Download or read book Quantitative Research in Human Biology and Medicine written by Sigismund Peller and published by Butterworth-Heinemann. This book was released on 2013-10-22 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Research in Human Biology and Medicine reflects the author's past activities and experiences in the field of medical statistics. The book presents statistical material from a variety of medical fields. The text contains chapters that deal with different aspects of vital statistics. It provides statistical surveys of perinatal mortality rate; epidemiology of various diseases, like cancer, tuberculosis, malaria, diphtheria, and scarlatina; and discussions of various aspects of human biology such as growth and development, genetics, and nutrition. The inheritance of mental qualities; the law governing multiple births; and historical demography are covered as well. Medical statisticians and physicians will find the book interesting.
Download or read book Quantitative Methods in Biological and Medical Sciences written by H.O. Lancaster and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: My original intention was to write a history of medical statistics, used in its prewar sense, expanding the writings on the subject by Major Greenwood, from which I formed many of my ideas in the early days immediately after the Second World War. In later years, I decided that the scope of his works was narrower than what I think is appropriate now, for he was writing in an era before the acceptance and use of the Fisherian methods and he was probably not aware of the mathematization of many parts of biological theory. Further, the boundary between the medical and biological sciences has largely disappeared. Many texts have now been written on branches of the theory and practice inspired by R. A. Fisher (see §4. 13). I discuss the history of the use of quantitative methods in the biological sciences, defined after the style of Peller (1967) as that branch of science that uses a quantitative approach to, or quantitative logical reasoning on, or biology. The mathematical tech any issue having to do with medicine niques are various and not classified here. Within the book I use "biological sciences" to include medicine but use the longer phrase in its title to avoid misunderstandings as to content. Moreover, most of the experimental work carried out in medical research laboratories is performed on animals other than man.
Download or read book Quantitative Human Physiology written by Joseph J Feher and published by Academic Press. This book was released on 2017-01-02 with total page 1023 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Human Physiology: An Introduction, winner of a 2018 Textbook Excellence Award (Texty), is the first text to meet the needs of the undergraduate bioengineering student who is being exposed to physiology for the first time, but requires a more analytical/quantitative approach. This book explores how component behavior produces system behavior in physiological systems. Through text explanation, figures, and equations, it provides the engineering student with a basic understanding of physiological principles with an emphasis on quantitative aspects. - Winner of a 2018 Textbook Excellence Award (College) (Texty) from the Textbook and Academic Authors Association - Features a quantitative approach that includes physical and chemical principles - Provides a more integrated approach from first principles, integrating anatomy, molecular biology, biochemistry and physiology - Includes clinical applications relevant to the biomedical engineering student (TENS, cochlear implants, blood substitutes, etc.) - Integrates labs and problem sets to provide opportunities for practice and assessment throughout the course NEW FOR THE SECOND EDITION - Expansion of many sections to include relevant information - Addition of many new figures and re-drawing of other figures to update understanding and clarify difficult areas - Substantial updating of the text to reflect newer research results - Addition of several new appendices including statistics, nomenclature of transport carriers, and structural biology of important items such as the neuromuscular junction and calcium release unit - Addition of new problems within the problem sets - Addition of commentary to power point presentations
Download or read book Quantitative Methods in Biological and Medical Sciences written by H O Lancaster and published by . This book was released on 1994-10-27 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This wide-ranging volume surveys the immense impact that quantitative methods have had on the development of modern biological and medical science. Professor Lancaster begins with the contribution of the Ancient Greek philosophers and then traces the development of fundamental ideas from there to the present day. He shows how mathematics, principally through counting and measurement, and statistics have profoundly influenced the emergence of key ideas and theories. Since no background knowledge of biological anatomy, physiology or disease is required, this volume is essentially a self-contained account. As befits such a wide-ranging volume, amongst the topics covered are: epidemiology, the classification of disease, microbiology, genetics, clinical trials, death rates and life tables, and evolution. All those interested in these topics will find this an invaluable source of information and a remarkable synthesis of the long history of quantification in the biological (including medical) sciences.
