Download or read book Quantitative Imaging Study of Breast Cancer written by Gurpreet Singh and published by LAP Lambert Academic Publishing. This book was released on 2012-03 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volumetric measurement using the mammography has been done in the work which can help significantly for evaluating therapeutic response. The ability to accurately calculate the in vivo volume of tumors also has been achieved in this work. In vivo tumor volume measurement using mammography is the main strength of this study. The volume using the mammography will have been the advantage as a response evaluation tool. It can be routinely used in clinical oncology practice. Tumor volume is a more representative quantity of three dimensional tumor mass which is generally of irregular shape and size. The present study underlines the use of Doppler as its cheap examine tool for evaluation the chemotherapy response. It is another significant contribution to the existing literature. Restivity Index (RI), Pulsatility Index (PI) and peak systolic velocity are the Doppler parameters for evaluation of the drug response in cancer patients. Clinical study of the various antioxidant levels like r-SOD, r-GPx, r-catalase and FRAP observed at respective intervals after various cycles of chemotherapy and mastectomy in case of breast cancer has been done.
Download or read book Quantitative imaging and artificial intelligence in breast tumor diagnosis written by Xiang Zhang and published by Frontiers Media SA. This book was released on 2023-02-13 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Contrast Enhanced Mammography written by Marc Lobbes and published by Springer. This book was released on 2019-04-29 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive guide to contrast-enhanced mammography (CEM), a novel advanced mammography technique using dual-energy mammography in combination with intravenous contrast administration in order to increase the diagnostic performance of digital mammography. Readers will find helpful information on the principles of CEM and indications for the technique. Detailed attention is devoted to image interpretation, with presentation of case examples and highlighting of pitfalls and artifacts. Other topics to be addressed include the establishment of a CEM program, the comparative merits of CEM and MRI, and the roles of CEM in screening populations and monitoring of response to neoadjuvant chemotherapy. CEM became commercially available in 2011 and is increasingly being used in clinical practice owing to its superiority over full-field digital mammography. This book will be an ideal source of knowledge and guidance for all who wish to start using the technique or to learn more about it.
Download or read book Diseases of the Chest Breast Heart and Vessels 2019 2022 written by Juerg Hodler and published by Springer. This book was released on 2019-02-19 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As such, it presents a comprehensive review of current knowledge on imaging of the heart and chest, as well as thoracic interventions and a selection of "hot topics". The book is intended for radiologists, however, it is also of interest to clinicians in oncology, cardiology, and pulmonology.
Download or read book Quantitative MRI in Cancer written by Thomas E. Yankeelov and published by Taylor & Francis. This book was released on 2011-09-13 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Propelling quantitative MRI techniques from bench to bedside, Quantitative MRI in Cancer presents a range of quantitative MRI methods for assessing tumor biology. It includes biophysical and theoretical explanations of the most relevant MRI techniques as well as examples of these techniques in cancer applications.The introductory part of the book c
Download or read book Quantitative Three Dimensional Ultrasonic Mammography written by and published by . This book was released on 1999 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this research, improved diagnosis of breast cancer by quantitative, high-resolution three-dimensional ultrasonic imaging, is being reached by a thorough program that synthesizes recent advances in tissue modeling, adaptive imaging, instrumentation, and signal processing. The goal of three-dimensional quantitative imaging is currently being achieved using novel time-domain inverse scattering methods invented by the Principal Investigator and coworkers. Nonlinear forms of these methods provide a robust approach to adaptive imaging that is based on compensation for three-dimensional scattering from actual breast tissue structure. A crucial aspect of the research is the use of realistic tissue models for ultrasonic propagation through breast tissue. Tissue modeling techniques employ tissue maps obtained from specimen cross sections as well as from newly available high-resolution volume photographic data. Calculated scattering from these tissue models will provide accurate characterization of ultrasonic propagation within breast tissue and will also provide realistic data for quantitative imaging algorithms. Synthesis of these breakthroughs will make possible new mammographic applications of ultrasound that will provide clinicians with previously unavailable quantitative information and image detail. The end result will be a lower-cost, more effective, and safer modality for diagnosis, detection, and monitoring of breast cancer.
