Download or read book Progressive Brain Disorders in Childhood written by Juan M. Pascual and published by Cambridge University Press. This book was released on 2017-04-20 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of childhood neurodegenerative and other progressive but non-degenerative disorders to guide their diagnosis and management.
Download or read book Pyruvate Carboxylase written by Keech and published by CRC Press. This book was released on 2018-10-24 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a welcome source of information on this enzyme which is vitally important to many forms of life. Each chapter or section of each volume is not written primarily for those specializing in that narrow area, but rather to provide a coherent and integrated summary of that aspect got those working on other, quite different facets of the same enzyme.
Download or read book Physician s Guide to the Diagnosis Treatment and Follow Up of Inherited Metabolic Diseases written by Nenad Blau and published by Springer. This book was released on 2014-07-08 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, combining and updating two previous editions, is a unique source of information on the diagnosis, treatment, and follow-up of metabolic diseases. The clinical and laboratory data characteristic of rare metabolic conditions can be bewildering for both clinicians and laboratory personnel. Reference laboratory data are scattered, and clinical descriptions may be obscure. The Physician’s Guide documents the features of more than five hundred conditions, grouped according to type of disorder, organ system affected (e.g. liver, kidney, etc) or phenotype (e.g. neurological, hepatic, etc). Relevant clinical findings are provided and pathological values for diagnostic metabolites highlighted. Guidance on appropriate biochemical genetic testing is provided. Established experimental therapeutic protocols are described, with recommendations on follow-up and monitoring. The authors are acknowledged experts, and the book will be a valuable desk reference for all who deal with inherited metabolic diseases.
Download or read book Inborn Metabolic Diseases written by K. Tada and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each disease-related chapter begins with a detailed description of the patient and the delineating symptoms used for establishing the diagnosis and differential diagnosis. The highly detailed figures illustrate the metabolic derangement in a uniform way, together with essential aspects of the genetics involved, thus affording clarification and better understanding of the treatment. Topics covered range from general aspects such as the clinical approach, emergency treatment, diagnostic procedures, and psychosocial care for the child and the family, to specific discussions of new modes of treatment, including liver, bone marrow transplantation and somatic gene therapy.
Download or read book Biomarkers in Inborn Errors of Metabolism written by Uttam Garg and published by Elsevier. This book was released on 2017-06-07 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers of Inborn Errors in Metabolism: Clinical Aspects and Laboratory Determination is structured around the new reality that laboratory testing and biomarkers are an integral part in the diagnosis and treatment of inherited metabolic diseases. The book covers currently used biomarkers as well as markers that are in development. Because biomarkers used in the initial diagnosis of disease may be different than the follow-up markers, the book also covers biomarkers used in both the prognosis and treatment of inherited metabolic disorders. With the introduction of expanded new-born screening for inborn metabolic diseases, an increasing numbers of laboratories are involved in follow-up confirmatory testing. The book provides guidance on laboratory test selection and interpreting results in patients with suspected inherited metabolic diseases. The book provides comprehensive guidance on patient diagnosis and follow-up through its illustrative material on metabolic pathways, genetics and pathogenesis, treatment and prognosis of inherited metabolic diseases, along with essential information on clinical presentation. Each chapter is organized with a uniform, easy-to-follow format: a brief description of the disorder and pathway; a description of treatment; biomarkers for diagnosis; biomarkers followed for treatment efficacy; biomarkers followed for disease progression; confounding conditions that can either: affect biomarker expression or mimic IEMs; other biomarkers: less established, future. - Provides comprehensive information on the tests/biomarkers selection in newborn screening and follow-up of newborn screens - Categorizes biomarkers into diagnostic markers, disease follow-up markers, and prognostic biomarkers - Covers confounding factors that can alter biomarkers in the absence of inborn errors of metabolism - Offers guidance on how to distinguish acquired causes from inborn errors of metabolism
Download or read book Pyruvate Carboxylase written by Keech and published by CRC Press. This book was released on 2018-10-24 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a welcome source of information on this enzyme which is vitally important to many forms of life. Each chapter or section of each volume is not written primarily for those specializing in that narrow area, but rather to provide a coherent and integrated summary of that aspect got those working on other, quite different facets of the same enzyme.
Download or read book The Glutamate GABA Glutamine Cycle written by Arne Schousboe and published by Springer. This book was released on 2016-11-25 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamental biochemical studies of basic brain metabolism focusing on the neuroactive amino acids glutamate and GABA combined with the seminal observation that one of the key enzymes, glutamine synthetase is localized in astroglial cells but not in neurons resulted in the formulation of the term “The Glutamate-Glutamine Cycle.” In this cycle glutamate released from neurons is taken up by surrounding astrocytes, amidated by the action of glutamine synthetase to glutamine which can be transferred back to the neurons. The conversion of glutamate to glutamine is like a stealth technology, hiding the glutamate molecule which would be highly toxic to neurons due to its excitotoxic action. This series of reactions require the concerted and precise interaction of a number of enzymes and plasma membrane transporters, and this volume provides in-depth descriptions of these processes. Obviously such a series of complicated reactions may well be prone to malfunction and therefore neurological diseases are likely to be associated with such malfunction of the enzymes and transporters involved in the cycle. These aspects are also discussed in several chapters of the book. A number of leading experts in neuroscience including intermediary metabolism, enzymology and transporter physiology have contributed to this book which provides comprehensive discussions of these different aspects of the functional importance of the glutamate-glutamine cycle coupling homeostasis of glutamatergic, excitatory neurotransmission to basic aspects of brain energy metabolism. This book will be of particular importance for students as well as professionals interested in these fundamental processes involved in brain function and dysfunction.
