Download or read book Prostaglandins and Fertility Regulation written by M. Toppozada and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: The role of prostaglandins in physiological events and pathological disorders related to human reproduction has been most actively investigated in the past decade. Their clinical use for fertility regulation, extensively evaluated, represents the most common clinical indication for the administration of these remarkable compounds. Thus, it is most appropriate to update the available information related to the use of prostaglandins in the regulation of human fertility to provide a background document for the benefit of clinicians and scientists. Invited experts of international reputation from various parts of the world have contributed, each in his own area of interest, to offer this book, which we hope will fill an existing gap. M. T. M. B. E. S. E. H. ix 1 Potential for prostaglandin use in controlling human reproduction K. T. KIRTON and F. A. KIMBALL BACKGROUND It was observed in 1930 that seminal plasma of a number of species contained very large amounts of substance(s) capable of altering uterine motility. These substances were subsequently demonstrated to be prostaglandins (PGs); this began the early and continued association of this group of compounds with reproduction. The activity was found to be associated with a fraction containing lipid-soluble acids, derived from prostanoic acid. Restrictions imposed by obscure sources and small amounts of material available for testing were initially impediments to their study.
Download or read book The Prostaglandins in Human Reproduction written by Mostyn P. Embrey and published by . This book was released on 1975 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Population Reports written by and published by . This book was released on 1975 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Prostaglandin Abstracts written by Ronald A. Shalita and published by Springer. This book was released on 1975-01-05 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostagtandin Abstracts Volume II contains abstracts of the significant scientific Iiterature published in 1971, 1972, and 1973 on the role of prostaglandins in human reproduction. Of the more than 4000 articles which were published between 1971 and 1973 and deal with prostaglandins, endogenous and exogenous, in mal es and females, nearly 1100 involve human reproduction. Prostagtandin Abstracts, Volume I (Plenum Publishers, 1973) contains abstracts of all articles on prostaglandins published between 1906, when the action of these compounds was first noted, and 1970, when clinical research with these compounds was weil underway. Clinical use of prostaglandins during the 1960s proved safe but provided evidence of troublesome side effects. Du ring the 1970s, the development of new analogues, various protocols for international testing, and improved routes of administration indicates that prostaglandins still hold promise as a useful drug in the management of fertility. Research into potential contraceptive and other clinical uses of prostaglandins continues to be an exciting and expanding field of fundamental and clinical research. The citations and abstracts which are included in this volume have been selected and reproduced from POPINFORM, a computerized on-line information retrieval system which includes in its data base more than 25,000 documents on regulation of fertility. Also included as an Appendix is a bibliography (without abstracts) of 1971 -1973 material on aspects of prostaglandin research that do not involve reproduction. This bibliography was prepared by the Upjohn Company of Kalamazoo, Michigan and is printed here with permission.
Download or read book Recent Advances in Fertility Control written by Seiichi Matsumoto and published by . This book was released on 1987 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Prostaglandins and Fertility Regulation written by Elsayed Saad Eldin Hafez and published by . This book was released on 1984 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Third Conference on Prostaglandins in Fertility Control written by Sune Bergström and published by . This book was released on 1972 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Prostaglandins and the Uterus written by James O. Drife and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: The introduction of prostaglandins into clinical practice has been one of the most important advances in obstetrics and gynaecology in recent years. During the last decade obstetricians have become familiar with these drugs for inducing labour and for terminating second-trimester pregnancy. Within the last year their use has been extended, in association with antiprogestin, to first-trimester termi nation. Although the effectiveness of prostaglandins in these pharma cological roles is clear, their full potential has still to be explored, and much remains to be learned about their physiology. Prostaglandins playa central role in the initiation of labour. Further clarification of this role could lead to improvements in preventing or treating preterm labour, which still remains the most important cause of perinatal mortality in this country. Prostaglandins are also inti mately involved in the mechanism of menstruation. More detailed understanding of this role should lead to more effective treatments for menorrhagia and dysmenorrhoea. These substances also playa part in the mechanism of implantation, and further research in this area may lead to more effective therapy for infertility.
Download or read book Contraceptive Research and Development written by Institute of Medicine and published by National Academies Press. This book was released on 1996-11-04 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: The "contraceptive revolution" of the 1960s and 1970s introduced totally new contraceptive options and launched an era of research and product development. Yet by the late 1980s, conditions had changed and improvements in contraceptive products, while very important in relation to improved oral contraceptives, IUDs, implants, and injectables, had become primarily incremental. Is it time for a second contraceptive revolution and how might it happen? Contraceptive Research and Development explores the frontiers of science where the contraceptives of the future are likely to be found and lays out criteria for deciding where to make the next R&D investments. The book comprehensively examines today's contraceptive needs, identifies "niches" in those needs that seem most readily translatable into market terms, and scrutinizes issues that shape the market: method side effects and contraceptive failure, the challenge of HIV/AIDS and other sexually transmitted diseases, and the implications of the "women's agenda." Contraceptive Research and Development analyzes the response of the pharmaceutical industry to current dynamics in regulation, liability, public opinion, and the economics of the health sector and offers an integrated set of recommendations for public- and private-sector action to meet a whole new generation of demand.