Download or read book Mammography and Beyond written by National Research Council and published by National Academies Press. This book was released on 2001-07-23 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each year more than 180,000 new cases of breast cancer are diagnosed in women in the U.S. If cancer is detected when small and local, treatment options are less dangerous, intrusive, and costly-and more likely to lead to a cure. Yet those simple facts belie the complexity of developing and disseminating acceptable techniques for breast cancer diagnosis. Even the most exciting new technologies remain clouded with uncertainty. Mammography and Beyond provides a comprehensive and up-to-date perspective on the state of breast cancer screening and diagnosis and recommends steps for developing the most reliable breast cancer detection methods possible. This book reviews the dramatic expansion of breast cancer awareness and screening, examining the capabilities and limitations of current and emerging technologies for breast cancer detection and their effectiveness at actually reducing deaths. The committee discusses issues including national policy toward breast cancer detection, roles of public and private agencies, problems in determining the success of a technique, availability of detection methods to specific populations of women, women's experience during the detection process, cost-benefit analyses, and more. Examining current practices and specifying research and other needs, Mammography and Beyond will be an indispensable resource to policy makers, public health officials, medical practitioners, researchers, women's health advocates, and concerned women and their families.
Download or read book Breast MRI Interpretation written by Gillian M. Newstead and published by Thieme. This book was released on 2021-01-06 with total page 709 pages. Available in PDF, EPUB and Kindle. Book excerpt: State-of-the-art resource details effective breast MRI techniques for improved screening and diagnosis Magnetic resonance imaging (MRI) of the breast has evolved into an important breast cancer screening tool and major advance in women's health. Breast MRI is currently the most sensitive detection technique for both non-invasive and invasive cancers and follow-up in women with a new breast cancer diagnosis. It is increasingly becoming the go-to imaging method for screening women at high and intermediate risk of breast cancer and those with dense breast tissue on mammography. Yet despite its reliability and growing use, many radiologists lack the expertise to accurately perform breast MR image interpretation. Breast MRI Interpretation: Text and Case Analysis for Screening and Diagnosis by Gillian M. Newstead reflects insights and expertise from one of the leading authorities on breast imaging. The book is a highly practical reference on evaluation and interpretation of breast MR imaging, with discussion of the modality as a screening and diagnostic tool. Topics include image acquisition and interpretation, clinical implementation, managing findings, and overcoming problems. Key Highlights About 3,000 illustrations from the University of Chicago including single selected images, side-by-side images at different time points and acquisition parameters, and 3-D images enhance understanding of breast imaging Discussion of advanced acquisition techniques and future potential applications including non-contrast imaging, quantitative dynamic imaging, and artificial intelligence using advanced computer analytic methods This remarkable resource streamlines the breast MRI process, enabling radiologists to incorporate this imaging modality into practice, conduct screening and diagnostic exams more efficaciously, and interpret findings accurately.
Download or read book Breast MRI Interpretation written by Gillian M. Newstead and published by Thieme. This book was released on 2021-01-06 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: State-of-the-art resource details effective breast MRI techniques for improved screening and diagnosis Magnetic resonance imaging (MRI) of the breast has evolved into an important breast cancer screening tool and major advance in women's health. Breast MRI is currently the most sensitive detection technique for both non-invasive and invasive cancers and follow-up in women with a new breast cancer diagnosis. It is increasingly becoming the go-to imaging method for screening women at high and intermediate risk of breast cancer and those with dense breast tissue on mammography. Yet despite its reliability and growing use, many radiologists lack the expertise to accurately perform breast MR image interpretation. Breast MRI Interpretation: Text and Case Analysis for Screening and Diagnosis by Gillian M. Newstead reflects insights and expertise from one of the leading authorities on breast imaging. The book is a highly practical reference on evaluation and interpretation of breast MR imaging, with discussion of the modality as a screening and diagnostic tool. Topics include image acquisition and interpretation, clinical implementation, managing findings, and overcoming problems. Key Highlights About 3,000 illustrations from the University of Chicago including single selected images, side-by-side images at different time points and acquisition parameters, and 3-D images enhance understanding of breast imaging Discussion of advanced acquisition techniques and future potential applications including non-contrast imaging, quantitative dynamic imaging, and artificial intelligence using advanced computer analytic methods This remarkable resource streamlines the breast MRI process, enabling radiologists to incorporate this imaging modality into practice, conduct screening and diagnostic exams more efficaciously, and interpret findings accurately.
