Download or read book Radiation Measuring Instruments radiochemicals and accessories written by and published by . This book was released on 1957 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Catalogue Q Nuclear Chicago Corporation written by Nuclear-Chicago Corporation and published by . This book was released on 1957 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Radiological Monitoring Methods and Instruments written by National Committee on Radiation Protection and Measurements (U.S.) and published by . This book was released on 1952 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Radiological Monitoring Methods and Instruments written by United States. National Committee on Radiation Protection and Measurements and published by . This book was released on 1952 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Radioactivity Measuring Instruments written by Malcolm Cuthbert Nokes and published by . This book was released on 1959 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Radiological Monitoring Methods and Instruments written by National Committee on Radiation Protection (U.S.) and published by . This book was released on 1952 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Radiation Protection Measurement written by Hans Kiefer and published by Pergamon. This book was released on 1972 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Radiochemical Procedures written by Ivan Draganić and published by . This book was released on 1962 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Design and Operation of Radiochemical Laboratories written by W. H. Ray and published by . This book was released on 1950 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Trade Catalogs on Radiation Survey Meters X ray Measuring Instruments Components Electrometer Tubes written by Victoreen Instrument Company and published by . This book was released on 1953 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Notes on Radiation Measuring Instruments written by John Daly and published by . This book was released on 1953 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Radiation Protection Instrumentation Radon and Radon Decay Product Measuring Instruments General Principles written by British Standards Institute Staff and published by . This book was released on 2006-09-29 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiation protection, Radiation measurement, Instruments, Radon, Measuring instruments, Radioactive materials, Gases, Calibration, Classification systems, Type testing, Radiation hazards

Download or read book Instruments and Automation written by and published by . This book was released on 1955 with total page 1462 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Radiation Protection Instrumentation Radon and Radon Decay Product Measuring Instruments Equipment for the Production of Reference Atmospheres Containing Radon Isotopes and Their Decay Products STAR written by British Standards Institute Staff and published by . This book was released on 2009-03-31 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiation protection, Radiation measurement, Instruments, Radon, Measuring instruments, Radioactive materials, Gases, Test atmospheres, Radioactive isotopes, Calibration

Download or read book Radiation Detection and Measuring Instruments written by United States. Bureau of the Census and published by . This book was released on 1957 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Microfluidic Tools for Radiochemical Analysis and High throughput Radiopharmaceutical Development written by Jason Jones and published by . This book was released on 2021 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Positron emission tomography (PET) is a highly sensitive non-invasive imaging modality that uses small masses of radiolabeled "tracer" compounds to probe specific biochemical pathways within the whole body. PET is used extensively in clinical diagnostics, basic research, drug development, treatment monitoring, and in the new field of theranostics. To minimize radiation exposure to the radiochemist, the preparation (synthesis, purification and formulation) of PET tracers is performed using automated instruments known as radiosynthesizers. Because current systems are quite expensive, bulky (requiring operation in a specialized radiation-shielded hot cell) and consume tens to hundreds of times as much precursors and reagents compared to the amount of tracer needed for imaging, there has been intense interest in microfluidics in this field. A particular promising avenue has been the use of droplet-based radiochemistry platforms that can produce similar quantities as conventional systems, yet reduce volume and reagents by 100x, reduce synthesis times, and are small enough that they could be self-shielded and operated as a benchtop instrument in a normal laboratory. In addition to advantages for tracer production, this approach enables parallel syntheses by performing multiple reactions together on a single chip, paving the way to rapid, high-throughput radiochemistry for basic investigations, synthesis optimization, and tracer development. In one project, I designed a droplet chemistry heating platform involving a fast ceramic heater for accurate temperature control for a singular droplet synthesis. This initial platform was used in the development of the droplet synthesis of [18F]AMBF3-TATE, realizing an Isolated radiochemical yield (RCY) of 16 1% (n=5) with via isotopic exchange radiofluorination. I also developed a robotic system to perform fully-automated droplet reactions (up to 64 at a time). A Cartesian 3-axis gantry was built that could quickly move a fluidics head (for reagent dispensing and crude product collection) across a 20cm x 40cm workspace containing a set of four multi-reaction chips (each with 16 sites) each controlled by an independent heater, a pipette tip rack, microwell plates for reagents and reaction products, and a set of thin-layer chromatography (TLC) plates for reaction analysis. The system was extensively tested and characterized, and a scripting language was developed to allow high-throughput studies to be programmed as a series of intuitive operation sequences applied to sets of reaction sites. Consistency was assessed by performing a series of identical reactions (synthesis of [18F]Fallypride) which exhibited crude RCY of 79 5% (n=16). This was lower than the manual optimal conditions (90 1%, n=4), and with slightly higher variation. In a second project, I explored microfluidic technology related to the analysis of radiotracers. After the synthesis of a PET tracer, the resulting product must be purified, formulated in saline and finally must pass a number of quality control (QC) tests to ensure safety of the tracer and identity of the product. These tests are typically performed using equipment such as high-performance liquid chromatography (HPLC) which is an expensive instrument that requires significant table space for the device. We designed a "hybrid" capillary and PDMS microfluidic chip for the performance of these QC tests using capillary electrophoresis (CE). I helped develop a volumetric injection chip to inject a 4nL volume of analyte into the separation capillary in a highly repeatable manner. Using this device, injected sample peak relative standard deviation (RSD) was found from the UV absorbance detector electropherogram to be 1.5%, allowing for baseline separation (i.e. resolution 1.5) of FLT from known synthesis impurities, and enabling impurity species to be quantified independently. The major limitation towards this device performing some of the required QC tests was the lack of a method for in situ radiation detection. Therefore, I added an avalanche photodiode (APD) to the previous device for the purpose of detecting radioactive species. This detector provides highly localized detection due to the short positron range and thus narrow peak widths in the radiation detector electropherogram. The radiation detector enabled confirmation of radiochemical identity, and radiochemical purity, and a limit of quantitation of 114 MBq/mL (3.1 mCi/mL), suitable for testing batches of tracers at higher levels of radioactivity concentration.

Download or read book Nucleonics written by and published by . This book was released on 1966 with total page 1406 pages. Available in PDF, EPUB and Kindle. Book excerpt: