Download or read book Radical Pathways written by Kumar K. Ramakrishna and published by Bloomsbury Publishing USA. This book was released on 2009-03-20 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores two of the most crucial areas of the war on terror: 1) why some Muslims turn to violent jihad, and 2) that process in the world's most populous Muslim nation, Indonesia. The recent history of terrorism in Indonesia has brought this country into the world spotlight: the Bali night club bombing by Islamists in 2002 was one of the worst terrorist attacks in history. The recent violence following the executions of three of the Bali bombers, together with a number of thwarted bomb plots, demonstrate the continuing danger posed by radicalized violent Islamists in the country. Written by one of Southeast Asias leading counter-terrorism experts, Radical Pathways offers innovative new perspectives on the sources of violent Muslim radicalization and what should be done to counter it.
Download or read book Free Radical Damage and its Control written by C.A. Rice-Evans and published by Elsevier. This book was released on 1994-02-09 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive treatise on the chemical and biochemical consequences of damaging free radical reactions, the implications for the pathogenesis of disease and how this might be controlled endogenously and by radical scavenging drugs. Oxidative stress may be influenced by exogenous agents of oxidative stress, radiation, trauma, drug activation, oxygen excess, or by exogenous oxidative stress which is associated with many pathological states including chronic inflammatory disorders, cardiovascular disease, injury to the central nervous system, and connective tissue damage. This and many other such aspects are presented clearly and in depth. The development of antioxidant drugs depends on the understanding of the mechanisms underlying the generation of excessive free radicals in vivo, the factors controlling their release and the site of their action. This excellent volume presents an up-to-date account of the current state of knowledge in these areas.
Download or read book Pathways to Prohibition written by Ann-Marie E. Szymanski and published by Duke University Press. This book was released on 2003-08-21 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Strategies for gradually effecting social change are often dismissed as too accommodating of the status quo. Ann-Marie E. Szymanski challenges this assumption, arguing that moderation is sometimes the most effective way to achieve change. Pathways to Prohibition examines the strategic choices of social movements by focusing on the fates of two temperance campaigns. The prohibitionists of the 1880s gained limited success, while their Progressive Era counterparts achieved a remarkable—albeit temporary—accomplishment in American politics: amending the United States Constitution. Szymanski accounts for these divergent outcomes by asserting that choice of strategy (how a social movement defines and pursues its goals) is a significant element in the success or failure of social movements, underappreciated until now. Her emphasis on strategy represents a sharp departure from approaches that prioritize political opportunity as the most consequential factor in campaigns for social change. Combining historical research with the insights of social movement theory, Pathways to Prohibition shows how a locally based, moderate strategy allowed the early-twentieth-century prohibition crusade both to develop a potent grassroots component and to transcend the limited scope of local politics. Szymanski describes how the prohibition movement’s strategic shift toward moderate goals after 1900 reflected the devolution of state legislatures’ liquor licensing power to localities, the judiciary’s growing acceptance of these local licensing regimes, and a collective belief that local electorates, rather than state legislatures, were best situated to resolve controversial issues like the liquor question. "Local gradualism" is well suited to the porous, federal structure of the American state, Szymanski contends, and it has been effectively used by a number of social movements, including the civil rights movement and the Christian right.
Download or read book Radical Territories in the Brazilian Amazon written by Laura Zanotti and published by University of Arizona Press. This book was released on 2016-11-15 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radical Territories in the Brazilian Amazon sheds light on the creative and groundbreaking efforts Kayapó peoples deploy to protect their lands and livelihoods in Brazil. Laura Zanotti shows how Kayapó communities are using diverse pathways to make a sustainable future for their peoples and lands. The author advances anthropological approaches to understanding how indigenous groups cultivate self-determination strategies in conflict-ridden landscapes.
Download or read book Frontiers of Free Radical Chemistry written by William Pryor and published by Elsevier. This book was released on 2012-12-02 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers of Free Radical Chemistry covers the proceedings of the 1979 symposium on Frontiers of Free Radical Chemistry, held in Louisiana State University Chemistry Department, supported by the Exxon Education Foundation. The contributors discuss the mechanisms of hydrocarbon cracking; oxidation processes; inhibition; and the theory of organic radical reactions, halogenations, and organic peroxide chemistry. This book is organized into three parts encompassing 15 chapters. Part I deals with the understanding of molecular and free radical mechanisms in predicting thermochemical data for radicals and molecules. This part also describes the relationship between distortions of organic molecules and the reactions of pericyclic, ionic, and radical molecules. Part II presents quantitative evaluations of gas phase reactions or carbynes and hydrocarbon pyrolysis and cracking. Discussions on the reactions of free atoms and radicals in the chemistry of the stratosphere and natural troposphere, with an emphasis on the ozone layer and its potential depletion by artificial pollutants, are included in this part. Part III explores the pertinent free radical reactions related to fuel research. Petroleum chemists, researchers, and engineers will find this book invaluable.