Download or read book Bibliography on the Control and Management of the Coyote and Related Canids with Selected References on Animal Physiology Behaviour Control Methods and Reproduction written by E. H. Dolnick and published by . This book was released on 1976 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Antiprogestin Steroid RU 486 and Human Fertility Control written by Etienne-Emile Baulieu and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in basic biological research have proceeded rapidly in recent years. The fields of molecular genetics and immunology have experienced dramatic breakthroughs, capturing the imagination of both the scientific community and the general public. With less public notice, receptor biology has brought a cascade of new discoveries and insights. The entire science of pharmacology has been virtually rewritten in terms of receptor phenomenology. In particular, the discovery of specific receptors for steroid and protein hormones has been of seminal importance. With this new information, we have advanced our understanding of the mechanism and specifity of hormone action. We can now explain how hormones interact selectively with specific target cells and how hormones alter biochemical events within the target cells. These facts have already impacted on applied problems of clinical medicine, particularly in diagnosis and treatment of cancer and some metabolic diseases. Now, a new and important application of basic receptor biology and chemistry looms ahead. Within a few short years since the discovery of the progesterone receptor, chemists have synthesized molecules with a greater affinity for the receptor than progesterone itself and which, while occupying the receptor, fail to trigger the events which transform a target cell from the unstimulated to the stimulated state. This is the basis of the competitive inhibitory action of the anti-progestational agent, synthesized by the chemists at Roussel Uc1af, Paris, and designated RU 486.
Download or read book Human Fertility Control written by D F Hawkins and published by Butterworth-Heinemann. This book was released on 2013-10-22 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Fertility Control: Theory and Practice reviews the theoretical and practical concepts of human fertility control and covers topics ranging from hormonal contraception and barrier methods to intra-uterine contraception, legal abortion, and sterilization. Family planning is also discussed, with emphasis on contraception in patients with medical disorders. Comprised of 21 chapters divided into seven sections, this book begins with an introduction to hormonal contraceptives, including the oral ones such as combined pills, sequential pills, and low-dose progestagen pills, along with injectable hormones and implants. The following chapters explore the clinical pharmacology of estrogens and progestagens; combined oral contraceptives; and the relative effectiveness and risks of hormonal contraception. Barrier methods such as condoms, spermicides, and coitus interruptus (male withdrawal) are also described. The remaining chapters examine intra-uterine devices and complications of intra-uterine contraception; issues surrounding legal abortion; and methods of operative sterilization. This monograph will be a valuable resource for obstetricians and gynecologists, medical and postgraduate students, nurses and midwives concerned with family planning, and specialists in training.
Download or read book Prostaglandins and their Inhibitors in Clinical Obstetrics and Gynaecology written by M. Bygdeman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is clear today that several prostaglandins play an important role in the regulation of many of the physiological events of the reproductive organs in the human. Both naturally occurring prostaglandins and their analogues are used routinely in many countries to ripen the cervix and induce labour at term as well as to dilate the cervix and to terminate pregnancy. Prostaglandin biosynthesis inhibitors are widely used in the treatment of primary dysmenorrhoea. The editors have aimed at an accurate, thorough, yet easily under standable review of the status in 1986 of medical knowledge regarding both the physiological importance and the clinical use of prostaglan dins and their inhibitors in obstetrics and gynaecology. I believe this book will be of value for all clinicians concerned with reproductive health. The list of authors guarantees an authoritative and up-to-date review of this active field. SUNE BERGSTROM Karolinska Institutet, Stockholm, Sweden Table Examples of clinical use of natural prostaglandins and some prostaglandin analogues Indications Prostaglandin Route of administration Manufacturer Dilatation of the cervix prior 15-methyl-PGF • Intramuscular Upjohn, USA 2 to vacuum aspiration 16-phenoxy-PGE methyl sulphonylamide Intramuscular Schering AG, West Germany 2 16,16-dimethyl-PGE methyl ester 1 Vaginal ONO, Japan; May & Baker, UK Second trimester abortion Intra -amniotic Upjohn, USA; ONO, Japan PGF 20 Upjohn, USA PGE Vaginal 2 Upjohn, USA 15-methyl-PGF 2.
Download or read book Endocrine Mechanisms in Fertility Regulation written by Giuseppe Benagiano and published by . This book was released on 1983 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Male Fertility and Its Regulation written by E.S. Hafez and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uncontrolled population growth, a significant problem for many countries, depresses real living standards in all developing areas. As a corollary, un controlled population growth also stresses the ability to deliver adequate reproductive health care on both national and individual levels. To focus on this and related problems an International Congress to examine many aspects of male and female Reproductive Health Center Care was held on 10-15 October 1982 in Maui, Hawaii, USA. This volume is a result of the proceedings from the 'Symposium on Male Fertility and its Regulation' which was a part of the Reproductive Health Care Congress. The organizers of this symposium recognized the need to focus male reproductive understanding on contraceptive development. The ultimate objective was and still is to produce a variety of safe and effective male contraceptives similar to that accomplished in the female. Speakers were invited to review the state of the art in several areas related to male contra ception, reproductive toxicity and reproductive biology. The abstracts of these sessions were published as a special issue of Archives of Andrology (Vol. 9, No.1, August, 1982). Subsequently, this volume was assembled from key papers presented at the Symposium. Additionally, invited man uscripts from leaders in specific areas were solicited to provide additional range to the topics covered.
Download or read book Population Sciences written by and published by . This book was released on 1977 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1991 with total page 1460 pages. Available in PDF, EPUB and Kindle. Book excerpt:
