Download or read book Current Challenges in Pharmacovigilance written by World Health Organization and published by . This book was released on 2001-01-01 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: In spite of recent progress in the harmonization of terminology and processes affecting work on the clinical safety of medicines consensus is needed on standards for many difficult aspects of day-to-day pharmacovigilance that continue to pose problems for both the pharmaceutical industry and drug regulators. The CIOMS V Working Group has generated proposals for pragmatic approaches to dealing with such issues as: classification and handling of individual safety case reports from a variety of sources (spontaneous consumer reports solicited reports literature the Internet observational studies and secondary data bases disease and other registries regulatory ADR databases and licensor-licensee interactions); new approaches to case management and regulatory reporting practices (proper clinical evaluation of cases incidental vs other events patient and reporter identifiability seriousness criteria expectedness criteria case follow-up criteria and the role and structure of case narratives); improvements and efficiencies in the format content and reporting of periodic safety update reports (PSURs) (including results of an industry survey on PSUR workloads and practices; proposals for high case volume and long time-period reports simplification of certain PSURs summary bridging reports addendum reports license renewal reports for EU and Japan dealing with old products and other technical details); determination and use of population exposure (denominator) data (sources of data and a guide to analytical approaches for a variety of circumstances).The Group has also taken stock of the current state of expedited and periodic clinical safety reporting requirements around the world with summary data on regulations from more than 60 countries. Recommendations are made for enhancing the harmonization steps already taken as a result of previous CIOMS publications and the ICH process. In addition to dealing with unfinished and unresolved issues from previous CIOMS initiatives the report covers many emerging topics such as those involving new technologies. Its 20 Appendices provide a wealth of detailed explanations and reference information. It is the most comprehensive and recent treatment of difficult pharmacovigilance issues affecting the working practices and systems of drug safety and other pharmaceutical professionals.

Download or read book Navy and Marine Corps Awards Manual written by United States. Bureau of Naval Personnel and published by . This book was released on with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Tailored Deterrence written by Barry R. Schneider and published by . This book was released on 2012 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Gold written by Christopher Corti and published by CRC Press. This book was released on 2009-12-02 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gold is used in a wide range of industrial and medical applications and accounts for over 10 percent of the annual demand for metal, worth billions of dollars annually. While much has been written about the mystique and trade of gold, very little has been written about the science and technology in which it is involved. Edited by two respected auth

Download or read book Handbook of Gynecology written by Donna Shoupe and published by Springer Nature. This book was released on 2024-01-07 with total page 1295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive, up-to-date reference on general and subspecialty gynecology. Covering all aspects of gynecology commonly encountered in day-to-day practice, this exhaustive and fully updated new edition provides a practical, one-stop reference work for clinicians working in the field. This carefully-designed volume includes ten sections, beginning with comprehensive coverage of office-based gynecology, and continuing on to present disease processes and management information by patient age group. Each chapter includes background information, current recommendations for screening, diagnostic criteria, common and uncommon associated problems, approach to diagnosis, summary of treatment options, and an overview of ICD-10 codes for specific diagnoses. Importantly, many areas that are covered in the handbook as subspecialty problems are pertinent and important information to many of the general practitioners who handle and develop some expertise in these areas. These include ovulation induction, medical management of incontinence, management of abnormal Pap smears, and work-up of abnormal bleeding. The handbook concludes with an easy-to-navigate presentation of minimally-invasive operations, surgical procedures, neoplasms, and pathology. Advantages and risks associated with management of particular diseases are covered, along with multiple tips for avoiding complications. This second edition is fully updated. With extensive updates on cervical cancer screening, pelvic organ prolapse, and more, many chapters will be completely rewritten to reflect the latest guidelines, procedures, and methods of care in women’s health. The text additionally includes two new chapters, covering the impact of COVID on gynecology care, and the work-up and surgical management of chronic pelvic pain. This is an ideal guide for practicing gynecologists, family and internal medicine physicians, physician assistants, nurse practitioners, fellows, residents, medical students, and all women’s health care providers.

Download or read book Animal Growth Regulation written by Dennis R. Campion and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biotechnological advances of recent years have put us on the brink of unprecedented gains in animal productivity. Manipulation of animal growth rate and composition of gain is now possible by a variety of techniques. Ex amples include ingestion of beta-adrenergic agonists, injection of somatotropin, castration, immunization, and gene insertion. Animal Growth Regulation ad dresses modem concepts of growth regulation with an emphasis on agricul turally important animals. This emphasis is not exclusive, as many situations exist in which the only information available was generated in other species, and this information has been included for the sake of clarity and completeness. However, because of the overall orientation of this volume, particular attention has been given to the regulation of skeletal muscle, adipose tissue, and bone growth. Certain hormones and growth factors have a profound influence on growth regulation and this basic physiological knowledge is being harnessed to maniplilate growth. Thus, considerable emphasis has been given to growth hor mone-somatomedinlinsulinlike growth factor regulation of cell and tissue growth. The involvement of peptides coded by protooncogenes and of negative growth regulators, such as transforming growth factor-l3, represents an emerging area of molecular biology wherein basic knowledge offers potential exploitation for growth manipulation. Opportunities also exist for regulation of protein turn over, especially from the standpoint of protein degradation. Therefore, a place was reserved for these topics in order to provide relevant basic knowledge.

