Download or read book Prostate Cancer and the Search for Novel Biomarkers written by Taha Alexander Haj-Ahmad and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Identification of Therapeutic Targets and Novel Biomarkers in Prostate Cancer written by Shashwat Sharad and published by Frontiers Media SA. This book was released on 2023-02-08 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cell Molecular Biology of Prostate Cancer written by Heide Schatten and published by Springer. This book was released on 2018-09-18 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers classic and modern cell and molecular biology of prostate cancer, as well as novel biomarkers, inflammation, centrosome pathologies, microRNAs, cancer initiation novel biomarkers, inflammation, centrosome pathologies, microRNAs, cancer initiation and genetics, epigenetics, mitochondrial dysfunctions and apoptosis, cancer stem cells, angiogenesis and progression to metastasis, and treatment strategies including clinical trials related to prostate cancer. Cell & Molecular Biology of Prostate Cancer is one of two companion books comprehensively addressing the biology and clinical aspects of prostate cancer. Prostate Cancer: Molecular & Diagnostic Imaging and Treatment Stategies, the companion volume, discusses both classic and the most recent imaging approaches including analysis of needle biopsies, applications of nanoparticle probes and peptide-based radiopharmaceuticals for detection, early diagnosis and treatment of prostate cancer. Taken together, these volumes form one comprehensive and invaluable contribution to the literature.

Download or read book Advances in Cancer Biomarkers written by Roberto Scatena and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: At present there are a growing number of biomolecules under investigation to understand their potential role as cancer biomarker for diagnostic, prognostic and therapeutic purposes. Intriguingly, the state of art on cancer biomarkers research shows interesting and promising results together to clamorous failures. Also from a clinical point of view, there are contradictory results on routine clinical use of the present cancer biomarkers. Some patients may be simply monitored in their course by a periodic blood sample, but sometimes this monitoring shows dramatic limits. A lot of patients show serious and extensive relapses without significant change in serum concentrations of biomarkers tested. Often the physician who should utilize these biomarker does not entirely know their limits and the total potential applications as well and sometimes this knowledge is influenced by economical and marketing strategies. This limited and "polluted" knowledge may have dramatic consequences for patient. The aim of this book is to diffuse all aspects of cancer biomarkers, from their biochemical peculiarities to all clinical implications by passing through their physiology and pathophysiology. This critical approach towards old and new cancer biomarkers should foster a deepened and useful understanding of the diagnostic and prognostic index of these fundamental parameters of laboratory medicine and in the same time facilitating the research of new and more sensitive-specific signals of the cancer cell proliferation.

Download or read book The Identification of Novel Biomarkers in the Development and Progression of Early Prostate Cancer written by Krishan K. Rasiah and published by . This book was released on 2006 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Diagnostic Prognostic and Predictive Biomarkers in Prostate Cancer written by Carsten Stephan and published by MDPI. This book was released on 2018-06-27 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Diagnostic, Prognostic and Predictive Biomarkers in Prostate Cancer" that was published in IJMS

Download or read book Circulating Biomarkers In Prostate Cancer written by Yafeng Ma and published by Frontiers Media SA. This book was released on 2024-02-27 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the era of precision oncology, liquid biopsy techniques, specifically the use of circulating tumor cells (CTCs), cell free circulating tumor DNA (ctDNA) and extracellular vesicles particularly exosomes, represent a paradigm shift in the conventional use of tissue based biomarkers. Compared to tissue biopsy, liquid biopsy is cost-effective, readily accessible and less invasive, minimizing the bias of sampling and offering the opportunity for serial monitoring. Circulating biomarkers detected in liquid biopsy (blood and urine, etc.) are helping in understanding cancer genomic landscape and evolution, thus have been largely studied in term of cancer screening, risk stratification and early detection of minimal residual disease. Castration-resistant prostate cancers (CRPCs) are the late stage of prostate cancers. With significant progress towards the treatment of CRPCs, for example, androgen receptor-signalling (ARS) targeted therapy and immunotherapy, there is an urgent need to identify novel biomarkers to improve the survival rate and prognosis of CRPCs. The study of such biomarkers associated signal pathways and immune status has become a major focus in research to help understanding the responses to drug resistance and ineffective treatments. The discovery of these biomarkers in selecting potentially responsive patients will improve outcomes, and reduce treatment costs and, most importantly, significantly improve patient’s quality of life.

