Download or read book Quality Control and Safety Evaluation of Natural Products written by Xiaohui Ma (editor.) and published by . This book was released on 2016 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural medicines are derived from natural sources such as plants, animals and/or mineral origins. The use of traditional natural products is an empirical healthcare system based on thousands of years of human experience. Over the past few decades, quality control and safety evaluation methods for natural products, though sophisticated and technologically advanced, still lack comprehensiveness and practicability to some extent. Generally, those methods fully satisfy the modern scientific requirements for extraction, identification, purity, quality and pharmacological effects in the assessment of chemical drugs. However, they are not suitable for handling the complex chemical characteristics of natural products. Therefore, a better understanding of the basic properties of natural medicines and advanced chemical, pharmacological and biological techniques would facilitate the application of the natural products in public health. The purpose of this book is to address the issues mentioned above and present related solutions. The book covers the below topics: *Advanced analytical technologies in the application of the natural medicines (e.g. mass spectrometry, gas or liquid chromatography, and NMR). *Recent advances in biochemistry research of natural medicines (e.g. gene expression microarray, tissue microarray, and chromatin-precipitation assay) *Innovations in analytical chemistry of natural products *Quality control and safety evaluation of traditional medical material and finished products *Detection of low quality and adulterants of natural product *Identification of the plant by various analytical techniques *Regulations and management of natural products from foreign countries *Novel cell-based models used for the high-throughput screening for drug discovery in natural products *Pharmacological effects of natural products in vitro and in vivo *Advanced modeling techniques used in pharamcokinetic and pharmacodynamic properties of natural products (e.g. Pharsight WINNONLIN, Simcyp, and Gastroplus)
Download or read book Quality Control and Evaluation of Herbal Drugs written by Pulok K. Mukherjee and published by Elsevier. This book was released on 2019-05-30 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development. Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs' activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development. - Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes - Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis - Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine - Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues - References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities
Download or read book Poisonous Plants and Phytochemicals in Drug Discovery written by Andrew G. Mtewa and published by John Wiley & Sons. This book was released on 2020-12-22 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their applications in chemistry and in pharmacology. Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career
Download or read book Fingerprinting Analysis and Quality Control Methods of Herbal Medicines written by Ravindra Kumar Pandey and published by CRC Press. This book was released on 2018-07-03 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the increase in the consumption of herbal medicine, there is a need to know which scientifically based methods are appropriate for assessing the quality of herbal medicines. Fingerprinting has emerged as a suitable technique for quality estimation. Chemical markers are used for evaluation of herbal medicines. Identification and quantification of these chemical markers are crucial for quality control of herbal medicines. This book provides updated knowledge on methodology, quality assessment, toxicity analysis and medicinal values of natural compounds.
Download or read book Quality Control of Herbal Medicines and Related Areas written by Yukihiro Shoyama and published by BoD – Books on Demand. This book was released on 2011-11-04 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors of this thematic issue provide a comprehensive summary of most recent knowledge and references on quality control in wide fields. Quality control is essential for natural products like natural medicine and related food products. In this issue fifteen chapters have been included, discussing in detail various aspects of quality control. It will certainly prove useful not only for phytochemical researchers, but also many scientists working in numerous fields. Much effort has been invested by the contributors to share current information. Without their efforts and input 'Quality Control of Herbal Medicine and Related Areas' could not exist.
Download or read book Quality Control Methods for Medicinal Plant Materials written by World Health Organization and published by World Health Organization. This book was released on 1998 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of test procedures for assessing the identity, purity, and content of medicinal plant materials, including determination of pesticide residues, arsenic and heavy metals. Intended to assist national laboratories engaged in drug quality control, the manual responds to the growing use of medicinal plants, the special quality problems they pose, and the corresponding need for international guidance on reliable methods for quality control. Recommended procedures - whether involving visual inspection or the use of thin-layer chromatography for the qualitative determination of impurities - should also prove useful to the pharmaceutical industry and pharmacists working with these materials.