Download or read book Memoirs of Extraordinary Popular Delusions and the Madness of Crowds written by Charles Mackay and published by IndyPublish.com. This book was released on 1852 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Excerpt from Memoirs of Extraordinary Popular Delusions, Vol. 2 A forest huge of spears and thronging helms Appear'd, and serried shields, in thick array. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.

Download or read book Defence Diplomacy in the Long War written by Patrick Blannin and published by BRILL. This book was released on 2017-08-28 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most dominant security issues of the twenty-first century has been the US led battle against transnational terrorism – the aptly named Long War. Over the past fifteen years the Long War has been examined using multiple perspectives. However, one central mechanism is missing in current Long War analyses: defence diplomacy. Defence diplomacy enhances the diplomatic and security capacity of a state, providing the only link between executive office and the ministries of foreign affairs and defence, two vital institutions in the Long War. Using a case study of US defence diplomacy in Afghanistan from 2001 to 2014, the paper argues simply that the practice of defence diplomacy far outweighs current theories on what it is, how it works and why it matters. The paper aims to generate a more nuanced understanding of defence diplomacy, as well as identify it as a key component of the US CT/COIN strategy to achieve their Long War policy objectives.

Download or read book Women s International Thought A New History written by Patricia Owens and published by Cambridge University Press. This book was released on 2021-01-07 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first cross-disciplinary history of women's international thought, analysing leading international thinkers of the twentieth century.

Download or read book Discovering Life Manufacturing Life written by Pierre V. Vignais and published by Springer Science & Business Media. This book was released on 2010-06-21 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Francis BACON, in his Novum Organum, Robert BOYLE, in his Skeptical Chemist and René DESCARTES, in his Discourse on Method; all of these men were witnesses to the th scientific revolution, which, in the 17 century, began to awaken the western world from a long sleep. In each of these works, the author emphasizes the role of the experimental method in exploring the laws of Nature, that is to say, the way in which an experiment is designed, implemented according to tried and tested te- niques, and used as a basis for drawing conclusions that are based only on results, with their margins of error, taking into account contemporary traditions and prejudices. Two centuries later, Claude BERNARD, in his Introduction to the Study of Experimental Medicine, made a passionate plea for the application of the experimental method when studying the functions of living beings. Twenty-first century Biology, which has been fertilized by highly sophisticated techniques inherited from Physics and Chemistry, blessed with a constantly increasing expertise in the manipulation of the genome, initiated into the mysteries of information techn- ogy, and enriched with the ever-growing fund of basic knowledge, at times appears to have forgotten its roots.

Download or read book Dictionary of Abbreviations in Medical Sciences written by Rolf Heister and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not everyone is a friend of the manifold abbreviations that have by now beCome a part of the scientific language of medicine. In order to avoid misunderstanding these abbreviations, it is wise to refer to a reliable dic tionary, such as this one prepared by Heister. The abbreviation ED means, for instance, effective dose to the pharmacologist. However, it might also stand for emetic dose. Radiologists use the same abbreviation for erythema dose, and ED could also mean ethyl dichlorarsine. A com mon meaning of ECU is European currency unit, a meaning that might not be very often in scientific medical publications. ECU, however, also means environmental control unit or European Chiropractic Union. Hopefully, those making inventions and discoveries will make use of Heister's dictionary before creating new abbreviations when preparing manuscripts for scientific publications. It is a very worthwhile goal not to use the same abbreviation for several different terms, especially if it is already widely accepted to mean only one of them. It may be impossible, however, to achieve this goal in different scientific disciplines. Therefore, although it is wise for the abbreviations used in a publication to be defined, it is also very helpful for readers and writers to use a dictionary such as this one. The author deserves our warmest thanks since we know that compiling such a comprehensive dictionary is based upon incredibly hard effort.

