Download or read book Quantitative Ultrasound Imaging Parameters for Evaluation of Carotid Atherosclerotic Plaque written by Catherine Steffel and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is a leading cause of death and disability throughout the world. Clinicians recognize that carotid atherosclerotic plaque can be a contributing cause of stroke; however, clinical methods for characterizing carotid plaque with ultrasound are semi-quantitative, and tools are needed to assess plaque composition in asymptomatic individuals who have not yet suffered a stroke or other cerebrovascular event. To examine carotid plaque composition noninvasively and overcome some of these limitations, researchers have developed standardized quantitative ultrasound (QUS) methods based on brightness-mode (B-mode) images and radiofrequency (RF) echo signals. Our research group has been involved in this effort by developing signal processing approaches and evaluating QUS parameters. Some primary challenges of computing QUS parameters, particularly in vivo, are plaques' small sizes and heterogeneous composition. Algorithms developed in recent years reportedly minimize QUS estimation variance in simulation, phantom studies, and biological tissue. The primary goal of the research presented in this dissertation was to adapt some of these new signal processing approaches to carotid plaque assessment and develop and validate subsequent QUS parameters. As part of this work, we applied an optimum power spectral shift estimation (OPSSE) method to RF echo signal data and computed attenuation coefficient and attenuation-corrected integrated backscatter parameters in plaque in vivo and ex vivo. Then, we compared our results to those from a reference phantom method (for in vivo attenuation coefficient estimation only) and to ground-truth assessments of plaque composition (whole plaque surgical scores, assessments of single representative sections of histopathology, and 3D reconstructions of histopathology whole slide images [for ex vivo only]). Our results demonstrated that the OPSSE method may provide QUS estimates with lower variance, fewer nonphysical estimates, and high spatial resolution. Further, attenuation coefficient and attenuation-corrected integrated backscatter parameters correlated with cholesterol, calcium, thrombus, ulceration, hemorrhage, hemosiderin, and inflammation content in plaque and could discriminate among plaque scores. Together, our results suggest that the applied signal processing approaches and developed QUS parameters may provide information about plaque composition that has not been revealed through other parameters and indices obtained as part of our study. This dissertation contributes to a growing body of QUS research that will guide future development of an accurate and reliable tool for assessing risk of plaque rupture or stroke by plaque echogenicity changes.
Download or read book Quantitative Ultrasound and Photoacoustic Imaging for the Assessment of Vascular Parameters written by Kristen M. Meiburger and published by Springer. This book was released on 2016-11-21 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the development of quantitative techniques for ultrasound and photoacoustic imaging in the assessment of architectural and vascular parameters. It presents morphological vascular research based on the development of quantitative imaging techniques for the use of clinical B-mode ultrasound images, and preclinical architectural vascular investigations on quantitative imaging techniques for ultrasounds and photoacoustics. The book is divided into two main parts, the first of which focuses on the development and validation of quantitative techniques for the assessment of vascular morphological parameters that can be extracted from B-mode ultrasound longitudinal images of the common carotid artery. In turn, the second part highlights quantitative imaging techniques for assessing the architectural parameters of vasculature that can be extracted from 3D volumes, using both contrast-enhanced ultrasound (CEUS) imaging and photoacoustic imaging without the addition of any contrast agent. Sharing and summarizing the outcomes of this important research, the book will be of interest to a broad range of researchers and practitioners in the fields of medical imaging and biomedical engineering.
Download or read book Multi Modality Atherosclerosis Imaging and Diagnosis written by Luca Saba and published by Springer Science & Business Media. This book was released on 2013-09-13 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is one of the leading causes of death in the world, resulting mostly from the sudden ruptures of atherosclerosis carotid plaques. Understanding why and how plaque develops and ruptures requires a multi-disciplinary approach such as radiology, biomedical engineering, medical physics, software engineering, hardware engineering, pathological and histological imaging. Multi-Modality Atherosclerosis Imaging, Diagnosis and Treatment presents a new dimension of understanding Atherosclerosis in 2D and 3D. This book presents work on plaque stress analysis in order to provide a general framework of computational modeling with atherosclerosis plaques. New algorithms based on 3D and 4D Ultrasound are presented to assess the atherosclerotic disease as well as very recent advances in plaque multimodality image fusion analysis. The goal of Multi-Modality Atherosclerosis Imaging, Diagnosis and Treatment is to fuse information obtained from different 3D medical image modalities, such as 3D US, CT and MRI, providing the medical doctor with some sort of augmented reality information about the atherosclerotic plaque in order to improve the accuracy of the diagnosis. Analysis of the plaque dynamics along the cardiac cycle is also a valuable indicator for plaque instability assessment and therefore for risk stratification. 4D Ultrasound, a sequence of 3D reconstructions of the region of interest along the time, can be used for this dynamic analysis. Multimodality Image Fusion is a very appealing approach because it puts together the best characteristics of each modality, such as, the high temporal resolution of US and the high spatial resolutions of MRI and CT.