Download or read book Hyperpolarized 13c Magnetic Resonance Spectroscopic Imaging of Breast Cancer written by Erin Beth Macdonald and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast cancer is one of the leading causes of cancer-related deaths in women worldwide, owing largely to metastatic disease. However, this disease lacks personalized treatment plans due to an incomplete understanding of the microenvironmental forces driving tumorigenesis and corresponding prognostic markers. Dysregulated metabolism has been identified as an emerging hallmark of cancer, with ample observations that malignant tumors exhibit upregulated glycolysis and increased conversion of pyruvate to lactate regardless of oxygen availability. Additionally, tumor lactate levels have been significantly positively correlated with the development of distant metastases. The advent of hyperpolarized 13C magnetic resonance spectroscopic imaging (MRSI) has enabled real-time assessment of the conversion of pyruvate to lactate in vivo. This aim of this work was to improve the accuracy and precision of metabolic quantification with hyperpolarized 13C MRSI in order to compare in vivo glycolytic rates in murine breast cancer models of different metastatic potential. This work involved several technical advances to increase hyperpolarized 13C-labeled metabolite SNR in the breast cancer tumors and to improve the accuracy and precision of metabolic imaging measures. A number of studies in this work were also designed to characterize the repeatability of quantitative hyperpolarized 13C metabolic measures, a little-explored metric in the field of hyperpolarized 13C MRI. With the culmination of all technical advances enabling reliable metabolic imaging and quantification, a final study comparing glycolytic metabolism in two murine breast cancer models of different metastatic potential was performed. The tested quantitative imaging measures of pyruvate-to-lactate conversion displayed a trend towards increased values in the more metastatic tumor model compared to a tumor model of metastatic dormancy, although this result was not significant for the given study population size. Therefore, the technical advances in this work, and the results of the breast cancer study presented herein, suggest promise for in vivo assessment of glycolytic metabolism with hyperpolarized 13C MRSI in breast cancer models. Furthermore, augmenting glycolytic measures with metabolic rates of complementary pathways may help to develop a more well-rounded understanding of in vivo energy metabolism in breast cancer in the future.
Download or read book Breast Imaging written by Christoph I. Lee and published by Oxford University Press. This book was released on 2018 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast Imaging presents a comprehensive review of the subject matter commonly encountered by practicing radiologists and radiology residents in training. This volume includes succinct overviews of breast cancer epidemiology, screening, staging, and treatment; overviews of all imaging modalities including mammography, tomosynthesis, ultrasound, and MRI; step-by-step approaches for image-guided breast interventions; and high-yield chapters organized by specific imaging finding seen on mammography, tomosynthesis, ultrasound, and MRI. Part of the Rotations in Radiology series, this book offers a guided approach to breast imaging interpretation and techniques, highlighting the nuances necessary to arrive at the best diagnosis and management. Each chapter contains a targeted discussion of an imaging finding which reviews the anatomy and physiology, distinguishing features, imaging techniques, differential diagnosis, clinical issues, key points, and further reading. Breast Imaging is a must-read for residents and practicing radiologists seeking a foundation for the essential knowledge base in breast imaging.
Download or read book Breast MRI written by Katja Pinker and published by Academic Press. This book was released on 2022-09-22 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast MRI: State of the Art and Future Directions provides a comprehensive overview of the current applications of breast MRI, including abbreviated MRI, as well as presenting technical recommendations, practical implementation and associated challenges in clinical routine. In addition, the book introduces novel MRI techniques, multimodality imaging, and advanced image processing coupled with AI, reviewing their potential for impeding and future clinical implementation. This book is a complete reference on state-of-the-art breast MRI methods suitable for MRI researchers, radiographers and clinicians.Breast cancer is one of the leading causes of death among women with early detection being the key to improved prognosis and survival. Magnetic resonance imaging (MRI) of the breast is undisputedly the most sensitive imaging method to detect cancer, with a higher detection rate than mammography, digital breast tomosynthesis, and ultrasound. - Spans the whole spectrum of breast MRI, including basic imaging techniques, indications, interpretation, and the latest cutting-edge techniques - Reviews multiparametric MRI and abbreviated protocols, providing an outlook on the future of this technique - Discusses the predictive and prognostic value of MRI as well as the evolving field of radiomics/genomics and AI
Download or read book Low Dose 3D Quantitative Vascular X ray Imaging of the Breast written by Pablo Milioni de Carvalho and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Background: Worldwide, breast cancer is the most common cancer and second deadliest cancer in women. Diagnostic imaging techniques are a critical part for screening, diagnosis, tumor staging and cancer therapy of the breast. Contrast-Enhanced Magnetic Resonance Imaging (CE-MRI) is the current standard imaging technique allowing detection of abnormal vascular development and lesion contrast uptake. CE-MRI is however very costly and not widely available. Moreover, its spatial resolution might not be sufficient to depict certain types of lesions including microcalcifications. The development of Contrast-Enhanced Spectral Mammography (CESM) has made the clinical use of intravenous contrast enhancement with conventional mammography possible. However, CESM is a 2D projection technique and therefore presents limitations to depict the 3D internal structures of lesions and to provide accurate quantitative 3D functional information.Contrast-Enhanced Digital Breast Tomosynthesis (CE-DBT) and dedicated Contrast-Enhanced Breast CT (CE-bCT) are two breast imaging modalities currently under investigation by academic and industrial research groups. It is however anticipated that the quantitative potential of CE-DBT is limited, due to the inherent low depth-resolution of limited opening angle DBT modality. CE-bCT with quasi-isotropic spatial resolution and voxel signal intensity proportional to the linear attenuation coefficient is believed to offer more accurate quantitative information, though a low-dose operation is still a challenge.Objectives: The purpose of this thesis has been to study the technical feasibility of CE-bCT and its potential to accurately depict and localize tumors, as well as to provide accurate quantitative morphological and functional imaging information about tumors, at low radiation dose levels. To understand the incremental value of CE-bCT over CE-DBT, the quantitative potential of both technologies have been compared. This investigation has been performed through computer simulations.Methods: At first, a simulation platform capable of modeling various X-ray breast imaging techniques and providing radiographic images of simple and complex computational phantoms was developed and validated. Secondly, an optimization study of a CE-bCT technique based on a dual-energy approach was performed, aiming to maximize image quality of iodine-enhanced and morphological images. Finally, the quantitative potential of CE-bCT and CE-DBT was compared through the assessment of iodine-enhanced lesion detectability, characterization, localization and 3D extent measurement. In a human observer study, depiction and characterization of iodine-enhanced lesions of different sizes, shapes and iodine uptakes was compared between CE-bCT and CE-DBT using a mesh-based anthropomorphic breast phantom.Conclusions: The simulation studies in this PhD thesis suggest that dual-energy iodine-injected CE-bCT could be a feasible technique for breast tumor depiction, localization and characterization, with dose levels comparable to standard mammography. While preliminary comparisons with CE-DBT suggests comparable depiction and characterization performance, the fully 3D information combined with high spatial resolution confirms CE-bCT as an interesting low-dose evolution of CESM toward 3D quantitative assessment of contrast uptakes and potential alternative to.
Download or read book Digital Breast Tomosynthesis written by Alberto Tagliafico and published by Springer. This book was released on 2016-05-03 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive description of the screening and clinical applications of digital breast tomosynthesis (DBT) and offers straightforward, clear guidance on use of the technique. Informative clinical cases are presented to illustrate how to take advantage of DBT in clinical practice. The importance of DBT as a diagnostic tool for both screening and diagnosis is increasing rapidly. DBT improves upon mammography by depicting breast tissue on a video clip made of cross‐sectional images reconstructed in correspondence with their mammographic planes of acquisition. DBT results in markedly reduced summation of overlapping breast tissue and offers the potential to improve mammographic breast cancer surveillance and diagnosis. This book will be an excellent practical teaching guide for beginners and a useful reference for more experienced radiologists.
Download or read book Imaging Biomarkers written by Luis Martí-Bonmatí and published by Springer. This book was released on 2016-11-03 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to cover all aspects of the development of imaging biomarkers and their integration into clinical practice, from the conceptual basis through to the technical aspects that need to be considered in order to ensure that medical imaging can serve as a powerful quantification instrument capable of providing valuable information on organ and tissue properties. The process of imaging biomarker development is considered step by step, covering proof of concept, proof of mechanism, image acquisition, image preparation, imaging biomarker analysis and measurement, detection of measurement biases (proof of principle), proof of efficacy and effectiveness, and reporting of results. Sources of uncertainty in the accuracy and precision of measurements and pearls and pitfalls in gold standards and biological correlation are discussed. In addition, practical use cases are included on imaging biomarker implementation in brain, oncologic, cardiovascular, musculoskeletal, and abdominal diseases. The authors are a multidisciplinary team of expert radiologists and engineers, and the book will be of value to all with an interest in the quantitative imaging of biomarkers in personalized medicine.
Download or read book Digital Mammography written by Etta D. Pisano and published by Lippincott Williams & Wilkins. This book was released on 2004 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bogen er en grundlæggende lærebog om digital mammografi, hvori digital mammografi og traditionel mammografi også sammenlignes i forhold til screening, diagnoser og radiografisk billedteknik. Der er en komplet billedsamling af cases indenfor digital mammografi.
Download or read book Developing Technologies for Early Detection of Breast Cancer written by National Research Council and published by National Academies Press. This book was released on 2000-07-06 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt: In November 1999, the Institute of Medicine, in consultation with the Commission on Life Sciences, the Commission on Physical Sciences, Mathematics, and Applications, and the Board on Science, Technology and Economic Policy launched a one year study on technologies for early detection of breast cancer. The committee was asked to examine technologies under development for early breast cancer detection, and to scrutinize the process of medical technology development, adoption, and dissemination. The committee is gathering information on these topics for its report in a number of ways, including two public workshops that bring in outside expertise. The first workshop on "Developing Technologies for Early Breast Cancer Detection" was held in Washington DC in February 2000. The content of the presentations at the workshop is summarized here. A second workshop, which will focus on the process of technology development and adoption, will be held in Washington, DC on June 19-20. A formal report on these topics, including conclusions and recommendations, will be prepared by the committee upon completion of the one-year study.