Download or read book The Modernist Papers written by Fredric Jameson and published by Verso Books. This book was released on 2016-03-08 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cultural critic Fredric Jameson, renowned for his incisive studies of the passage of modernism to postmodernism, returns to the movement that dramatically broke with all tradition in search of progress for the first time since his acclaimed A Singular Modernity . The Modernist Papers is a tour de froce of anlysis and criticism, in which Jameson brings his dynamic and acute thought to bear on the modernist literature of the nineteenth and twentieth centuries. Jameson discusses modernist poetics, including intensive discussions of the work of Baudelaire, Rimbaud, Mallarmé, Wallace Stevens, Joyce, Proust, and Thomas Mann. He explores the peculiarties of the American literary field, taking in William Carlos Williams and the American epic, and examines the language theories of Gertrude Stein. Refusing to see modernism as simply a Western phenomenon he also pays close attention to its Japanese expression; while the complexities of a late modernist representation of twentieth-century politics are articulated in a concluding section on Peter Weiss’s novel The Aesthetics of Resistance. Challenging our previous understanding of the literature of this pperiod, this monumental work will come to be regarded as the classic study of modernism.

Download or read book Why Muslim Integration Fails in Christian Heritage Societies written by Claire L. Adida and published by Harvard University Press. This book was released on 2016 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amid mounting fears of violent Islamic extremism, many Europeans ask whether Muslim immigrants can integrate into historically Christian countries. In a groundbreaking ethnographic investigation of France’s Muslim migrant population, Why Muslim Integration Fails in Christian-Heritage Societies explores this complex question. The authors conclude that both Muslim and non-Muslim French must share responsibility for the slow progress of Muslim integration. “Using a variety of resources, research methods, and an innovative experimental design, the authors contend that while there is no doubt that prejudice and discrimination against Muslims exist, it is also true that some Muslim actions and cultural traits may, at times, complicate their full integration into their chosen domiciles. This book is timely (more so in the context of the current Syrian refugee crisis), its insights keen and astute, the empirical evidence meticulous and persuasive, and the policy recommendations reasonable and relevant.” —A. Ahmad, Choice

Download or read book Fiber Fueled written by Will Bulsiewicz, MD and published by Penguin. This book was released on 2020-05-12 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The instant New York Times, USA Today, and Publisher's Weekly bestseller A bold new plant-based plan that challenges popular keto and paleo diets, from an award-winning gastroenterologist. The benefits of restrictive diets like paleo and keto have been touted for more than a decade, but as renowned gastroenterologist Dr. Will Bulsiewicz, or "Dr. B," illuminates in this groundbreaking book, the explosion of studies on the microbiome makes it abundantly clear that elimination diets are in fact hazardous to our health. What studies clearly now show--and what Dr. B preaches with his patients--is that gut health is the key to boosting our metabolism, balancing our hormones, and taming the inflammation that causes a host of diseases. And the scientifically proven way to fuel our guts is with dietary fiber from an abundant variety of colorful plants. Forget about the fiber your grandmother used to take--the cutting-edge science on fiber is incredibly exciting. As Dr. B explains, fiber energizes our gut microbes to create powerhouse postbiotics called short-chain fatty acids (SCFAs) that are essential to our health. SCFAs are scientifically proven to promote weight loss, repair leaky gut, strengthen the microbiome, optimize the immune system, reduce food sensitivities, lower cholesterol, reverse type 2 diabetes, improve brain function, and even prevent cancer. Restrictive fad diets starve the gut of the critical fiber we need, weaken the microbes, and make our system vulnerable. As a former junk-food junkie, Dr. B knows firsthand the power of fiber to dramatically transform our health. The good news is that our guts can be trained. Fiber-rich, real foods--with fruits, vegetables, whole grains, seeds, nuts, and legumes--start working quickly and maintain your long-term health, promote weight loss, and allow you to thrive and feel great from the inside out. With a 28-day jumpstart program with menus and more than 65 recipes, along with essential advice on food sensitivities, Fiber Fueled offers the blueprint to start turbocharging your gut for lifelong health today.

Download or read book The Tradition of Science written by Leonard C. Bruno and published by . This book was released on 1987 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Any real understanding of where we stand scientifically today and where we are headed depends to a great extent on an awareness of how we reached those scientific achievements. The increased impact of science and technology on our lives makes such an understanding even more important. For this reason, this book is intended to provide information about the major works of science in the collections of the Library of Congress. These selected works are organized here by traditional scientific discipline and are treated in historical and, generally, chronological order. The contents contain chapters on: (1) astronomy; (2) botany; (3) zoology; (4) medicine; (5) chemistry; (6) geology; (7) mathematics; and (8) physics. A bibliography provides information about particular Library of Congress collections to which a book or manuscript may belong, as well as specific bibliographic information. Title translations are also included. (TW)

Download or read book SALAMANDERS OF THE FAMILY PLETHODONTIDAE written by EMMETT REID. DUNN and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Powerful Partnerships written by Karen L. Mapp and published by Scholastic Professional. This book was released on 2017-07-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Teachers and administrators will learn how to create the respectful, trusting relationships with families necessary to build the educational partnerships that best support children's learning. The book will cover the mindset and core beliefs required to bond with families, and will provide guidance on how to plan engagement opportunities and events throughout the school year that undergird effective partnerships between families and schools.