Download or read book Quality Control of Herbal Drugs written by Pulok K. Mukherjee and published by . This book was released on 2002 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Quality control for efficacy and safety of herbal medicinal products written by Jian-bo Yang and published by Frontiers Media SA. This book was released on 2023-06-27 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Evidence Based Validation of Herbal Medicine written by Pulok K. Mukherjee and published by Elsevier. This book was released on 2022-07-12 with total page 858 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evidence-Based Validation of Herbal Medicines: Translational Research on Botanicals brings together current thinking and practice in the characterization and validation of natural products. The book describes different approaches and techniques for evaluating the quality, safety and efficacy of herbal medicine, particularly methods to assess their activity and understand compounds responsible and their probable underlying mechanisms of action. This book brings together the views, expertise and experiences of scientific experts in the field of medicinal plant research, hence it will be useful for researcher who want to know more about the natural lead with their validation and also useful to exploit traditional medicines. - Includes state-of-the-art methods for detecting, isolating and performing structure elucidation by degradation and spectroscopic techniques - Highlights the trends in validation and value addition of herbal medicine with different scientific approaches used in therapeutics - Contains several all-new chapters on topics such as traditional-medicine-inspired drug development to treat emerging viral diseases, medicinal plants in antimicrobial resistance, TLC bio profiling, botanicals as medicinal foods, bioprospecting and bioassay-guided isolation of medicinal plants, immunomodulators from medicinal plants, and more
Download or read book Herbal Medicine written by Iris F. F. Benzie and published by CRC Press. This book was released on 2011-03-28 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef
Download or read book Natural Medicines written by Dilip Ghosh and published by CRC Press. This book was released on 2019-07-18 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: Globally, natural medicine has been considered as an important alternative to modern allopathic medicine. Although natural medicines are popular in society, only limited medicinal herbs have been scientifically evaluated for their potential in medical treatment. This book connects various aspects of the complex journey from traditional medicine to modern medicine. It provides information on topics including global regulations and regulatory hurdles, diverse nutritional challenges and potential health benefits, novel food innovations especially seed-to-clinic approaches, and future trends. FEATURES • Provides information on sustainable use of natural products in the development of new drugs and clinically validated herbal remedies • Discusses issues on evaluation and clinical aspects of herbal medicine, promotion and development, safety evaluation, metabolite profiling, biomarker analysis, formulation, and stability testing • Describes traditional uses of natural medicine through identification, isolation and structural characterization of their active components • Elucidates mechanisms of biological action, adverse effects and identification of their molecular targets of natural medicine • Multidisciplinary appeal including chemistry, pharmacology, pharmacognosy and cell and molecular biology, as well as integration with clinical medicine This book serves as an essential guide for individuals researching natural medicines, and industry employees in areas including drug development, pharmacology, natural products chemistry, clinical efficacy, ethnopharmacology, pharmacognosy, phytotherapy, phyto-technology and herbal science.
Download or read book Recent Advances in Natural Products Science written by Ahmed Al-Harrasi and published by CRC Press. This book was released on 2022-07-21 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a summarized information related to the global herbal drug market and its regulations, ethnopharmacology of traditional crude drugs, isolation of phytopharmaceuticals, phytochemistry, standardization, and quality assessment of crude drugs. Natural products science has constantly been developing with comprehensive data contemplating different parts of natural drugs, such as global trade, quality control and regulatory concerns, traditional medicine systems, production and utilization of drugs, and utilization of medicinal and aromatic plants. This broad information about crude drugs gives rise to a subject that is now recognized as advance natural products science. By contemplating all of this thorough knowledge of the areas, this book is intended to provide considerably to the natural products science. The area of natural products science involves a broad range of topics, such as the pharmacognostical, phytochemical, and ethno-pharmacological aspects of crude drugs. Each chapter gives a sufficient understanding to academicians and researchers in the respective topic. This book includes 40 illustrations and descriptions of roughly 80 medicinal plants used for herbal medicine. The book is an imperative source for all researchers, academicians, students, and those interested in natural products science. FEATURES Includes advance knowledge and detailed developments in natural products science Discusses the most important phytopharmaceuticals used in the pharmaceutical industry Explores the analysis and classification of novel plant-based medicinal compounds Includes standardization, quality control, and global trade of natural products Gives a deep understanding related to recent advances in herbal medicines to treat various ailments Discusses national and WHO regulations and policies related to herbal medicines Covers the complete profile of some important traditional medicinal plants, especially their historical background, biology, and chemistry
Download or read book Quality Control in Toxicology written by George Edward Paget and published by . This book was released on 1977 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Botanical Dietary Supplements written by Gail B. Mahady and published by CRC Press. This book was released on 2001-06-01 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides reviews and details of the quality, safety and efficacy for some of the top-selling botanicals worldwide, including black cohosh, chamomile, comfrey, echinacea, garlic, ginkgo, ginseng, kava, milk thistle, St John's wort and valerian. The work was written based on a systematic review of the scientific literature from 1975-2000.;Each review includes a brief introduction, a section on quality including a definition of the crude drug, geographical distribution, and a listing of the major chemical constituents. The safety and efficacy sections summarize the medical uses, pharmacology, contraindications, warnings, precautions, adverse reactions, dose and dosage forms. The safety and efficacy sections were written for a busy health-care professional, and should enable one to ascertain which clinical uses are supported by clinical data, without having to read through all the pharmacology. Each chapter is fully referenced, enabling the reader to access further information when necessary.
Download or read book Toxicology of Herbal Products written by Olavi Pelkonen and published by Springer. This book was released on 2017-03-07 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive overview of the hazards inherent in herbal medicinal products, with systematic coverage of major toxicities. Topics include composition and quality control, toxicokinetics, interactions, safety pharmacology, approaches to studying complex mixtures including metabolomics and systems network pharmacology, and long-term toxicity. The volume also discusses various organ toxicities with a special emphasis on basic mechanisms of actions and the multicomponent and multi-target nature of herbal products. It concludes with a look to future challenges and opportunities. With contributions from noted experts, Toxicology of Herbal Products is a necessary resource for physicians, pharmacists, and toxicologists interested in complex plant-derived products.
Download or read book WHO Guidelines on Safety Monitoring of Herbal Medicines in Pharmacovigilance Systems written by World Health Organization and published by . This book was released on 2004-01-01 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt: Safety is a fundamental principle in the privision of herbal medicines and herbal products for health care and a critical component of quality control. These guidelines provide practical technical guidance for monitoring the safety of herbal medicines with pharmacovigilance systems.
Download or read book Registries for Evaluating Patient Outcomes written by Agency for Healthcare Research and Quality/AHRQ and published by Government Printing Office. This book was released on 2014-04-01 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.
