptions of new terms and is well illustrated with practical examples. This outstandingly high-quality dictionary will be essential for all those whose work is within or touches upon this field: regulatory authorities, pharmaceutical physicians, lawyers, pharmacists, researchers, evaluators and students.

Download or read book Cross over Trials in Clinical Research written by Stephen S. Senn and published by John Wiley & Sons. This book was released on 2003-07-25 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cross-over trials are an important class of design used in the pharmaceutical industry and medical research, and their use continues to grow. Cross-over Trials in Clinical Research, Second Edition has been fully updated to include the latest methodology used in the design and analysis of cross-over trials. It includes more background material, greater coverage of important statistical techniques, including Bayesian methods, and discussion of analysis using a number of statistical software packages. * Comprehensive coverage of the design and analysis of cross-over trials. * Each technique is carefully explained and the mathematics is kept to a minimum. * Features many real and original examples, taken from the author's vast experience. * Includes discussion of analysis using SAS, S-Plus and, GenStat, StatXact and Excel. * Written in a style suitable for statisticians and physicians alike. * Computer programs to accompany the examples in the book can be downloaded from the Web Primarily aimed at statisticians and researchers working in the pharmaceutical industry, the book will also appeal to physicians involved in clinical research and students of medical statistics.

Download or read book Nonparametric and Distribution free Methods for the Social Sciences written by Leonard A. Marascuilo and published by . This book was released on 1977 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Modern Meta Analysis written by Ton J. Cleophas and published by Springer. This book was released on 2017-05-02 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern meta-analyses do more than combine the effect sizes of a series of similar studies. Meta-analyses are currently increasingly applied for any analysis beyond the primary analysis of studies, and for the analysis of big data. This 26-chapter book was written for nonmathematical professionals of medical and health care, in the first place, but, in addition, for anyone involved in any field involving scientific research. The authors have published over twenty innovative meta-analyses from the turn of the century till now. This edition will review the current state of the art, and will use for that purpose the methodological aspects of the authors' own publications, in addition to other relevant methodological issues from the literature. Are there alternative works in the field? Yes, there are, particularly in the field of psychology. Psychologists have invented meta-analyses in 1970, and have continuously updated methodologies. Although very interesting, their work, just like the whole discipline of psychology, is rather explorative in nature, and so is their focus to meta-analysis. Then, there is the field of epidemiologists. Many of them are from the school of angry young men, who publish shocking news all the time, and JAMA and other publishers are happy to publish it. The reality is, of course, that things are usually not as bad as they seem. Finally, some textbooks, written by professional statisticians, tend to use software programs with miserable menu programs and requiring lots of syntax to be learnt. This is prohibitive to clinical and other health professionals. The current edition is the first textbook in the field of meta-analysis entirely written by two clinical scientists, and it consists of many data examples and step by step analyses, mostly from the authors' own clinical research.

Download or read book Introduction to Randomized Controlled Clinical Trials written by John N.S. Matthews and published by CRC Press. This book was released on 2006-06-26 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evidence from randomized controlled clinical trials is widely accepted as the only sound basis for assessing the efficacy of new medical treatments. Statistical methods play a key role in all stages of these trials, including their justification, design, and analysis. This second edition of Introduction to Randomized Controlled Clinical Trials prov

Download or read book Methods of Meta Analysis written by John E Hunter and published by SAGE. This book was released on 2004-04-07 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the most important developments in meta-analysis from 1990 to 2004, this text presents new patterns in research findings as well as updated information on existing topics.

Download or read book Meta Analysis written by Shahjahan Khan and published by Springer Nature. This book was released on 2020-10-27 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on performing hands-on meta-analysis using MetaXL, a free add-on to MS Excel. The illustrative examples are taken mainly from medical and health sciences studies, but the generic methods can be used to perform meta-analysis on data from any other discipline. The book adopts a step-by-step approach to perform meta-analyses and interpret the results. Stata codes for meta-analyses are also provided. All popularly used meta-analytic methods and models – such as the fixed effect model, random effects model, inverse variance heterogeneity model, and quality effect model – are used to find the confidence interval for the effect size measure of independent primary studies and the pooled study. In addition to the commonly used meta-analytic methods for various effect size measures, the book includes special topics such as meta-regression, dose-response meta-analysis, and publication bias. The main attraction for readers is the book’s simplicity and straightforwardness in conducting actual meta-analysis using MetaXL. Researchers would easily find everything on meta-analysis of any particular effect size in one specific chapter once they could determine the underlying effect measure. Readers will be able to see the results under different models and also will be able to select the correct model to obtain accurate results.

Download or read book Finding What Works in Health Care written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-20 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.