Download or read book Radical Self Forgiveness written by Colin Tipping and published by ReadHowYouWant.com. This book was released on 2011-01-26 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most of us have plenty of experience with self-blame and guilt - but we are often at a loss when it comes to forgiving ourselves. According to Colin Tipping, this is because our idea of forgiveness usually requires a victim and a perpetrator - which is impossible when we play both roles at the same time. Tipping's Radical Forgiveness process all...
Download or read book Biomimetic Radical Chemistry and Applications written by Chryssostomos Chatgilialoglu and published by MDPI. This book was released on 2020-03-25 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enormous importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted a strong interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an important research area. When studying free-radical-based chemical mechanisms, biomimetic chemistry and the design of established biomimetic models come into play to perform experiments in a controlled environment that is suitably designed to be in strict connection with cellular conditions. This Special Issue gives the reader a wide overview of biomimetic radical chemistry, where molecular mechanisms have been defined and molecular libraries of products are developed to also be used as traces for the discovery of some relevant biological processes. Several subjects are presented, with 12 articles and 6 reviews written by specialists in the fields of DNA, proteins, lipids, biotechnological applications, and bioinspired synthesis, having “free radicals” as a common denominator.
Download or read book The Chemistry of Radical Polymerization written by Graeme Moad and published by Elsevier. This book was released on 2006 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book commences with a general introduction outlining the basic concepts of radical polymerization. This is followed by a chapter on radical reactions that is intended to lay the theoretical ground-work for the succeeding chapters on initiation, propagation and termination.
Download or read book Ion Radical Organic Chemistry written by Zory Vlad Todres and published by CRC Press. This book was released on 2008-10-20 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consolidating knowledge from a number of disciplines, Ion-Radical Organic Chemistry: Principles and Applications, Second Edition presents the recent changes that have occurred in the field since the publication of the first edition in 2003. This volume examines the formation, transformation, and application of ion-radicals in typical conditions of organic synthesis. Avoiding complex mathematics, the author explains the principles of ion-radical organic chemistry and presents an overview of organic ion-radical reactions. He reviews methods of determining ion-radical mechanisms and controlling ion-radical reactions. Wherever applicable, the text addresses issues relating to ecology and biomedical concerns as well as inorganic participants of the ion-radical organic reactions. After reviewing the nature of organic ion-radicals and their ground-state electronic structure, the book discusses their formation, the relationship between electronic structure and reactivity, mechanism and regulation of reactions, stereochemical aspects, synthetic opportunities, and practical applications. Additional topics include electronic and opto-electronic devices, organic magnets and conductors, lubricants, other materials, and reactions of industrial or biomedical importance. The book concludes by providing an outlook on possible future development in this field. Researchers and practitioners engaged in active work on synthetic or mechanistic organic chemistry and its practical applications will find this text to be invaluable in both its scope and its depth.
Download or read book Free Radical Biology of Endocrine Metabolic Immune Disorders written by Asis Bala and published by Bentham Science Publishers. This book was released on 2022-04-20 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference explores the science of signaling mechanisms associated with diseases like endocrine, metabolic and immune disorders which are linked to oxidative stress mediated disease mechanisms. The common diseases in these categories include diabetes mellitus and arthritis and conditions defined by inflammation and autoimmunity. These diseases involve metabolic pathways mediated by reactive oxygen species or free radicals. The pathways are targets in the mechanism of drugs which aim to treat related disorders. The book covers key topics in free radical biology that help to understand the nature of the pathways and the pharmacology of the drugs that are designed to target them.5 chapters elucidate the free radical biology of the diseases.1. Role of free radical biology in diabetes mellitus2. Role of GSK3 in regulation of insulin release and glucose metabolism3. Regulatory role of NRF2 in rheumatoid arthritis4. Role of free radical biology in Alzheimer’s disease5. Regulatory role of immune cells mediated antibody on rheumatoid arthritis Key features:- Elucidates the key biochemical and pharmacological mechanisms that are mediated by free radicals in common endocrine, metabolic and immune diseases- Explains the activation of immunological factors (like RF and ACPA) that trigger inflammation and arthritis- Covers the role of free radicals in Alzheimer’s disease and new interventions that target mitochondrial mechanisms- Systematically explains the molecular biology of free radicals with the help of schematic diagrams - Includes references for further reading The accessible and structured text in this reference make it a suitable resource for all biomedical scientists, faculty and postgraduate students in academia and industry.