Download or read book Basic Science Methods for Clinical Researchers written by Morteza Jalali and published by Academic Press. This book was released on 2017-03-31 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow's clinician scientists and future leaders in discovery science. - Serves as a helpful guide for clinical researchers who lack a conventional science background - Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms - Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data - Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)
Download or read book Beyond the Molecular Frontier written by National Research Council and published by National Academies Press. This book was released on 2003-03-19 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€"into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€"so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€"from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future.
Download or read book Quantitative Methods for Health Research written by Nigel Bruce and published by John Wiley & Sons. This book was released on 2018-02-05 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical introduction to epidemiology, biostatistics, and research methodology for the whole health care community This comprehensive text, which has been extensively revised with new material and additional topics, utilizes a practical slant to introduce health professionals and students to epidemiology, biostatistics, and research methodology. It draws examples from a wide range of topics, covering all of the main contemporary health research methods, including survival analysis, Cox regression, and systematic reviews and meta-analysis—the explanation of which go beyond introductory concepts. This second edition of Quantitative Methods for Health Research: A Practical Interactive Guide to Epidemiology and Statistics also helps develop critical skills that will prepare students to move on to more advanced and specialized methods. A clear distinction is made between knowledge and concepts that all students should ensure they understand, and those that can be pursued further by those who wish to do so. Self-assessment exercises throughout the text help students explore and reflect on their understanding. A program of practical exercises in SPSS (using a prepared data set) helps to consolidate the theory and develop skills and confidence in data handling, analysis, and interpretation. Highlights of the book include: Combining epidemiology and bio-statistics to demonstrate the relevance and strength of statistical methods Emphasis on the interpretation of statistics using examples from a variety of public health and health care situations to stress relevance and application Use of concepts related to examples of published research to show the application of methods and balance between ideals and the realities of research in practice Integration of practical data analysis exercises to develop skills and confidence Supplementation by a student companion website which provides guidance on data handling in SPSS and study data sets as referred to in the text Quantitative Methods for Health Research, Second Edition is a practical learning resource for students, practitioners and researchers in public health, health care and related disciplines, providing both a course book and a useful introductory reference.
Download or read book Research Methodology in the Medical and Biological Sciences written by Petter Laake and published by Academic Press. This book was released on 2007-11-05 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing easy-to-access information, this unique sourcebook covers the wide range of topics that a researcher must be familiar with in order to become a successful experimental scientist. Perfect for aspiring as well as practicing professionals in the medical and biological sciences it discusses a broad range of topics that are common, yet not traditionally considered part of formal curricula. The information presented also facilitates communication across conventional disciplinary boundaries, in line with the increasingly multidisciplinary nature of modern research projects. - Perfect for students with various professional backgrounds providing a broad scientific perspective - Easily accessible, concise material makes learning about diverse methods achievable in today's fast-paced world
Download or read book Quantitative Health Research Issues and Methods written by Elizabeth Curtis and published by McGraw-Hill Education (UK). This book was released on 2013-09-16 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a detailed and comprehensive guide to undertaking quantitative health research at postgraduate and professional level. It takes you through the entire research process, from designing the project to presenting the results and will help you execute high quality quantitative research that improves and informs clinical practice. Written by a team of research experts, this book covers common practical problems such as applying theory to research and analysing data. It also includes chapters on communicating with ethics committees, recruiting samples from vulnerable populations, audit as a research approach, quasi-experimental designs and using cognitive interviewing, making it a new and innovative offering for health researchers. Other topics covered in this book include: Ethical considerations of research Designing and planning quantitative research projects Data measurement and collection Analyzing and presenting resultsWith a strong practical focus, each chapter features examples of real-life research to illustrate the quantitative research process, as well as tips and insights into research planning and execution. This book is an essential guide for all health care professionals undertaking a postgraduate degree, as well as health researchers and practitioners who need to carry out research as part of their professional