Download or read book Basic Neurochemistry written by George J. Siegel and published by Lippincott Raven. This book was released on 1999 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Illustrations by Lorie M. Gavulic, MFA Sponsored by the American Society for Neurochemistry.
Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Download or read book Prokaryotic Metabolism and Physiology written by Byung Hong Kim and published by Cambridge University Press. This book was released on 2019-05-16 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive and up-to-date review of key metabolic processes in bacteria and archaea and how metabolism is regulated under various conditions.
Download or read book Elsevier s Integrated Review Biochemistry written by John W. Pelley, PhD and published by Elsevier Health Sciences. This book was released on 2011-11-30 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Effectively merge basic science and clinical skills with Elsevier's Integrated Review Biochemistry, by John W. Pelley, PhD. This concise, high-yield title in the popular Integrated Review Series focuses on the core knowledge in biochemistry while linking that information to related concepts from other basic science disciplines. Case-based questions at the end of each chapter enable you to gauge your mastery of the material, and a color-coded format allows you to quickly find the specific guidance you need. Online access via www.studentconsult.com - included with your purchase - allows you to conveniently access the book's complete text and illustrations online as well as relevant content from other Student Consult titles. This concise and user-friendly reference provides crucial guidance for the early years of medical training and USMLE preparation. Spend more time reviewing and less time searching thanks to an extremely focused, "high-yield" presentation. Gauge your mastery of the material and build confidence with both case-based, andUSMLE-style questions that provide effective chapter review and quick practice for your exams. Access the full contents online at www.studentconsult.com where you'll find the complete text and illustrations, "Integration Links" to bonus content in other Student Consult titles, an interactive community center with a wealth of additional resources, and much more! Grasp and retain vital concepts more easily thanks to a color-coded format, succinct,text, key concept boxes, and dynamic illustrations that facilitate learning in a highly visual approach. Effectively review for problem-based courses with the help of text boxes that help you clearly see the clinical relevance of the material. Great for visual learners!
Download or read book Photosynthetic Nitrogen Assimilation and Associated Carbon and Respiratory Metabolism written by C.H. Foyer and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to many textbooks, carbohydrates are the photosynthesis and mitochondrial respiration fluctuate in a circadian manner in almost every unique final products of plant photosynthesis. However, the photoautotrophic production of organic organism studied. In addition, external triggers and environmental influences necessitate precise and nitrogenous compounds may be just as old, in appropriate re-adjustment of relative flux rates, to evolutionary terms, as carbohydrate synthesis. In the algae and plants of today, the light-driven assimilation prevent excessive swings in energy/resource provision of nitrogen remains a key function, operating and use. This requires integrated control of the alongside and intermeshing with photosynthesis and expression and activity of numerous key enzymes in respiration. Photosynthetic production of reduced photosynthetic and respiratory pathways, in order to carbon and its reoxidation in respiration are necessary co-ordinate carbon partioning and nitrogen assim- ation. to produce both the energy and the carbon skeletons required for the incorporation of inorganic nitrogen This volume has two principal aims. The first is to into amino acids. Conversely, nitrogen assimilation provide a comprehensive account of the very latest developments in our understanding of how green is required to sustain the output of organic carbon cells reductively incorporate nitrate and ammonium and nitrogen. Together, the sugars and amino acids into the organic compounds required for growth.
Download or read book The Carbonic Anhydrases written by W.R. Chegwidden and published by Birkhäuser. This book was released on 2013-11-11 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbonic anhydrase (CA) is a seemingly ubiquitous enzyme of profound physiological importance, which plays essential roles in respiration, acid-base homeostasis, bone resorption, calcification, photosynthesis, several biosynthetic pathways and a variety of processes involving ion, gas and fluid transfer. This enzyme, which is present in at least three gene families (a, ß, ?), has found favour as a model for the study of evolution of gene families and for site-directed mutagenesis in structure/function relationships, for protein folding and for transgenic and gene target studies. Since the early use of CA inhibitors as diuretics and in treating congestive heart failure, the enzyme has been target of considerable clinical attention. Much of this is now focused on endeavours to produce a new generation of such drugs for the effective treatment of glaucoma and other potential applications. Recent data, suggesting links between CA and various disease processes, including cancer, have stimulated further...
Download or read book Pyruvate Carboxylase Its Interactions with Acetyl CoA written by Yee Sim Khew-Goodall and published by . This book was released on 1985 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Passing the USMLE written by Ahmad Wagih Abdel-Halim and published by Springer Science & Business Media. This book was released on 2009-02-27 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preparing for the USMLE can be a stressful and time consuming task for any medical student. The key elements of a successful review program are clarity, brevity and memory-assisting consistency. The author of Passing the USMLE: Clinical Knowledge has taken great pains to distill an ocean of knowledge down to the fundamental clinical applications of patient care. Covering internal medicine, dermatology, obstetrics, gynecology, surgery, pediatrics and psychology, a wealth of high yield information is presented so the reader takes away as much as possible from every word, every sentence, and every minute spent studying. Passing the USMLE: Clinical Knowledge is illustrated throughout with full color photographs and illustrations.
Download or read book Pyruvate Carboxylase written by Jura N. Gailiusis and published by . This book was released on 1965 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book An Introduction to Agricultural Biochemistry written by J.M. Chesworth and published by Springer Science & Business Media. This book was released on 1998 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Agricultural Biochemistry focuses on the chemistry of plant and animal metabolism and the biomolecules that are involved in these pathways, and then goes on to discuss strategies adopted for processing nutrients.
