Download or read book Radiation in Tissue Banking written by Aziz Nather and published by World Scientific. This book was released on 2007 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important book discusses the need for gamma irradiation in the processing of tissue allografts. With particular emphasis on tissue banking in the Asia-Pacific region, it covers a wide range of issues in tissue banking, including the basic science of radiation, quality control of the irradiation process, and clinical applications of irradiated bone grafts and amnions. A compulsory textbook for the well-regarded Singapore-based IAEA/NUS Diploma Course in Tissue Banking, it is also a useful guide for tissue bankers in establishing quality systems in their banks. Whether they be tissue banking students, tissue graft producers, radiation scientists, or transplantation surgeons, readers of this book will discover the latest developments in this exciting interdisciplinary field.
Download or read book Radiation Sterilization of Tissue Allografts written by J. H. Hendry and published by . This book was released on 2007 with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recommendations and guidelines for the safe use of ionizing radiation as a sterilization procedure for tissue allografts. The recommendations were produced by the IAEA with the help and approval of the main professional associations of tissue banks in Europe, Latin America and the USA and by experts in all aspects of radiosterilization and transplantation procedures. The code of practice covers the recommended qualifications of the tissue bank facilities, the tissue donors, the tissue processing and preservation procedures, and the maintenance of validation of the pre-sterilization and sterilization processes. Also covered are the quality, safety and clinical application of the tissue allografts, documentation and certification procedures, management and control issues, establishing a sterilization dose and worked examples.
Download or read book Allograft Procurement Processing and Transplantation written by Aziz Nather and published by World Scientific. This book was released on 2010 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is written as a comprehensive guide for all tissue bank operators to procure and process bone and soft tissue allografts of highest quality standards for safe tissue transplantation practice in patients who require musculoskeletal tissue allograft transplantation. This comprehensive guide includes donor selection criteria, aseptic procurement techniques, laboratory testing and processing of grafts by deep freezing or freeze drying. It also includes sterilization of tissue grafts using gamma irradiation. Quality controls of tissue grafts are discussed in depth. The clinical transplantation of bone and soft tissue allografts is also discussed, with special consideration given to potential complications. Principles of sterile technique in the operating theater are described. The book also incorporates the basic sciences of tissue banking including anatomy, biomechanics, microbiology and immunology. It also covers radiation science so that the reader can better understand radiation sterilization of tissue grafts. Included in the book is a guide for public awareness programmes, radiation code of practice and general standards for tissue banking as recommended by the International Atomic Energy Agency.
Download or read book Radiation Sterilization of Tissue Allografts written by IAEA. and published by . This book was released on 2007 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recommendations and guidelines for the safe use of ionizing radiation as a sterilization procedure for tissue allografts. The recommendations were produced by the IAEA with the help and approval of the main professional associations of tissue banks in Europe, Latin America and the USA and by experts in all aspects of radiosterilization and transplantation procedures. The code of practice covers the recommended qualifications of the tissue bank facilities, the tissue donors, the tissue processing and preservation procedures, and the maintenance of validation of the pre-sterilization and sterili.