role. Contributors: Ruth Belling, Michelle Butler, Catherine Comiskey, Siobhan Corrigan, Gloria Crispino, Orla Dempsey, Suzanne Guerin, Maree Johnson, Carmel Kelly, Elaine Lehane, Maria Lohan, Susan McLaren, Deirdre Mongan, Corina Naughton, Rhona O'Connell, Elaine Pierce, Gary Rolfe, Eileen Savage, Anne Scott, Emma Stokes, Roger Watson "“Learning quantitative research is taken much for granted. This is probably why there are fewer generic books on quantitative than qualitative research. This book is long overdue. Clearly- written and well structured, it takes us through the whole journey of a research project from developing 'research questions' to 'presenting the findings', passing through philosophical underpinnings, recruitment of participants and ethical considerations. Written by an array of well-known researchers and teachers, this book will certainly appeal to new as well as seasoned researchers. Those who will use it, will not be disappointed." Kader Parahoo, University of Ulster "The title of this text is somewhat misleading. It is not only an excellent and thorough guide to qualitative health research methods; it is also an excellent introduction to all forms of qualitative research. It takes the reader gently through theoretical and ethical concerns to the practicalities and benefits of utilising qualitative approaches. As such it is that rare thing; a text that can be used by novice researchers to learn their craft, and a key reference resource for experienced research practitioners." Dr. John Cullen, School of Business, National University of Ireland, Maynooth, UK "This is a first-rate collection of essays that promotes an informed understanding of both underpinning principles and widely used techniques. A great deal of effort has clearly been invested in co-ordinating the contributions, and this has delivered clarity, complementarity and effective coverage. This is a welcome, carefully-crafted and very accessible resource that will appeal to students and researchers in healthcare and beyond." Martin Beirne, Professor of Management and Organizational Behaviour, University of Glasgow, Adam Smith Business School, UK
Download or read book Pathobiology of Human Disease written by and published by Elsevier. This book was released on 2014-08-01 with total page 4376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different biological and medical fields, in five basic sections: Human - Organ Systems - Molecular Pathology/Basic Mechanisms of Diseases - Animal Models/Other Model Systems - Experimental Pathology - Clinical Pathology Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students. - Reviews quantitative advances in the imaging and molecular analysis of human tissue, new microarray technologies for analysis of genetic and chromosomal alterations in normal and diseased cells and tissues, and new transgenic models of human disease using conditional, tissue-specific gene targeting - Articles link through to relevant virtual microscopy slides, illustrating side-by-side presentation of "Normal" and "Disease" anatomy and histology images - Fully-annotated with many supplementary full color images, graphs, tables, and video files linked to data sets and to live references, enabling researchers to delve deeper and visualize solutions
Download or read book Quantitative Physiology written by Shangbin Chen and published by Springer Nature. This book was released on 2021-02-09 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stephen Hawking says that the 21st century will be the century of complexity and indeed now systems biology or medicine means dealing with complexity. Both the genome and physiome have emerged in studying complex physiological systems. Computational and mathematical modeling has been regarded as an efficient tool to boost the understanding about living systems in normal or pathophysiological states. Covering applied methodology, basic case studies and complex applications, this volume provides researchers with an overview of modeling and computational studies of physiology (i.e. quantitative physiology), which is becoming an increasingly important branch of systems biology. This book aims to build multi-scale models to investigate functions in living systems and explain how biomolecules, cells, organs, organ systems and organisms carry out the chemical or physical functions. Some of the models addressed are related to gene expression, calcium signalling, neural activity, blood dynamics and bone mechanics. Combining theory and practice, with extensive use of MATLAB, this book is designed to establish a paradigm for quantitative physiology by integrating biology, mathematics, physics and informatics etc. To benefit from this book, the readers are expected to have a background in general physiology and mathematics
Download or read book Oxford Textbook of Medical Education written by Kieran Walsh and published by Oxford University Press. This book was released on 2016 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a comprehensive and evidence-based reference guide for those who have a strong and scholarly interest in medical education, the Oxford Textbook of Medical Education contains everything the medical educator needs to know in order to deliver the knowledge, skills, and behaviour that doctors need. The book explicitly states what constitutes best practice and gives an account of the evidence base that corroborates this. Describing the theoretical educational principles that lay the foundations of best practice in medical education, the book gives readers a through grounding in all aspects of this discipline. Contributors to this book come from a variety of different backgrounds, disciplines and continents, producing a book that is truly original and international.
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1968 with total page 932 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes subject section, name section, and 1968-1970, technical reports.