Download or read book Atherosclerotic Plaques written by Robert W. Wissler and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: The philosophy of this NATO Advanced Research Workshop and the monograph it has yielded is that if you put a small number of very talented and creative scientists of different backgrounds and documented accomplishments together in a cloistered place for a few days to consider a very important and timely topic, many new ideas will be generated. The keynote of this conference was the Future. By this we mean the expected future developments of highly reliable sequential quantitative measurements of atherosclerotic plaque size and components in living human subjects. Some of the best minds and the most experienced and talented individuals at the leading edges of imaging of arteries were involved; some of the best scientists and students of the atherosclerotic plaque and its components participated; and some of the leading investigators of the cell biology or, as we call it in the USA, the pathobiology of atherosclerosis, contributed important new information. All of these individuals were actively involved in the conference and each obviously had carefully prepared and was able to communicate effectively.
Download or read book Manual of Neurosonology written by László Csiba and published by Cambridge University Press. This book was released on 2016-04-28 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurosonology is non-invasive, portable, and has excellent temporal resolution, making it a valuable and increasingly popular tool for the diagnosis and monitoring of neurological conditions when compared to other imaging techniques. This guide looks beyond the use of neurovascular ultrasound in stroke to encompass a wide range of other neurological diseases and emergencies. It offers a practical approach to the examination of patients, interpretation of ultrasound studies, and the application of neurosonology to the development of management and treatment strategies. Each chapter incorporates a thorough and clear procedural methodology alongside scanning tips for trainees; this step-by-step approach is further enhanced by example images and focused diagnostic questions. Authored and edited by international experts, this practical manual of neurosonology is an invaluable resource for neurologists, neurosurgeons, intensivists, radiologists, and ultrasonographers.
Download or read book Coronary Angioscopy written by Kyoichi Mizuno and published by Springer. This book was released on 2015-07-03 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a thorough review of coronary angioscopy, ranging from instructions on its use to the latest advances. Starting with the structure and fundamental principles of angioscopy, it shows readers how to apply the image to comprehensive care of coronary-artery patients. Plentiful color photos and illustrations will enable readers to investigate and classify plaques and thrombi and to evaluate coronary stent- and drug-based therapies. The authors are leading researchers on angioscopy. This book offers the perfect guide not only for new clinicians but also for cardiologists who have already adopted this technique for medical examination and treatment. Angioscopy is a unique medical technique for visualizing the interior of blood vessels and helps physicians not only to diagnose the pathology but also to measure the effectiveness of Percutaneous coronary intervention (PCI) or antiarteriosclerotic drugs. Furthermore, the recently developed molecular angioscopy approach allows us to observe Low-density lipoprotein (LDL) oxide, collagen, and macrophages, and is rapidly growing in importance.
Download or read book Ultrasound and Carotid Bifurcation Atherosclerosis written by Andrew Nicolaides and published by Springer Science & Business Media. This book was released on 2011-11-24 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultrasound and Carotid Bifurcation Atherosclerosis provides a comprehensive overview of the most recent advancements in instrumentation, imaging techniques including the use of contrast enhancement agents, plaque image analysis and its automation, elastography and plaque motion analysis; also, the use of ultrasonic and other biomarkers in the detection of the high risk cardiovascular individual. Finally, it deals with the application of IVUS, TCD and carotid plaque characterization in clinical practice and in stroke risk stratification. Ultrasound and Carotid Bifurcation Atherosclerosis is intended for all those working in the field of atherosclerosis, ultrasound imaging and cardiovascular risk, including the clinician, the vascular ultrasonographer, the epidemiologist, the molecular biologist, the biomedical engineer and the informatics scientist. Furthermore, this book bridges the gap between the researcher and the clinician, who is keen to incorporate the latest results of research to his daily practice.