Download or read book Radiation sterilization of tissue allografts written by Organizaciòn Internacional de Energìa Atòmica and published by . This book was released on 2007 with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Radiation sterilization of tissue allografts requirements for validation and routine control a code of practice written by and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Sterilisation of Biomaterials and Medical Devices written by Sophie Lerouge and published by Elsevier. This book was released on 2012-09-27 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: The effective sterilisation of any material or device to be implanted in or used in close contact with the human body is essential for the elimination of harmful agents such as bacteria. Sterilisation of biomaterials and medical devices reviews established and commonly used technologies alongside new and emerging processes.Following an introduction to the key concepts and challenges involved in sterilisation, the sterilisation of biomaterials and medical devices using steam and dry heat, ionising radiation and ethylene oxide is reviewed. A range of non-traditional sterilisation techniques, such as hydrogen peroxide gas plasma, ozone and steam formaldehyde, is then discussed together with research in sterilisation and decontamination of surfaces by plasma discharges. Sterilisation techniques for polymers, drug-device products and tissue allografts are then reviewed, together with antimicrobial coatings for ‘self-sterilisation’ and the challenge presented by prions and endotoxins in the sterilisation of reusable medical devices. The book concludes with a discussion of future trends in the sterilisation of biomaterials and medical devices.With its distinguished editors and expert team of international contributors, Sterilisation of biomaterials and medical devices is an essential reference for all materials scientists, engineers and researchers within the medical devices industry. It also provides a thorough overview for academics and clinicians working in this area. Reviews established and commonly used technologies alongside new and emerging processes Introduces and reviews the key concepts and challenges involved in sterilisation Discusses future trends in the sterilisation of biomaterials and medical devices
Download or read book Advances in Tissue Banking written by Glyn O. Phillips and published by World Scientific. This book was released on 2004 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the most comprehensive volume dealing with tissue banking presently available, with 27 contributions from the most distinguished and experienced practitioners in the field: surgeons, microbiologists and tissue bankers. Safety of allografts is now a major concern due to possible microbial and viral contamination of tissues, even in the most sophisticated centres. Thus, publication here of the International Atomic Energy Agency''s Code of Practice for the Radiation Sterilisation of Tissues is important, as is their guidance on Standards and Public Awareness regarding this often misunderstood technology. The volume spans all the methodologies used in the field and covers a spectrum of tissues: bone, skin, cardiovascular grafts, corneal grafts and sperm banking. Of particular interest in these days of gigantic disasters is the evaluation of the value of an effective tissue bank during the Volendam burns disaster in the Netherlands and the horrific disaster in OC Messa RedondaOCO Peru. Orthopaedics, as usual, has the premier usage of tissues and this volume is graced by a landmark contribution from that doyen of massive allograft surgery, Henry Mankin. Balancing out the US experience is a contribution from Russia, which outlines new approaches to using allograft and autograft bone. The motivation for such a comprehensive volume came at the congress held in Boston, which drew together all the international associations of tissue banking: American, Asia-Pacific, Latin American and European. The whole world has been harnessed to construct this outstanding and historic volume. Sample Chapter(s). Chapter 1: The International Atomic Energy Agency (IAEA) Programme in Radiation and Tissue Banking: Past and Present (93 KB). Contents: The Contribution of the International Atomic Energy Agency (IAEA) to Tissue Banking; Safety of Tissue Allografts; Ethical and Social Aspects of Tissue Banking; Tissue Grafts in Orthopaedics; Caradiovascular Grafts; Cornea Grafts; Sperm Banking; Cryopreservation. Readership: Tissue bank operators, orthopaedic surgeons, radiation biologists and government agency policy-makers."
Download or read book The Effect of Gamma Radiation Sterilization on Yield Properties and Microscopic Tissue Damage in Dense Cancellous Bone written by Stephanie J. Dux and published by . This book was released on 2010 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancellous bone allografts are increasingly attractive because the high porosity allows for rapid in-growth and the stiffness closely matches that of the host bone. Allografts are sterilized with gamma radiation which can affect the mechanical properties and damage processes of bone. The purpose of this study was to determine the effects of gamma radiation sterilization on yield properties of dense cancellous bone and identify differences in microdamage accumulation. Compression tests of cylindrical bovine proximal tibia specimens sterilized at a dose of 29.32 kGy and control specimens were conducted to 1.3% strain. Histological sections were obtained to examine microscopic tissue damage. Sterilization had no effect on the yield properties of cancellous bone, but irradiated specimens had higher residual strain and significantly more microscopic tissue damage in the form of microfractures. This suggests that sterilization changes the damage processes of cancellous bone and could affect the performance of an allograft following overloading.
Download or read book The Scientific Basis of Tissue Transplantation written by G. O. Phillips and published by World Scientific. This book was released on 2001 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important book contains in one volume various subjects, including anatomy, physiology, microbiology, radiation sciences, biology of healing of allografts, biomechanics of allografts and transplantation immunology. It is intended for easy and comprehensive use by practitioners in the field of tissue banking and tissue transplantation. It can also serve as a textbook for a course in tissue banking. Sample Chapter(s). Introduction 1: Background (294 KB). Introduction 2: The Present Development (318 KB). Contents: Anatomy; Matrix Biology and Physiology of Tissues; Microbiology: Sterile Techniques; Radiation Sciences; Biology of Healing of Allografts; Biomechanics of Allografts; Immunology. Readership: Tissue bank operators OCo technologists, scientists, orthopaedic surgeons, radiation biologists and plastic surgeons."
Download or read book Ligament Reconstructions written by L'hocine Yahia and published by World Scientific. This book was released on 2021-04-12 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ACL or anterior cruciate ligament is the most important ligament in the knee. When it is completely torn, it can lead to instability or buckling of the knee. There are several options to choose from when selecting a graft for ACL reconstruction such as using autografts including patellar tendon, hamstring tendon, and quadriceps tendon, and allografts (also known as donor tissue or cadaver tissue). Artificial ligaments are also discussed since they are still used in Europe and Asia. This book summarizes the pros and cons of each graft option in detail.
Download or read book Development and Validation of a Novel Method for the Strengthening and Toughening of Irradiation Sterilized Bone Allografts Used in Orthopaedic Reconstructions written by Tarik Attia and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Reconstruction of large skeletal defects is a significant and challenging issue. Large defects can occur due to bone cancer, revision arthroplasty and traumatic injuries. Reconstruction using structural bone allograft is often implemented to repair large skeletal defects. However, sterilizing bone allografts by using gamma-irradiation, which is considered as the most effective sterilization method, causes collagen damage and leads to brittle and weak bone. Our lab has begun to develop a technology, by using a ribose treatment prior irradiation, which protects the bone from the irradiation-induced damage. The aim of this project was to test and verify the ribose treatment through extensive mechanical testing to confirm the effects of our novel method. In addition to the mechanical testing, failure and collagen analysis was performed to understand the protective mechanism of the ribose pre-treatment. Ribose pre-treatment improved the mechanical properties of irradiation sterilized human bone in a pre-treatment concentration-dependent manner. The 1.2M ribose pre-treatment provided >100% of ultimate strength of normal controls and protected 76% of the work-to-fracture (toughness) lost in the irradiated controls. Similarly, the ribose pre-treatment improved the thermo-mechanical properties of irradiation-sterilized human bone collagen in a concentration-dependent manner. Greater free radical content and pentosidine content were modified in the ribose treated bone. The pre-treatment also protected 146% of the fatigue life that was lost in the irradiated controls. Furthermore, using the method of pre-treating bone with ribose prior to irradiation sterilization has some potential to improve irradiation sterilized bone allograft quality while also ensuring the effectiveness of the sterilization process. Collectively, our results suggest that ribose treated bone could be used in the clinical setting and providing bone and tissue banks with allografts with mechanical properties similar to or better than native bones to facilitate bone repair and regeneration.
Download or read book Sterilisation of Tissues Using Ionising Radiations written by J F Kennedy and published by Taylor & Francis US. This book was released on 2005-05-06 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Existing methods and processing for sterilising tissues are proving inadequate in many instances. Infections have been transmitted from the graft to the recipient and in the USA the Centre for Disease Control and other regulatory bodies have drawn attention to the need for a reliable end sterilisation method which does not damage the functionality of the final tissue. Safety of surgical allografts is, therefore, a major concern due to microbial and viral contamination of tissues which is now a problem even in the most sophisticated centres. The Presidents of the main Professional Association of Tissue Banks; American, European and Latin American met in Vienna to review the situation and concluded that the time was opportune to organise an international high level expert meeting, which would identify the best method of using radiation technology to assist in the production of safe tissue allografts Sterilisation of biological tissues with ionising radiations provides the information on this subject presented at an international meeting in Wales, supported by the International Atomic Energy Agency. New methods of protecting the tissues were presented which at the same time allow the use of sufficiently high doses of ionising radiations to inactivate invading organisms. A Code of Practice for the Radiation Sterilisation of Tissues was evaluated and the outcome and the full Code is included in this volume, as well as explorations of all of the methodologies used in the field. Sterilisation of biological tissues with ionising radiations is the only volume of its kind and as such is an invaluable source of information for those working in tissue banks, transplant surgeons and the safety regulators. High-quality papers highlighting the most recent developments in this important area Includes the full code of practice for the radiation sterilisation of tissues Edited by a highly respected team of experts
Download or read book Sterilization and preservation of biological tissues by ionizing radiation report of a Panel on Radiation Sterilization of Biological Tissues for Transplantation organized by the International Atomic Energy Agency and held in Budapest 16 20 june 1969 written by Panel on Radiation Sterilization of Biological Tissues for Transplantation and published by . This book was released on 1970 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Human Amniotic Membrane Basic Science And Clinical Application written by Nazly Hilmy and published by World Scientific. This book was released on 2017-08-23 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive guide for all tissue bank operators to screen, procure and process amniotic membrane for clinical application.The amnion comes close to being the ideal biological membrane or dressing — readily available, inexpensive to procure and process. Its basic science is discussed in detail — anatomy, biological and biomechanical properties.It can be procured from the placenta in normal vaginal deliveries and from Caesarean Sections. Processing is by freeze-drying or by air-drying process with sterilisation using gamma irradiation.The product has low antigenicity, has anti-microbial properties with ability to enhance epithelisation with marked relief of pain. It is useful as a dressing for wounds — flap wounds, burn wounds, injury wounds, diabetic ulcers, leprous ulcers and post-surgery wounds and post-radiation wounds. It is also used as a biological scaffold for cells in tissue engineering. Its ophthalmic applications include treatment of corneal ulcers and conjunctival tumours. Oral uses include gingiva depigmentation and periodontal regeneration.
Download or read book Tendon Regeneration written by Manuela E. Gomes and published by Academic Press. This book was released on 2015-08-08 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes is the first book to highlight the multi-disciplinary nature of this specialized field and the importance of collaboration between medical and engineering laboratories in the development of tissue-oriented products for tissue engineering and regenerative medicine (TERM) strategies. Beginning with a foundation in developmental biology, the book explores physiology, pathology, and surgical reconstruction, providing guidance on biological approaches that enhances tendon regeneration practices. Contributions from scientists, clinicians, and engineers who are the leading figures in their respective fields present recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field. Provides an overview of tendon biology, disease, and tissue engineering approaches Presents modern, alternative approaches to developing functional tissue solutions discussed Includes valuable information for those interested in tissue engineering, tissue regeneration, tissue physiology, and regenerative medicine Explores physiology, pathology, and surgical reconstruction, building a natural progression that enhances tendon regeneration practices Covers recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field
Download or read book Cartilage Restoration written by Jack Farr and published by Springer Science & Business Media. This book was released on 2013-08-15 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Attempting to bridge the gap between the science and art of cartilage restoration, Cartilage Restoration: Practical Clinical Applications combines an overview of clinical research and methodologies with clinical cases to help guide the orthopedic treatment and care of patients presenting with cartilage issues. With chapters written by internationally-renowned orthopedic surgeons, topics include an overview of current surgical options, debridement and marrow stimulation, autograft plug transfer, allografts, cell therapy, and meniscal issues. Cartilage Restoration is a valuable resource for orthopedic surgeons, residents, and fellows.