Download or read book Organic Chemistry of Drug Degradation written by Min Li and published by Royal Society of Chemistry. This book was released on 2012-11-30 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: The vast majority of drugs are organic molecular entities. A clear understanding of the organic chemistry of drug degradation is essential to maintaining the stability, efficacy, and safety of a drug product throughout its shelf-life. During analytical method development, stability testing, and pharmaceutical manufacturing troubleshooting activities, one of the frequently occurring and usually challenging events would be the identification of drug degradants and understanding of drug degradation mechanisms and pathways. This book is written by a veteran of the pharmaceutical industry who has first-hand experience in drug design and development, drug degradation mechanism studies, analytical development, and manufacturing process troubleshooting and improvement. The author discusses various degradation pathways with an emphasis on the mechanisms of the underlying organic chemistry, which should aid greatly in the efforts of degradant identification, formulation development, analytical development, and manufacturing process improvement. Organic reactions that are significant in drug degradation will first be reviewed and then illustrated by examples of drug degradation reported in the literature. The author brings the book to a close with a final chapter dedicated to the strategy for rapid elucidation of drug degradants with regard to the current regulatory requirements and guidelines. One chapter that should be given special attention is Chapter 3, Oxidative Degradation. Oxidative degradation is one of the most common degradation pathways but perhaps the most complex one. This chapter employs more than sixty drug degradation case studies with in-depth discussion in regard to their unique degradation pathways. With the increasing regulatory requirements on the quality and safety of pharmaceutical products, in particular with regard to drug impurities and degradants, the book will be an invaluable resource for pharmaceutical and analytical scientists who engage in formulation development, analytical development, stability studies, degradant identification, and support of manufacturing process improvement. In addition, it will also be helpful to scientists engaged in drug discovery and development as well as in drug metabolism studies.
Download or read book Chlorine and Chlorine Compounds in the Paper Industry written by Victor Turoski and published by CRC Press. This book was released on 1997-09-01 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook provides essential information on toxicology, risk assessment, analysis, monitoring, human and ecological effects, treatment alternatives, ecosystem health, compliance, and much more.
Download or read book Radical Pathways written by Kumar K. Ramakrishna and published by Bloomsbury Publishing USA. This book was released on 2009-03-20 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores two of the most crucial areas of the war on terror: 1) why some Muslims turn to violent jihad, and 2) that process in the world's most populous Muslim nation, Indonesia. The recent history of terrorism in Indonesia has brought this country into the world spotlight: the Bali night club bombing by Islamists in 2002 was one of the worst terrorist attacks in history. The recent violence following the executions of three of the Bali bombers, together with a number of thwarted bomb plots, demonstrate the continuing danger posed by radicalized violent Islamists in the country. Written by one of Southeast Asias leading counter-terrorism experts, Radical Pathways offers innovative new perspectives on the sources of violent Muslim radicalization and what should be done to counter it.
Download or read book Reagents for Radical and Radical Ion Chemistry written by David Crich and published by John Wiley & Sons. This book was released on 2013-05-30 with total page 1874 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radicals and radical ions are important intermediates with wide use in organic synthesis. The first book to concentrate on reagents for the creation and use of radicals and radical ions, this new volume in the Handbooks of Reagents for Organic Synthesis series compiles articles taken from the e-eros database, on reagents for use in radical and radical chemistry, to help the chemist in the lab choose the right reagents. Reflecting the enormous growth of radical chemistry over the past ten years, this is an essential guide for all synthetic chemists.
Download or read book Substituent Effects in Radical Chemistry written by Heinz G. Viehe and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the NATO Advanced Research Workshop, Louvain-la-Neuve, Belgium, January 20-24, 1986
Download or read book Free Radical Toxicology written by Kendall B Wallace and published by CRC Press. This book was released on 1997-06-19 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides insight into the involvement of free radicals in the pathogenesis of chemical-induced toxic tissue injury. The text addresses the fundamentals of free radical chemistry and the theoretical basis for electron transfer reaction leading to free radical generation. It describes the various subcellular sources of free radicals, the biological reactivity with lipid, protein and nucleic acids, and the physiochemical determinants of free radical-induced cell injury and the various antioxidant defence systems. The book focuses on target organ toxicity, and the concluding section offers an overview of the evidence implicating free radicals in the aetiology of various chemical toxicities, challenging the possibility of misguided use of biomarkers for oxidative damage.
Download or read book Radical and Radical Ion Reactivity in Nucleic Acid Chemistry written by Michael D. Greenberg and published by John Wiley & Sons. This book was released on 2009-09-22 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive coverage of radical reactive intermediates in nucleic acid chemistry and biochemistry The Wiley Series on Reactive Intermediates in Chemistry and Biology investigates reactive intermediates from the broadest possible range of disciplines. The contributions in each volume offer readers fresh insights into the latest findings, emerging applications, and ongoing research in the field from a diverse perspective. The chemistry and biochemistry of reactive intermediates is central to organic chemistry and biochemistry, and underlies a significant portion of modern synthetic chemistry. Radical and Radical Ion Reactivity in Nucleic Acid Chemistry provides the only comprehensive review of the chemistry and biochemistry of nucleic acid radical intermediates. With contributions by world leaders in the field, the text covers a broad range of topics, including: A discussion of the relevant theory Ionization of DNA Nucleic acid sugar radicals Halopyrimidines Oxidative, reductive, and low energy electron transfer Electron affinity sensitizers Photochemical generative of reactive oxygen species Reactive nitrogen species Enediyne rearrangements Phenoxyl radicals A unique compilation on the cutting edge of our understanding, Radical and Radical Ion Reactivity in Nucleic Acid Chemistry provides an unparalleled resource to student and professional researchers in such fields as organic chemistry, biochemistry, molecular biology, and physical chemistry, as well as the industries associated with these disciplines.