Download or read book Clinical Diagnosis of Atherosclerosis written by M. G. Bond and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the product of a February 1982 conference, cosponsored by the American Heart Association, the National Institutes of Health, and the Bowman Gray School of Medicine, which examined techniques for delineating quantitatively the natural history of atherosclerosis. Against the background of current pathologic and clinical knowledge of atherosclerosis, invasive and noninvasive evaluative methods now in use and under development are surveyed in depth. Correlative clinicopathologic studies of atherosclerosis pose special questions with respect to both luminal and plaque characteristics that are addressed in this volume. An old observa tion, based on the examination of arterial casts, suggested that the so-called nodose lesion of atherosclerosis may be at first flattened into the wall of a weakened, dilated artery, rather than raised into the lumen. This is now fully confirmed in vivo by ultrasonic and other imaging techniques. The morbid anatomist is challenged anew to describe lesions as they are likely to occur in vivo. To achieve closer correlation with natural conditions, perfu sion fixation of arteries under arterial pressure is becoming more widely used and has already demonstrated more valid quantita tion of the composition and configuration of lesions. While the noninvasive methods of B-mode and Doppler ultrasound are suitable only for the clinical study of superficial arteries, such as the carotid or femoral, the new and relatively noninvasive procedure of intravenous digital subtraction angio graphy can be effectively used for the examination of deep systems, such as cerebral vessels.
Download or read book Quantitative Evaluation of Atherosclerotic Plaque Using Ultrasound Tissue Characterization written by Ersin Yigiter and published by . This book was released on 1992 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Noninvasive Vascular Diagnosis written by Ali F. AbuRahma and published by Springer Science & Business Media. This book was released on 2008-05-11 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides the newest definitive text on the current techniques used in assessing vascular disorders. Readers will receive authoritative information and will be guided through the establishment and accreditation of a vascular laboratory and introduced to the physics of diagnostic testing. The chapters comprehensively explain the use of ultrasound in diagnosing cerebrovascular, renovascular, visceral ischemia and peripheral arterial disease, as well as venous disorders and deep abdominal vascular conditions. The book contains over 300 illustrations, many of them in color. The book will be invaluable to physicians who treat vascular disorders, surgeons, cardiologists, vascular radiologists and the vascular laboratory staff.
Download or read book Vascular Medicine A Companion to Braunwald s Heart Disease E Book written by Mark Creager and published by Elsevier Health Sciences. This book was released on 2019-05-22 with total page 963 pages. Available in PDF, EPUB and Kindle. Book excerpt: With authoritative coverage of everything from recent discoveries in the field of vascular biology to recent clinical trials and evidence-based treatment strategies, Vascular Medicine, 3rd Edition, is your go-to resource for improving your patients' cardiovascular health. Part of the Braunwald family of renowned cardiology references, this updated volume integrates a contemporary understanding of vascular biology with a thorough review of clinical vascular diseases, making it an ideal reference for vascular medicine specialists, general cardiologists, interventional cardiologists, vascular surgeons, and interventional radiologists. - Incorporates technologic advances in vascular imaging – including ultrasound, MRI, CTA, and catheter-based angiography – along with more than 230 new figures, providing an up-to-date and complete view of the vascular system and vascular diseases. - Covers novel antithrombotic therapies for peripheral artery disease and venous thromboemboism, advances in endovascular interventions for aortic aneurysms, and today's best surgical treatments for vascular diseases. - Includes seven new chapters: Pathobiology of Aortic Aneurysms; Pathobiology and Assessment of Cardiovascular Fibrosis; Large Vessel Vasculitis; Medium and Small Vessel Vasculitis; Epidemiology and Prognosis of Venous Thromboembolic Disease; Fibromuscular Dysplasia; and Dermatologic Manifestations of Vascular Disease. - Discusses methods for aggressive patient management and disease prevention to ensure minimal risk of further cardiovascular problems. - Keeps you current with ACC/AHA and ECC guidelines and the best ways to implement them in clinical practice. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices
Download or read book Noninvasive Vascular Diagnosis written by Ali F. AbuRahma and published by Springer. This book was released on 2017-10-02 with total page 853 pages. Available in PDF, EPUB and Kindle. Book excerpt: This large format book is the definitive text on vascular surgery written by expert editors and contributors. It is well supported by exceptional illustrative material. The book is invaluable to all those who work in vascular laboratories as wel.l as internists, cardiologists, vascular laboratory directors and staff, general surgeons involved in vascular surgery and the vascular surgery community in general Noninvasive Vascular Diagnosis comprehensively covers all aspects of noninvasive evaluation of the circulatory system in the extremities. The increasing popularity of noninvasive techniques is not reflected in the number of comprehensive works on the topic and it is clear from the success of the first edition that the demand for an updated volume is increasing.