Download or read book Network Medicine written by Joseph Loscalzo and published by Harvard University Press. This book was released on 2017-02-01 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Big data, genomics, and quantitative approaches to network-based analysis are combining to advance the frontiers of medicine as never before. With contributions from leading experts, Network Medicine introduces this rapidly evolving field of research, which promises to revolutionize the diagnosis and treatment of human diseases.
Download or read book Quantitative Methods for Precision Medicine written by Rongling Wu and published by CRC Press. This book was released on 2022-12-26 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern medicine is undergoing a paradigm shift from a "one-size-fits-all" strategy to a more precise patient-customized therapy and medication plan. While the success of precision medicine relies on the level of pharmacogenomic knowledge, dissecting the genetic mechanisms of drug response in a sufficient detail requires powerful computational tools. Quantitative Methods for Precision Medicine: Pharmacogenomics in Action presents the advanced statistical methods for mapping pharmacogenetic control by integrating pharmacokinetic and pharmacodynamic principles of drug-body interactions. Beyond traditional reductionist-based statistical genetic approaches, statistical formulization in this book synthesizes elements of multiple disciplines to infer, visualize, and track how pharmacogenes interact together as an intricate but well-coordinated system to mediate patient-specific drug response. Features: Functional and systems mapping models to characterize the genetic architecture of multiple medication processes Statistical methods for analyzing informative missing data in pharmacogenetic association studies Functional graph theory of inferring genetic interaction networks from association data Leveraging the concept of epistasis to capture its bidirectional, signed and weighted properties Modeling gene-induced cell-cell crosstalk and its impact on drug response A graph model of drug-drug interactions in combination therapies Critical methodological issues to improve pharmacogenomic research as the cornerstone of precision medicine This book is suitable for graduate students and researchers in the fields of biology, medicine, bioinformatics and drug design and delivery who are interested in statistical and computational modelling of biological processes and systems. It may also serve as a major reference for applied mathematicians, computer scientists, and statisticians who attempt to develop algorithmic tools for genetic mapping, systems pharmacogenomics and systems biology. It can be used as both a textbook and research reference. Professionals in pharmaceutical sectors who design drugs and clinical doctors who deliver drugs will also find it useful.
Download or read book Health Science Research written by Jennifer Peat and published by SAGE. This book was released on 2013-03-01 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: For research to be effective, it is essential that every aspect of the study is well planned. Health Science Research has been written to help researchers from all disciplines conduct their studies with this kind of integrity. Each chapter covers a specific area fo conducting a study, including: - formulating the research question - preparing a grant application - subject recruitment - data collection and analysis - interpreting the results of the study This informative text is designed to be a user friendly research, reference and study tool. It has been organised into eight chapters, each of which covers a specific area of conducting a research study. This book will be of particular value to scientists, research assistants, qualified or trainee physicians, nurses and allied health workers. The book will also be an essential companion for students in all disciplines who want to learn more about how to do good research.
Download or read book The Immortal Life of Henrietta Lacks written by Rebecca Skloot and published by Crown. This book was released on 2010-02-02 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: #1 NEW YORK TIMES BESTSELLER • “The story of modern medicine and bioethics—and, indeed, race relations—is refracted beautifully, and movingly.”—Entertainment Weekly NOW A MAJOR MOTION PICTURE FROM HBO® STARRING OPRAH WINFREY AND ROSE BYRNE • ONE OF THE “MOST INFLUENTIAL” (CNN), “DEFINING” (LITHUB), AND “BEST” (THE PHILADELPHIA INQUIRER) BOOKS OF THE DECADE • ONE OF ESSENCE’S 50 MOST IMPACTFUL BLACK BOOKS OF THE PAST 50 YEARS • WINNER OF THE CHICAGO TRIBUNE HEARTLAND PRIZE FOR NONFICTION NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • Entertainment Weekly • O: The Oprah Magazine • NPR • Financial Times • New York • Independent (U.K.) • Times (U.K.) • Publishers Weekly • Library Journal • Kirkus Reviews • Booklist • Globe and Mail Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave. Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of. Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah. Deborah was consumed with questions: Had scientists cloned her mother? Had they killed her to harvest her cells? And if her mother was so important to medicine, why couldn’t her children afford health insurance? Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.