Download or read book Diagnostic Prognostic and Predictive Biomarkers in Prostate Cancer written by Carsten Stephan and published by . This book was released on 2017 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnostic, Prognostic and Predictive Biomarkers in Prostate Cancer.

Download or read book Prostate Cancer Prevention written by Jack Cuzick and published by Springer Science & Business Media. This book was released on 2014-02-15 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely. A wide range of topics are covered by leading authorities in the field. The biology and natural history of prostate cancer are reviewed and the role of lifestyle and dietary factors, assessed. Detailed attention is paid to risk prediction biomarkers and to the role of novel high-throughput nucleic acid-based technologies in improving risk prediction and thereby allowing tailored approaches to cancer prevention. Potential means of chemoprevention of prostate cancer are also reviewed in depth, covering the very positive new data on the impact of aspirin as well as evidence regarding 5α-reductase inhibitors, DFMO and lycopene. Guidance is provided on the differentiation of aggressive from indolent disease and the policy and research implications of recent findings are examined. This book will be of interest to both clinicians and researchers.

Download or read book Prostate Cancer written by Gordana Kocic and published by Springer Nature. This book was released on with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Use of Classical and Novel Biomarkers as Prognostic Risk Factors for Localised Prostate Cancer written by Paul Sutcliffe and published by . This book was released on 2009 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Novel Therapeutics and Biomarkers For Human Prostate Cancer written by Gerhardt Attard and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Evaluating Novel Prognostic Biomarkers in Prostate Cancer written by Benjamin Scott Simpson and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Identification and Validation of Novel Prostate Cancer Biomarkers written by Saeid Alinezhad and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Identification of Novel Prostate Cancer Biomarkers Using High throughput Technologies written by René Böttcher and published by . This book was released on 2016 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Identifying Novel Molecular Biomarkers and Therapeutic Targets for Prostate Cancer written by Tanushree Shenoy and published by . This book was released on 2017 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostate cancer is the most common malignancy in males, and the third leading cause of male cancer-related death in the Western world. Although most prostate cancers are diagnosed at an early and treatable stages, predicting the outcome of prostate cancer progression and treatment has proven to be challenging because of the heterogeneous nature of the disease. Recent cancer genome studies have identified novel alterations as well as the potential actionable targets. Among these novel alterations is chromodomain helicase DNA-binding protein 1 (CHD1). CHD1 deletion occurs in as many as 20% of prostate cancers and may be associated with genomic instability. To validate the function of CHD1 in prostate cancer in vivo, we created the Pb-Cre+;Chd1L/L mouse model, whereby Chd1 is deleted in mouse prostate epithelial cells, and engineered CHD1-deleted prostate cancer cell lines. We found that while Chd1 deletion alone does not induce prostate cancer in vivo, it confers DNA damage sensitivity and homologous recombination impairment, making CHD1-deficient cells sensitive to PARP inhibitors and Platinum-based drugs. A metastatic castrate-resistant prostate cancer patient whose tumors had CHD1 deletion was responsive to carboplatin, suggesting that CHD1 status may be a biomarker for PARP inhibitor and platinum treatment responsiveness.

Download or read book Biomarkers in Cancer Screening and Early Detection written by Sudhir Srivastava and published by John Wiley & Sons. This book was released on 2017-08-28 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prepared by world leaders on this topic, Biomarkers in Cancer Screening and Early Detection offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers, from their discovery and development to their validation, clinical utility, and use in developing personalized cancer treatment. Offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers Provides immediately actionable information – and hopefully also inspiration – to move discovery and clinical application forward Offers vital knowledge to help develop personalized cancer treatment for individual patients with specific cancers