Download or read book Ultrafast Ultrasound Imaging written by Hideyuki Hasegawa and published by MDPI. This book was released on 2018-09-21 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Ultrafast Ultrasound Imaging" that was published in Applied Sciences
Download or read book The Vulnerable Plaque Second Edition written by Ron Waksman and published by CRC Press. This book was released on 2007-06-13 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since publication of the First Edition, advances in the diagnosis and prevention and treatment strategies of the vulnerable plaque have necessitated this greatly expanded second edition. With several new chapters covering mainly diagnostic and treatment options, The Handbook of the Vulnerable Plaque will remain the benchmark text for all interventional cardiologists treating vulnerable patients by providing the physician with comprehensive insight into the world of the vulnerable plaque.
Download or read book Lipoproteins in Health and Disease written by John Betteridge and published by CRC Press. This book was released on 1999-04-02 with total page 1328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive work deals with the major health problem of high lipid levels in blood, a cause of serious heart and vascular disease. Formerly the province only of the chemical pathologist, cardiologists and general physicians are now offering treatment as new 'lipid-lowering' drugs become available. The area is also of considerable interest to public health physicians as changes in lifestyle (such as dietary and smoking habits) have significant effects on lipid levels. A prestigious team of contributors covers all aspects of the topic, from molecular biology to practical dietary management to help reduce lipid levels.
Download or read book Ultrasound Elastography for Biomedical Applications and Medicine written by Ivan Z. Nenadic and published by John Wiley & Sons. This book was released on 2018-10-25 with total page 919 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultrasound Elastography for Biomedical Applications and Medicine Ivan Z. Nenadic, Matthew W. Urban, James F. Greenleaf, Mayo Clinic Ultrasound Research Laboratory, Mayo Clinic College of Medicine, USA Jean-Luc Gennisson, Miguel Bernal, Mickael Tanter, Institut Langevin – Ondes et Images, ESPCI ParisTech CNRS, France Covers all major developments and techniques of Ultrasound Elastography and biomedical applications The field of ultrasound elastography has developed various techniques with the potential to diagnose and track the progression of diseases such as breast and thyroid cancer, liver and kidney fibrosis, congestive heart failure, and atherosclerosis. Having emerged in the last decade, ultrasound elastography is a medical imaging modality that can noninvasively measure and map the elastic and viscous properties of soft tissues. Ultrasound Elastography for Biomedical Applications and Medicine covers the basic physics of ultrasound wave propagation and the interaction of ultrasound with various media. The book introduces tissue elastography, covers the history of the field, details the various methods that have been developed by research groups across the world, and describes its novel applications, particularly in shear wave elastography. Key features: Covers all major developments and techniques of ultrasound elastography and biomedical applications. Contributions from the pioneers of the field secure the most complete coverage of ultrasound elastography available. The book is essential reading for researchers and engineers working in ultrasound and elastography, as well as biomedical engineering students and those working in the field of biomechanics.
Download or read book Radiology of Peripheral Vascular Diseases written by E. Zeitler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive account of the use of modern imaging procedures for the diagnosis of arterial and venous diseases. Each imaging modality is separately considered and applications in individual diseases are then explained with the aid of excellent illustrations. In addition, vascular interventions such as balloon angioplasty, local thrombolysis, and stent implantation are discussed and appraised, with special attention devoted to the problem of radiation burden for patients. The authors are all recognized experts in angiology, phlebology, and interventional radiology.
